(Q38075770)

28 August 2017

1 reference

title

The role of hepatokines in metabolism (English)

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28 August 2017

2

Hans-Ulrich Häring

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28 August 2017

1

Norbert Stefan

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28 August 2017

publication date

22 January 2013

1 reference

Nature Reviews Endocrinology

28 August 2017

published in

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28 August 2017

volume

9

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28 August 2017

issue

3

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28 August 2017

page(s)

144-152

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https://scigraph.springernature.com/pub.10.1038/nrendo.2012.258

28 August 2017

exact match

0 references

cites work

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Adipokines in inflammation and metabolic disease

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Muscles, exercise and obesity: skeletal muscle as a secretory organ

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Insulin signalling and the regulation of glucose and lipid metabolism

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Macrophages, inflammation, and insulin resistance

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The role of endoplasmic reticulum in hepatic lipid homeostasis and stress signaling

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Type 2 diabetes across generations: from pathophysiology to prevention and management

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Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome

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Obesity: glypican-4: role in insulin signalling

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A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

31 March 2020

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Genetic Variations inPPARDandPPARGC1ADetermine Mitochondrial Function and Change in Aerobic Physical Fitness and Insulin Sensitivity during Lifestyle Intervention

31 March 2020

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Variations inPPARDDetermine the Change in Body Composition during Lifestyle Intervention: A Whole-Body Magnetic Resonance Study

31 March 2020

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Short-term exercise training does not stimulate skeletal muscle ATP synthesis in relatives of humans with type 2 diabetes

31 March 2020

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High cardiorespiratory fitness is an independent predictor of the reduction in liver fat during a lifestyle intervention in non-alcoholic fatty liver disease

31 March 2020

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Identification and characterization of metabolically benign obesity in humans

31 March 2020

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Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity

31 March 2020

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Causes and metabolic consequences of Fatty liver

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Mechanisms of Disease: hepatic steatosis in type 2 diabetes--pathogenesis and clinical relevance

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Review: The role of insulin resistance in nonalcoholic fatty liver disease

31 March 2020

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Fatty liver: a novel component of the metabolic syndrome

31 March 2020

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Risk of cardiovascular disease in patients with nonalcoholic fatty liver disease

31 March 2020

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Viewpoints on the way to a consensus session: where does insulin resistance start? The liver

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Role of obesity and lipotoxicity in the development of nonalcoholic steatohepatitis: pathophysiology and clinical implications

31 March 2020

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Relationship between hepatic/visceral fat and hepatic insulin resistance in nondiabetic and type 2 diabetic subjects.

31 March 2020

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Fatty liver index and mortality: the Cremona study in the 15th year of follow-up.

31 March 2020

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Mechanism of free fatty acid-induced insulin resistance in humans

31 March 2020

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Alterations in postprandial hepatic glycogen metabolism in type 2 diabetes

31 March 2020

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Hepatic glucose metabolism in humans--its role in health and disease

31 March 2020

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Brain insulin action augments hepatic glycogen synthesis without suppressing glucose production or gluconeogenesis in dogs.

31 March 2020

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Lipid-induced insulin resistance: unravelling the mechanism

31 March 2020

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The problem of establishing relationships between hepatic steatosis and hepatic insulin resistance

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Inflammation and lipid signaling in the etiology of insulin resistance

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Human fatty liver disease: old questions and new insights

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

31 March 2020

Diabetic dyslipidaemia

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https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Inflammation and metabolic disorders

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Identification of a lipokine, a lipid hormone linking adipose tissue to systemic metabolism

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

A proposed new paradigm for insulin resistance

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Genes involved in oxidative phosphorylation are coordinately upregulated with fasting hyperglycaemia in livers of patients with type 2 diabetes.

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB

31 March 2020

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31 March 2020

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Serum levels of angiopoietin-related growth factor in diabetes mellitus and chronic hemodialysis

31 March 2020

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Tissue distribution and activity testing suggest a similar but not identical function of fetuin-B and fetuin-A

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Characterization of a natural inhibitor of the insulin receptor tyrosine kinase: cDNA cloning, purification, and anti-mitogenic activity

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

The nucleotide and partial amino acid sequences of rat fetuin. Identity with the natural tyrosine kinase inhibitor of the rat insulin receptor

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Bovine fetuin is an inhibitor of insulin receptor tyrosine kinase

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Alpha2-HSG, a specific inhibitor of insulin receptor autophosphorylation, interacts with the insulin receptor

31 March 2020

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The "thrifty" gene encoding Ahsg/Fetuin-A meets the insulin receptor: Insights into the mechanism of insulin resistance

31 March 2020

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Improved insulin sensitivity and resistance to weight gain in mice null for the Ahsg gene

31 March 2020

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A synonymous coding polymorphism in the alpha2-Heremans-schmid glycoprotein gene is associated with type 2 diabetes in French Caucasians

31 March 2020

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AHSG tag single nucleotide polymorphisms associate with type 2 diabetes and dyslipidemia: studies of metabolic traits in 7,683 white Danish subjects

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Alpha2-Heremans-Schmid glycoprotein/fetuin-A is associated with insulin resistance and fat accumulation in the liver in humans.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Fetuin-A and its relation to metabolic syndrome and fatty liver disease in obese children before and after weight loss

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Fetuin A in nonalcoholic fatty liver disease: in vivo and in vitro studies.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

NF-kappaB mediates lipid-induced fetuin-A expression in hepatocytes that impairs adipocyte function effecting insulin resistance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

High glucose induces transactivation of the alpha2-HS glycoprotein gene through the ERK1/2 signaling pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

High plasma fetuin-A is associated with increased carotid intima-media thickness in a middle-aged population

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Plasma fetuin-A is associated with endothelial dysfunction and subclinical atherosclerosis in subjects with nonalcoholic fatty liver disease.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Association between human fetuin-A and the metabolic syndrome: data from the Heart and Soul Study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Association of serum fetuin-A with insulin resistance in type 2 diabetic and nondiabetic subjects

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

The impact of liver fat vs visceral fat in determining categories of prediabetes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Serum fetuin-A is correlated with metabolic syndrome in middle-aged and elderly Chinese

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Serum fetuin-A is an independent marker of insulin resistance in Japanese men.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Cardiometabolic correlates and heritability of fetuin-A, retinol-binding protein 4, and fatty-acid binding protein 4 in the Framingham Heart Study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Plasma fetuin-A levels and the risk of type 2 diabetes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Fetuin-A and incident diabetes mellitus in older persons

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Association of fetuin-a with incident diabetes mellitus in community-living older adults: the cardiovascular health study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Plasma levels of fetuin-A and hepatic enzymes and risk of type 2 diabetes in women in the U.S.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Fetuin-A induces cytokine expression and suppresses adiponectin production

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Fetuin-A acts as an endogenous ligand of TLR4 to promote lipid-induced insulin resistance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Fetuin-A: the missing link in lipid-induced inflammation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Plasma fetuin-a levels and the risk of myocardial infarction and ischemic stroke

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Association of AHSG Gene Polymorphisms With Fetuin-A Plasma Levels and Cardiovascular Diseases in the EPIC-Potsdam Study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

FGF-21 as a novel metabolic regulator

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Research resource: Comprehensive expression atlas of the fibroblast growth factor system in adult mouse.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Endocrine fibroblast growth factors 15/19 and 21: from feast to famine

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

The role of liver-derived insulin-like growth factor-I.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Unraveling insulin-like growth factor binding protein-3 actions in human disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Comparison of the metabolic effects of recombinant human insulin-like growth factor-I and insulin. Dose-response relationships in healthy young and middle-aged adults

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Recombinant human insulin-like growth factor I increases insulin sensitivity and improves glycemic control in type II diabetes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Insulin-like growth factor axis and risk of type 2 diabetes in women

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Nonalcoholic fatty liver disease is associated with low circulating levels of insulin-like growth factor-I.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Hepatic gene networks in morbidly obese patients with nonalcoholic fatty liver disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

A liver-derived secretory protein, selenoprotein P, causes insulin resistance.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Serum selenoprotein P levels in patients with type 2 diabetes and prediabetes: implications for insulin resistance, inflammation, and atherosclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Inverse correlation between serum levels of selenoprotein P and adiponectin in patients with type 2 diabetes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

SECRETION OF TESTOSTERONE-ESTRADIOL-BINDING GLOBULIN BY A HUMAN HEPATOMA-DERIVED CELL LINE

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Sex hormone-binding globulin and risk of type 2 diabetes in women and men

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Sex-hormone-binding globulin and the free androgen index are related to cardiovascular risk factors in multiethnic premenopausal and perimenopausal women enrolled in the Study of Women Across the Nation (SWAN).

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Potential role of tumor necrosis factor-α in downregulating sex hormone-binding globulin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

IL1β down-regulation of sex hormone-binding globulin production by decreasing HNF-4α via MEK-1/2 and JNK MAPK pathways

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Sex Hormone–Binding Globulin and Risk of Type 2 Diabetes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Increased androgen bioavailability is associated with non-alcoholic fatty liver disease in women with polycystic ovary syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Relationships of circulating sex hormone-binding globulin with metabolic traits in humans

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Sex hormone-binding globulin is synthesized in target cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Sex hormone-binding globulin mediates steroid hormone signal transduction at the plasma membrane

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Sex hormone-binding globulin and type 2 diabetes mellitus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

The diagnosis and management of non-alcoholic fatty liver disease: practice guideline by the American Gastroenterological Association, American Association for the Study of Liver Diseases, and American College of Gastroenterology

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Non-alcoholic steatohepatitis and cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Nonalcoholic fatty liver disease and hepatocellular carcinoma: a weighty connection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Dissociation between fatty liver and insulin resistance in humans carrying a variant of the patatin-like phospholipase 3 gene

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

A common variant in PNPLA3, which encodes adiponutrin, is associated with liver fat content in humans

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

PNPLA3 variants specifically confer increased risk for histologic nonalcoholic fatty liver disease but not metabolic disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

The metabolically benign and malignant fatty liver

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2012.258

Monosaccharide-induced lipogenesis regulates the human hepatic sex hormone-binding globulin gene

31 March 2020

1 reference

12 December 2020

The role of interleukin-6 in insulin resistance, body fat distribution and energy balance

1 reference

12 December 2020

Serum alpha 2-HS-glycoprotein is an inhibitor of the human insulin receptor at the tyrosine kinase level

1 reference

12 December 2020

Basic research: Irisin--behind the benefits of exercise

1 reference

12 December 2020

The stress response of the liver to physical exercise.

1 reference

12 December 2020

Sex hormone-binding globulin. Binding to cell membranes and generation of a second messenger

1 reference

12 December 2020

Insulin-like growth factors and their binding proteins: biological actions

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRENDO.2012.258

1 reference

28 August 2017

1 reference