(Q43879115)

English

Genetic variants in CYP (-1A2, -2C9, -2C19, -3A4 and -3A5), VKORC1 and ABCB1 genes in a black South African population: a window into diversity

scientific article published in December 2011

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scholarly article

1 reference

Europe PubMed Central

27 November 2017

Genetic variants in CYP (-1A2, -2C9, -2C19, -3A4 and -3A5), VKORC1 and ABCB1 genes in a black South African population: a window into diversity (English)

1 reference

Europe PubMed Central

27 November 2017

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Europe PubMed Central

27 November 2017

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object named as

Shane A Norris

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Europe PubMed Central

27 November 2017

object named as

Zané Lombard

2

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author name string

Ingrid Du Plooy

3

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Europe PubMed Central

27 November 2017

Tracy McLellan

4

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Europe PubMed Central

27 November 2017

Michèle Ramsay

6

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Europe PubMed Central

27 November 2017

publication date

1 December 2011

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Europe PubMed Central

27 November 2017

Pharmacogenomics

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Europe PubMed Central

27 November 2017

12

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Europe PubMed Central

27 November 2017

12

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Europe PubMed Central

27 November 2017

1663-1670

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Europe PubMed Central

27 November 2017

Adverse drug reactions in adult medical inpatients in a South African hospital serving a community with a high HIV/AIDS prevalence: prospective observational study

1 reference

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21 January 2018

Ethnic differences in pharmacogenetically relevant genes

1 reference

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Designing pharmacogenetic projects in industry: practical design perspectives from the Industry Pharmacogenomics Working Group

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A map of human genome variation from population-scale sequencing

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Integrating common and rare genetic variation in diverse human populations

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Pharmacogenetics: from discovery to patient care

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21 January 2018

Applying the genome to national drug formulary policy in the developing world

1 reference

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21 January 2018

Characterization of the genetic profile of CYP2C19 in two South African populations.

1 reference

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21 January 2018

Elucidation of CYP2D6 genetic diversity in a unique African population: implications for the future application of pharmacogenetics in the Xhosa population

1 reference

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21 January 2018

Pharmacogenomic Research in South Africa: Lessons Learned and Future Opportunities in the Rainbow Nation.

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21 January 2018

Lack of impact of CYP1A2 genetic polymorphism (C/A polymorphism at position 734 in intron 1 and G/A polymorphism at position -2964 in the 5'-flanking region of CYP1A2) on the plasma concentration of haloperidol in smoking male Japanese with schizoph

1 reference

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21 January 2018

Genetic polymorphism of CYP1A2 increases the risk of myocardial infarction.

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21 January 2018

Genetic polymorphism of CYP1A2 and the toxicity of leflunomide treatment in rheumatoid arthritis patients

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DNA sequence variation in a 3.7-kb noncoding sequence 5' of the CYP1A2 gene: implications for human population history and natural selection

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21 January 2018

Frequency of -163 C>A and 63 C>G single nucleotide polymorphism of cytochrome P450 1A2 in two African populations

1 reference

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21 January 2018

A comparison of relative abundance, activity factor and inhibitory monoclonal antibody approaches in the characterization of human CYP enzymology

1 reference

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21 January 2018

Clinical relevance of genetic polymorphisms in the human CYP2C subfamily

1 reference

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21 January 2018

Novel CYP2C9 and VKORC1 gene variants associated with warfarin dosage variability in the South African black population

1 reference

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21 January 2018

Clinical significance of the cytochrome P450 2C19 genetic polymorphism

1 reference

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21 January 2018

CYP3A5 genotype has significant effect on quinine 3-hydroxylation in Tanzanians, who have lower total CYP3A activity than a Swedish population

1 reference

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21 January 2018

Genetic variations in ABCB1 and CYP3A5 as well as sex influence quinine disposition among Ugandans

1 reference

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21 January 2018

Cancer treatment and pharmacogenetics of cytochrome P450 enzymes

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21 January 2018

The structure and functions of P-glycoprotein

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21 January 2018

Host genetic influences on highly active antiretroviral therapy efficacy and AIDS-free survival.

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21 January 2018

Population pharmacokinetic-pharmacogenetic study of nevirapine in HIV-infected Cambodian patients

1 reference

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21 January 2018

CYP3A activity in African American and European American men: population differences and functional effect of the CYP3A4*1B5'-promoter region polymorphism

1 reference

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21 January 2018

The effect of the CYP1A2 *1F mutation on CYP1A2 inducibility in pregnant women

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21 January 2018

Influence of genetic polymorphisms, smoking, gender and age on CYP1A2 activity in a Turkish population.

1 reference

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21 January 2018

Increased transcriptional activity of the CYP3A4*1B promoter variant

1 reference

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21 January 2018

Cohort Profile: Mandela's children: the 1990 Birth to Twenty study in South Africa

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21 January 2018

A simple salting out procedure for extracting DNA from human nucleated cells

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21 January 2018

Interpretation of custom designed Illumina genotype cluster plots for targeted association studies and next-generation sequence validation

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21 January 2018

A second generation human haplotype map of over 3.1 million SNPs

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21 January 2018

Comparative and evolutionary pharmacogenetics of ABCB1: complex signatures of positive selection on coding and regulatory regions.

1 reference

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21 January 2018

Molecular population genetics of human CYP3A locus: signatures of positive selection and implications for evolutionary environmental medicine

1 reference

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21 January 2018

CYP1A2 is more variable than previously thought: a genomic biography of the gene behind the human drug-metabolizing enzyme

1 reference

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21 January 2018

CYP3A variation and the evolution of salt-sensitivity variants

1 reference

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21 January 2018

Analysis of pharmacogenetic traits in two distinct South African populations

1 reference

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21 January 2018

A "silent" polymorphism in the MDR1 gene changes substrate specificity

1 reference

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21 January 2018

Substrate-dependent effects of human ABCB1 coding polymorphisms

1 reference

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21 January 2018

Haplotype analysis of ABCB1/MDR1 blocks in a Japanese population reveals genotype-dependent renal clearance of irinotecan

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Pharmacogenetics and olanzapine treatment: CYP1A2*1F and serotonergic polymorphisms influence therapeutic outcome.

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21 January 2018

Worldwide allele frequency distribution of four polymorphisms associated with warfarin dose requirements.

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21 January 2018

Effect of CYP3A and ABCB1 single nucleotide polymorphisms on the pharmacokinetics and pharmacodynamics of calcineurin inhibitors: Part I.

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21 January 2018

Effect of CYP3A and ABCB1 single nucleotide polymorphisms on the pharmacokinetics and pharmacodynamics of calcineurin inhibitors: Part II.

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21 January 2018

Novel polymorphisms associated with tacrolimus trough concentrations: results from a multicenter kidney transplant consortium

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21 January 2018

Genetic variation of VKORC1 and CYP4F2 genes related to warfarin maintenance dose in patients with myocardial infarction

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A pharmacogenetic study of CD4 recovery in response to HIV antiretroviral therapy in two South African population groups

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21 January 2018

Identifiers

10.2217/PGS.11.106

1 reference

Europe PubMed Central

27 November 2017

1 reference

Europe PubMed Central

27 November 2017

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