(Q38090433)

28 August 2017

Context-specific regulation of cancer epigenomes by histone and transcription factor methylation (English)

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28 August 2017

2

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28 August 2017

I Talianidis

3

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author name string

M Sarris

series ordinal

1

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PubMed ID

23503463

28 August 2017

language of work or name

English

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publication date

18 March 2013

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28 August 2017

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28 August 2017

33

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28 August 2017

10

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28 August 2017

1207-1217

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https://scigraph.springernature.com/pub.10.1038/onc.2013.87

28 August 2017

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Chromatin modifications and their function

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https://api.crossref.org/works/10.1038%2FONC.2013.87

Translating the Histone Code

21 January 2018

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Cancer epigenomics: DNA methylomes and histone-modification maps

21 January 2018

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Covalent modifications of histones during development and disease pathogenesis

21 January 2018

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The complex language of chromatin regulation during transcription

21 January 2018

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Facultative heterochromatin: is there a distinctive molecular signature?

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.87

Selective anchoring of TFIID to nucleosomes by trimethylation of histone H3 lysine 4

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.87

Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.87

Histone methyltransferases in cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.87

Molecular mechanisms of leukemogenesis mediated by MLL fusion proteins

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.87

MLL translocations, histone modifications and leukaemia stem-cell development

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.87

The Mll partial tandem duplication: differential, tissue-specific activity in the presence or absence of the wild-type allele

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Mll partial tandem duplication induces aberrant Hox expression in vivo via specific epigenetic alterations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

DNA hypermethylation and epigenetic silencing of the tumor suppressor gene, SLC5A8, in acute myeloid leukemia with the MLL partial tandem duplication

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

The genetic landscape of the childhood cancer medulloblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Expression of enhancer of zeste homologue 2 is significantly associated with increased tumor cell proliferation and is a marker of aggressive breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

The gene for polycomb group protein enhancer of zeste homolog 2 (EZH2) is amplified in late-stage prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

The polycomb group protein EZH2 is involved in progression of prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breast

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Coexpression of BMI-1 and EZH2 polycomb-group proteins is associated with cycling cells and degree of malignancy in B-cell non-Hodgkin lymphoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

MYC stimulates EZH2 expression by repression of its negative regulator miR-26a

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Enhancer of zeste homolog 2 downregulates E-cadherin by mediating histone H3 methylation in gastric cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Alterations of DNA methylation and histone modifications contribute to gene silencing in hepatocellular carcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

A novel gene, NSD1, is fused to NUP98 in the t(5;11)(q35;p15.5) in de novo childhood acute myeloid leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Genotype-phenotype associations in Sotos syndrome: an analysis of 266 individuals with NSD1 aberrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Epigenetic inactivation of the Sotos overgrowth syndrome gene histone methyltransferase NSD1 in human neuroblastoma and glioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

The histone methyltransferase and putative oncoprotein MMSET is overexpressed in a large variety of human tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Frequent translocation t(4;14)(p16.3;q32.3) in multiple myeloma is associated with increased expression and activating mutations of fibroblast growth factor receptor 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

NUP98 is fused to the NSD3 gene in acute myeloid leukemia associated with t(8;11)(p11.2;p15).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

NSD3, a new SET domain-containing gene, maps to 8p12 and is amplified in human breast cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Histone methyltransferase gene SETD2 is a novel tumor suppressor gene in clear cell renal cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Enhanced SMYD3 expression is essential for the growth of breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Identification of Smyd4 as a potential tumor suppressor gene involved in breast cancer development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Histone lysine methyltransferase SETD8 promotes carcinogenesis by deregulating PCNA expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

hDOT1L links histone methylation to leukemogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

H3K79 methylation profiles define murine and human MLL-AF4 leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Leukaemic transformation by CALM-AF10 involves upregulation of Hoxa5 by hDOT1L

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Mutational analysis of PRDM1 indicates a tumor-suppressor role in diffuse large B-cell lymphomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Inactivation of the PRDM1/BLIMP1 gene in diffuse large B cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

MicroRNA-mediated down-regulation of PRDM1/Blimp-1 in Hodgkin/Reed-Sternberg cells: a potential pathogenetic lesion in Hodgkin lymphomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Candidate tumor suppressor RIZ is frequently involved in colorectal carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Tumor formation and inactivation of RIZ1, an Rb-binding member of a nuclear protein-methyltransferase superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Frequent epigenetic inactivation of RIZ1 by promoter hypermethylation in human gastric carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Biallelic inactivation of the RIZ1 gene in human gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Decreased RIZ1 expression but not RIZ2 in hepatoma and suppression of hepatoma tumorigenicity by RIZ1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

PRDM5 is silenced in human cancers and has growth suppressive activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

PRDM5 identified as a target of epigenetic silencing in colorectal and gastric cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Gene amplification and overexpression of PRDM14 in breast cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

A role for the MLL fusion partner ENL in transcriptional elongation and chromatin modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Global reduction of the epigenetic H3K79 methylation mark and increased chromosomal instability in CALM-AF10-positive leukemias.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

NSD1 mutations are the major cause of Sotos syndrome and occur in some cases of Weaver syndrome but are rare in other overgrowth phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Haploinsufficiency of NSD1 causes Sotos syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

The MMSET histone methyl transferase switches global histone methylation and alters gene expression in t(4;14) multiple myeloma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

The telomerase reverse transcriptase (hTERT) gene is a direct target of the histone methyltransferase SMYD3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Requirement of histone methyltransferase SMYD3 for estrogen receptor-mediated transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

SMYD3 promotes cancer invasion by epigenetic upregulation of the metalloproteinase MMP-9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Overexpression of SMYD2 relates to tumor cell proliferation and malignant outcome of esophageal squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Identification and characterization of Smyd2: a split SET/MYND domain-containing histone H3 lysine 36-specific methyltransferase that interacts with the Sin3 histone deacetylase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

The tale of two domains: proteomics and genomics analysis of SMYD2, a new histone methyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

PR-Set7 is a nucleosome-specific methyltransferase that modifies lysine 20 of histone H4 and is associated with silent chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Mitotic-specific methylation of histone H4 Lys 20 follows increased PR-Set7 expression and its localization to mitotic chromosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Regulation of the histone H4 monomethylase PR-Set7 by CRL4(Cdt2)-mediated PCNA-dependent degradation during DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Monomethylation of histone H4-lysine 20 is involved in chromosome structure and stability and is essential for mouse development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

The role of PR-Set7 in replication licensing depends on Suv4-20h

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Dynamic regulation of the PR-Set7 histone methyltransferase is required for normal cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

SET8 promotes epithelial-mesenchymal transition and confers TWIST dual transcriptional activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Step-wise methylation of histone H3K9 positions heterochromatin at the nuclear periphery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

The polycomb-group gene Ezh2 is required for early mouse development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

The gene encoding the prostatic tumor suppressor PSP94 is a target for repression by the Polycomb group protein EZH2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Integrative genomics analysis reveals silencing of beta-adrenergic signaling by polycomb in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Histone methyltransferase EZH2 induces Akt-dependent genomic instability and BRCA1 inhibition in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Repression of E-cadherin by the polycomb group protein EZH2 in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Context-specific regulation of NF-κB target gene expression by EZH2 in breast cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb-independent

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Characterization of the EZH2-MMSET histone methyltransferase regulatory axis in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Histone demethylases in development and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Lysine-specific demethylase 1 (LSD1) is highly expressed in ER-negative breast cancers and a biomarker predicting aggressive biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Androgen receptor coactivators lysine-specific histone demethylase 1 and four and a half LIM domain protein 2 predict risk of prostate cancer recurrence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Lysine-specific demethylase 1 is strongly expressed in poorly differentiated neuroblastoma: implications for therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

H3K4 dimethylation in hepatocellular carcinoma is rare compared with other hepatobiliary and gastrointestinal carcinomas and correlates with expression of the methylase Ash2 and the demethylase LSD1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

JHDM1B/FBXL10 is a nucleolar protein that represses transcription of ribosomal RNA genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

KDM2A represses transcription of centromeric satellite repeats and maintains the heterochromatic state

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Members of a family of JmjC domain-containing oncoproteins immortalize embryonic fibroblasts via a JmjC domain-dependent process

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

The JmjC domain-containing histone demethylase KDM3A is a positive regulator of the G1/S transition in cancer cells via transcriptional regulation of the HOXA1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Histone demethylase JMJD2B is required for tumor cell proliferation and survival and is overexpressed in gastric cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Cooperative epigenetic modulation by cancer amplicon genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Comprehensive genomic analysis of desmoplastic medulloblastomas: identification of novel amplified genes and separate evaluation of the different histological components

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

The histone demethylase RBP2 Is overexpressed in gastric cancer and its inhibition triggers senescence of cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

JARID1B is a histone H3 lysine 4 demethylase up-regulated in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

A novel gene (PLU-1) containing highly conserved putative DNA/chromatin binding motifs is specifically up-regulated in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

The von Hippel-Lindau tumor suppressor protein regulates gene expression and tumor growth through histone demethylase JARID1C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

JMJD3 is a histone H3K27 demethylase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

The H3K27me3 demethylase, KDM6B, is induced by Epstein-Barr virus and over-expressed in Hodgkin's Lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Histone demethylation mediated by the nuclear amine oxidase homolog LSD1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Cooperative demethylation by JMJD2C and LSD1 promotes androgen receptor-dependent gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Role of androgen receptor and associated lysine-demethylase coregulators, LSD1 and JMJD2A, in localized and advanced human bladder cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Lysine-specific histone demethylase 1 inhibitors control breast cancer proliferation in ERα-dependent and -independent manners.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

The SNAG domain of Snail1 functions as a molecular hook for recruiting lysine-specific demethylase 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Binding of the JmjC demethylase JARID1B to LSD1/NuRD suppresses angiogenesis and metastasis in breast cancer cells by repressing chemokine CCL14.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

The H3K36 demethylase Jhdm1b/Kdm2b regulates cell proliferation and senescence through p15(Ink4b)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Ndy1/KDM2B immortalizes mouse embryonic fibroblasts by repressing the Ink4a/Arf locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Human papillomavirus E7 oncoprotein induces KDM6A and KDM6B histone demethylase expression and causes epigenetic reprogramming

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Gene-specific modulation of TAF10 function by SET9-mediated methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Methylation-acetylation interplay activates p53 in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Regulation of p53 activity through lysine methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Functional interplay between acetylation and methylation of the RelA subunit of NF-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Negative regulation of NF-kappaB action by Set9-mediated lysine methylation of the RelA subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Regulation of NF-kappaB activity through lysine monomethylation of p65.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Reversible methylation of promoter-bound STAT3 by histone-modifying enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Lysine methylation regulates E2F1-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Lysine methylation regulates the pRb tumour suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Interplay between lysine methylation and Cdk phosphorylation in growth control by the retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Regulation of Estrogen Receptor α by the SET7 Lysine Methyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Regulation of the androgen receptor by SET9-mediated methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Lysine methylation and functional modulation of androgen receptor by Set9 methyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

A methylation and phosphorylation switch between an adjacent lysine and serine determines human DNMT1 stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Regulation of DNMT1 stability through SET7-mediated lysine methylation in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Methyltransferase Set7/9 regulates p53 activity by interacting with Sirtuin 1 (SIRT1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Lysine methylation of FOXO3 regulates oxidative stress-induced neuronal cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Methylation by Set9 modulates FoxO3 stability and transcriptional activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Modulation of p53 function by SET8-mediated methylation at lysine 382

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Repression of p53 activity by Smyd2-mediated methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Methylation of the retinoblastoma tumor suppressor by SMYD2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Regulation of NF-kappaB by NSD1/FBXL11-dependent reversible lysine methylation of p65.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Lysine methyltransferase G9a methylates the transcription factor MyoD and regulates skeletal muscle differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

G9a-mediated lysine methylation alters the function of CCAAT/enhancer-binding protein-beta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Methylation of a histone mimic within the histone methyltransferase G9a regulates protein complex assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

G9a and Glp methylate lysine 373 in the tumor suppressor p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

ncRNA- and Pc2 methylation-dependent gene relocation between nuclear structures mediates gene activation programs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

EZH2 generates a methyl degron that is recognized by the DCAF1/DDB1/CUL4 E3 ubiquitin ligase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Role for 53BP1 Tudor domain recognition of p53 dimethylated at lysine 382 in DNA damage signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

p53 is regulated by the lysine demethylase LSD1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

SET domains of histone methyltransferases recognize ISWI-remodeled nucleosomal species.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Quantitative PCR identifies a minimal deleted region of 120 kb extending from the Philadelphia chromosome ABL translocation breakpoint in chronic myeloid leukemia with poor outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Frequency of NUP98-NSD1 fusion transcript in childhood acute myeloid leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

MMSET is overexpressed in cancers: link with tumor aggressiveness

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Gene expression profiling in hepatocellular carcinoma: upregulation of genes in amplified chromosome regions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Recurrent Inactivation of the PRDM1 Gene in Primary Central Nervous System Lymphoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

A potential role for PRDM12 in the pathogenesis of chronic myeloid leukaemia with derivative chromosome 9 deletion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Molecular cytogenetic characterization of a metastatic lung sarcomatoid carcinoma: 9p23 neocentromere and 9p23-p24 amplification including JAK2 and JMJD2C

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

Cross-talk between post-translational modifications regulates life or death decisions by E2F1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.87

31 March 2020

Identifiers

DOI

10.1038/ONC.2013.87

1 reference

PubMed ID

23503463

Dimensions Publication ID

28 August 2017

0 references

1 reference

PubMed ID

23503463