(Q38088360)

English

Implications of endoplasmic reticulum stress, the unfolded protein response and apoptosis for molecular cancer therapy. Part II: targeting cell cycle events, caspases, NF-κB and the proteasome.

scientific article published on 25 June 2009

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23480539%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

Implications of endoplasmic reticulum stress, the unfolded protein response and apoptosis for molecular cancer therapy. Part II: targeting cell cycle events, caspases, NF-κB and the proteasome (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23480539%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

endoplasmic reticulum

0 references

0 references

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23480539%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

author name string

Donavon C Hiss

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23480539%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

language of work or name

0 references

publication date

25 June 2009

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23480539%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

Expert Opinion on Drug Discovery

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23480539%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23480539%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

9

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23480539%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

907-921

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23480539%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

TNF potentiates anticancer activity of bortezomib (Velcade) through reduced expression of proteasome subunits and dysregulation of unfolded protein response

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

The proteasome: a worthwhile target for the treatment of solid tumours?

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

The proteasome inhibitor bortezomib acts differently in combination with p53 gene transfer or cytotoxic chemotherapy on NSCLC cells

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Functions of the proteasome: from protein degradation and immune surveillance to cancer therapy

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Proteasome inhibitors: a therapeutic strategy for haematological malignancy

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Targeting ubiquitin specific proteases for drug discovery

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Highlights in experimental therapeutics

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Fold up or perish: unfolded protein response and chemotherapy

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

The putative roles of the ubiquitin/proteasome pathway in resistance to anticancer therapy

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Proteasome inhibition blocks caspase-8 degradation and sensitizes prostate cancer cells to death receptor-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Sensitization of tumor cells to NK cell-mediated killing by proteasome inhibition

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Molecular-targeted therapies: lessons from years of clinical development

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

ER stress response: getting the UPR hand on misfolded proteins

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Therapeutic anti-cancer targets upstream of the proteasome.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Drug discovery in the ubiquitin-proteasome system.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Proteasome inhibition as novel treatment strategy in leukaemia

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

The proteasome and proteasome inhibitors in cancer therapy

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Proteasome inhibitors: antitumor effects and beyond

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Active-site directed probes to report enzymatic action in the ubiquitin proteasome system.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Mechanisms of delivery of ubiquitylated proteins to the proteasome: new target for anti-cancer therapy?

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Cul4A is required for hematopoietic stem-cell engraftment and self-renewal

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Cul4A is required for hematopoietic cell viability and its deficiency leads to apoptosis

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Ubiquitin-mediated proteasomal degradation in normal and malignant hematopoiesis.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

PERK mediates cell-cycle exit during the mammalian unfolded protein response

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Mammalian unfolded protein response inhibits cyclin D1 translation and cell-cycle progression

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Ribosomal stress couples the unfolded protein response to p53-dependent cell cycle arrest

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

PERK and GCN2 contribute to eIF2alpha phosphorylation and cell cycle arrest after activation of the unfolded protein response pathway

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

A novel role in cytokinesis reveals a housekeeping function for the unfolded protein response

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Curcumin induces the degradation of cyclin E expression through ubiquitin-dependent pathway and up-regulates cyclin-dependent kinase inhibitors p21 and p27 in multiple human tumor cell lines

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Predictive value of GADD153, p21 and c-Jun for chemotherapy response in gastric cancer

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

TNF-alpha promotes Doxorubicin-induced cell apoptosis and anti-cancer effect through downregulation of p21 in p53-deficient tumor cells

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

P21 response to DNA damage induced by genistein and etoposide in human lung cancer cells.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Induction of apoptosis by vinblastine via c-Jun autoamplification and p53-independent down-regulation of p21WAF1/CIP1.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Mechanisms underlying the pro-survival pathway of p53 in suppressing mitotic death induced by adriamycin

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Cell survival, cell death and cell cycle pathways are interconnected: implications for cancer therapy

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

The proteasome inhibitor bortezomib (PS-341) inhibits growth and induces apoptosis in primary effusion lymphoma cells

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Alteration of cell-cycle regulation in epithelial ovarian cancer.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Antisense oligonucleotide targeting p53 increased apoptosis of MCF-7 cells induced by ionizing radiation

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Ubiquitin ligases: cell-cycle control and cancer

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

A redox cycle within the cell cycle: ring in the old with the new.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

The retinoblastoma protein and cell cycle control

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

A systems biology dynamical model of mammalian G1 cell cycle progression

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Antibody engineering: facing new challenges in cancer therapy.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Anticancer therapeutics: "Addictive" targets, multi-targeted drugs, new drug combinations

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Axis of evil: molecular mechanisms of cancer metastasis

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Comparison of deregulated expression of cyclin D1 and cyclin E with that of cyclin-dependent kinase 4 (CDK4) and CDK2 in human oesophageal squamous cell carcinoma

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

5-FdUrd-araC heterodinucleoside re-establishes sensitivity in 5-FdUrd- and AraC-resistant MCF-7 breast cancer cells overexpressing ErbB2.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

The use of cyclin-dependent kinase inhibitors alone or in combination with established cytotoxic drugs in cancer chemotherapy

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Preclinical and clinical development of the cyclin-dependent kinase inhibitor flavopiridol

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Argyrin a reveals a critical role for the tumor suppressor protein p27(kip1) in mediating antitumor activities in response to proteasome inhibition

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

A novel role for a familiar protein in apoptosis induced by proteasome inhibition

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

The ubiquitin-proteasome system and cancer

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Caspases in cell survival, proliferation and differentiation.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Overview of cell death signaling pathways

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Apoptosis: controlled demolition at the cellular level

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Caspase function in programmed cell death

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Delineation of the caspase-9 signaling cascade

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

The COP9 signalosome-mediated deneddylation is stimulated by caspases during apoptosis

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

ER stress and the unfolded protein response

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Endoplasmic reticulum stress and alteration in calcium homeostasis are involved in cadmium-induced apoptosis

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Induction of endoplasmic reticulum stress and apoptosis by a marine prostanoid in human hepatocellular carcinoma.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Genistein induces apoptosis in human hepatocellular carcinomas via interaction of endoplasmic reticulum stress and mitochondrial insult.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Molecular Components of a Cell Death Pathway Activated by Endoplasmic Reticulum Stress

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Coupling endoplasmic reticulum stress to the cell-death program: a novel HSP90-independent role for the small chaperone protein p23

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Endoplasmic reticulum stress induces calcium-dependent permeability transition, mitochondrial outer membrane permeabilization and apoptosis

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Cytotoxic drug-induced, p53-mediated upregulation of caspase-8 in tumor cells

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

3,3'-diindolylmethane (DIM) and its derivatives induce apoptosis in pancreatic cancer cells through endoplasmic reticulum stress-dependent upregulation of DR5.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Resveratrol-induced apoptosis in human breast cancer cells is mediated primarily through the caspase-3-dependent pathway.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Cell death in response to antimetabolites directed at thymidylate synthase

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

The unhydrolyzable fenretinide analogue 4-hydroxybenzylretinone induces the proapoptotic genes GADD153 (CHOP) and Bcl-2-binding component 3 (PUMA) and apoptosis that is caspase- dependent and independent of the retinoic acid receptor

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Valproic acid sensitizes chronic lymphocytic leukemia cells to apoptosis and restores the balance between pro- and antiapoptotic proteins

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Caspase-independent cell death by CD300LF (MAIR-V), an inhibitory immunoglobulin-like receptor on myeloid cells

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Caspases and IAPs: a dance of death ensures cell survival

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Natural agents targeting the alpha7-nicotinic-receptor in NSCLC: a promising prospective in anti-cancer drug development

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

The role of signal transducers and activators of transcription in colon cancer

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Alternative pathways of programmed cell death are activated in cells with defective caspase-dependent apoptosis

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Caspase inhibitors: viral, cellular and chemical

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Drug insight: cancer therapy strategies based on restoration of endogenous cell death mechanisms

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

c-IAP1 cooperates with Myc by acting as a ubiquitin ligase for Mad1.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Alternative UPS drug targets upstream the 26S proteasome

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Small-molecule XIAP antagonist restores caspase-9 mediated apoptosis in XIAP-positive diffuse large B-cell lymphoma cells

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Bcl-2 antagonists interact synergistically with bortezomib in DLBCL cells in association with JNK activation and induction of ER stress

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Chemotherapy regimen GOLF induces apoptosis in colon cancer cells through multi-chaperone complex inactivation and increased Raf-1 ubiquitin-dependent degradation

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Ciglitazone induces caspase-independent apoptosis through down-regulation of XIAP and survivin in human glioma cells

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Aminoflavone induces oxidative DNA damage and reactive oxidative species-mediated apoptosis in breast cancer cells

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

p53 gain-of-function cancer mutants induce genetic instability by inactivating ATM.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Classic and novel roles of p53: prospects for anticancer therapy

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

New approaches to molecular cancer therapeutics

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

New targets and challenges in the molecular therapeutics of cancer

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Endoplasmic reticulum stress: cell life and death decisions.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

NF-kappaB: linking inflammation and immunity to cancer development and progression

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Endoplasmic reticulum stress increases the expression of methylenetetrahydrofolate reductase through the IRE1 transducer

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Activation signal of nuclear factor-kappa B in response to endoplasmic reticulum stress is transduced via IRE1 and tumor necrosis factor receptor-associated factor 2

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Signal transduction of inflammatory cytokines and tumor development

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Proteasome inhibitor induces apoptosis through induction of endoplasmic reticulum stress.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

A20 inhibits NF-kappaB activation by dual ubiquitin-editing functions

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Regulation of apoptosis proteins in cancer cells by ubiquitin

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

NF-kappaB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Targeting BCL-2 overexpression in various human malignancies through NF-kappaB inhibition by the proteasome inhibitor bortezomib

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Targeting NF-kappaB pathway with an IKK2 inhibitor induces inhibition of multiple myeloma cell growth

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Synergistic interaction of the histone deacetylase inhibitor SAHA with the proteasome inhibitor bortezomib in mantle cell lymphoma

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

RNA aptamer-targeted inhibition of NF-kappa B suppresses non-small cell lung cancer resistance to doxorubicin.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Inhibition of the NF-kappaB survival pathway via caspase-dependent cleavage of the IKK complex scaffold protein and NF-kappaB essential modulator NEMO.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Can NF-kappaB be a target for novel and efficient anti-cancer agents?

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

The ubiquitin-proteasome system: a novel target for anticancer and anti-inflammatory drug research.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Proteasome as an emerging therapeutic target in cancer

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Proteasome: an emerging target for cancer therapy

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Repression of Dmp1 and Arf transcription by anthracyclins: critical roles of the NF-kappaB subunit p65.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Apoptosis induced by proteasome inhibition in cancer cells: predominant role of the p53/PUMA pathway

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Targeting the ubiquitin-proteasome pathway in cancer therapy

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Epoxomicin, a potent and selective proteasome inhibitor, exhibits in vivo antiinflammatory activity

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

A novel function of VCP (valosin-containing protein; p97) in the control of N-glycosylation of proteins in the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

A phase 2 study of bortezomib in relapsed, refractory myeloma

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Bortezomib or high-dose dexamethasone for relapsed multiple myeloma

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Bortezomib: proteasome inhibition as an effective anticancer therapy

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

New drugs for myeloma

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Antitumor effects and drug interactions of the proteasome inhibitor bortezomib (PS341) in gastric cancer cells

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Preclinical evaluation of the proteasome inhibitor bortezomib in cancer therapy

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Bortezomib as an antitumor agent.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Aggravated endoplasmic reticulum stress as a basis for enhanced glioblastoma cell killing by bortezomib in combination with celecoxib or its non-coxib analogue, 2,5-dimethyl-celecoxib

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

BCL-2 family regulation by the 20S proteasome inhibitor bortezomib

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Proteasome inhibitor PS-341 induces apoptosis in cisplatin-resistant squamous cell carcinoma cells by induction of Noxa

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Endoplasmic reticulum stress-induced apoptosis: multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Tumor cell-selective regulation of NOXA by c-MYC in response to proteasome inhibition.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Proteasome inhibition in multiple myeloma: therapeutic implication

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Combination of proteasome inhibitors bortezomib and NPI-0052 trigger in vivo synergistic cytotoxicity in multiple myeloma

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Ubiquitylation and cancer development

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Bortezomib in relapsed or refractory Waldenström's macroglobulinemia

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Oblimersen sodium (G3139 Bcl-2 antisense oligonucleotide) therapy in Waldenstrom's macroglobulinemia: A targeted approach to enhance apoptosis

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Early results of a phase I trial of oblimersen sodium for relapsed or refractory Waldenstrom's macroglobulinemia

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Novel biologically based therapies for Waldenstrom's macroglobulinemia

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Resveratrol exerts antiproliferative activity and induces apoptosis in Waldenström's macroglobulinemia

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Bortezomib in the treatment of cancer

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Potential new therapeutics for Waldenstrom's macroglobulinemia

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Endoplasmic reticulum stress is a target for therapy in Waldenstrom macroglobulinemia.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Protective role of Hsp27 protein against gamma radiation-induced apoptosis and radiosensitization effects of Hsp27 gene silencing in different human tumor cells

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Hsp27 modulates p53 signaling and suppresses cellular senescence

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Intracellular and extracellular functions of heat shock proteins: repercussions in cancer therapy.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Combination of tunicamycin with anticancer drugs synergistically enhances their toxicity in multidrug-resistant human ovarian cystadenocarcinoma cells

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Regulation of the stability of P-glycoprotein by ubiquitination

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Bortezomib in combination with intermediate-dose dexamethasone and continuous low-dose oral cyclophosphamide for relapsed multiple myeloma

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

A pivotal role for Mcl-1 in Bortezomib-induced apoptosis

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Bortezomib is synergistic with rituximab and cyclophosphamide in inducing apoptosis of mantle cell lymphoma cells in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Diminished feedback regulation of proteasome expression and resistance to proteasome inhibitors in breast cancer cells

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Increased expression and altered subunit composition of proteasomes induced by continuous proteasome inhibition establish apoptosis resistance and hyperproliferation of Burkitt lymphoma cells

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Circulating proteasome levels are an independent prognostic factor for survival in multiple myeloma

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Role of the ubiquitin-proteasome pathway in the diagnosis of human diseases

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Targeting the ubiquitin-proteasome system for cancer therapy

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Ritonavir induces endoplasmic reticulum stress and sensitizes sarcoma cells toward bortezomib-induced apoptosis

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Bortezomib (VELCADE) in metastatic breast cancer: pharmacodynamics, biological effects, and prediction of clinical benefits

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Can the pharmaceutical industry reduce attrition rates?

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Enhanced tumor cell kill by combined treatment with a small-molecule antagonist of mouse double minute 2 and adenoviruses encoding p53.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Synergistic cytotoxic activity of recombinant TRAIL plus the non-genotoxic activator of the p53 pathway nutlin-3 in acute myeloid leukemia cells

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

The MDM-2 antagonist nutlin-3 promotes the maturation of acute myeloid leukemic blasts

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Nongenotoxic activation of the p53 pathway as a therapeutic strategy for multiple myeloma

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Concomitant inhibition of MDM2 and Bcl-2 protein function synergistically induce mitochondrial apoptosis in AML.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

How to design multi-target drugs.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Use of RNA in drug design

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Elevated gadd153/chop expression during resveratrol-induced apoptosis in human colon cancer cells.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Cross-talk between two apoptotic pathways activated by endoplasmic reticulum stress: differential contribution of caspase-12 and AIF.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Intact apoptosis signaling in myeloid leukemia cells determines treatment outcome in childhood AML

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Proteomic Analysis of Waldenstrom Macroglobulinemia

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Antiangiogenic Activity of the MDM2 Antagonist Nutlin-3

1 reference

https://api.crossref.org/works/10.1517%2F17460440903055032

21 January 2018

Identifiers

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q38088360&oldid=2091239144"