(Q38146987)

29 August 2017

title

Genetics and the molecular pathogenesis of pulmonary arterial hypertension (English)

1 reference

29 August 2017

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Nicholas W Morrell

2

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author name string

Dong Liu

series ordinal

1

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29 August 2017

publication date

1 December 2013

1 reference

Current Hypertension Reports

29 August 2017

published in

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29 August 2017

volume

15

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29 August 2017

issue

6

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29 August 2017

page(s)

632-637

1 reference

https://scigraph.springernature.com/pub.10.1007/s11906-013-0393-9

29 August 2017

exact match

0 references

cites work

Primary pulmonary hypertension. A national prospective study

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

Monoclonal endothelial cell proliferation is present in primary but not secondary pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

Heterozygous germline mutations in BMPR2, encoding a TGF-beta receptor, cause familial primary pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

BMPR2 mutations found in Japanese patients with familial and sporadic primary pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

Sporadic primary pulmonary hypertension is associated with germline mutations of the gene encoding BMPR-II, a receptor member of the TGF-beta family

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

High frequency of BMPR2 exonic deletions/duplications in familial pulmonary arterial hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

BMPR2 gene rearrangements account for a significant proportion of mutations in familial and idiopathic pulmonary arterial hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

p38 mitogen-activated protein kinase can be involved in transforming growth factor beta superfamily signal transduction in Drosophila wing morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

Molecular genetics and clinical features of Chinese idiopathic and heritable pulmonary arterial hypertension patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

Bone morphogenetic protein receptor type 2 mutations, clinical phenotypes and outcomes of Japanese patients with sporadic or familial pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

Pulmonary arterial hypertension: baseline characteristics from the REVEAL Registry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

Survival in patients with idiopathic, familial, and anorexigen-associated pulmonary arterial hypertension in the modern management era.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

Clinical outcomes of pulmonary arterial hypertension in carriers of BMPR2 mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

BMPR2 mutations influence phenotype more obviously in male patients with pulmonary arterial hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

Absence of influence of gender and BMPR2 mutation type on clinical phenotypes of pulmonary arterial hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

Truncating and missense BMPR2 mutations differentially affect the severity of heritable pulmonary arterial hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

Molecular genetic characterization of SMAD signaling molecules in pulmonary arterial hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

TBX4 mutations (small patella syndrome) are associated with childhood-onset pulmonary arterial hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

Loss-of-function thrombospondin-1 mutations in familial pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

Genome-wide association analysis identifies a susceptibility locus for pulmonary arterial hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

Alterations in oestrogen metabolism: implications for higher penetrance of familial pulmonary arterial hypertension in females

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

Gene expression in BMPR2 mutation carriers with and without evidence of pulmonary arterial hypertension suggests pathways relevant to disease penetrance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

Penetrance of pulmonary arterial hypertension is modulated by the expression of normal BMPR2 allele

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

Role of BMPR2 alternative splicing in heritable pulmonary arterial hypertension penetrance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

Connectivity map analysis of nonsense-mediated decay-positive BMPR2-related hereditary pulmonary arterial hypertension provides insights into disease penetrance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

Somatic chromosome abnormalities in the lungs of patients with pulmonary arterial hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

The transforming growth factor-β-bone morphogenetic protein type signalling pathway in pulmonary vascular homeostasis and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

SMAD1 deficiency in either endothelial or smooth muscle cells can predispose mice to pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

BMPR-II deficiency elicits pro-proliferative and anti-apoptotic responses through the activation of TGFβ-TAK1-MAPK pathways in PAH

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

Inhibition of overactive transforming growth factor-β signaling by prostacyclin analogs in pulmonary arterial hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

Smad-dependent and smad-independent induction of id1 by prostacyclin analogues inhibits proliferation of pulmonary artery smooth muscle cells in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

Bone morphogenetic protein signaling in vascular disease: anti-inflammatory action through myocardin-related transcription factor A

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

BMP type II receptor deficiency confers resistance to growth inhibition by TGF-β in pulmonary artery smooth muscle cells: role of proinflammatory cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

Bone morphogenetic protein receptor II regulates pulmonary artery endothelial cell barrier function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

Attenuation of leukocyte recruitment via CXCR1/2 inhibition stops the progression of PAH in mice with genetic ablation of endothelial BMPR-II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

Evidence of dysfunction of endothelial progenitors in pulmonary arterial hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

Elevated Levels of Inflammatory Cytokines Predict Survival in Idiopathic and Familial Pulmonary Arterial Hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

ALK2 and BMPR2 knockdown and endothelin-1 production by pulmonary microvascular endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

Sildenafil potentiates bone morphogenetic protein signaling in pulmonary arterial smooth muscle cells and in experimental pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

Epigenetic attenuation of mitochondrial superoxide dismutase 2 in pulmonary arterial hypertension: a basis for excessive cell proliferation and a new therapeutic target.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

Critical role for the advanced glycation end-products receptor in pulmonary arterial hypertension etiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

Altered MicroRNA processing in heritable pulmonary arterial hypertension: an important role for Smad-8

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

Targeted gene delivery of BMPR2 attenuates pulmonary hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

Bone morphogenetic protein type 2 receptor gene therapy attenuates hypoxic pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

Overexpression of human bone morphogenetic protein receptor 2 does not ameliorate monocrotaline pulmonary arterial hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

TGFβ receptor gene variants in systemic sclerosis-related pulmonary arterial hypertension: results from a multicentre EUSTAR study of European Caucasian patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-013-0393-9

A Role for miR-145 in Pulmonary Arterial Hypertension

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24078385

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Relationship of BMPR2 mutations to vasoreactivity in pulmonary arterial hypertension

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24078385

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Dexamethasone reverses monocrotaline-induced pulmonary arterial hypertension in rats

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24078385

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S11906-013-0393-9

1 reference

Dimensions Publication ID

29 August 2017

1032586961

0 references

1 reference