(Q38165146)

30 August 2017

title

Targeted delivery of genes to endothelial cells and cell- and gene-based therapy in pulmonary vascular diseases (English)

1 reference

30 August 2017

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24265244%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Shirley H J Mei

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24265244%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

author name string

Lakshmi Kugathasan

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24265244%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Duncan J Stewart

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24265244%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

publication date

1 October 2013

1 reference

30 August 2017

published in

Comprehensive Physiology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24265244%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

volume

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24265244%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24265244%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

page(s)

1749-1779

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24265244%20AND%20SRC:MED&resulttype=core&format=json

Mesenchymal stem cells and the artery wall.

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Gene therapy death prompts review of adenovirus vector

21 January 2018

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Use of minicircle plasmids for gene therapy.

21 January 2018

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Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Atrial natriuretic peptide gene transfection with a novel envelope vector system ameliorates pulmonary hypertension in rats.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Gene transfer of human prostacyclin synthase ameliorates monocrotaline-induced pulmonary hypertension in rats.

21 January 2018

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Immunomodulatory properties of mesenchymal stromal cells

21 January 2018

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https://api.crossref.org/works/10.1002%2FCPHY.C120034

Bone marrow stromal cells attenuate sepsis via prostaglandin E(2)-dependent reprogramming of host macrophages to increase their interleukin-10 production

21 January 2018

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Simvastatin rescues rats from fatal pulmonary hypertension by inducing apoptosis of neointimal smooth muscle cells.

21 January 2018

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Bone marrow-derived endothelial progenitor cells are a major determinant of nascent tumor neovascularization

21 January 2018

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Prostacyclin release and receptor activation: differential control of human pulmonary venous and arterial tone

21 January 2018

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https://api.crossref.org/works/10.1002%2FCPHY.C120034

Gene transfer of hepatocyte growth factor with prostacyclin synthase in severe pulmonary hypertension of rats

21 January 2018

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https://api.crossref.org/works/10.1002%2FCPHY.C120034

Hepatocyte growth factor suppresses vascular medial hyperplasia and matrix accumulation in advanced pulmonary hypertension of rats

21 January 2018

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https://api.crossref.org/works/10.1002%2FCPHY.C120034

Innate immunity in the therapeutic actions of endothelial progenitor cells in pulmonary hypertension

21 January 2018

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https://api.crossref.org/works/10.1002%2FCPHY.C120034

Long-term ambrisentan therapy for the treatment of pulmonary arterial hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Concise review: mesenchymal stem/multipotent stromal cells: the state of transdifferentiation and modes of tissue repair--current views

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Multilineage potential of adult human mesenchymal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

In vivo gene transfer of the O2-sensitive potassium channel Kv1.5 reduces pulmonary hypertension and restores hypoxic pulmonary vasoconstriction in chronically hypoxic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

One strategy for cell and gene therapy: harnessing the power of adult stem cells to repair tissues.

21 January 2018

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https://api.crossref.org/works/10.1002%2FCPHY.C120034

Proteomic analysis reveals presence of platelet microparticles in endothelial progenitor cell cultures

21 January 2018

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https://api.crossref.org/works/10.1002%2FCPHY.C120034

Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration

21 January 2018

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https://api.crossref.org/works/10.1002%2FCPHY.C120034

Effects of bone marrow-derived cells on monocrotaline- and hypoxia-induced pulmonary hypertension in mice.

21 January 2018

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https://api.crossref.org/works/10.1002%2FCPHY.C120034

Targeted gene therapy for the treatment of heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Bone morphogenetic protein type 2 receptor gene therapy attenuates hypoxic pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Gene therapy for pulmonary hypertension: prospects and challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Combined transductional and transcriptional targeting improves the specificity of transgene expression in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

The effect of high doses of calcium-channel blockers on survival in primary pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Mesenchymal stem cells avoid allogeneic rejection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Treatment of pulmonary arterial hypertension: the role of prostacyclin and prostaglandin analogs

21 January 2018

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https://api.crossref.org/works/10.1002%2FCPHY.C120034

Biology of bone marrow-derived endothelial cell precursors

21 January 2018

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https://api.crossref.org/works/10.1002%2FCPHY.C120034

Mechanisms of disease: pulmonary arterial hypertension.

21 January 2018

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https://api.crossref.org/works/10.1002%2FCPHY.C120034

Reduced number of circulating endothelial progenitor cells predicts future cardiovascular events: proof of concept for the clinical importance of endogenous vascular repair

21 January 2018

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21 January 2018

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https://api.crossref.org/works/10.1002%2FCPHY.C120034

Generation of transgene-free lung disease-specific human induced pluripotent stem cells using a single excisable lentiviral stem cell cassette.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Regulation of bone morphogenetic protein signalling in human pulmonary vascular development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Modern age pathology of pulmonary arterial hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Interleukin-6 overexpression induces pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Cellular and molecular mechanisms of pulmonary vascular remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Animal models of pulmonary arterial hypertension: the hope for etiological discovery and pharmacological cure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Increased plasma endothelin-1 in pulmonary hypertension: marker or mediator of disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Cell therapy approaches for lung diseases: current status

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Gene transfer of human prostacyclin synthase into the liver is effective for the treatment of pulmonary hypertension in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Early combined treatment with cilostazol and bone marrow-derived endothelial progenitor cells markedly attenuates pulmonary arterial hypertension in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

A receptor-targeted nanocomplex vector system optimized for respiratory gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Repeated gene transfer of naked prostacyclin synthase plasmid into skeletal muscles attenuates monocrotaline-induced pulmonary hypertension and prolongs survival in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Transplantation of endothelial progenitor cells into the lung to alleviate pulmonary hypertension in dogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Mesenchymal stem cell-based prostacyclin synthase gene therapy for pulmonary hypertension rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Bone morphogenetic protein receptor-2 signaling promotes pulmonary arterial endothelial cell survival: implications for loss-of-function mutations in the pathogenesis of pulmonary hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Progress and problems with the use of viral vectors for gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Sporadic primary pulmonary hypertension is associated with germline mutations of the gene encoding BMPR-II, a receptor member of the TGF-beta family

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Increased pulmonary artery elastolytic activity in adult rats with monocrotaline-induced progressive hypertensive pulmonary vascular disease compared with infant rats with nonprogressive disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Evidence of dysfunction of endothelial progenitors in pulmonary arterial hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Gene delivery by lipoplexes and polyplexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

The pathobiology of pulmonary hypertension. Endothelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Pathology of pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Allogenic stem cell therapy improves right ventricular function by improving lung pathology in rats with pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Soluble factors released by endothelial progenitor cells promote migration of endothelial cells and cardiac resident progenitor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Endothelial progenitor cells: characterization and role in vascular biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Relevance of monocytic features for neovascularization capacity of circulating endothelial progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Gene therapy for inherited lung disorders: an insight into pulmonary defence

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Inhibition of matrix metalloproteinases by lung TIMP-1 gene transfer limits monocrotaline-induced pulmonary vascular remodeling in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Pathobiology of pulmonary arterial hypertension and right ventricular failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Engineering targeted viral vectors for gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Safety and biological efficacy of an adeno-associated virus vector-cystic fibrosis transmembrane regulator (AAV-CFTR) in the cystic fibrosis maxillary sinus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Circulating endothelial progenitor cells and cardiovascular outcomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Antiproliferative effects of phosphodiesterase type 5 inhibition in human pulmonary artery cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Holding our breath: The emerging and anticipated roles of microRNA in pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Distribution of obstructive intimal lesions and their cellular phenotypes in chronic pulmonary hypertension. A morphometric and immunohistochemical study

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Autologous transplantation of bone marrow-derived endothelial progenitor cells attenuates monocrotaline-induced pulmonary arterial hypertension in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Human endothelial progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Redefining endothelial progenitor cells via clonal analysis and hematopoietic stem/progenitor cell principals

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Pathogenesis of pulmonary arterial hypertension: the need for multiple hits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Effect of prepro-calcitonin gene-related peptide-expressing endothelial progenitor cells on pulmonary hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Protective role of angiopoietin-1 in experimental pulmonary hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Rescue of monocrotaline-induced pulmonary arterial hypertension using bone marrow-derived endothelial-like progenitor cells: efficacy of combined cell and eNOS gene therapy in established disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Microvascular regeneration in established pulmonary hypertension by angiogenic gene transfer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Gene delivery of cytochrome p450 epoxygenase ameliorates monocrotaline-induced pulmonary artery hypertension in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

The endogenous vascular elastase that governs development and progression of monocrotaline-induced pulmonary hypertension in rats is a novel enzyme related to the serine proteinase adipsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

BMPR2 gene rearrangements account for a significant proportion of mutations in familial and idiopathic pulmonary arterial hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Intratracheal mesenchymal stem cell administration attenuates monocrotaline-induced pulmonary hypertension and endothelial dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

Formation of plexiform lesions in experimental severe pulmonary arterial hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

7 January 2021

Alterations of growth factor transcripts in rat lungs during development of monocrotaline-induced pulmonary hypertension

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

7 January 2021

Adeno-associated virus Rep78 protein and terminal repeats enhance integration of DNA sequences into the cellular genome

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

7 January 2021

Treatment of pulmonary arterial hypertension with the selective endothelin-A receptor antagonist sitaxsentan

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

7 January 2021

In vivo gene transfer of prepro-calcitonin gene-related peptide to the lung attenuates chronic hypoxia-induced pulmonary hypertension in the mouse

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

7 January 2021

Gene transfer in intact animals

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

7 January 2021

Endothelial cells of hematopoietic origin make a significant contribution to adult blood vessel formation

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

7 January 2021

Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

7 January 2021

Pulmonary hypertension

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

7 January 2021

Primary pulmonary hypertension

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

7 January 2021

Tumor response to radiotherapy regulated by endothelial cell apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

7 January 2021

Adipose-derived mesenchymal stem cells alleviate experimental colitis by inhibiting inflammatory and autoimmune responses

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

7 January 2021

Plasticity of marrow-derived stem cells

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

7 January 2021

Tenascin-C is induced with progressive pulmonary vascular disease in rats and is functionally related to increased smooth muscle cell proliferation

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

7 January 2021

Therapeutic potential of ex vivo expanded endothelial progenitor cells for myocardial ischemia

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

7 January 2021

Implantation of mesenchymal stem cells improves right ventricular impairments caused by experimental pulmonary hypertension

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

7 January 2021

Hyperproliferative apoptosis-resistant endothelial cells in idiopathic pulmonary arterial hypertension

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

7 January 2021

Spatio-temporal diversity of apoptosis within the vascular wall in pulmonary arterial hypertension: heterogeneous BMP signaling may have therapeutic implications

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

7 January 2021

Angiotensin-converting enzyme inhibition delays pulmonary vascular neointimal formation

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

7 January 2021

Activation of matrix metalloproteinase 3 (stromelysin) and matrix metalloproteinase 2 ('gelatinase') by human neutrophil elastase and cathepsin G

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

7 January 2021

Adenovirus-mediated lung vascular endothelial growth factor overexpression protects against hypoxic pulmonary hypertension in rats

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

7 January 2021

Vascular remodeling and growth factor gene expression in the rat lung during hypoxia

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

7 January 2021

Peripheral blood "endothelial progenitor cells" are derived from monocyte/macrophages and secrete angiogenic growth factors

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

7 January 2021

Impaired transforming growth factor-beta signaling in idiopathic pulmonary arterial hypertension

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

7 January 2021

In vivo gene delivery to the pulmonary circulation in rats: transgene distribution and vascular inflammatory response

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

7 January 2021

Endothelial progenitor cells

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

7 January 2021

Initial apoptosis is followed by increased proliferation of apoptosis-resistant endothelial cells

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

7 January 2021

Divergent regulation of vascular endothelial growth factor and of erythropoietin gene expression in vivo

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

7 January 2021

In vivo gene transfer into injured carotid arteries. Optimization and evaluation of acute toxicity

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

7 January 2021

Treprostinil for the treatment of pulmonary hypertension

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

7 January 2021

Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death-dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

7 January 2021

Matrix metalloproteinase-9 expression after myocardial infarction: physiological or pathological?

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

7 January 2021

Excess collagen in hypertensive pulmonary arteries decreases vascular distensibility

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

7 January 2021

Prostacyclin synthase expression is decreased in lungs from patients with severe pulmonary hypertension

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

7 January 2021

ET-1 stimulates pulmonary arterial smooth muscle cell proliferation via induction of reactive oxygen species

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

7 January 2021

Stem cells and cell therapies in lung biology and lung diseases

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

7 January 2021

Plexiform-like lesions and increased tissue factor expression in a rat model of severe pulmonary arterial hypertension

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

7 January 2021

5-Lipoxygenase and 5-lipoxygenase activating protein (FLAP) immunoreactivity in lungs from patients with primary pulmonary hypertension

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

7 January 2021

Synergistic neovascularization by mixed transplantation of early endothelial progenitor cells and late outgrowth endothelial cells: the role of angiogenic cytokines and matrix metalloproteinases

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

7 January 2021

Bone morphogenetic proteins induce apoptosis in human pulmonary vascular smooth muscle cells

1 reference

https://api.crossref.org/works/10.1002%2FCPHY.C120034

7 January 2021