(Q38192688)

30 August 2017

1 reference

title

Cytochrome P450 pharmacogenetics in African populations: implications for public health (English)

1 reference

30 August 2017

0 references

Collet Dandara

1

0 references

Collen Masimirembwa

series ordinal

5

object named as

Collen Masimirembwa

1 reference

30 August 2017

4

Ambroise Wonkam

1 reference

30 August 2017

Marelize Swart

2

1 reference

PubMed ID

24588448

30 August 2017

Bafokeng Mpeta

series ordinal

3

1 reference

PubMed ID

24588448

30 August 2017

language of work or name

English

0 references

publication date

3 March 2014

1 reference

Expert Opinion on Drug Metabolism & Toxicology

30 August 2017

1 reference

30 August 2017

10

1 reference

30 August 2017

6

1 reference

30 August 2017

769-785

1 reference

Pharmacogenomics and patient care: one size does not fit all.

30 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Genetic studies of African populations: an overview on disease susceptibility and response to vaccines and therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

African genetic diversity: implications for human demographic history, modern human origins, and complex disease mapping

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Tuberculosis in sub-Saharan Africa: opportunities, challenges, and change in the era of antiretroviral treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

The economic and social burden of malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Incidence and preventability of adverse drug events in nursing homes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Prescribing BiDil: is it black and white?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Lesser response to angiotensin-converting-enzyme inhibitor therapy in black as compared with white patients with left ventricular dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

A review on ethnic differences in plasma triglycerides and high-density-lipoprotein cholesterol: is the lipid pattern the key factor for the low coronary heart disease rate in people of African origin?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Ethnic differences in stroke: black-white differences in the United States population. SECORDS Investigators. Southeastern Consortium on Racial Differences in Stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

The evolution of human genetic and phenotypic variation in Africa

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Colloquium paper: working toward a synthesis of archaeological, linguistic, and genetic data for inferring African population history

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Genome-wide patterns of population structure and admixture in West Africans and African Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

History of click-speaking populations of Africa inferred from mtDNA and Y chromosome genetic variation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Pharmacogenetics in Ghana: reviewing the evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Characterisation of CYP2C8, CYP2C9 and CYP2C19 polymorphisms in a Ghanaian population

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Genetic polymorphisms in MDR1, CYP3A4 and CYP3A5 genes in a Ghanaian population: a plausible explanation for altered metabolism of ivermectin in humans?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Importance of ethnicity, CYP2B6 and ABCB1 genotype for efavirenz pharmacokinetics and treatment outcomes: a parallel-group prospective cohort study in two sub-Saharan Africa populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

ABCB1 4036A>G and 1236C>T Polymorphisms Affect Plasma Efavirenz Levels in South African HIV/AIDS Patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

PXR and CAR single nucleotide polymorphisms influence plasma efavirenz levels in South African HIV/AIDS patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Long-term effect of efavirenz autoinduction on plasma/peripheral blood mononuclear cell drug exposure and CD4 count is influenced by UGT2B7 and CYP2B6 genotypes among HIV patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

High plasma efavirenz level and CYP2B6*6 are associated with efavirenz-based HAART-induced liver injury in the treatment of naïve HIV patients from Ethiopia: a prospective cohort study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Mitochondrial DNA subhaplogroups L0a2 and L2a modify susceptibility to peripheral neuropathy in malawian adults on stavudine containing highly active antiretroviral therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Influence of efavirenz pharmacokinetics and pharmacogenetics on neuropsychological disorders in Ugandan HIV-positive patients with or without tuberculosis: a prospective cohort study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Generating genome-scale candidate gene lists for pharmacogenomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Pharmacogenomic testing: relevance in medical practice: why drugs work in some patients but not in others

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Integrating large-scale genotype and phenotype data

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Genetic polymorphism of drug metabolising enzymes in African populations: implications for the use of neuroleptics and antidepressants

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Cytochrome p450 and chemical toxicology

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Molecular diversity and population structure at the Cytochrome P450 3A5 gene in Africa

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Update information on drug metabolism systems--2009, part II: summary of information on the effects of diseases and environmental factors on human cytochrome P450 (CYP) enzymes and transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

CTLA-4: new insights into its biological function and use in tumor immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Linkage disequilibrium in human populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Phenotyping and genotyping of S-mephenytoin hydroxylase (cytochrome P450 2C19) in a Shona population of Zimbabwe

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

A novel mutant variant of the CYP2D6 gene (CYP2D6*17) common in a black African population: association with diminished debrisoquine hydroxylase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Phenotype and genotype analysis of debrisoquine hydroxylase (CYP2D6) in a black Zimbabwean population. Reduced enzyme activity and evaluation of metabolic correlation of CYP2D6 probe drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Genetic polymorphism of CYP2D6 and CYP2C19 in east- and southern African populations including psychiatric patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

The molecular and enzyme kinetic basis for the diminished activity of the cytochrome P450 2D6.17 (CYP2D6.17) variant. Potential implications for CYP2D6 phenotyping studies and the clinical use of CYP2D6 substrate drugs in some African populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Patterns of variation influencing antipsychotic treatment outcomes in South African first-episode schizophrenia patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Pharmacogenetics: from bench to byte--an update of guidelines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Cytochrome P450 pharmacogenetics in African populations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Establishment of a biobank and pharmacogenetics database of African populations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Phenotypes and genotypes for CYP2D6 and CYP2C19 in a black Tanzanian population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Bantu Tanzanians have a decreased capacity to metabolize omeprazole and mephenytoin in relation to their CYP2C19 genotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Evidence for environmental influence on CYP2D6-catalysed debrisoquine hydroxylation as demonstrated by phenotyping and genotyping of Ethiopians living in Ethiopia or in Sweden

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Halofantrine and chloroquine inhibit CYP2D6 activity in healthy Zambians

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

The CYP2D6 gene locus in South African Coloureds: unique allele distributions, novel alleles and gene arrangements.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Elucidation of CYP2D6 genetic diversity in a unique African population: implications for the future application of pharmacogenetics in the Xhosa population

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Introduction of the AmpliChip CYP450 Test to a South African cohort: a platform comparative prospective cohort study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

The African-specific CYP2D617 allele encodes an enzyme with changed substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

CYP2D6 genotype and tamoxifen response for breast cancer: a systematic review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

CYP2D6 and CYP2C19 genotype-based dose recommendations for antidepressants: a first step towards subpopulation-specific dosages

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

CYP3A variation and the evolution of salt-sensitivity variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Significant pharmacokinetic interactions between artemether/lumefantrine and efavirenz or nevirapine in HIV-infected Ugandan adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

In vivo analysis of efavirenz metabolism in individuals with impaired CYP2A6 function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

The cytochrome P450 2B6 (CYP2B6) is the main catalyst of efavirenz primary and secondary metabolism: implication for HIV/AIDS therapy and utility of efavirenz as a substrate marker of CYP2B6 catalytic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Genome-wide association study of plasma efavirenz pharmacokinetics in AIDS Clinical Trials Group protocols implicates several CYP2B6 variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

The role of genetic polymorphisms in cytochrome P450 and effects of tuberculosis co-treatment on the predictive value of CYP2B6 SNPs and on efavirenz plasma levels in adult HIV patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Presence of the CYP2B6 516G> T polymorphism, increased plasma Efavirenz concentrations and early neuropsychiatric side effects in South African HIV-infected patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

High predictive value of CYP2B6 SNPs for steady-state plasma efavirenz levels in South African HIV/AIDS patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Pharmacogenetic associations with plasma efavirenz concentrations and clinical correlates in a retrospective cohort of Ghanaian HIV-infected patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Absence seizures associated with efavirenz initiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Population pharmacokinetic/pharmacogenetic model for optimization of efavirenz therapy in Caucasian HIV-infected patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Influence of the cytochrome P450 2B6 genotype on population pharmacokinetics of efavirenz in human immunodeficiency virus patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Efavirenz plasma levels can predict treatment failure and central nervous system side effects in HIV-1-infected patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Novel CYP2C9 genetic variants in Asian subjects and their influence on maintenance warfarin dose

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Functional characterization of novel allelic variants of CYP2C9 recently discovered in southeast Asians

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Influence of CYP2C9 and VKORC1 on warfarin dose, anticoagulation attainment and maintenance among European-Americans and African-Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Combined CYP2C9, VKORC1 and CYP4F2 frequencies among racial and ethnic groups

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Warfarin pharmacogenetics: polymorphisms of the CYP2C9, CYP4F2, and VKORC1 loci in a genetically admixed Omani population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

The next steps for genomic medicine: challenges and opportunities for the developing world.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Biomedical research, a tool to address the health issues that affect African populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Ready to put metadata on the post-2015 development agenda? Linking data publications to responsible innovation and science diplomacy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Toward more transparent and reproducible omics studies through a common metadata checklist and data publications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Frequency of human CYP2D6 mutant alleles in a normal Chinese population

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Allele and genotype frequencies of CYP3A4, CYP2C19, and CYP2D6 in Han, Uighur, Hui, and Mongolian Chinese populations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

CYP2C9 allelic variants: ethnic distribution and functional significance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Single nucleotide polymorphisms and haplotype frequencies of CYP3A5 in a Japanese population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Frequencies of CYP2D6 mutant alleles in a normal Japanese population and metabolic activity of dextromethorphan O-demethylation in different CYP2D6 genotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Allele and genotype frequencies of CYP2C9 in a Korean population

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Discovery of novel functional variants and extensive evaluation of CYP2D6 genetic polymorphisms in Koreans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Analysis of pharmacogenetic traits in two distinct South African populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

CYP3A5 genotypes and risk of oesophageal cancer in two South African populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Frequency of -163 C>A and 63 C>G single nucleotide polymorphism of cytochrome P450 1A2 in two African populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Genetic variants in CYP (-1A2, -2C9, -2C19, -3A4 and -3A5), VKORC1 and ABCB1 genes in a black South African population: a window into diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Pharmacogenomic Research in South Africa: Lessons Learned and Future Opportunities in the Rainbow Nation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Effect of single nucleotide polymorphisms in cytochrome P450 isoenzyme and N-acetyltransferase 2 genes on the metabolism of artemisinin-based combination therapies in malaria patients from Cambodia and Tanzania

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Evolution of detoxifying systems: the role of environment and population history in shaping genetic diversity at human CYP2D6 locus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Incidence of abacavir hypersensitivity and its relationship with HLA-B*5701 in HIV-infected patients in Taiwan

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

CYP1A2, CYP2A6, CYP2B6, CYP3A4 and CYP3A5 Polymorphisms in Two Bantu-Speaking Populations from Cameroon and South Africa: Implications for Global Pharmacogenetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Editorial (An Idea Whose Time Has Come? An African Foresight Observatory on Genomics Medicine and Data-Intensive Global Science)

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

SIMULTANEOUS GENOTYPING OF CYP2D6*3, *4, *5 AND *6 POLYMORPHISMS IN A SPANISH POPULATION THROUGH MULTIPLEX LONG POLYMERASE CHAIN REACTION AND MINISEQUENCING MULTIPLEX SINGLE BASE EXTENSION ANALYSIS

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

Frequencies of Single Nucleotide Polymorphisms in Cytochrome P450 Genes (CYP1A2, 2A6, 2B6, 3A4 and 3A5) in a Rwandan Population: Difference to Other African Populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

African nations vow to support science

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2014.894020

10.1517/17425255.2014.894020

21 January 2018

Identifiers

DOI

1 reference

30 August 2017

1 reference

PubMed ID

24588448