(Q38081169)

28 August 2017

Th17 cell development: from the cradle to the grave (English)

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28 August 2017

Luis A Zúñiga

1

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28 August 2017

Renu Jain

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2

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28 August 2017

Christopher Haines

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3

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28 August 2017

Daniel J Cua

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4

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28 August 2017

1 March 2013

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28 August 2017

Immunological Reviews

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28 August 2017

252

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28 August 2017

1

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28 August 2017

78-88

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Differential activity of IL-12 and IL-23 in mucosal and systemic innate immune pathology.

28 August 2017

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Regulation of interleukin-12/interleukin-23 production and the T-helper 17 response in humans

21 January 2018

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Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12

21 January 2018

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The structure of interleukin-23 reveals the molecular basis of p40 subunit sharing with interleukin-12

21 January 2018

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A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R

21 January 2018

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Innate IL-17-producing cells: the sentinels of the immune system

21 January 2018

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Signalling, inflammation and arthritis: crossed signals: the role of interleukin (IL)-12, -17, -23 and -27 in autoimmunity.

21 January 2018

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Crohn's disease: Th1, Th17 or both? The change of a paradigm: new immunological and genetic insights implicate Th17 cells in the pathogenesis of Crohn's disease

21 January 2018

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Transcriptional regulatory networks in Th17 cell differentiation

21 January 2018

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Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5

21 January 2018

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RORgammat and commensal microflora are required for the differentiation of mucosal interleukin 22-producing NKp46+ cells

21 January 2018

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IL-17 in protective immunity to intracellular pathogens

21 January 2018

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Barrier immunity and IL-17.

21 January 2018

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Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

21 January 2018

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Interleukin-23 drives intestinal inflammation through direct activity on T cells

21 January 2018

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Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation

21 January 2018

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IL-23 induces spondyloarthropathy by acting on ROR-γt+ CD3+CD4-CD8- entheseal resident T cells

21 January 2018

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IL-23 is increased in dendritic cells in multiple sclerosis and down-regulation of IL-23 by antisense oligos increases dendritic cell IL-10 production

21 January 2018

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The increased expression of IL-23 in inflammatory bowel disease promotes intraepithelial and lamina propria lymphocyte inflammatory responses and cytotoxicity

21 January 2018

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Increased Interleukin 21 (IL-21) and IL-23 Are Associated with Increased Disease Activity and with Radiographic Status in Patients with Early Rheumatoid Arthritis

21 January 2018

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Development, cytokine profile and function of human interleukin 17-producing helper T cells

21 January 2018

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Current investigational drugs in psoriasis

21 January 2018

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Transforming growth factor-beta induces development of the T(H)17 lineage

21 January 2018

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TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

21 January 2018

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Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

21 January 2018

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The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo

21 January 2018

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Generation of pathogenic T(H)17 cells in the absence of TGF-β signalling

21 January 2018

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STAT3 regulates cytokine-mediated generation of inflammatory helper T cells

21 January 2018

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Diverse targets of the transcription factor STAT3 contribute to T cell pathogenicity and homeostasis.

21 January 2018

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Impaired T(H)17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome

21 January 2018

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Dominant-negative mutations in the DNA-binding domain of STAT3 cause hyper-IgE syndrome

21 January 2018

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Loss of STAT3 in CD4+ T cells prevents development of experimental autoimmune diseases

21 January 2018

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The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

21 January 2018

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TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology

21 January 2018

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Transforming growth factor beta is dispensable for the molecular orchestration of Th17 cell differentiation

21 January 2018

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TGF-beta1 inhibits T-bet induction by IFN-gamma in murine CD4+ T cells through the protein tyrosine phosphatase Src homology region 2 domain-containing phosphatase-1.

21 January 2018

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IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways

21 January 2018

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Induction and molecular signature of pathogenic TH17 cells

21 January 2018

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Fate mapping of IL-17-producing T cells in inflammatory responses

21 January 2018

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Cutting edge: IL-23 receptor gfp reporter mice reveal distinct populations of IL-17-producing cells

21 January 2018

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The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF.

21 January 2018

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RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation.

21 January 2018

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Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells

21 January 2018

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IL-27 blocks RORc expression to inhibit lineage commitment of Th17 cells

21 January 2018

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Differential effect of IL-27 on developing versus committed Th17 cells.

21 January 2018

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Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation

21 January 2018

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Thymic self-reactivity selects natural interleukin 17-producing T cells that can regulate peripheral inflammation

21 January 2018

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Selection of self-reactive T cells in the thymus

21 January 2018

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Regulatory T-cell differentiation versus clonal deletion of autoreactive thymocytes

21 January 2018

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Transforming growth factor-beta signaling curbs thymic negative selection promoting regulatory T cell development

21 January 2018

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iNKT cell development is orchestrated by different branches of TGF-beta signaling

21 January 2018

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Control of the development of CD8αα+ intestinal intraepithelial lymphocytes by TGF-β.

21 January 2018

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Autonomous role of medullary thymic epithelial cells in central CD4(+) T cell tolerance

21 January 2018

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The requirements for natural Th17 cell development are distinct from those of conventional Th17 cells

21 January 2018

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Developmental plasticity of Th17 and Treg cells.

21 January 2018

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The interleukin-4 enhancer CNS-2 is regulated by Notch signals and controls initial expression in NKT cells and memory-type CD4 T cells.

21 January 2018

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Natural occurring IL-17 producing T cells regulate the initial phase of neutrophil mediated airway responses.

21 January 2018

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T-lineage cells require the thymus but not VDJ recombination to produce IL-17A and regulate granulopoiesis in vivo

21 January 2018

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Interleukin-12 promotes gamma interferon-dependent neutrophil recruitment in the lung and improves protection against respiratory Streptococcus pneumoniae infection

21 January 2018

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Interferon-gamma coordinates CCL3-mediated neutrophil recruitment in vivo

21 January 2018

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Cot/Tpl2 regulates IL-23 p19 expression in LPS-stimulated macrophages through ERK activation.

21 January 2018

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On natural and artificial vaccinations

21 January 2018

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Origins of CD4(+) effector and central memory T cells

21 January 2018

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Central memory and effector memory T cell subsets: function, generation, and maintenance

21 January 2018

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Asymmetric T lymphocyte division in the initiation of adaptive immune responses.

21 January 2018

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Memory CD4 T cells emerge from effector T-cell progenitors.

21 January 2018

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CD4(+) T cell effectors can become memory cells with high efficiency and without further division.

21 January 2018

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Generation and maintenance of memory CD4(+) T Cells

21 January 2018

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Memory CD4+ T cells: fate determination, positive feedback and plasticity

21 January 2018

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Interferons direct Th2 cell reprogramming to generate a stable GATA-3(+)T-bet(+) cell subset with combined Th2 and Th1 cell functions.

21 January 2018

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Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient mice

21 January 2018

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Th17 cells promote pancreatic inflammation but only induce diabetes efficiently in lymphopenic hosts after conversion into Th1 cells.

21 January 2018

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Late developmental plasticity in the T helper 17 lineage

21 January 2018

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Paths to stemness: building the ultimate antitumour T cell.

21 January 2018

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Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells

21 January 2018

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Phenotypic and functional features of human Th17 cells

21 January 2018

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Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation

21 January 2018

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Human TH17 cells are long-lived effector memory cells.

21 January 2018

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Different routes of bacterial infection induce long-lived TH1 memory cells and short-lived TH17 cells

21 January 2018

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Th17 cells mediate clade-specific, serotype-independent mucosal immunity

21 January 2018

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Vaccine-induced th17 cells are maintained long-term postvaccination as a distinct and phenotypically stable memory subset

21 January 2018

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Control of TH17 cells occurs in the small intestine.

21 January 2018

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Differential glycosylation of TH1, TH2 and TH-17 effector cells selectively regulates susceptibility to cell death

21 January 2018

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The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/IMR.12036

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28 August 2017

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