(Q48087583)

8 February 2018

title

ApoE and clusterin cooperatively suppress Abeta levels and deposition: evidence that ApoE regulates extracellular Abeta metabolism in vivo. (English)

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8 February 2018

main subject

Apolipoprotein E

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GOA release 2020-03-11

Clusterin

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GOA release 2020-03-11

11

David M Holtzman

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8 February 2018

8

Bruce J Aronow

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8 February 2018

author name string

Ronald B DeMattos

1

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8 February 2018

John R Cirrito

2

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8 February 2018

Maia Parsadanian

3

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8 February 2018

Patrick C May

4

1 reference

8 February 2018

Mark A O'Dell

5

1 reference

8 February 2018

Jennie W Taylor

6

1 reference

8 February 2018

Judith A K Harmony

7

1 reference

8 February 2018

Kelly R Bales

9

1 reference

8 February 2018

Steven M Paul

10

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8 February 2018

language of work or name

English

0 references

publication date

1 January 2004

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8 February 2018

published in

Neuron

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8 February 2018

volume

41

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8 February 2018

issue

2

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8 February 2018

page(s)

193-202

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8 February 2018

Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition.

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7 January 2021

Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease

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7 January 2021

Apolipoprotein E isoform-specific reduction of extracellular amyloid in neuronal cultures.

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7 January 2021

Co-expression of beta-amyloid precursor protein (betaAPP) and apolipoprotein E in cell culture: analysis of betaAPP processing

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7 January 2021

Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins.

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7 January 2021

Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system

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7 January 2021

Fibrillogenesis in Alzheimer's disease of amyloid beta peptides and apolipoprotein E.

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7 January 2021

In VivoAssessment of Brain Interstitial Fluid with Microdialysis Reveals Plaque-Associated Changes in Amyloid-β Metabolism and Half-Life

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7 January 2021

Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease

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7 January 2021

Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease

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7 January 2021

Brain to plasma amyloid-beta efflux: a measure of brain amyloid burden in a mouse model of Alzheimer's disease.

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7 January 2021

Plaque-associated disruption of CSF and plasma amyloid-beta (Abeta) equilibrium in a mouse model of Alzheimer's disease.

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7 January 2021

Clusterin promotes amyloid plaque formation and is critical for neuritic toxicity in a mouse model of Alzheimer's disease

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7 January 2021

Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

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7 January 2021

Human and murine ApoE markedly alters A beta metabolism before and after plaque formation in a mouse model of Alzheimer's disease.

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7 January 2021

Apolipoprotein E markedly facilitates age-dependent cerebral amyloid angiopathy and spontaneous hemorrhage in amyloid precursor protein transgenic mice.

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7 January 2021

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

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7 January 2021

The cerebrospinal-fluid soluble form of Alzheimer's amyloid beta is complexed to SP-40,40 (apolipoprotein J), an inhibitor of the complement membrane-attack complex

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7 January 2021

Apolipoprotein E epsilon 4 and cerebral hemorrhage associated with amyloid angiopathy

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7 January 2021

Interaction of apolipoprotein J-amyloid beta-peptide complex with low density lipoprotein receptor-related protein-2/megalin. A mechanism to prevent pathological accumulation of amyloid beta-peptide

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7 January 2021

Clusterin contributes to caspase-3-independent brain injury following neonatal hypoxia-ischemia.

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7 January 2021

Role of apoe/Abeta interactions in the pathogenesis of Alzheimer's disease and cerebral amyloid angiopathy

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7 January 2021

Expression of human apolipoprotein E reduces amyloid-beta deposition in a mouse model of Alzheimer's disease

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7 January 2021

Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease

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7 January 2021

Protein chemical and immunocytochemical studies of meningovascular beta-amyloid protein in Alzheimer's disease and normal aging.

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7 January 2021

Amyloid precursor protein processing and A beta42 deposition in a transgenic mouse model of Alzheimer disease

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7 January 2021

Purification of apolipoprotein E attenuates isoform-specific binding to beta-amyloid

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7 January 2021

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

1 reference

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7 January 2021

Amyloid-associated proteins α1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments

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7 January 2021

Apolipoprotein J and Alzheimer's amyloid beta solubility

1 reference

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7 January 2021

Sulfated glycoprotein 2: new relationships of this multifunctional protein to neurodegeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900850-X

7 January 2021

Apolipoprotein J/clusterin limits the severity of murine autoimmune myocarditis

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900850-X

7 January 2021

In vivo calibration of microdialysis probes for exogenous compounds

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900850-X

7 January 2021

High frequency of apolipoprotein E ?2 Allele in hemorrhage due to cerebral amyloid angiopathy

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900850-X

7 January 2021

Clusterin (apoJ) alters the aggregation of amyloid beta-peptide (A beta 1-42) and forms slowly sedimenting A beta complexes that cause oxidative stress.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900850-X

7 January 2021

Opposite roles of apolipoprotein E in normal brains and in Alzheimer's disease.

1 reference

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7 January 2021

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

1 reference

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7 January 2021

Alzheimer's disease: genes, proteins, and therapy

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7 January 2021

Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier

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7 January 2021

Alzheimer's disease: perspectives for the new millennium

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7 January 2021

Identification and transport of full-length amyloid precursor proteins in rat peripheral nervous system.

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7 January 2021

Molecular biology of apolipoprotein E.

1 reference

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7 January 2021

Apolipoprotein E and Alzheimer's disease

1 reference

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7 January 2021

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

1 reference

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7 January 2021

Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease

1 reference

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7 January 2021

Glial fibrillary acidic protein-apolipoprotein E (apoE) transgenic mice: astrocyte-specific expression and differing biological effects of astrocyte-secreted apoE3 and apoE4 lipoproteins.

1 reference

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7 January 2021

Lipidation of apolipoprotein E influences its isoform-specific interaction with Alzheimer's amyloid beta peptides

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900850-X

7 January 2021

Apolipoprotein E: a pathological chaperone protein in patients with cerebral and systemic amyloid

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900850-X

7 January 2021

Biology of A beta amyloid in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900850-X

7 January 2021

Apolipoprotein E promotes the binding and uptake of beta-amyloid into Chinese hamster ovary cells in an isoform-specific manner

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900850-X

7 January 2021

Glycoprotein 330/megalin: probable role in receptor-mediated transport of apolipoprotein J alone and in a complex with Alzheimer disease amyloid beta at the blood-brain and blood-cerebrospinal fluid barriers

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900850-X

7 January 2021

10.1016/S0896-6273(03)00850-X

Identifiers

DOI

1 reference

8 February 2018

PubMed ID

14741101

1 reference

8 February 2018