(Q38185880)

30 August 2017

title

Granulocyte macrophage colony-stimulating factor and the intestinal innate immune cell homeostasis in Crohn's disease (English)

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30 August 2017

1

Jan Däbritz

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language of work or name

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6 February 2014

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American Journal of Physiology - Gastrointestinal and Liver Physiology

30 August 2017

published in

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30 August 2017

volume

306

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30 August 2017

issue

6

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30 August 2017

page(s)

G455-65

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Interactions between the host innate immune system and microbes in inflammatory bowel disease

30 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Essential role for CD103 in the T cell-mediated regulation of experimental colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Granulocyte-macrophage colony-stimulating factor elicits bone marrow-derived cells that promote efficient colonic mucosal healing

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Origin of the lamina propria dendritic cell network

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Toll-like receptor-induced granulocyte-macrophage colony-stimulating factor secretion is impaired in Crohn's disease by nucleotide oligomerization domain 2-dependent and -independent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Recent advances in inflammatory bowel disease: mucosal immune cells in intestinal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

The molecular basis of pulmonary alveolar proteinosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Revisiting Crohn's disease as a primary immunodeficiency of macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Modulation of dendritic cells using granulocyte-macrophage colony-stimulating factor (GM-CSF) delays type 1 diabetes by enhancing CD4+CD25+ regulatory T cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Molecular mechanisms regulating myeloid-derived suppressor cell differentiation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

The role of granulocyte macrophage-colony stimulating factor in gastrointestinal immunity to salmonellosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Immune and nonimmune components orchestrate the pathogenesis of inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

New therapies for inflammatory bowel disease: from the bench to the bedside

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

An open-label pilot study of granulocyte colony-stimulating factor for the treatment of severe endoscopic postoperative recurrence in Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

New pathogenic paradigms in inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Hierarchy of immunosuppressive strength among myeloid-derived suppressor cell subsets is determined by GM-CSF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

A dual role for the immune response in a mouse model of inflammation-associated lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Increased prevalence of luminal narrowing and stricturing identified by enterography in pediatric Crohn's disease patients with elevated granulocyte-macrophage colony stimulating factor autoantibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

GM-CSF: a role in immune and inflammatory reactions in the intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

GM-CSF produced by nonhematopoietic cells is required for early epithelial cell proliferation and repair of injured colonic mucosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Contributions of dendritic cells and macrophages to intestinal homeostasis and immune defense

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Impact of reducing peginterferon alfa-2a and ribavirin dose during retreatment in patients with chronic hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Crohn's disease: an immunodeficiency?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Myeloid-derived suppressor cells as regulators of the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Coordinated regulation of myeloid cells by tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

GM-CSF-induced CD11c+CD8a--dendritic cells facilitate Foxp3+ and IL-10+ regulatory T cell expansion resulting in suppression of autoimmune thyroiditis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Homeostasis and inflammation in the intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Granulocyte-macrophage colony-stimulating factor autoantibodies: a marker of aggressive Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Granulocyte-macrophage colony-stimulating factor prevents diabetes development in NOD mice by inducing tolerogenic dendritic cells that sustain the suppressive function of CD4+CD25+ regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Development of monocytes, macrophages, and dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Inflammatory bowel disease: is it a primary immunodeficiency?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Defective leukocyte GM-CSF receptor (CD116) expression and function in inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Intestinal epithelial cells as mediators of the commensal-host immune crosstalk

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Myeloid derived suppressor cells in human diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

GM-CSF controls nonlymphoid tissue dendritic cell homeostasis but is dispensable for the differentiation of inflammatory dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Growth factor pleiotropy is controlled by a receptor Tyr/Ser motif that acts as a binary switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Immune suppression: the hallmark of myeloid derived suppressor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Colony-stimulating factors in inflammation and autoimmunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Colony stimulating factors and myeloid cell biology in health and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Loss of GM-CSF signalling in non-haematopoietic cells increases NSAID ileal injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Granulocyte-macrophage colony-stimulating factor autoantibodies in murine ileitis and progressive ileal Crohn's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

The GM-CSF receptor family: mechanism of activation and implications for disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

The granulocyte-macrophage colony-stimulating factor receptor: linking its structure to cell signaling and its role in disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Efficacy, safety and tolerability of vidofludimus in patients with inflammatory bowel disease: the ENTRANCE study

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

GM-CSF-facilitated dendritic cell recruitment and survival govern the intestinal mucosal response to a mouse enteric bacterial pathogen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Innate immunity in inflammatory bowel disease: state of the art.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Intestinal permeability barrier in Crohn's disease: the difficulty in shifting the paradigm

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Paediatric Crohn disease patients with stricturing behaviour exhibit ileal granulocyte-macrophage colony-stimulating factor (GM-CSF) autoantibody production and reduced neutrophil bacterial killing and GM-CSF bioactivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Regulation of intestinal homeostasis by innate and adaptive immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Innate and adaptive mechanisms to control [corrected] pathological intestinal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Phase I trial of sargramostim in pediatric Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Granulocyte-macrophage colony-stimulating factor (GM-CSF): a chemoattractive agent for murine leukocytes in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Genetics and pathogenesis of inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Is Crohn's disease due to defective immunity?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Is Crohn's disease an immunodeficiency? A hypothesis suggesting possible early events in the pathogenesis of Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

An open-labelled study of granulocyte colony-stimulating factor in the treatment of active Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Sargramostim for active Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Intestinal growth factors: potential use in the treatment of inflammatory bowel disease and their role in mucosal healing

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Recombinant human granulocyte colony-stimulating factor reduces colonic epithelial cell apoptosis and ameliorates murine dextran sulfate sodium-induced colitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Control of macrophage lineage populations by CSF-1 receptor and GM-CSF in homeostasis and inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Intestinal homeostasis and its breakdown in inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Defective innate immunity in inflammatory bowel disease: a Crohn's disease exclusivity?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Defective acute inflammation in Crohn's disease: a clinical investigation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Crohn's disease: an immune deficiency state

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Innate immunity in inflammatory bowel disease: a disease hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Increasing Incidence and Prevalence of the Inflammatory Bowel Diseases With Time, Based on Systematic Review

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Mucosal macrophages in intestinal homeostasis and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Protective and pathogenic functions of macrophage subsets

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Granulocyte macrophage-colony-stimulating factor autoantibodies and increased intestinal permeability in Crohn disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

A protective function for interleukin 17A in T cell-mediated intestinal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Neutralization of interleukin-17 aggravates dextran sulfate sodium-induced colitis in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

An independent subset of TLR expressing CCR2-dependent macrophages promotes colonic inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Phagocyte dysfunction and inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Subsets, expansion and activation of myeloid-derived suppressor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Inflammation switches the differentiation program of Ly6Chi monocytes from antiinflammatory macrophages to inflammatory dendritic cells in the colon.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Sargramostim (GM-CSF) for induction of remission in Crohn's disease: a cochrane inflammatory bowel disease and functional bowel disorders systematic review of randomized trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Granulocyte macrophage colony-stimulating factor ameliorates DSS-induced experimental colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Granulocyte-macrophage colony stimulating factor blockade promotes ccr9(+) lymphocyte expansion in Nod2 deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Peripheral monocyte functions and activation in patients with quiescent Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Intestinal CD103+ dendritic cells: master regulators of tolerance?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Neutrophil dysfunction in Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

The immunopathogenesis of Crohn's disease: a three-stage model

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Expression of peroxisome proliferator-activated receptor-gamma in macrophage suppresses experimentally induced colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Monocyte recruitment during infection and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

E-cadherin marks a subset of inflammatory dendritic cells that promote T cell-mediated colitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Role of resveratrol-induced CD11b(+) Gr-1(+) myeloid derived suppressor cells (MDSCs) in the reduction of CXCR3(+) T cells and amelioration of chronic colitis in IL-10(-/-) mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Granulocyte-macrophage-colony-stimulating factor-dependent peritoneal macrophage responses determine survival in experimentally induced peritonitis and sepsis in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Transplantation of granulocytic myeloid-derived suppressor cells (G-MDSCs) could reduce colitis in experimental murine models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Sargramostim in patients with Crohn's disease: results of a phase 1-2 study

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Regulation of intestinal homeostasis by dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

GM-CSF autoantibodies and neutrophil dysfunction in pulmonary alveolar proteinosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Standardized serum GM-CSF autoantibody testing for the routine clinical diagnosis of autoimmune pulmonary alveolar proteinosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Granulocyte/macrophage-colony-stimulating factor autoantibodies and myeloid cell immune functions in healthy subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Steroid-sparing properties of sargramostim in patients with corticosteroid-dependent Crohn's disease: a randomised, double-blind, placebo-controlled, phase 2 study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Role of the innate immune system in the pathogenesis of inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Intestinal lamina propria dendritic cell subsets have different origin and functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

High avidity cytokine autoantibodies in health and disease: pathogenesis and mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

CX3CR1 defines functionally distinct intestinal mononuclear phagocyte subsets which maintain their respective functions during homeostatic and inflammatory conditions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Crohn's disease: innate immunodeficiency?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Monocytes and their pathophysiological role in Crohn's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

The influence of conditioned medium from mouse intestinal epithelial cells on the proliferative activity of crypt cells: role of granulocyte-macrophage colony-stimulating factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

Granulocyte Macrophage Colony-Stimulating Factor Auto-Antibodies and Disease Relapse in Inflammatory Bowel Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00409.2013

21 January 2018

Identifiers

DOI

10.1152/AJPGI.00409.2013

1 reference

30 August 2017

1 reference