(Q35120176)

6 August 2017

1 reference

title

Progress and problems with the use of viral vectors for gene therapy (English)

1 reference

6 August 2017

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12728277

30 December 2023

1 reference

30 December 2023

2

Anja Ehrhardt

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12728277

30 December 2023

3

Mark A. Kay

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12728277

30 December 2023

author name string

Clare E. Thomas

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12728277

30 December 2023

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12728277

30 December 2023

publication date

1 May 2003

1 reference

full work available at URL

6 August 2017

https://www.nature.com/articles/nrg1066.pdf

file format

Portable Document Format

1 reference

https://www.nature.com/articles/nrg1066

30 December 2023

1 reference

30 December 2023

published in

Nature Reviews Genetics

1 reference

6 August 2017

volume

4

1 reference

6 August 2017

issue

5

1 reference

6 August 2017

page(s)

346-358

1 reference

https://scigraph.springernature.com/pub.10.1038/nrg1066

6 August 2017

exact match

0 references

cites work

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31 March 2020

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A new adenoviral helper-dependent vector results in long-term therapeutic levels of human coagulation factor IX at low doses in vivo

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31 March 2020

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Therapeutic factor VIII levels and negligible toxicity in mouse and dog models of hemophilia A following gene therapy with high-capacity adenoviral vectors

31 March 2020

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Peripheral infection with adenovirus causes unexpected long-term brain inflammation in animals injected intracranially with first-generation, but not with high-capacity, adenovirus vectors: toward realistic long-term neurological gene therapy for ch

31 March 2020

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Acute direct adenoviral vector cytotoxicity and chronic, but not acute, inflammatory responses correlate with decreased vector-mediated transgene expression in the brain

31 March 2020

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Lethal toxicity, severe endothelial injury, and a threshold effect with high doses of an adenoviral vector in baboons

31 March 2020

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Induction of immunity to antigens expressed by recombinant adeno-associated virus depends on the route of administration

31 March 2020

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Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy

31 March 2020

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Targeting retroviral vector infection to cells that express heregulin receptors using a TVA-heregulin bridge protein

31 March 2020

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Conjugate-based targeting of recombinant adeno-associated virus type 2 vectors by using avidin-linked ligands

31 March 2020

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Combined transductional and transcriptional targeting improves the specificity of transgene expression in vivo

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31 March 2020

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31 March 2020

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Distinct classes of factor-independent mutants can be isolated after retroviral mutagenesis of a human myeloid stem cell line

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Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease

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A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency

31 March 2020

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Side effects of retroviral gene transfer into hematopoietic stem cells

31 March 2020

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HIV-1 integration in the human genome favors active genes and local hotspots

31 March 2020

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Site-specific genomic integration produces therapeutic Factor IX levels in mice

31 March 2020

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Stable nonviral genetic correction of inherited human skin disease

31 March 2020

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A phage integrase directs efficient site-specific integration in human cells

31 March 2020

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Extrachromosomal recombinant adeno-associated virus vector genomes are primarily responsible for stable liver transduction in vivo

31 March 2020

1 reference

Chromosomal effects of adeno-associated virus vector integration

31 March 2020

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DNA synthesis and topoisomerase inhibitors increase transduction by adeno-associated virus vectors

31 March 2020

1 reference

A limited number of transducible hepatocytes restricts a wide-range linear vector dose response in recombinant adeno-associated virus-mediated liver transduction

31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

1 reference

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31 March 2020

1 reference

Tumor-specific gene expression in hepatic metastases by a replication-activated adenovirus vector

31 March 2020

1 reference

Circular intermediates of recombinant adeno-associated virus have defined structural characteristics responsible for long-term episomal persistence in muscle tissue

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Assessment of adenoviral vector safety and toxicity: report of the National Institutes of Health Recombinant DNA Advisory Committee

series ordinal

40

1 reference

30 December 2023

A tragic setback

series ordinal

91

1 reference

30 December 2023

115

60

6359

J Nemunaitis

2000

1 reference

30 December 2023

Identifiers

DOI

10.1038/NRG1066

1 reference

Dimensions Publication ID

6 August 2017

1003654890

0 references

1 reference