(Q38172423)

30 August 2017

title

TLR2 and TLR4 in autoimmune diseases: a comprehensive review (English)

1 reference

30 August 2017

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24352680%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

author name string

Heng Yin

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24352680%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Ming Zhao

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24352680%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Qianjin Lu

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24352680%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

publication date

1 October 2014

1 reference

Clinical Reviews in Allergy & Immunology

30 August 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24352680%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

volume

47

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24352680%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24352680%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

page(s)

136-147

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24352680%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/s12016-013-8402-y

11 June 2020

exact match

0 references

cites work

Hypoxia and hypoxia-inducible factor-1α provoke toll-like receptor signalling-induced inflammation in rheumatoid arthritis

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12 December 2020

TLR2 and TLR4 in the brain injury caused by cerebral ischemia and reperfusion

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Pivotal advance: HMGB1 expression in active lesions of human and experimental multiple sclerosis.

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Surface expression and genotypes of Toll-like receptors 2 and 4 in patients with juvenile idiopathic arthritis and systemic lupus erythematosus

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12 December 2020

Polymorphisms in genes controlling inflammation and tissue repair in rheumatoid arthritis: a case control study

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The role of type 1 interferon in systemic sclerosis

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TLR2 signaling improves immunoregulation to prevent type 1 diabetes

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Ubiquitin-specific protease 25 regulates TLR4-dependent innate immune responses through deubiquitination of the adaptor protein TRAF3.

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[Pathogenesis of systemic lupus erythematosus (LES)]

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The role of high mobility group box chromosomal protein 1 in rheumatoid arthritis

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The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

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12 December 2020

TLR9 and TLR4 are required for the development of autoimmunity and lupus nephritis in pristane nephropathy

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12 December 2020

CD14 and TLR4 mediate cytokine release promoted by electronegative LDL in monocytes.

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12 December 2020

TIRAP (MAL) S180L polymorphism is a common protective factor against developing tuberculosis and systemic lupus erythematosus.

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12 December 2020

Molecular control of the NEMO family of ubiquitin-binding proteins

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12 December 2020

The tyrosine kinase Syk differentially regulates Toll-like receptor signaling downstream of the adaptor molecules TRAF6 and TRAF3

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12 December 2020

PINK1 positively regulates IL-1β-mediated signaling through Tollip and IRAK1 modulation

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12 December 2020

Pathogenesis of lupus-like nephritis through autoimmune antibody produced by CD180-negative B lymphocytes in NZBWF1 mouse

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12 December 2020

Toll-like receptor (TLR) 2 is upregulated on peripheral blood monocytes of patients with psoriatic arthritis: a role for a gram-positive inflammatory trigger?

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12 December 2020

Glycoprotein 96 perpetuates the persistent inflammation of rheumatoid arthritis

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12 December 2020

Role of toll-like receptors in systemic sclerosis.

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12 December 2020

Hyaluronan differently modulates TLR-4 and the inflammatory response in mouse chondrocytes.

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12 December 2020

Knockout of toll-like receptor-2 attenuates both the proinflammatory state of diabetes and incipient diabetic nephropathy

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12 December 2020

High mobility group box protein 1 in complex with lipopolysaccharide or IL-1 promotes an increased inflammatory phenotype in synovial fibroblasts.

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12 December 2020

Toll-like receptors in health and disease: complex questions remain.

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12 December 2020

Leishmania donovani exploits host deubiquitinating enzyme A20, a negative regulator of TLR signaling, to subvert host immune response

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12 December 2020

Altered IL-10 and TNF-α production in peripheral blood mononuclear cells of systemic lupus erythematosus patients after Toll-like receptor 2, 4, or 9 activation.

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12 December 2020

Toll-like receptors and their crosstalk with other innate receptors in infection and immunity

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12 December 2020

Reprogramming of murine macrophages through TLR2 confers viral resistance via TRAF3-mediated, enhanced interferon production

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12 December 2020

Toll-like receptor 4 is involved in inflammatory and joint destructive pathways in collagen-induced arthritis in DBA1J mice

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12 December 2020

Interleukin-13-producing CD8+ T cells mediate dermal fibrosis in patients with systemic sclerosis

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12 December 2020

Autoantibody induction by DNA-containing immune complexes requires HMGB1 with the TLR2/microRNA-155 pathway.

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12 December 2020

Implication of the Toll-like receptor 4 pathway in the response to interferon-β in multiple sclerosis.

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12 December 2020

Bacterial lipopolysaccharides form procollagen-endotoxin complexes that trigger cartilage inflammation and degeneration: implications for the development of rheumatoid arthritis

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12 December 2020

Procyanidin dimer B2-mediated IRAK-M induction negatively regulates TLR4 signaling in macrophages

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12 December 2020

Association of TLR4 gene non-missense single nucleotide polymorphisms with rheumatoid arthritis in Chinese Han population.

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12 December 2020

Distinct evolution of TLR-mediated dendritic cell cytokine secretion in patients with limited and diffuse cutaneous systemic sclerosis

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12 December 2020

Mutational analysis identifies residues crucial for homodimerization of myeloid differentiation factor 88 (MyD88) and for its function in immune cells.

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12 December 2020

Toll-like receptor in salivary glands from patients with Sjögren's syndrome: functional analysis by human salivary gland cell line

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12 December 2020

Intrinsic and extrinsic regulation of innate immune receptors

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12 December 2020

Increased TLR2 expression in patients with type 1 diabetes: evidenced risk of microalbuminuria.

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12 December 2020

SHPS-1 and a synthetic peptide representing its ITIM inhibit the MyD88, but not TRIF, pathway of TLR signaling through activation of SHP and PI3K in THP-1 cells

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12 December 2020

Regulation of Toll-like receptor signaling pathways in innate immune responses

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12 December 2020

Toll-like receptor 4 signalling is specifically TGF-beta-activated kinase 1 independent in synovial fibroblasts

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12 December 2020

Gadolinium compounds signaling through TLR4 and TLR7 in normal human macrophages: establishment of a proinflammatory phenotype and implications for the pathogenesis of nephrogenic systemic fibrosis

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12 December 2020

CD300a and CD300f differentially regulate the MyD88 and TRIF-mediated TLR signalling pathways through activation of SHP-1 and/or SHP-2 in human monocytic cell lines

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12 December 2020

Demonstration of increased toll-like receptor 2 and toll-like receptor 4 expression in monocytes of type 1 diabetes mellitus patients with microvascular complications

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12 December 2020

Infectious diseases in patients with IRAK-4, MyD88, NEMO, or IκBα deficiency

1 reference

12 December 2020

Increased gene expression of Toll-like receptor 4 on peripheral blood mononuclear cells in patients with psoriasis

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12 December 2020

The Toll-like receptor 4 ligands Mrp8 and Mrp14 are crucial in the development of autoreactive CD8+ T cells.

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12 December 2020

Lipoteichoic acid enhances IL-6 production in human synovial fibroblasts via TLR2 receptor, PKCdelta and c-Src dependent pathways

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12 December 2020

Lifting the silver flakes: the pathogenesis and management of chronic plaque psoriasis

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12 December 2020

Celastrol inhibits lipopolysaccharide-stimulated rheumatoid fibroblast-like synoviocyte invasion through suppression of TLR4/NF-κB-mediated matrix metalloproteinase-9 expression

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12 December 2020

Transgenic overexpression of anti-double-stranded DNA autoantibody and activation of Toll-like receptor 4 in mice induce severe systemic lupus erythematosus syndromes

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12 December 2020

Overexpression of toll-like receptors 3 and 4 in synovial tissue from patients with early rheumatoid arthritis: toll-like receptor expression in early and longstanding arthritis.

1 reference

12 December 2020

Increased production of IL-6 and IL-17 in lipopolysaccharide-stimulated peripheral mononuclears from patients with rheumatoid arthritis

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12 December 2020

Toll-like receptors' pathway disturbances are associated with increased susceptibility to infections in humans

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12 December 2020

[The role of TLR2/4 in the IL-10 expression in synoviocytes of rheumatoid arthritis induced by Hsp72]

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12 December 2020

Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis

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12 December 2020

Host cell signalling and leishmania mechanisms of evasion.

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12 December 2020

Inhibition of autoimmune diabetes by TLR2 tolerance

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12 December 2020

Expression of functional Toll-like receptors by salivary gland epithelial cells: increased mRNA expression in cells derived from patients with primary Sjögren's syndrome

1 reference

12 December 2020

Role for toll-like receptors in autoimmune disease: the example of systemic lupus erythematosus

1 reference

12 December 2020

Toll-like receptors as therapeutic targets for autoimmune connective tissue diseases

1 reference

12 December 2020

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

1 reference

12 December 2020

Toll-like receptor 4 signaling augments transforming growth factor-β responses: a novel mechanism for maintaining and amplifying fibrosis in scleroderma

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12 December 2020

Systemic lupus erythematosus

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12 December 2020

Review of the pharmacoeconomics of early treatment of multiple sclerosis using interferon beta

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12 December 2020

HMGB1 promotes the differentiation of Th17 via up-regulating TLR2 and IL-23 of CD14+ monocytes from patients with rheumatoid arthritis

1 reference

12 December 2020

Role of TLR2 in the pathogenesis of autoimmune diabetes and its therapeutic implication

1 reference

12 December 2020

Critical role of TLR2 and TLR4 in autoantibody production and glomerulonephritis in lpr mutation-induced mouse lupus

1 reference

12 December 2020

Expression of toll-like receptors 2 and 4 in rheumatoid synovial tissue and regulation by proinflammatory cytokines interleukin-12 and interleukin-18 via interferon-gamma

1 reference

12 December 2020

CD19 regulates skin and lung fibrosis via Toll-like receptor signaling in a model of bleomycin-induced scleroderma.

1 reference

12 December 2020

MicroRNAs and toll-like receptor/interleukin-1 receptor signaling

1 reference

12 December 2020

Toll-like receptor--a potent driving force behind rheumatoid arthritis

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12 December 2020

Rheumatoid arthritis progression mediated by activated synovial fibroblasts

1 reference

12 December 2020

The role of toll-like receptors in rheumatoid arthritis

1 reference

12 December 2020

TLR4 regulates cardiac lipid accumulation and diabetic heart disease in the nonobese diabetic mouse model of type 1 diabetes

1 reference

12 December 2020

SNAPIN: an endogenous Toll-like receptor ligand in rheumatoid arthritis

1 reference

12 December 2020

Enhanced interleukin-10 production by dendritic cells upon stimulation with Toll-like receptor 4 agonists in systemic sclerosis that is possibly implicated in CCL18 secretion.

1 reference

12 December 2020

Antifibroblast antibodies in systemic sclerosis induce fibroblasts to produce profibrotic chemokines, with partial exploitation of toll-like receptor 4.

1 reference

12 December 2020

Lack of association of TLR4 polymorphisms with susceptibility to rheumatoid arthritis and ankylosing spondylitis: a meta-analysis.

1 reference

12 December 2020

SOCS proteins in development and disease

1 reference

12 December 2020

TLR-signaling networks: an integration of adaptor molecules, kinases, and cross-talk.

1 reference

12 December 2020

Toll-like receptor 4 on islet β cells senses expression changes in high-mobility group box 1 and contributes to the initiation of type 1 diabetes

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12 December 2020

The interleukin-1 receptor/Toll-like receptor superfamily: 10 years of progress.

1 reference

12 December 2020

Comparative sequence analysis of leucine-rich repeats (LRRs) within vertebrate toll-like receptors

1 reference

12 December 2020

Up-regulated expression of Toll-like receptors mRNAs in peripheral blood mononuclear cells from patients with systemic lupus erythematosus.

1 reference

12 December 2020

The Interferon-Signature of Sjögren's Syndrome: How Unique Biomarkers Can Identify Underlying Inflammatory and Immunopathological Mechanisms of Specific Diseases

1 reference

12 December 2020

Toll-like receptor 4 signaling in T cells promotes autoimmune inflammation

1 reference

12 December 2020

Signaling via the RIP2 adaptor protein in central nervous system-infiltrating dendritic cells promotes inflammation and autoimmunity

1 reference

12 December 2020

Toll-like receptor 2 induced angiogenesis and invasion is mediated through the Tie2 signalling pathway in rheumatoid arthritis.

1 reference

12 December 2020

TLR2 ligation induces the production of IL-23/IL-17 via IL-6, STAT3 and NF-kB pathway in patients with primary Sjogren's syndrome

1 reference

12 December 2020

Toll-like receptor polymorphisms and rheumatoid arthritis: a systematic review

1 reference

12 December 2020

The role of Toll-like receptor pathways in the mechanism of type 1 diabetes

1 reference

12 December 2020

Pathogenesis of type 1 diabetes: lessons from natural history studies of high-risk individuals

1 reference

12 December 2020

TRAF-interacting protein (TRIP) negatively regulates IFN-β production and antiviral response by promoting proteasomal degradation of TANK-binding kinase 1

1 reference

12 December 2020

Toll-like receptors regulate B cell cytokine production in patients with diabetes

1 reference

12 December 2020

Adaptors in toll-like receptor signaling and their potential as therapeutic targets

1 reference

12 December 2020

The E3 ubiquitin ligase Triad3A negatively regulates the RIG-I/MAVS signaling pathway by targeting TRAF3 for degradation

1 reference

12 December 2020

Protection against autoimmune nephritis in MyD88-deficient MRL/lpr mice

1 reference

12 December 2020

Toll-like receptor 2/4 links to free fatty acid-induced inflammation and β-cell dysfunction

1 reference

12 December 2020

UXT plays dual opposing roles on SARM-induced apoptosis

1 reference

12 December 2020

Total coumarins from Urtica dentata Hand prevent murine autoimmune diabetes via suppression of the TLR4-signaling pathways.

1 reference

12 December 2020

The proteoglycan biglycan regulates expression of the B cell chemoattractant CXCL13 and aggravates murine lupus nephritis

1 reference

12 December 2020

E3 ligase WWP2 negatively regulates TLR3-mediated innate immune response by targeting TRIF for ubiquitination and degradation

1 reference

12 December 2020

Intrinsic danger: activation of Toll-like receptors in rheumatoid arthritis

1 reference

12 December 2020

Direct activation of protein kinases by unanchored polyubiquitin chains

1 reference

12 December 2020

Toll-like receptors 2 and 4: initiators of non-septic inflammation in critical care medicine?

1 reference

12 December 2020

TRIF-mediated TLR3 and TLR4 signaling is negatively regulated by ADAM15.

1 reference

12 December 2020

Hyaluronan blocks oligodendrocyte progenitor maturation and remyelination through TLR2

1 reference

12 December 2020

Increased responsiveness to toll-like receptor 4 stimulation in peripheral blood mononuclear cells from patients with recent onset rheumatoid arthritis

1 reference

12 December 2020

Activation of the type I interferon pathway in primary Sjögren's syndrome: an update

1 reference

12 December 2020

Essential roles of K63-linked polyubiquitin-binding proteins TAB2 and TAB3 in B cell activation via MAPKs.

1 reference

12 December 2020

Structural Analyses of Human Toll-like Receptor 4 Polymorphisms D299G and T399I

1 reference

12 December 2020

The structural biology of Toll-like receptors

1 reference

12 December 2020

Lipopolysaccharide increases the incidence of collagen-induced arthritis in mice through induction of protease HTRA-1 expression

1 reference

12 December 2020

Knockout of toll-like receptor-4 attenuates the pro-inflammatory state of diabetes

1 reference

12 December 2020

The Toll-like receptor 4 Asp299Gly functional variant is associated with decreased rheumatoid arthritis disease susceptibility but does not influence disease severity and/or outcome

1 reference

12 December 2020

Triad3A, an E3 ubiquitin-protein ligase regulating Toll-like receptors

1 reference

12 December 2020