(Q38113212)

29 August 2017

title

The role of NDRG1 in the pathology and potential treatment of human cancers (English)

1 reference

29 August 2017

0 references

4

1 reference

29 August 2017

5

1 reference

29 August 2017

8

1 reference

29 August 2017

Dong-Hun Bae

1

0 references

Michael Huang

object named as

Michael L Huang

series ordinal

3

0 references

Sumit Sahni

object named as

Sumit Sahni

series ordinal

7

0 references

Patric J Jansson

series ordinal

2

object named as

Patric J Jansson

1 reference

29 August 2017

C Soon Lee

6

1 reference

29 August 2017

language of work or name

English

0 references

publication date

8 June 2013

1 reference

Journal of Clinical Pathology

29 August 2017

published in

1 reference

29 August 2017

volume

66

1 reference

29 August 2017

issue

11

1 reference

29 August 2017

page(s)

911-917

1 reference

The metastasis suppressor, Ndrg-1: a new ally in the fight against cancer

29 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

Drg1 expression in 131 colorectal liver metastases: correlation with clinical variables and patient outcomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

NDRG1, a growth and cancer related gene: regulation of gene expression and function in normal and disease states

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

Expression of N-myc downstream regulated gene 1 (NDRG1) in central neurocytoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

The iron-regulated metastasis suppressor, Ndrg-1: identification of novel molecular targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

Identification of NDRG1-regulated genes associated with invasive potential in cervical and ovarian cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

Nitric oxide suppresses tumor cell migration through N-Myc downstream-regulated gene-1 (NDRG1) expression: role of chelatable iron

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

NDRG1 is down-regulated in the early apoptotic event induced by camptothecin analogs: the potential role in proteolytic activation of PKC delta and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

The tumor metastasis suppressor gene Drg-1 down-regulates the expression of activating transcription factor 3 in prostate cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

A conserved Myc protein domain, MBIV, regulates DNA binding, apoptosis, transformation, and G2 arrest.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

A conserved element in Myc that negatively regulates its proapoptotic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

The myc oncogene: MarvelouslY Complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

NDRG1 and CRK-I/II are regulators of endothelial cell migration under Intermittent Hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

Hypoxia upregulates the expression of the NDRG1 gene leading to its overexpression in various human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

Expression of NDRG1, a differentiation-related gene, in human tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

NDRG1 contributes to retinoic acid-induced differentiation of leukemic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

Cap43/NDRG1/Drg-1 is a molecular target for angiogenesis and a prognostic indicator in cervical adenocarcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

The iron-regulated metastasis suppressor NDRG1 targets NEDD4L, PTEN, and SMAD4 and inhibits the PI3K and Ras signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

Hypoxia and retinoic acid-inducible NDRG1 expression is responsible for doxorubicin and retinoic acid resistance in hepatocellular carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

The growth-inhibitory Ndrg1 gene is a Myc negative target in human neuroblastomas and other cell types with overexpressed N- or c-myc

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

N-myc downstream regulated gene 1 modulates Wnt-β-catenin signalling and pleiotropically suppresses metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

N-myc downstream regulated gene1/Cap43 overexpression suppresses tumor growth by hepatic cancer cells through cell cycle arrest at the G0/G1 phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

Identification of differentially expressed genes in oral squamous cell carcinoma (OSCC): overexpression of NPM, CDK1 and NDRG1 and underexpression of CHES1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

The metastasis suppressor, N-myc downstream regulated gene 1 (NDRG1), upregulates p21 via p53-independent mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

Function of Drg1/Rit42 in p53-dependent mitotic spindle checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

17Beta-estradiol induces down-regulation of Cap43/NDRG1/Drg-1, a putative differentiation-related and metastasis suppressor gene, in human breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

Phosphorylation of NDRG1 is temporally and spatially controlled during the cell cycle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

The iron chelators Dp44mT and DFO inhibit TGF-β-induced epithelial-mesenchymal transition via up-regulation of N-Myc downstream-regulated gene 1 (NDRG1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

NDRG1 is necessary for p53-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

p53-dependent NDRG1 expression induces inhibition of intestinal epithelial cell proliferation but not apoptosis after polyamine depletion

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

N-myc downstream regulated 1 (NDRG1) is regulated by eukaryotic initiation factor 3a (eIF3a) during cellular stress caused by iron depletion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

Egr-1 mediates hypoxia-inducible transcription of the NDRG1 gene through an overlapping Egr-1/Sp1 binding site in the promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

Reactive oxygen species: a breath of life or death?

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

Hypoxia-induced autophagy: cell death or cell survival?

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

Altered N-myc downstream-regulated gene 1 protein expression in African-American compared with caucasian prostate cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

Iron chelators with high antiproliferative activity up-regulate the expression of a growth inhibitory and metastasis suppressor gene: a link between iron metabolism and proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

Hypoxia induces the expression of a 43-kDa protein (PROXY-1) in normal and malignant cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

Stress granules: sites of mRNA triage that regulate mRNA stability and translatability

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

Stress granules: the Tao of RNA triage

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

Role of the putative tumor metastasis suppressor gene Drg-1 in breast cancer progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

Overexpression of Cap43 gene in supraglottic laryngeal squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

T-box 2 represses NDRG1 through an EGR1-dependent mechanism to drive the proliferation of breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

Novel thiosemicarbazone iron chelators induce up-regulation and phosphorylation of the metastasis suppressor N-myc down-stream regulated gene 1: a new strategy for the treatment of pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

N-myc-dependent repression of ndr1, a gene identified by direct subtraction of whole mouse embryo cDNAs between wild type and N-myc mutant

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

L-Mimosine blocks cell proliferation via upregulation of B-cell translocation gene 2 and N-myc downstream regulated gene 1 in prostate carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

N-myc downstream regulated gene-1/Cap43 may play an important role in malignant progression of prostate cancer, in its close association with E-cadherin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

Transcriptional silencing of N-Myc downstream-regulated gene 1 (NDRG1) in metastatic colon cancer cell line SW620.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

Tumor growth suppression in pancreatic cancer by a putative metastasis suppressor gene Cap43/NDRG1/Drg-1 through modulation of angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

Down-regulation of NDRG1 promotes migration of cancer cells during reoxygenation

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

A novel molecular marker for early detection and evaluating prognosis of gastric cancer: N-myc downstream regulated gene-1 (NDRG1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

Identification of high-risk stage II colorectal tumors by combined analysis of the NDRG1 gene expression and the depth of tumor invasion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

KAI1 gene is engaged in NDRG1 gene-mediated metastasis suppression through the ATF3-NFkappaB complex in human prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

Actin structure and function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

Role of RhoA and its effectors ROCK and mDia1 in the modulation of deformation-induced FAK, ERK, p38, and MLC motogenic signals in human Caco-2 intestinal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

Targeting the metastasis suppressor, NDRG1, using novel iron chelators: regulation of stress fiber-mediated tumor cell migration via modulation of the ROCK1/pMLC2 signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

Downregulation of NDRG1 promotes invasion of human gastric cancer AGS cells through MMP-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

N-myc downstream regulated gene 1/Cap43 suppresses tumor growth and angiogenesis of pancreatic cancer through attenuation of inhibitor of kappaB kinase beta expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

Tumor-cell death, autophagy, and immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

N-myc downstream regulated gene-1 expression correlates with reduced pancreatic cancer growth and increased apoptosis in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

Bp44mT: an orally active iron chelator of the thiosemicarbazone class with potent anti-tumour efficacy

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

Novel second-generation di-2-pyridylketone thiosemicarbazones show synergism with standard chemotherapeutics and demonstrate potent activity against lung cancer xenografts after oral and intravenous administration in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

Novel di-2-pyridyl-derived iron chelators with marked and selective antitumor activity: in vitro and in vivo assessment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

Antitumor activity of metal-chelating compound Dp44mT is mediated by formation of a redox-active copper complex that accumulates in lysosomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

The evolution of iron chelators for the treatment of iron overload disease and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

The uptake of iron and transferrin by the human malignant melanoma cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

Tuning cell cycle regulation with an iron key.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

Modulation of Wnt/β-catenin signaling and proliferation by a ferrous iron chelator with therapeutic efficacy in genetically engineered mouse models of cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

Dual Role of Mitochondrial Reactive Oxygen Species in Hypoxia Signaling: Activation of Nuclear Factor- B via c-SRC and Oxidant-Dependent Cell Death

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FJCLINPATH-2013-201692

10.1136/JCLINPATH-2013-201692

21 January 2018

Identifiers

DOI

1 reference

29 August 2017

1 reference