(Q38101493)

28 August 2017

Brain activation of SIRT1: role in neuropathology (English)

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28 August 2017

Alanna Fernandes Paraíso

series ordinal

1

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28 August 2017

Keila Lopes Mendes

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2

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28 August 2017

Sergio Henrique Sousa Santos

series ordinal

3

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28 August 2017

25 April 2013

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28 August 2017

Molecular Neurobiology

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28 August 2017

48

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28 August 2017

3

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28 August 2017

681-689

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https://scigraph.springernature.com/pub.10.1007/s12035-013-8459-x

28 August 2017

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cites work

The neurobiology of sirtuins and their role in neurodegeneration

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Dietary polyphenols as modulators of brain functions: biological actions and molecular mechanisms underpinning their beneficial effects

21 January 2018

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Potential role of sirtuin as a therapeutic target for neurodegenerative diseases

21 January 2018

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Resveratrol as a therapeutic agent for neurodegenerative diseases

21 January 2018

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Transgenic models of Alzheimer's disease: learning from animals

21 January 2018

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Neuronal protection by sirtuins in Alzheimer's disease

21 January 2018

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Neuronal death and survival under oxidative stress in Alzheimer and Parkinson diseases

21 January 2018

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Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins

21 January 2018

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Sirtuins in mammals: insights into their biological function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Distribution analysis of deacetylase SIRT1 in rodent and human nervous systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Mammalian Sirt1: insights on its biological functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

21 January 2018

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Predominant expression of Sir2alpha, an NAD-dependent histone deacetylase, in the embryonic mouse heart and brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Circadian rhythms and memory formation: regulation by chromatin remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Histone deacetylase SIRT1 modulates neuronal differentiation by its nuclear translocation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Brain SIRT1: anatomical distribution and regulation by energy availability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Beyond transcription factors: the role of chromatin modifying enzymes in regulating transcription required for memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Cognitive neuroepigenetics: a role for epigenetic mechanisms in learning and memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Paths of convergence: sirtuins in aging and neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

SirT1 inhibition reduces IGF-I/IRS-2/Ras/ERK1/2 signaling and protects neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Melatonin preserves longevity protein (sirtuin 1) expression in the hippocampus of total sleep-deprived rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Negative control of p53 by Sir2alpha promotes cell survival under stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1{alpha}

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

SIRT1 deacetylates and positively regulates the nuclear receptor LXR

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

SIRT1 overexpression antagonizes cellular senescence with activated ERK/S6k1 signaling in human diploid fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

The direct involvement of SirT1 in insulin-induced insulin receptor substrate-2 tyrosine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Gene regulation and DNA damage in the ageing human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Reciprocal regulation of inflammation and lipid metabolism by liver X receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Expression of Liver X Receptor Target Genes Decreases Cellular Amyloid β Peptide Secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Attenuation of neuroinflammation and Alzheimer's disease pathology by liver x receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Redox regulation of NF-kappaB activation: distinct redox regulation between the cytoplasm and the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Roles for NF-kappaB in nerve cell survival, plasticity, and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Genomic profiling of short- and long-term caloric restriction effects in the liver of aging mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Neuroprotective and neurorestorative signal transduction mechanisms in brain aging: modification by genes, diet and behavior.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Modulation of neurodegeneration by molecular chaperones

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Neurodegenerative diseases: Lessons from genome-wide screens in small model organisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

A beta oligomers - a decade of discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Mitochondria, oxidants, and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Mitochondria take center stage in aging and neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

The alpha-ketoglutarate-dehydrogenase complex: a mediator between mitochondria and oxidative stress in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Molecular and cellular basis for anti-amyloid therapy in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Deciphering the genetic basis of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

ADAM proteases: protective role in Alzheimer's and prion diseases?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Constitutive and regulated alpha-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

beta-Amyloid peptide free radical fragments initiate synaptosomal lipoperoxidation in a sequence-specific fashion: implications to Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Cu(II) potentiation of alzheimer abeta neurotoxicity. Correlation with cell-free hydrogen peroxide production and metal reduction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Immunotherapeutic Approaches to Alzheimer's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Caloric restriction attenuates Abeta-deposition in Alzheimer transgenic models

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

NF-kappaB pathway: a target for preventing beta-amyloid (Abeta)-induced neuronal damage and Abeta42 production

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Will caloric restriction and folate protect against AD and PD?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Protection from Alzheimer's-like disease in the mouse by genetic ablation of inducible nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

SIRT1 suppresses beta-amyloid production by activating the alpha-secretase gene ADAM10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Active regulator of SIRT1 cooperates with SIRT1 and facilitates suppression of p53 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Acetylation of tau inhibits its degradation and contributes to tauopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Parkinson's disease and α-synuclein expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

SIRT1 protects against α-synuclein aggregation by activating molecular chaperones

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

The SIRT1 activator resveratrol protects SK-N-BE cells from oxidative stress and against toxicity caused by alpha-synuclein or amyloid-beta (1-42) peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Sirtuins in neurodegenerative diseases: a biological-chemical perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

PGC-1{alpha} and PGC-1{beta} regulate mitochondrial density in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Dietary oxyresveratrol prevents parkinsonian mimetic 6-hydroxydopamine neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Resveratrol protects dopaminergic neurons in midbrain slice culture from multiple insults.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

The clinical syndrome of striatal dopamine deficiency. Parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Chronic, low-dose rotenone reproduces Lewy neurites found in early stages of Parkinson's disease, reduces mitochondrial movement and slowly kills differentiated SH-SY5Y neural cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Pesticides and impairment of mitochondrial function in relation with the parkinsonian syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Modulation of sirtuins: new targets for antiageing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Diseases of unstable repeat expansion: mechanisms and common principles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

After the grape rush: sirtuins as epigenetic drug targets in neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Huntington's disease: from huntingtin function and dysfunction to therapeutic strategies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

SIRT1 and neuronal diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

A Ufd2/D4Cole1e chimeric protein and overexpression of Rbp7 in the slow Wallerian degeneration (WldS) mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Wallerian degeneration of injured axons and synapses is delayed by a Ube4b/Nmnat chimeric gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

SIRT1-dependent regulation of chromatin and transcription: linking NAD(+) metabolism and signaling to the control of cellular functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Pathways for ischemic cytoprotection: role of sirtuins in caloric restriction, resveratrol, and ischemic preconditioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Resveratrol mimics ischemic preconditioning in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Peroxisome Proliferator-Activated Receptor-gamma in Amyotrophic Lateral Sclerosis and Huntington's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Sirtuins for healthy neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Erratum: Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8459-X

Problems of cell death in neurodegeneration and Alzheimer's Disease.

21 January 2018

1 reference

12 December 2020

The Sirt1 deacetylase modulates the insulin-like growth factor signaling pathway in mammals

1 reference

12 December 2020

Calorie restriction attenuates Alzheimer's disease type brain amyloidosis in Squirrel monkeys (Saimiri sciureus).

1 reference

12 December 2020

Four genes responsible for a position effect on expression from HML and HMR in Saccharomyces cerevisiae

1 reference

12 December 2020

Joining the dots: from chromatin remodeling to neuronal plasticity

1 reference

12 December 2020

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

1 reference

12 December 2020

A review of the sirtuin system, its clinical implications, and the potential role of dietary activators like resveratrol: part 2.

1 reference

12 December 2020

A review of the sirtuin system, its clinical implications, and the potential role of dietary activators like resveratrol: part 1.

1 reference

12 December 2020

Genetic analysis of SIRT1 gene promoter in sporadic Parkinson's disease

1 reference

12 December 2020

Mutated recombinant human glucagon-like peptide-1 protects SH-SY5Y cells from apoptosis induced by amyloid-beta peptide (1-42).

1 reference

12 December 2020

Protective effects and mechanisms of sirtuins in the nervous system

1 reference

12 December 2020

Caloric restriction attenuates beta-amyloid neuropathology in a mouse model of Alzheimer's disease

1 reference

12 December 2020

The free radical theory of aging matures

1 reference

12 December 2020

Neuroscience. NAD to the rescue

1 reference

12 December 2020

Crosstalk between p53 and FOXO transcription factors

1 reference

12 December 2020

Amyloid beta-peptide is produced by cultured cells during normal metabolism: a reprise.

1 reference

12 December 2020

The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases

1 reference

12 December 2020

Translating cell survival and cell longevity into treatment strategies with SIRT1

1 reference

12 December 2020

Dietary restriction and 2-deoxyglucose administration improve behavioral outcome and reduce degeneration of dopaminergic neurons in models of Parkinson's disease.

1 reference

12 December 2020

Alzheimer's disease results from the cerebral accumulation and cytotoxicity of amyloid beta-protein

1 reference

12 December 2020

10.1007/S12035-013-8459-X

Identifiers

DOI

1 reference

Dimensions Publication ID

28 August 2017

0 references

1 reference