(Q38058245)

27 August 2017

Signalling danger: endoplasmic reticulum stress and the unfolded protein response in pancreatic islet inflammation (English)

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27 August 2017

endoplasmic reticulum

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author name string

D L Eizirik

series ordinal

1

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27 August 2017

M Miani

series ordinal

2

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27 August 2017

A K Cardozo

series ordinal

3

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27 August 2017

7 November 2012

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27 August 2017

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27 August 2017

56

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27 August 2017

2

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27 August 2017

234-241

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https://scigraph.springernature.com/pub.10.1007/s00125-012-2762-3

27 August 2017

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cites work

ER stress in pancreatic beta cells: the thin red line between adaptation and failure

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The role for endoplasmic reticulum stress in diabetes mellitus

21 January 2018

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Endoplasmic reticulum stress, obesity and diabetes

21 January 2018

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Inflammatory mechanisms in obesity

21 January 2018

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Regulation of innate immunity by signaling pathways emerging from the endoplasmic reticulum

21 January 2018

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The role of inflammation in insulitis and beta-cell loss in type 1 diabetes

21 January 2018

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The unfolded protein response: from stress pathway to homeostatic regulation

21 January 2018

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Modulating stress responses by the UPRosome: a matter of life and death

21 January 2018

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Control of NF-κB and inflammation by the unfolded protein response

21 January 2018

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The interplay between endoplasmic reticulum stress and inflammation.

21 January 2018

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Endoplasmic reticulum stress and the inflammatory basis of metabolic disease

21 January 2018

1 reference

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XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2762-3

Palmitate induces a pro-inflammatory response in human pancreatic islets that mimics CCL2 expression by beta cells in type 2 diabetes

21 January 2018

1 reference

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Preconditioning with endoplasmic reticulum stress mitigates retinal endothelial inflammation via activation of X-box binding protein 1.

21 January 2018

1 reference

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ER stress depresses NF-kappaB activation in mesangial cells through preferential induction of C/EBP beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2762-3

Resistance to type 2 diabetes mellitus: a matter of hormesis?

21 January 2018

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TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2762-3

Mild endoplasmic reticulum stress augments the proinflammatory effect of IL-1β in pancreatic rat β-cells via the IRE1α/XBP1s pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2762-3

Nitric oxide-induced apoptosis in pancreatic beta cells is mediated by the endoplasmic reticulum stress pathway

21 January 2018

1 reference

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Cytokines downregulate the sarcoendoplasmic reticulum pump Ca2+ ATPase 2b and deplete endoplasmic reticulum Ca2+, leading to induction of endoplasmic reticulum stress in pancreatic beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2762-3

Transcriptional regulation of the endoplasmic reticulum stress gene chop in pancreatic insulin-producing cells

21 January 2018

1 reference

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Differential regulation of adaptive and apoptotic unfolded protein response signalling by cytokine-induced nitric oxide production in mouse pancreatic beta cells

21 January 2018

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C/EBP homologous protein contributes to cytokine-induced pro-inflammatory responses and apoptosis in β-cells

21 January 2018

1 reference

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Cytokines suppress human islet function irrespective of their effects on nitric oxide generation

21 January 2018

1 reference

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Exposure of human islets to cytokines can result in disproportionately elevated proinsulin release

21 January 2018

1 reference

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Initiation and execution of lipotoxic ER stress in pancreatic beta-cells

21 January 2018

1 reference

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Interferon-gamma potentiates endoplasmic reticulum stress-induced death by reducing pancreatic beta cell defence mechanisms

21 January 2018

1 reference

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Pancreatic β-cells depend on basal expression of active ATF6α-p50 for cell survival even under nonstress conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2762-3

Role for activating transcription factor 3 in stress-induced beta-cell apoptosis

21 January 2018

1 reference

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High expression rates of human islet amyloid polypeptide induce endoplasmic reticulum stress mediated beta-cell apoptosis, a characteristic of humans with type 2 but not type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2762-3

Islet β-cell endoplasmic reticulum stress precedes the onset of type 1 diabetes in the nonobese diabetic mouse model

21 January 2018

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Glucose regulated proteins 78 protects insulinoma cells (NIT-1) from death induced by streptozotocin, cytokines or cytotoxic T lymphocytes

21 January 2018

1 reference

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Regulation of CCAAT/enhancer-binding protein homologous protein (CHOP) expression by interleukin-1 beta in pancreatic beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2762-3

Bcl-2 proteins in diabetes: mitochondrial pathways of β-cell death and dysfunction

21 January 2018

1 reference

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The role of CHOP messenger RNA expression in the link between oxidative stress and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2762-3

Crosstalk in NF-κB signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2762-3

Endoplasmic reticulum calcium depletion impacts chaperone secretion, innate immunity, and phagocytic uptake of cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2762-3

Regulation of glucose homeostasis through a XBP-1-FoxO1 interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2762-3

Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2762-3

Cytokine-induced beta-cell death is independent of endoplasmic reticulum stress signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2762-3

Positive role of CCAAT/enhancer-binding protein homologous protein, a transcription factor involved in the endoplasmic reticulum stress response in the development of colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2762-3

The human pancreatic islet transcriptome: expression of candidate genes for type 1 diabetes and the impact of pro-inflammatory cytokines

21 January 2018

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Molecular chaperones and protein-folding catalysts as intercellular signaling regulators in immunity and inflammation.

21 January 2018

1 reference

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Thioredoxin-interacting protein mediates ER stress-induced β cell death through initiation of the inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2762-3

IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2762-3

Lack of TXNIP protects against mitochondria-mediated apoptosis but not against fatty acid-induced ER stress-mediated beta-cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2762-3

Weight gain in early life predicts risk of islet autoimmunity in children with a first-degree relative with type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2762-3

Insulin resistance is a risk factor for progression to type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2762-3

Expression of endoplasmic reticulum stress markers in the islets of patients with type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2762-3

Endoplasmic reticulum stress and pancreatic β-cell death

21 January 2018

1 reference

12 December 2020

Childhood body mass index (BMI), breastfeeding and risk of Type 1 diabetes: findings from a longitudinal national birth cohort

1 reference

12 December 2020

Deletion of C/EBP homologous protein (Chop) in C57Bl/6 mice dissociates obesity from insulin resistance

1 reference

12 December 2020

CHOP deletion does not impact the development of diabetes but suppresses the early production of insulin autoantibody in the NOD mouse

1 reference

12 December 2020

C/EBP homologous protein deficiency attenuates myocardial reperfusion injury by inhibiting myocardial apoptosis and inflammation

1 reference

12 December 2020

C/EBP homologous protein (CHOP) is crucial for the induction of caspase-11 and the pathogenesis of lipopolysaccharide-induced inflammation

1 reference

12 December 2020

Cytokine-induced proapoptotic gene expression in insulin-producing cells is related to rapid, sustained, and nonoscillatory nuclear factor-kappaB activation

1 reference

12 December 2020

10.1007/S00125-012-2762-3

Identifiers

DOI

1 reference

Dimensions Publication ID

27 August 2017

1027958834

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Fatcat ID

release_gr6j4jzuafclbn2cpxrbpoa7ua

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/gr6j4jzuafclbn2cpxrbpoa7ua

24 November 2022

mapped directly with Wikidata item

1 reference