(Q36868494)

16 August 2017

1 reference

title

Engineering targeted viral vectors for gene therapy (English)

1 reference

16 August 2017

0 references

3

David T Curiel

1 reference

16 August 2017

2

Stephen J Russell

1 reference

16 August 2017

Reinhard Waehler

1

1 reference

16 August 2017

3 July 2007

1 reference

16 August 2017

Nature Reviews Genetics

1 reference

16 August 2017

8

1 reference

16 August 2017

573-587

1 reference

16 August 2017

8

1 reference

https://scigraph.springernature.com/pub.10.1038/nrg2141

16 August 2017

0 references

cites work

Oncolytic viral therapies - the clinical experience

1 reference

Targeted gene therapy for ovarian cancer

31 March 2020

1 reference

Why did p53 gene therapy fail in ovarian cancer?

31 March 2020

1 reference

Transcriptionally targeted adenovirus vectors

31 March 2020

1 reference

Gene therapy clinical trials worldwide 1989-2004-an overview.

31 March 2020

1 reference

Nuclear gene delivery: the Trojan horse approach

31 March 2020

1 reference

Altering the tropism of lentiviral vectors through pseudotyping

31 March 2020

1 reference

Pseudotyping of murine leukemia virus with the envelope glycoproteins of HIV generates a retroviral vector with specificity of infection for CD4-expressing cells

31 March 2020

1 reference

Pseudotyped lentivirus vectors derived from simian immunodeficiency virus SIVagm with envelope glycoproteins from paramyxovirus

31 March 2020

1 reference

Lentiviral vector retargeting to P-glycoprotein on metastatic melanoma through intravenous injection

31 March 2020

1 reference

Cell-specific targeting of Sindbis virus vectors displaying IgG-binding domains of protein A.

31 March 2020

1 reference

Construction of a novel virus that targets HIV-1-infected cells and controls HIV-1 infection

31 March 2020

1 reference

Targeting of HIV- and SIV-infected cells by CD4-chemokine receptor pseudotypes

31 March 2020

1 reference

Retroviral vector targeting to human immunodeficiency virus type 1-infected cells by receptor pseudotyping

31 March 2020

1 reference

A chimeric adenovirus vector encoding reovirus attachment protein sigma1 targets cells expressing junctional adhesion molecule 1.

31 March 2020

1 reference

An adenovirus vector with a chimeric fiber incorporating stabilized single chain antibody achieves targeted gene delivery

31 March 2020

1 reference

A Hybrid Vector for Ligand-Directed Tumor Targeting and Molecular Imaging

31 March 2020

1 reference

Metabolically biotinylated adenovirus for cell targeting, ligand screening, and vector purification

31 March 2020

1 reference

Enhanced gene transfer to mouse dendritic cells using adenoviral vectors coated with a novel adapter molecule

31 March 2020

1 reference

Adenovirus tumor targeting and hepatic untargeting by a coxsackie/adenovirus receptor ectodomain anti-carcinoembryonic antigen bispecific adapter

31 March 2020

1 reference

Targeting retroviral vector infection to cells that express heregulin receptors using a TVA-heregulin bridge protein

31 March 2020

1 reference

Redirecting coronavirus to a nonnative receptor through a virus-encoded targeting adapter

31 March 2020

1 reference

Targeting adenoviral vectors using heterofunctional polyethylene glycol FGF2 conjugates

31 March 2020

1 reference

A novel strategy to modify adenovirus tropism and enhance transgene delivery to activated vascular endothelial cells in vitro and in vivo

31 March 2020

1 reference

Evaluation of polyethylene glycol modification of first-generation and helper-dependent adenoviral vectors to reduce innate immune responses

31 March 2020

1 reference

PEGylated adenovirus vectors containing RGD peptides on the tip of PEG show high transduction efficiency and antibody evasion ability

31 March 2020

1 reference

PEGylation of a vesicular stomatitis virus G pseudotyped lentivirus vector prevents inactivation in serum

31 March 2020

1 reference

Combined genetic and chemical capsid modifications enable flexible and efficient de- and retargeting of adenovirus vectors

31 March 2020

1 reference

Brave new (strept)avidins in biotechnology

31 March 2020

1 reference

A versatile and potentially general approach to the targeting of specific cell types by retroviruses: application to the infection of human cells by means of major histocompatibility complex class I and class II antigens by mouse ecotropic murine le

31 March 2020

1 reference

The efficiency of cell targeting by recombinant retroviruses depends on the nature of the receptor and the composition of the artificial cell-virus linker

31 March 2020

1 reference

Avidin-based targeting and purification of a protein IX-modified, metabolically biotinylated adenoviral vector.

31 March 2020

1 reference

Comparison of adenovirus fiber, protein IX, and hexon capsomeres as scaffolds for vector purification and cell targeting

31 March 2020

1 reference

Recombinant adenovirus type 5 vectors that target DC-SIGN, ChemR23 and alpha(v)beta3 integrin efficiently transduce human dendritic cells and enhance presentation of vectored antigens

31 March 2020

1 reference

Metabolic biotinylation provides a unique platform for the purification and targeting of multiple AAV vector serotypes

31 March 2020

1 reference

Targeting of vaccinia virus using biotin-avidin viral coating and biotinylated antibodies

31 March 2020

1 reference

Drug insight: using monoclonal antibodies to treat multiple sclerosis

31 March 2020

1 reference

Comparing antibody and small-molecule therapies for cancer

31 March 2020

1 reference

Altering AAV tropism with mosaic viral capsids.

31 March 2020

1 reference

Targeting of adenovirus via genetic modification of the viral capsid combined with a protein bridge

31 March 2020

1 reference

Antibody-mediated targeting of replication-competent retroviral vectors

31 March 2020

1 reference

Retroviral vectors displaying functional antibody fragments

31 March 2020

1 reference

Development of novel cell surface CD34-targeted recombinant adenoassociated virus vectors for gene therapy

31 March 2020

1 reference

Efficient retroviral vector targeting of carcinoembryonic antigen-positive tumors

31 March 2020

1 reference

Rescue and propagation of fully retargeted oncolytic measles viruses

31 March 2020

1 reference

A herpes simplex virus recombinant that exhibits a single-chain antibody to HER2/neu enters cells through the mammary tumor receptor, independently of the gD receptors

31 March 2020

1 reference

Characterization of a recombinant herpes simplex virus 1 designed to enter cells via the IL13Ralpha2 receptor of malignant glioma cells

31 March 2020

1 reference

Novel lentiviral vectors displaying "early-acting cytokines" selectively promote survival and transduction of NOD/SCID repopulating human hematopoietic stem cells.

31 March 2020

1 reference

The effects of N-terminal insertion into VSV-G of an scFv peptide

31 March 2020

1 reference

Genetic retargeting of adenovirus vectors: functionality of targeting ligands and their influence on virus viability

31 March 2020

1 reference

Organization of the functions and components of the endoplasmic reticulum

31 March 2020

1 reference

Modification of retroviral tropism by display of IGF-I.

31 March 2020

1 reference

Targeted retroviral vectors displaying a cleavage site-engineered hemagglutinin (HA) through HA-protease interactions

31 March 2020

1 reference

Envelope-targeted retrovirus vectors transduce melanoma xenografts but not spleen or liver.

31 March 2020

1 reference

Organ distribution of gene expression after intravenous infusion of targeted and untargeted lentiviral vectors.

31 March 2020

1 reference

Molecular and cellular biology of von Willebrand factor

31 March 2020

1 reference

Systemic administration of a matrix-targeted retroviral vector is efficacious for cancer gene therapy in mice

31 March 2020

1 reference

Mosaic vectors comprised of modified AAV1 capsid proteins for efficient vector purification and targeting to vascular endothelial cells

31 March 2020

1 reference

Gene transfer to carcinoma of the breast with fiber-modified adenoviral vectors in a tissue slice model system

31 March 2020

1 reference

Preclinical evaluation of a class of infectivity-enhanced adenoviral vectors in ovarian cancer gene therapy

31 March 2020

1 reference

Redirecting retroviral tropism by insertion of short, nondisruptive peptide ligands into envelope

31 March 2020

1 reference

Decreasing the metastatic potential in cancers--targeting the heparan sulfate proteoglycans

31 March 2020

1 reference

Polylysine modification of adenoviral fiber protein enhances muscle cell transduction

31 March 2020

1 reference

Ovarian cancer targeted adenoviral-mediated mda-7/IL-24 gene therapy

31 March 2020

1 reference

Identifying the safety profile of a novel infectivity-enhanced conditionally replicative adenovirus, Ad5-delta24-RGD, in anticipation of a phase I trial for recurrent ovarian cancer

31 March 2020

1 reference

Directed evolution of adeno-associated virus yields enhanced gene delivery vectors

31 March 2020

1 reference

Toward cell-targeting gene therapy vectors: selection of cell-binding peptides from random peptide-presenting phage libraries

31 March 2020

1 reference

Selection of muscle-binding peptides from context-specific peptide-presenting phage libraries for adenoviral vector targeting

31 March 2020

1 reference

Selection of feline leukemia virus envelope proteins from a library by functional association with a murine leukemia virus envelope

31 March 2020

1 reference

Altering retroviral tropism using a random-display envelope library

31 March 2020

1 reference

Probing sequence variation in the receptor-targeting domain of feline leukemia virus envelope proteins with peptide display libraries

31 March 2020

1 reference

Generation and selection of targeted adenoviruses embodying optimized vector properties

31 March 2020

1 reference

Molecular breeding of viruses

31 March 2020

1 reference

Targeted gene delivery to vascular tissue in vivo by tropism-modified adeno-associated virus vectors

31 March 2020

1 reference

The influence of adenovirus fiber structure and function on vector development for gene therapy

31 March 2020

1 reference

Transcytosis of infectious human immunodeficiency virus across a tight human epithelial cell line barrier

31 March 2020

1 reference

AAV transcytosis through barrier epithelia and endothelium

31 March 2020

1 reference

Transport across a polarized monolayer of Caco-2 cells by transferrin receptor-mediated adenovirus transcytosis

31 March 2020

1 reference

Directing adenovirus across the blood-brain barrier via melanotransferrin (P97) transcytosis pathway in an in vitro model

31 March 2020

1 reference

Fiber-mosaic adenovirus as a novel approach to design genetically modified adenoviral vectors

31 March 2020

1 reference

Oncolytic measles viruses for cancer therapy

31 March 2020

1 reference

Targeted measles virus vector displaying echistatin infects endothelial cells via alpha(v)beta3 and leads to tumor regression

31 March 2020

1 reference

Oncolytic measles viruses displaying a single-chain antibody against CD38, a myeloma cell marker.

31 March 2020

1 reference

The use of a tropism-modified measles virus in folate receptor-targeted virotherapy of ovarian cancer

31 March 2020

1 reference

Retargeted oncolytic measles strains entering via the EGFRvIII receptor maintain significant antitumor activity against gliomas with increased tumor specificity

31 March 2020

1 reference

Protection of MLV vector particles from human complement

31 March 2020

1 reference

Multiple innate inflammatory responses induced after systemic adenovirus vector delivery depend on a functional complement system.

31 March 2020

1 reference

Epitope mapping of human anti-adeno-associated virus type 2 neutralizing antibodies: implications for gene therapy and virus structure

31 March 2020

1 reference

Efficacy of severe acute respiratory syndrome vaccine based on a nonhuman primate adenovirus in the presence of immunity against human adenovirus

31 March 2020

1 reference

PEGylated helper-dependent adenoviral vectors: highly efficient vectors with an enhanced safety profile

31 March 2020

1 reference

Multiple vitamin K-dependent coagulation zymogens promote adenovirus-mediated gene delivery to hepatocytes

31 March 2020

1 reference

Adenovirus Binding to Blood Factors Results in Liver Cell Infection and Hepatotoxicity

31 March 2020

1 reference

Adenovirus type 5 interactions with human blood cells may compromise systemic delivery.

31 March 2020

1 reference

Assessment of recombinant adenoviral vectors for hepatic gene therapy

31 March 2020

1 reference

Transcytosis of Human immunodeficiency virus 1 across the placenta is enhanced by treatment with tumour necrosis factor alpha

31 March 2020

1 reference

Expression of coxsackie adenovirus receptor and alphav-integrin does not correlate with adenovector targeting in vivo indicating anatomical vector barriers

31 March 2020

1 reference

Mesenchymal progenitor cells as cellular vehicles for delivery of oncolytic adenoviruses

31 March 2020

1 reference

Mesenchymal stem cells as a vehicle for targeted delivery of CRAds to lung metastases of breast carcinoma

31 March 2020

1 reference

Tumor structure and extracellular matrix as a possible barrier for therapeutic approaches using immune cells or adenoviruses in colorectal cancer

31 March 2020

1 reference

Prolonged and inducible transgene expression in the liver using gutless adenovirus: a potential therapy for liver cancer.

31 March 2020

1 reference

Combining high selectivity of replication with fiber chimerism for effective adenoviral oncolysis of CAR-negative melanoma cells

31 March 2020

1 reference

Inter-patient variation in efficacy of five oncolytic adenovirus candidates for ovarian cancer therapy

31 March 2020

1 reference

Three-dimensional tissue culture models in cancer biology

31 March 2020

1 reference

A single-component CD40-targeted adenovirus vector displays highly efficient transduction and activation of dendritic cells in a human skin substrate system

31 March 2020

1 reference

Linking innate and acquired immunity: divergent role of CD46 cytoplasmic domains in T cell induced inflammation

31 March 2020

1 reference

Evaluation of adenovirus vectors containing serotype 35 fibers for vaccination

31 March 2020

1 reference

Selective induction of tumor-associated antigens in murine pulmonary vasculature using double-targeted adenoviral vectors.

31 March 2020

1 reference

In vivo analysis of a genetically modified adenoviral vector targeted to human CD40 using a novel transient transgenic model.

31 March 2020

1 reference

A mouse model for adenovirus gene delivery

31 March 2020

1 reference

An adenovirus serotype 5 vector with fibers derived from ovine atadenovirus demonstrates CAR-independent tropism and unique biodistribution in mice

31 March 2020

1 reference

Biodistribution and toxicity studies of VSVG-pseudotyped lentiviral vector after intravenous administration in mice with the observation of in vivo transduction of bone marrow

31 March 2020

1 reference

Phase I-II trial of ONYX-015 in combination with MAP chemotherapy in patients with advanced sarcomas

31 March 2020

1 reference

Noninvasive imaging of protein-protein interactions in living animals

31 March 2020

1 reference

A dual function fusion protein of Herpes simplex virus type 1 thymidine kinase and firefly luciferase for noninvasive in vivo imaging of gene therapy in malignant glioma

31 March 2020

1 reference

Molecular optical imaging: applications leading to the development of present day therapeutics

31 March 2020

1 reference

Fluorescently labeled adenovirus with pIX-EGFP for vector detection

31 March 2020

1 reference

Dynamic monitoring of oncolytic adenovirus in vivo by genetic capsid labeling

31 March 2020

1 reference

Fluorescently tagged canine adenovirus via modification with protein IX-enhanced green fluorescent protein

31 March 2020

1 reference

Genetic incorporation of HSV-1 thymidine kinase into the adenovirus protein IX for functional display on the virion

31 March 2020

1 reference

Low-dose adenoviral immunotherapy of rat hepatocellular carcinoma using single-chain interleukin-12.

31 March 2020

1 reference

Magnetic resonance imaging of viral particle biodistribution in vivo.

31 March 2020

1 reference

Adeno-associated virus serotypes: vector toolkit for human gene therapy

31 March 2020

1 reference

Modified Envelope Glycoproteins to Retarget Retroviral Vectors

31 March 2020

1 reference

Mechanism of membrane fusion by viral envelope proteins

31 March 2020

1 reference

Targeted adeno-associated virus vector transduction of nonpermissive cells mediated by a bispecific F(ab'gamma)2 antibody

31 March 2020

1 reference

Enhanced gene transfer efficiency in the murine striatum and an orthotopic glioblastoma tumor model, using AAV-7- and AAV-8-pseudotyped vectors

31 March 2020

1 reference

Combined transductional and transcriptional targeting improves the specificity of transgene expression in vivo

31 March 2020

1 reference

Targeting non-human coronaviruses to human cancer cells using a bispecific single-chain antibody

31 March 2020

1 reference

Development and assessment of human adenovirus type 11 as a gene transfer vector

31 March 2020

1 reference

Retroviral retargeting by envelopes expressing an N-terminal binding domain.

31 March 2020

1 reference

12 December 2020

Inverse targeting of retroviral vectors: selective gene transfer in a mixed population of hematopoietic and nonhematopoietic cells.

1 reference

12 December 2020

Targeting of adenovirus vectors to tumor cells does not enable efficient transduction of breast cancer metastases

1 reference

12 December 2020

Lentiviral vector targeting

1 reference

12 December 2020

Membrane-associated heparan sulfate proteoglycan is a receptor for adeno-associated virus type 2 virions

1 reference

12 December 2020

The biotin-(strept)avidin system: principles and applications in biotechnology

1 reference

12 December 2020

Replication-defective genomic HSV gene therapy vectors: design, production and CNS applications.

1 reference

12 December 2020

Technology evaluation: Rexin-G, Epeius Biotechnologies

1 reference

12 December 2020

Pathotropic nanoparticles for cancer gene therapy Rexin-G IV: three-year clinical experience

1 reference

12 December 2020

Phase II clinical trial of intralesional administration of the oncolytic adenovirus ONYX-015 in patients with hepatobiliary tumors with correlative p53 studies

1 reference

12 December 2020

Genetic incorporation of a herpes simplex virus type 1 thymidine kinase and firefly luciferase fusion into the adenovirus protein IX for functional display on the virion

1 reference

12 December 2020

Synthesis and quality control of viral membrane proteins.

1 reference

12 December 2020

Non-viral and viral vectors for gene therapy

1 reference

12 December 2020

Incorporation of fowl plague virus hemagglutinin into murine leukemia virus particles and analysis of the infectivity of the pseudotyped retroviruses

1 reference

12 December 2020

Initial binding of murine leukemia virus particles to cells does not require specific Env-receptor interaction.

1 reference

12 December 2020

Treatment of ovarian cancer with a tropism modified oncolytic adenovirus.

1 reference

12 December 2020

VSV pseudotype particles with the coat of avian myeloblastosis virus

1 reference

12 December 2020

Targeting retroviral and lentiviral vectors.

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRG2141

1 reference

release_wtn4ijm2ejafhgey23tccamylq

16 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/wtn4ijm2ejafhgey23tccamylq

24 November 2022

mapped directly with Wikidata item

PubMed ID

17607305

1 reference

PubMed ID

17607305