(Q38084436)

28 August 2017

title

Neurosteroids as regenerative agents in the brain: therapeutic implications (English)

1 reference

28 August 2017

Roberta D Brinton

1

1 reference

28 August 2017

publication date

26 February 2013

1 reference

Nature Reviews Endocrinology

28 August 2017

published in

1 reference

28 August 2017

volume

9

1 reference

28 August 2017

issue

4

1 reference

28 August 2017

page(s)

241-250

1 reference

https://scigraph.springernature.com/pub.10.1038/nrendo.2013.31

28 August 2017

exact match

0 references

cites work

Neurosteroids, with special reference to the effect of progesterone on myelination in peripheral nerves

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Neuroactive steroids: an update of their roles in central and peripheral nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Neurosteroids: biochemistry and clinical significance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Neural mechanisms of ageing and cognitive decline

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Neurodegenerative diseases: new concepts of pathogenesis and their therapeutic implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Division-coupled astrocytic differentiation and age-related depletion of neural stem cells in the adult hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

When neurogenesis encounters aging and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Quiescent and active hippocampal neural stem cells with distinct morphologies respond selectively to physiological and pathological stimuli and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Allopregnanolone restores hippocampal-dependent learning and memory and neural progenitor survival in aging 3xTgAD and nonTg mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Allopregnanolone reverses neurogenic and cognitive deficits in mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Impaired adult neurogenesis in the dentate gyrus of a triple transgenic mouse model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

The healthy cell bias of estrogen action: mitochondrial bioenergetics and neurological implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Estrogen-induced plasticity from cells to circuits: predictions for cognitive function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Allopregnanolone levels are reduced in temporal cortex in patients with Alzheimer's disease compared to cognitively intact control subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Multiple functions of type 10 17beta-hydroxysteroid dehydrogenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Cell cycle regulation in the postmitotic neuron: oxymoron or new biology?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Progesterone synthesis in the nervous system: implications for myelination and myelin repair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Allopregnanolone increases the number of dopaminergic neurons in substantia nigra of a triple transgenic mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

The neurosteroid allopregnanolone promotes proliferation of rodent and human neural progenitor cells and regulates cell-cycle gene and protein expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Adult-born hippocampal dentate granule cells undergoing maturation modulate learning and memory in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Impaired cell proliferation in the subventricular zone in an Alzheimer's disease model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Disruption of neurogenesis in the subventricular zone of adult mice, and in human cortical neuronal precursor cells in culture, by amyloid beta-peptide: implications for the pathogenesis of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Resolving new memories: a critical look at the dentate gyrus, adult neurogenesis, and pattern separation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Neurogenesis may relate to some but not all types of hippocampal-dependent learning

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Neurogenesis in the adult is involved in the formation of trace memories

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Alzheimer's disease as homeostatic responses to age-related myelin breakdown

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

White matter integrity and cortical metabolic associations in aging and dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Diffusion tensor imaging in preclinical and presymptomatic carriers of familial Alzheimer's disease mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Shift in brain metabolism in late onset Alzheimer's disease: implications for biomarkers and therapeutic interventions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Allopregnanolone promotes regeneration and reduces β-amyloid burden in a preclinical model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Triple-transgenic Alzheimer's disease mice exhibit region-specific abnormalities in brain myelination patterns prior to appearance of amyloid and tau pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Clinical and biomarker changes in dominantly inherited Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Epidemiology of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Brain imaging in the study of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

The Alzheimer's Disease Neuroimaging Initiative: a review of papers published since its inception.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

A specific amyloid-beta protein assembly in the brain impairs memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

The secretases: enzymes with therapeutic potential in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Lipid metabolism and neuroinflammation in Alzheimer's disease: a role for liver X receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Mechanisms underlying the rapid peroxisome proliferator-activated receptor-γ-mediated amyloid clearance and reversal of cognitive deficits in a murine model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Liver X receptor activation enhances cholesterol loss from the brain, decreases neuroinflammation, and increases survival of the NPC1 mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

The LXR agonist TO901317 selectively lowers hippocampal Abeta42 and improves memory in the Tg2576 mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Pregnane X receptor (PXR) activation: a mechanism for neuroprotection in a mouse model of Niemann-Pick C disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

PXR, CAR and drug metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Cholesterol oxidation products are sensitive and specific blood-based biomarkers for Niemann-Pick C1 disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Predominantly neuronal expression of cytochrome P450 isoforms CYP3A11 and CYP3A13 in mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Oxidative stress in NPC1 deficient cells: protective effect of allopregnanolone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Impaired neurosteroid synthesis in multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Niemann-Pick type C disease involves disrupted neurosteroidogenesis and responds to allopregnanolone

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Allopregnanolone reinstates tyrosine hydroxylase immunoreactive neurons and motor performance in an MPTP-lesioned mouse model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Neurosteroid replacement therapy for catamenial epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Neurosteroids: endogenous regulators of the GABA(A) receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Allopregnanolone impairs episodic memory in healthy women

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Neurogenesis in the adult human hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Endogenous neurosteroids regulate GABAA receptors through two discrete transmembrane sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

A novel site of adult doublecortin expression: neuropeptide neurons within the suprachiasmatic nucleus circadian clock

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Magnetic resonance spectroscopy identifies neural progenitor cells in the live human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

An in vivo correlate of exercise-induced neurogenesis in the adult dentate gyrus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Neural stem cells: disposable, end-state glia?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Role of neuroactive steroids in the peripheral nervous system

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

High cholesterol level is essential for myelin membrane growth

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Chronic allopregnanolone treatment accelerates Alzheimer's disease development in AβPP(Swe)PSEN1(ΔE9) mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Physiological and pathological aspects of Abeta in iron homeostasis via 5'UTR in the APP mRNA and the therapeutic use of iron-chelators

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRENDO.2013.31

Neuroregenerative mechanisms of allopregnanolone in Alzheimer's disease

31 March 2020

1 reference

12 December 2020

Allopregnanolone-induced rise in intracellular calcium in embryonic hippocampal neurons parallels their proliferative potential

1 reference

12 December 2020

Steroid modulation of the chloride ionophore in rat brain: structure-activity requirements, regional dependence and mechanism of action

1 reference

12 December 2020

Neurosteroids: of the nervous system, by the nervous system, for the nervous system.

1 reference

12 December 2020

Allopregnanolone, a progesterone metabolite, enhances behavioral recovery and decreases neuronal loss after traumatic brain injury.

1 reference

12 December 2020

Regulation of xenobiotic and bile acid metabolism by the nuclear pregnane X receptor

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRENDO.2013.31

1 reference

28 August 2017

1 reference