(Q38151850)

29 August 2017

title

The actin-driven spatiotemporal organization of T-cell signaling at the system scale (English)

1 reference

29 August 2017

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24117818%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

author name string

Kole T Roybal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24117818%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Parisa Sinai

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24117818%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Robert F Murphy

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24117818%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Christoph Wülfing

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24117818%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

language of work or name

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1 November 2013

1 reference

29 August 2017

published in

Immunological Reviews

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24117818%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

volume

256

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24117818%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24117818%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

page(s)

133-147

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24117818%20AND%20SRC:MED&resulttype=core&format=json

Three-dimensional segregation of supramolecular activation clusters in T cells

1 June 2020

cites work

1 reference

Selective modulation of protein kinase C-theta during T-cell activation

21 January 2018

1 reference

T cell receptor ligation induces the formation of dynamically regulated signaling assemblies

21 January 2018

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Sustained and dynamic inositol lipid metabolism inside and outside the immunological synapse

21 January 2018

1 reference

Single-molecule microscopy reveals plasma membrane microdomains created by protein-protein networks that exclude or trap signaling molecules in T cells

21 January 2018

1 reference

The immunological synapse: a molecular machine controlling T cell activation

21 January 2018

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Differential clustering of CD4 and CD3zeta during T cell recognition

21 January 2018

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T cell receptor signaling precedes immunological synapse formation

21 January 2018

1 reference

The immunological synapse of CTL contains a secretory domain and membrane bridges.

21 January 2018

1 reference

Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76.

21 January 2018

1 reference

Cutting edge: TCR engagement and triggering in the absence of large-scale molecular segregation at the T cell-APC contact site

21 January 2018

1 reference

Complex and dynamic redistribution of NF-kappaB signaling intermediates in response to T cell receptor stimulation

21 January 2018

1 reference

Cytotoxic T lymphocyte antigen-4 accumulation in the immunological synapse is regulated by TCR signal strength

21 January 2018

1 reference

Amoeboid T lymphocytes require the septin cytoskeleton for cortical integrity and persistent motility

21 January 2018

1 reference

Confinement-optimized three-dimensional T cell amoeboid motility is modulated via myosin IIA-regulated adhesions.

21 January 2018

1 reference

Asymmetric T lymphocyte division in the initiation of adaptive immune responses.

21 January 2018

1 reference

Asymmetric cell division of T cells upon antigen presentation uses multiple conserved mechanisms

21 January 2018

1 reference

Coordination of Rho GTPase activities during cell protrusion

21 January 2018

1 reference

Cell shape and negative links in regulatory motifs together control spatial information flow in signaling networks

21 January 2018

1 reference

Counting cytokinesis proteins globally and locally in fission yeast.

21 January 2018

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Automated subcellular location determination and high-throughput microscopy

21 January 2018

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Biological imaging software tools

21 January 2018

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Divergent lymphocyte signalling revealed by a powerful new tool for analysis of time-lapse microscopy.

21 January 2018

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TACTICS, an interactive platform for customized high-content bioimaging analysis

21 January 2018

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Deformation-based nuclear morphometry: capturing nuclear shape variation in HeLa cells

21 January 2018

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CellOrganizer: Image-derived models of subcellular organization and protein distribution

21 January 2018

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Computational modeling of cellular signaling processes embedded into dynamic spatial contexts

21 January 2018

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Spatiotemporal patterning during T cell activation is highly diverse

21 January 2018

1 reference

The distal pole complex: a novel membrane domain distal to the immunological synapse

21 January 2018

1 reference

Mechanisms for segregating T cell receptor and adhesion molecules during immunological synapse formation in Jurkat T cells

21 January 2018

1 reference

Regulation of sustained actin dynamics by the TCR and costimulation as a mechanism of receptor localization

21 January 2018

1 reference

A large T cell invagination with CD2 enrichment resets receptor engagement in the immunological synapse

21 January 2018

1 reference

T cell sensing of antigen dose governs interactive behavior with dendritic cells and sets a threshold for T cell activation

21 January 2018

1 reference

How antigen quantity and quality determine T-cell decisions in lymphoid tissue

21 January 2018

1 reference

Subcellular dynamics of T cell immunological synapses and kinapses in lymph nodes.

21 January 2018

1 reference

Dynamic in situ cytometry uncovers T cell receptor signaling during immunological synapses and kinapses in vivo.

21 January 2018

1 reference

Antigen presentation in extracellular matrix: interactions of T cells with dendritic cells are dynamic, short lived, and sequential

21 January 2018

1 reference

T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster

21 January 2018

1 reference

F-actin polymerization and retrograde flow drive sustained PLCγ1 signaling during T cell activation

21 January 2018

1 reference

Actin retrograde flow and actomyosin II arc contraction drive receptor cluster dynamics at the immunological synapse in Jurkat T cells

21 January 2018

1 reference

T-cell triggering thresholds are modulated by the number of antigen within individual T-cell receptor clusters

21 January 2018

1 reference

The lymphoid lineage-specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cells

21 January 2018

1 reference

Itk controls the spatiotemporal organization of T cell activation

21 January 2018

1 reference

Imaging synapse formation during thymocyte selection: inability of CD3zeta to form a stable central accumulation during negative selection

21 January 2018

1 reference

Low ligand requirement for deletion and lack of synapses in positive selection enforce the gauntlet of thymic T cell maturation

21 January 2018

1 reference

Distinct patterns of membrane microdomain partitioning in Th1 and th2 cells.

21 January 2018

1 reference

Protein kinase C-theta mediates negative feedback on regulatory T cell function

21 January 2018

1 reference

Transience in polarization of cytolytic effectors is required for efficient killing and controlled by Cdc42

21 January 2018

1 reference

Mechanism and function of Vav1 localisation in TCR signalling.

21 January 2018

1 reference

Self-reactive human CD4 T cell clones form unusual immunological synapses

21 January 2018

1 reference

The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T cell receptor transgenic mice

21 January 2018

1 reference

Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells

21 January 2018

1 reference

Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptor

21 January 2018

1 reference

Positive and negative regulation of T-cell activation through kinases and phosphatases

21 January 2018

1 reference

Polarity of T cell shape, motility, and sensitivity to antigen

21 January 2018

1 reference

Ca2+ signals in CD4+ T cells during early contacts with antigen-bearing dendritic cells in lymph node

21 January 2018

1 reference

GRB2-mediated recruitment of THEMIS to LAT is essential for thymocyte development

21 January 2018

1 reference

Staging and resetting T cell activation in SMACs

21 January 2018

1 reference

Dynamic actin polymerization drives T cell receptor-induced spreading: a role for the signal transduction adaptor LAT.

21 January 2018

1 reference

Remodelling of cortical actin where lytic granules dock at natural killer cell immune synapses revealed by super-resolution microscopy

21 January 2018

1 reference

Natural killer cell lytic granule secretion occurs through a pervasive actin network at the immune synapse

21 January 2018

1 reference

Phase transitions in the assembly of multivalent signalling proteins

21 January 2018

1 reference

Controversy and consensus regarding myosin II function at the immunological synapse

21 January 2018

1 reference

Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation

21 January 2018

1 reference

The minimal number of class II MHC-antigen complexes needed for T cell activation

21 January 2018

1 reference

Direct observation of ligand recognition by T cells.

21 January 2018

1 reference

Ligand recognition by alpha beta T cell receptors

21 January 2018

1 reference

How TCRs bind MHCs, peptides, and coreceptors

21 January 2018

1 reference

Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton

21 January 2018

1 reference

A TCR binds to antagonist ligands with lower affinities and faster dissociation rates than to agonists

21 January 2018

1 reference

Characterization of dynamic actin associations with T-cell receptor microclusters in primary T cells.

21 January 2018

1 reference

Kinetic discrimination in T-cell activation

21 January 2018

1 reference

Antigen recognition is facilitated by invadosome-like protrusions formed by memory/effector T cells

21 January 2018

1 reference

CD4+ T-cell synapses involve multiple distinct stages

21 January 2018

1 reference

The size of the synaptic cleft and distinct distributions of filamentous actin, ezrin, CD43, and CD45 at activating and inhibitory human NK cell immune synapses

21 January 2018

1 reference

Membranous structures transfer cell surface proteins across NK cell immune synapses

21 January 2018

1 reference

The strength of T cell receptor signal controls the polarization of cytotoxic machinery to the immunological synapse

21 January 2018

1 reference

Potential for control of signaling pathways via cell size and shape

21 January 2018

1 reference

Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus

21 January 2018

1 reference

Phosphoinositides and membrane curvature switch the mode of actin polymerization via selective recruitment of toca-1 and Snx9

21 January 2018

1 reference

Dynamic interaction of amphiphysin with N-WASP regulates actin assembly

21 January 2018

1 reference

Cdc42-interacting protein-4 functionally links actin and microtubule networks at the cytolytic NK cell immunological synapse.

21 January 2018

1 reference

Sculpting organs: mechanical regulation of tissue development

21 January 2018

1 reference

Forcing stem cells to behave: a biophysical perspective of the cellular microenvironment.

21 January 2018

1 reference

21 January 2018

Metastatic cancer cell

1 reference

Actin-Myosin Contractility Is Responsible for the Reduced Viability of Dissociated Human Embryonic Stem Cells

21 January 2018

1 reference

PIP5KI gamma is required for cardiovascular and neuronal development

21 January 2018

1 reference

HS1 functions as an essential actin-regulatory adaptor protein at the immune synapse

21 January 2018

1 reference

The WAVE2 complex regulates actin cytoskeletal reorganization and CRAC-mediated calcium entry during T cell activation

21 January 2018

1 reference

Role for the Abi/wave protein complex in T cell receptor-mediated proliferation and cytoskeletal remodeling.

21 January 2018

1 reference

Differential roles for Wiskott-Aldrich syndrome protein in immune synapse formation and IL-2 production

21 January 2018

1 reference

Cofilin peptide homologs interfere with immunological synapse formation and T cell activation

21 January 2018

1 reference

Requirement for coronin 1 in T lymphocyte trafficking and cellular homeostasis

21 January 2018

1 reference

Coronin-1A links cytoskeleton dynamics to TCR alpha beta-induced cell signaling

21 January 2018

1 reference

Fyn and PTP-PEST-mediated regulation of Wiskott-Aldrich syndrome protein (WASp) tyrosine phosphorylation is required for coupling T cell antigen receptor engagement to WASp effector function and T cell activation

21 January 2018

1 reference

Wiskott-Aldrich syndrome protein-deficient mice reveal a role for WASP in T but not B cell activation

21 January 2018

1 reference

Integration of the movement of signaling microclusters with cellular motility in immunological synapses.

21 January 2018

1 reference

Kinase-independent functions for Itk in TCR-induced regulation of Vav and the actin cytoskeleton.

21 January 2018

1 reference

Vav-family proteins in T-cell signalling

21 January 2018

1 reference

CD28 engagement promotes actin polymerization through the activation of the small Rho GTPase Cdc42 in human T cells

21 January 2018

1 reference

Specific patterns of Cdc42 activity are related to distinct elements of T cell polarization

21 January 2018

1 reference

T cell receptor (TCR) clustering in the immunological synapse integrates TCR and costimulatory signaling in selected T cells

21 January 2018

1 reference

CD2AP links cortactin and capping protein at the cell periphery to facilitate formation of lamellipodia.

21 January 2018

1 reference

Fluorescence proteins, live-cell imaging, and mechanobiology: seeing is believing

21 January 2018

1 reference

Chromophore-assisted light inactivation (CALI) using the phototoxic fluorescent protein KillerRed.

21 January 2018

1 reference

Spatial and temporal dynamics of T cell receptor signaling with a photoactivatable agonist

21 January 2018

1 reference

A cascade of protein kinase C isozymes promotes cytoskeletal polarization in T cells

21 January 2018

1 reference

Spatiotemporal control of cell signalling using a light-switchable protein interaction.

21 January 2018

1 reference

Rapid blue-light-mediated induction of protein interactions in living cells

21 January 2018

1 reference

Phosphatidylinositol (4,5) bisphosphate controls T cell activation by regulating T cell rigidity and organization

21 January 2018

1 reference

The duration of antigenic stimulation determines the fate of naive and effector T cells.

21 January 2018

1 reference

Continuous T cell receptor signaling required for synapse maintenance and full effector potential

21 January 2018

1 reference

Defective TCR expression in transgenic mice constructed using cDNA-based α- and β-chain genes under the control of heterologous regulatory elements

21 January 2018

1 reference