(Q38199722)

30 August 2017

title

The deubiquitinase A20 in immunopathology of autoimmune diseases (English)

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30 August 2017

Ishani Majumdar

1

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30 August 2017

Jaishree Paul

series ordinal

2

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30 August 2017

publication date

27 March 2014

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30 August 2017

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30 August 2017

volume

47

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30 August 2017

issue

5

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30 August 2017

page(s)

307-319

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Transcription factor NF-kappaB: a sensor for smoke and stress signals

30 August 2017

cites work

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Regulation of NF-κB signaling by the A20 deubiquitinase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Deubiquitylation and regulation of the immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Expression, biological activities and mechanisms of action of A20 (TNFAIP3).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Structure of the A20 OTU domain and mechanistic insights into deubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Ubiquitin binding to A20 ZnF4 is required for modulation of NF-κB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Ubiquitination of RIP1 regulates an NF-kappaB-independent cell-death switch in TNF signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFalpha)-induced NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Dimerization and ubiquitin mediated recruitment of A20, a complex deubiquitinating enzyme.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

The zinc finger protein A20 targets TRAF2 to the lysosomes for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Inhibition of NF-kappaB signaling by A20 through disruption of ubiquitin enzyme complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Direct, noncatalytic mechanism of IKK inhibition by A20.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

ABIN-1 binds to NEMO/IKKgamma and co-operates with A20 in inhibiting NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

A20 inhibits LUBAC-mediated NF-κB activation by binding linear polyubiquitin chains via its zinc finger 7

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

The cytokine-inducible zinc finger protein A20 inhibits IL-1-induced NF-kappaB activation at the level of TRAF6

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Traf6 and A20 differentially regulate TLR4-induced autophagy by affecting the ubiquitination of Beclin 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Regulation of Toll-like receptor signaling by NDP52-mediated selective autophagy is normally inactivated by A20

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

The immunological and genetic basis of inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

The ubiquitin-editing enzyme A20 restricts nucleotide-binding oligomerization domain containing 2-triggered signals

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

T cell antigen receptor stimulation induces MALT1 paracaspase-mediated cleavage of the NF-kappaB inhibitor A20

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

A20 negatively regulates T cell receptor signaling to NF-kappaB by cleaving Malt1 ubiquitin chains.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

B cells lacking the tumor suppressor TNFAIP3/A20 display impaired differentiation and hyperactivation and cause inflammation and autoimmunity in aged mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

The anaphase-promoting complex protein 5 (AnapC5) associates with A20 and inhibits IL-17-mediated signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

The deubiquitinase A20 mediates feedback inhibition of interleukin-17 receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

IkappaB kinase beta phosphorylates the K63 deubiquitinase A20 to cause feedback inhibition of the NF-kappaB pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

The kinase IKKα inhibits activation of the transcription factor NF-κB by phosphorylating the regulatory molecule TAX1BP1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Enhanced NF-kappaB activation and cellular function in macrophages lacking IkappaB kinase 1 (IKK1).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

NAViGaTing the micronome--using multiple microRNA prediction databases to identify signalling pathway-associated microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

NF-kappaB dysregulation in microRNA-146a-deficient mice drives the development of myeloid malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

miR-301a as an NF-κB activator in pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

miR-486 sustains NF-κB activity by disrupting multiple NF-κB-negative feedback loops.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

A miR-19 regulon that controls NF-κB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

miR-29c targets TNFAIP3, inhibits cell proliferation and induces apoptosis in hepatitis B virus-related hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Regulation of A20 and other OTU deubiquitinases by reversible oxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

The roles of CARMA1, Bcl10, and MALT1 in antigen receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

A20 inhibits NF-kappaB activation independently of binding to 14-3-3 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Sequencing of TNFAIP3 and association of variants with multiple autoimmune diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

African-derived genetic polymorphisms in TNFAIP3 mediate risk for autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Multiple polymorphisms in the TNFAIP3 region are independently associated with systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Rheumatoid arthritis association at 6q23.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Most common single-nucleotide polymorphisms associated with rheumatoid arthritis in persons of European ancestry confer risk of rheumatoid arthritis in African Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Two independent alleles at 6q23 associated with risk of rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Rare variation at the TNFAIP3 locus and susceptibility to rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Analysis of 17 autoimmune disease-associated variants in type 1 diabetes identifies 6q23/TNFAIP3 as a susceptibility locus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Expression of tumor necrosis factor alpha-induced protein 3 mRNA in peripheral blood mononuclear cells negatively correlates with disease severity in psoriasis vulgaris

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Toll-like receptor signalling in the intestinal epithelium: how bacterial recognition shapes intestinal function.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Ubiquitin-editing enzyme A20 promotes tolerance to lipopolysaccharide in enterocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Homeostatic MyD88-dependent signals cause lethal inflamMation in the absence of A20.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor-induced toxicity and experimental colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Role of mucosal dendritic cells in inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Expression of A20 by dendritic cells preserves immune homeostasis and prevents colitis and spondyloarthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Keratinocyte-specific ablation of the NF-κB regulatory protein A20 (TNFAIP3) reveals a role in the control of epidermal homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

The ubiquitin-editing protein A20 prevents dendritic cell activation, recognition of apoptotic cells, and systemic autoimmunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

The ubiquitin modifying enzyme A20 restricts B cell survival and prevents autoimmunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

A pro-inflammatory role for A20 and ABIN family proteins in human fibroblast-like synoviocytes in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Intron-derived aberrant splicing of A20 transcript in rheumatoid arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

ABINs: A20 binding inhibitors of NF-kappa B and apoptosis signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Association of TNFAIP3 interacting protein 1, TNIP1 with systemic lupus erythematosus in a Japanese population: a case-control association study

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Cutting edge: ABIN-1 protects against psoriasis by restricting MyD88 signals in dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

A20-binding inhibitor of NF-κB (ABIN1) controls Toll-like receptor-mediated CCAAT/enhancer-binding protein β activation and protects from inflammatory disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Polyubiquitin binding to ABIN1 is required to prevent autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Inflammatory cardiac valvulitis in TAX1BP1-deficient mice through selective NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Paracaspase MALT1 deficiency protects mice from autoimmune-mediated demyelination

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

MicroRNAs: novel regulators involved in the pathogenesis of psoriasis?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

The miR-17-92 microRNA cluster regulates multiple components of the TGF-β pathway in neuroblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

MiRNA-29: a microRNA family with tumor-suppressing and immune-modulating properties

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Altered expression of miR-17-5p in CD4+ lymphocytes of relapsing-remitting multiple sclerosis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

MicroRNAs miR-17 and miR-20a inhibit T cell activation genes and are under-expressed in MS whole blood

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Tumor necrosis factor receptor-associated factor (TRAF) 2 controls homeostasis of the colon to prevent spontaneous development of murine inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Crucial role for TNF receptor-associated factor 2 (TRAF2) in regulating NFκB2 signaling that contributes to autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Association of RIP2 gene polymorphisms and systemic lupus erythematosus in a Chinese population.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Activation of NOD2-mediated intestinal pathway in a pediatric population with Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Inhibition of RICK/nuclear factor-kappaB and p38 signaling attenuates the inflammatory response in a murine model of Crohn disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Signaling via the RIP2 adaptor protein in central nervous system-infiltrating dendritic cells promotes inflammation and autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

A20: from ubiquitin editing to tumour suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Genetic variation and alterations of genes involved in NFκB/TNFAIP3- and NLRP3-inflammasome signaling affect susceptibility and outcome of colorectal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

A20 restricts wnt signaling in intestinal epithelial cells and suppresses colon carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

TNFAIP3 gene polymorphisms are associated with response to TNF blockade in psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Binding and Functional Comparisons of Two Types of Tumor Necrosis Factor Antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Anti-tumour necrosis factor agents and tuberculosis risk: mechanisms of action and clinical management

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Expression of the autoimmunity associated TNFAIP3 is increased in rheumatoid arthritis but does not differ according to genotype at 6q23

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

IKKα limits macrophage NF-κB activation and contributes to the resolution of inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

Epithelial NEMO links innate immunity to chronic intestinal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08916934.2014.900756

10.3109/08916934.2014.900756

21 January 2018

Identifiers

DOI

1 reference

30 August 2017

1 reference