(Q38090663)

28 August 2017

title

Small-molecule inhibitors binding to protein kinases. Part I: exceptions from the traditional pharmacophore approach of type I inhibition (English)

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28 August 2017

Ac Backes

1

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28 August 2017

B Zech

2

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28 August 2017

B Felber

3

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28 August 2017

B Klebl

4

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28 August 2017

G Müller

5

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28 August 2017

language of work or name

English

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publication date

1 December 2008

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Expert Opinion on Drug Discovery

28 August 2017

published in

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28 August 2017

volume

3

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28 August 2017

issue

12

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28 August 2017

page(s)

1409-1425

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Molecular recognition of protein kinase binding pockets for design of potent and selective kinase inhibitors

28 August 2017

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Oncogenic kinase signalling

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Protein kinases--the major drug targets of the twenty-first century?

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Angiogenesis: an organizing principle for drug discovery?

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Regulation of protein kinases; controlling activity through activation segment conformation

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The conformational plasticity of protein kinases

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Active and inactive protein kinases: structural basis for regulation

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Regulation of the c-Abl and Bcr-Abl tyrosine kinases

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Living with or without cyclins and cyclin-dependent kinases

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Strategies toward the design of novel and selective protein tyrosine kinase inhibitors

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Inhibitors of epidermal growth factor receptor tyrosine kinase: Novel C-5 substituted anilinoquinazolines designed to target the ribose pocket

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Inhibition of drug-resistant mutants of ABL, KIT, and EGF receptor kinases

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Structures of Lung Cancer-Derived EGFR Mutants and Inhibitor Complexes: Mechanism of Activation and Insights into Differential Inhibitor Sensitivity

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Structural basis for p38alpha MAP kinase quinazolinone and pyridol-pyrimidine inhibitor specificity

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Biphenyl amide p38 kinase inhibitors 2: Optimisation and SAR.

21 January 2018

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Biphenyl amide p38 kinase inhibitors 1: Discovery and binding mode

21 January 2018

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Inhibition of cyclin-dependent kinases, GSK-3beta and CK1 by hymenialdisine, a marine sponge constituent

21 January 2018

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Crystal structures of the phosphorylated and unphosphorylated kinase domains of the Cdc42-associated tyrosine kinase ACK1

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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NMR characterization of kinase p38 dynamics in free and ligand-bound forms

21 January 2018

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10.1517/17460440802579975

21 January 2018

Identifiers

DOI

1 reference

28 August 2017

1 reference