(Q38077510)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23359405%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

review article

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title

RB1 in cancer: different mechanisms of RB1 inactivation and alterations of pRb pathway in tumorigenesis (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23359405%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1

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22 February 2020

Antonella D'Anneo

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23359405%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

3

Giovanni Tesoriere

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23359405%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

4

Renza Vento

1 reference

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22 February 2020

language of work or name

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1 August 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23359405%20AND%20SRC:MED&resulttype=core&format=json

Journal of Cellular Physiology

22 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23359405%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

volume

228

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22 February 2020

issue

8

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22 February 2020

page(s)

1676-1687

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Retinoblastoma in the 20th century: past success and future challenges the Weisenfeld lecture

22 February 2020

cites work

1 reference

Complex transcriptional regulatory mechanisms control expression of the E2F3 locus

21 January 2018

1 reference

Cdk2 and Cdk4 regulate the centrosome cycle and are critical mediators of centrosome amplification in p53-null cells.

21 January 2018

1 reference

Clinical significance of P16INK4A and retinoblastoma proteins in non-small-cell lung carcinoma.

21 January 2018

1 reference

Chromosome aberrations in solid tumors

21 January 2018

1 reference

NEDDylation controls the target specificity of E2F1 and apoptosis induction.

21 January 2018

1 reference

Rb depletion results in deregulation of E-cadherin and induction of cellular phenotypic changes that are characteristic of the epithelial-to-mesenchymal transition.

21 January 2018

1 reference

Induction of ZEB proteins by inactivation of RB protein is key determinant of mesenchymal phenotype of breast cancer.

21 January 2018

1 reference

A novel repressive E2F6 complex containing the polycomb group protein, EPC1, that interacts with EZH2 in a proliferation-specific manner

21 January 2018

1 reference

Constitutional and somatic RB1 mutation spectrum in nonfamilial unilateral and bilateral retinoblastoma in India.

21 January 2018

1 reference

Mullerian Inhibiting Substance inhibits cervical cancer cell growth via a pathway involving p130 and p107.

21 January 2018

1 reference

The retinoblastoma protein tumor suppressor is important for appropriate osteoblast differentiation and bone development

21 January 2018

1 reference

Transformation of human and murine fibroblasts without viral oncoproteins

21 January 2018

1 reference

E2F target genes: unraveling the biology

21 January 2018

1 reference

Retinoblastoma protein recruits histone deacetylase to repress transcription

21 January 2018

1 reference

Direct transcriptional repression by pRB and its reversal by specific cyclins

21 January 2018

1 reference

Phosphorylation of the retinoblastoma-related protein p130 in growth-arrested cells.

21 January 2018

1 reference

Role of LXCXE motif-dependent interactions in the activity of the retinoblastoma protein

21 January 2018

1 reference

Hyperphosphorylation of pRb: a mechanism for RB tumour suppressor pathway inactivation in bladder cancer

21 January 2018

1 reference

Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product

21 January 2018

1 reference

Emerging roles of E2Fs in cancer: an exit from cell cycle control

21 January 2018

1 reference

Making sense of cancer genomic data

21 January 2018

1 reference

E2f1-3 switch from activators in progenitor cells to repressors in differentiating cells

21 January 2018

1 reference

The Rb family contains a conserved cyclin-dependent-kinase-regulated transcriptional repressor motif

21 January 2018

1 reference

p107 and p130: versatile proteins with interesting pockets

21 January 2018

1 reference

The retinoblastoma family: twins or distant cousins?

21 January 2018

1 reference

Pocket proteins and cell cycle control

21 January 2018

1 reference

Gene amplification in human gliomas

21 January 2018

1 reference

Cooperation between Rb and Arf in suppressing mouse retinoblastoma.

21 January 2018

1 reference

One hit, two hits, three hits, more? Genomic changes in the development of retinoblastoma.

21 January 2018

1 reference

Frequent loss of pRb2/p130 in human ovarian carcinoma

21 January 2018

1 reference

Epithelial ovarian cancer: the role of cell cycle genes in the different histotypes

21 January 2018

1 reference

Paclitaxel and beta-lapachone synergistically induce apoptosis in human retinoblastoma Y79 cells by downregulating the levels of phospho-Akt.

21 January 2018

1 reference

Differentiative pathway activated by 3-aminobenzamide, an inhibitor of PARP, in human osteosarcoma MG-63 cells.

21 January 2018

1 reference

Modeling the effect of the RB tumor suppressor on disease progression: dependence on oncogene network and cellular context

21 January 2018

1 reference

How the Rb tumor suppressor structure and function was revealed by the study of Adenovirus and SV40.

21 January 2018

1 reference

E2F8 contributes to human hepatocellular carcinoma via regulating cell proliferation.

21 January 2018

1 reference

Loss of RB1 induces non-proliferative retinoma: increasing genomic instability correlates with progression to retinoblastoma.

21 January 2018

1 reference

Physical interaction of the retinoblastoma protein with human D cyclins

21 January 2018

1 reference

The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest

21 January 2018

1 reference

Emerging insights into the molecular and cellular basis of glioblastoma

21 January 2018

1 reference

The regulation of E2F by pRB-family proteins

21 January 2018

1 reference

A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma

21 January 2018

1 reference

Unusual proliferation arrest and transcriptional control properties of a newly discovered E2F family member, E2F-6

21 January 2018

1 reference

E2F4 is exported from the nucleus in a CRM1-dependent manner.

21 January 2018

1 reference

Cell cycle control and beyond: emerging roles for the retinoblastoma gene family

21 January 2018

1 reference

Role of insulin-like growth factors in autocrine growth of human retinoblastoma Y79 cells

21 January 2018

1 reference

Loss of 9p leads to p16INK4A down-regulation and enables RB/E2F1-dependent cell cycle promotion in gastrointestinal stromal tumours (GISTs).

21 January 2018

1 reference

Deficiency of pRb family proteins and p53 in invasive urothelial tumorigenesis.

21 January 2018

1 reference

The retinoblastoma family of proteins and their regulatory functions in the mammalian cell division cycle

21 January 2018

1 reference

The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F

21 January 2018

1 reference

Molecular detection of chromosomal translocations that disrupt the putative retinoblastoma susceptibility locus

21 January 2018

1 reference

E2F-5, a new E2F family member that interacts with p130 in vivo

21 January 2018

1 reference

Structure of the human retinoblastoma gene

21 January 2018

1 reference

Inactivation of the Rb pathway and overexpression of both isoforms of E2F3 are obligate events in bladder tumours with 6p22 amplification.

21 January 2018

1 reference

E2F2 represses cell cycle regulators to maintain quiescence.

21 January 2018

1 reference

Molecular changes in mesothelioma with an impact on prognosis and treatment

21 January 2018

1 reference

Expression of retinoblastoma protein and P16 proteins in classic Hodgkin lymphoma: relationship with expression of p53 and presence of Epstein-Barr virus in the regulation of cell growth and death

21 January 2018

1 reference

Mutation and cancer: statistical study of retinoblastoma

21 January 2018

1 reference

E2F5 status significantly improves malignancy diagnosis of epithelial ovarian cancer

21 January 2018

1 reference

Isolation of human chromosome 13-specific DNA sequences cloned from flow sorted chromosomes and potentially linked to the retinoblastoma locus

21 January 2018

1 reference

Atypical E2Fs: new players in the E2F transcription factor family

21 January 2018

1 reference

Emerging roles of DNA tumor viruses in cell proliferation: new insights into genomic instability.

21 January 2018

1 reference

Human retinoblastoma susceptibility gene: cloning, identification, and sequence.

21 January 2018

1 reference

The retinoblastoma protein binds to a family of E2F transcription factors

21 January 2018

1 reference

Synergistic function of E2F7 and E2F8 is essential for cell survival and embryonic development.

21 January 2018

1 reference

Evolutionarily conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence

21 January 2018

1 reference

Downregulation of CDKN2A and suppression of cyclin D1 gene expressions in malignant gliomas

21 January 2018

1 reference

E2F-7: a distinctive E2F family member with an unusual organization of DNA-binding domains

21 January 2018

1 reference

Insights from mouse models into human retinoblastoma

21 January 2018

1 reference

Effect of promoter methylation of the p16 gene on phosphorylation of retinoblastoma gene product and growth of hepatocellular carcinoma cells

21 January 2018

1 reference

E2F-4 switches from p130 to p107 and pRB in response to cell cycle reentry

21 January 2018

1 reference

Protein expression of the RB-related gene family and SV40 large T antigen in mesothelioma and lung cancer

21 January 2018

1 reference

BRCA1: the enigma of tissue-specific tumor development.

21 January 2018

1 reference

E2F7 and E2F8 keep the E2F family in balance

21 January 2018

1 reference

Cyclin D1 overexpression, p16 loss, and pRb inactivation play a key role in pulmonary carcinogenesis and have a prognostic implication for the long-term survival in non-small cell lung carcinoma patients

21 January 2018

1 reference

G1 to S phase cell cycle transition in somatic and embryonic stem cells.

21 January 2018

1 reference

CDKN2A gene deletions and loss of p16 expression occur in osteosarcomas that lack RB alterations

21 January 2018

1 reference

E2F6 negatively regulates BRCA1 in human cancer cells without methylation of histone H3 on lysine 9.

21 January 2018

1 reference

Inhibition of pituitary tumors in Rb mutant chimeras through E2f4 loss reveals a key suppressive role for the pRB/E2F pathway in urothelium and ganglionic carcinogenesis

21 January 2018

1 reference

9p21 locus analysis in high-risk gastrointestinal stromal tumors characterized for c-kit and platelet-derived growth factor receptor alpha gene alterations.

21 January 2018

1 reference

Measurement of blood E2F3 mRNA in prostate cancer by quantitative RT-PCR: a preliminary study

21 January 2018

1 reference

A role for E2F6 in the restriction of male-germ-cell-specific gene expression

21 January 2018

1 reference

Clinical relevance of E2F family members in ovarian cancer--an evaluation in a training set of 77 patients

21 January 2018

1 reference

Sensitive and efficient detection of RB1 gene mutations enhances care for families with retinoblastoma

21 January 2018

1 reference

Dissecting Pin1 and phospho-pRb regulation.

21 January 2018

1 reference

p107 is a suppressor of retinoblastoma development in pRb-deficient mice

21 January 2018

1 reference

21 January 2018

1 reference

Role of the retinoblastoma protein in the pathogenesis of human cancer

21 January 2018

1 reference

The INK4A/ARF locus and its two gene products

21 January 2018

1 reference

pRb inactivation in mammary cells reveals common mechanisms for tumor initiation and progression in divergent epithelia

21 January 2018

1 reference

Cancer risk in patients with constitutional chromosome deletions: a nationwide British cohort study

21 January 2018

1 reference

Perturbation of Rb, p53, and Brca1 or Brca2 cooperate in inducing metastatic serous epithelial ovarian cancer

21 January 2018

1 reference

The E2F5 repressor is an activator of E6/E7 transcription and of the S-phase entry in HPV18-associated cells

21 January 2018

1 reference

RB1 gene mutation up-date, a meta-analysis based on 932 reported mutations available in a searchable database

21 January 2018

1 reference

The electroencephalogram (EEG) as a research tool in human behavior genetics: psychological examinations in healthy males with various inherited EEG variants. I. Rationale of the study. Material. Methods. Heritability of test parameters

21 January 2018

1 reference

Molecular classification identifies a subset of human papillomavirus--associated oropharyngeal cancers with favorable prognosis

21 January 2018

1 reference

Rb is critical in a mammalian tissue stem cell population

21 January 2018

1 reference

E2F7 represses a network of oscillating cell cycle genes to control S-phase progression

21 January 2018

1 reference

The retinoblastoma protein is required for Ras-induced oncogenic transformation

21 January 2018

1 reference

A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma

21 January 2018

1 reference

E2F1-mediated apoptosis as a target of cancer therapy

21 January 2018

1 reference

Extra-embryonic function of Rb is essential for embryonic development and viability

21 January 2018

1 reference

Novel link between E2F1 and Smac/DIABLO: proapoptotic Smac/DIABLO is transcriptionally upregulated by E2F1.

21 January 2018

1 reference

Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation

21 January 2018

1 reference

A cluster of cooperating tumor-suppressor gene candidates in chromosomal deletions

21 January 2018

1 reference

Somatic inactivation of genes on chromosome 13 is a common event in retinoblastoma

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/JCP.24329

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23359405%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference