(Q38244748)

31 August 2017

InTRIMsic immunity: Positive and negative regulation of immune signaling by tripartite motif proteins (English)

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31 August 2017

3

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31 August 2017

Stefan Benke

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Gijs A Versteeg

object named as

Gijs A Versteeg

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1

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Ricardo Rajsbaum

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4

object named as

Ricardo Rajsbaum

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PubMed ID

25172371

31 August 2017

language of work or name

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13 August 2014

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Cytokine and Growth Factor Reviews

31 August 2017

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31 August 2017

25

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31 August 2017

5

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31 August 2017

563-576

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Isolation, genomic organization, and expression analysis of the mouse and rat homologs of MEFV, the gene for familial mediterranean fever

31 August 2017

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12 December 2020

TRIM32 protein modulates type I interferon induction and cellular antiviral response by targeting MITA/STING protein for K63-linked ubiquitination

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12 December 2020

TRAF molecules in cell signaling and in human diseases

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12 December 2020

Pyrin activates the ASC pyroptosome in response to engagement by autoinflammatory PSTPIP1 mutants

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12 December 2020

The NEDD8 pathway is essential for SCF(beta -TrCP)-mediated ubiquitination and processing of the NF-kappa B precursor p105.

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12 December 2020

TRIM family: Pleiotropy and diversification through homomultimer and heteromultimer formation

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12 December 2020

Solution structure of the MID1 B-box2 CHC(D/C)C(2)H(2) zinc-binding domain: insights into an evolutionarily conserved RING fold

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12 December 2020

Ribosomal proteins are targets for the NEDD8 pathway

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12 December 2020

SUMO1 modification of NF-kappaB2/p100 is essential for stimuli-induced p100 phosphorylation and processing

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12 December 2020

Comment on "Gene disruption study reveals a nonredundant role for TRIM21/Ro52 in NF-kappa B-dependent cytokine expression in fibroblasts".

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12 December 2020

TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains

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12 December 2020

TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity

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12 December 2020

Tripartite motif-containing protein 30 modulates TCR-activated proliferation and effector functions in CD4+ T cells

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12 December 2020

Intracellular antibody-bound pathogens stimulate immune signaling via the Fc receptor TRIM21.

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12 December 2020

Cyclophilin A retrotransposition into TRIM5 explains owl monkey resistance to HIV-1

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12 December 2020

The E3-ligase TRIM family of proteins regulates signaling pathways triggered by innate immune pattern-recognition receptors

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12 December 2020

Residual NADPH oxidase and survival in chronic granulomatous disease

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12 December 2020

Loss of the lupus autoantigen Ro52/Trim21 induces tissue inflammation and systemic autoimmunity by disregulating the IL-23-Th17 pathway

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12 December 2020

The E3 ubiquitin ligase TRIM21 negatively regulates the innate immune response to intracellular double-stranded DNA

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12 December 2020

Genomic analysis of the TRIM family reveals two groups of genes with distinct evolutionary properties

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12 December 2020

Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase-mediated antiviral response

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12 December 2020

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5

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12 December 2020

Subclassification of the RBCC/TRIM superfamily reveals a novel motif necessary for microtubule binding

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12 December 2020

The antiviral innate immune response in fish: evolution and conservation of the IFN system.

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12 December 2020

Pattern recognition receptors and inflammation

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12 December 2020

TRIM14 is a mitochondrial adaptor that facilitates retinoic acid-inducible gene-I-like receptor-mediated innate immune response

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12 December 2020

E3 ubiquitin ligase tripartite motif 38 negatively regulates TLR-mediated immune responses by proteasomal degradation of TNF receptor-associated factor 6 in macrophages

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12 December 2020

Identification of a genomic reservoir for new TRIM genes in primate genomes

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12 December 2020

TRIM38 inhibits TNFα- and IL-1β-triggered NF-κB activation by mediating lysosome-dependent degradation of TAB2/3.

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12 December 2020

TRIM27 negatively regulates NOD2 by ubiquitination and proteasomal degradation

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12 December 2020

Viral tricks to grid-lock the type I interferon system

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12 December 2020

Negative feedback regulation of RIG-I-mediated antiviral signaling by interferon-induced ISG15 conjugation

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12 December 2020

Expanding role of ubiquitination in NF-κB signaling

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12 December 2020

Involvement of the rfp tripartite motif in protein-protein interactions and subcellular distribution

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12 December 2020

Immunomodulatory functions of type I interferons

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12 December 2020

Ubiquitin-induced oligomerization of the RNA sensors RIG-I and MDA5 activates antiviral innate immune response

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12 December 2020

Genomics and evolution of the TRIM gene family

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12 December 2020

Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3

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12 December 2020

The interferon-inducible ubiquitin-protein isopeptide ligase (E3) EFP also functions as an ISG15 E3 ligase

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12 December 2020

Specific recognition and accelerated uncoating of retroviral capsids by the TRIM5alpha restriction factor

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12 December 2020

SUMO conjugation of STAT1 protects cells from hyperresponsiveness to IFNγ.

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12 December 2020

In vivo ligands of MDA5 and RIG-I in measles virus-infected cells

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12 December 2020

The evolution of mammalian gene families

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12 December 2020

The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1beta production

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12 December 2020

Type I IFN signaling is crucial for host resistance against different species of pathogenic bacteria

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12 December 2020

Ubiquitin-binding domains

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12 December 2020

A targeted proteomic analysis of the ubiquitin-like modifier nedd8 and associated proteins.

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12 December 2020

UbcH8 regulates ubiquitin and ISG15 conjugation to RIG-I.

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12 December 2020

Distinct evolution process among type I interferon in mammals

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12 December 2020

Expansion and molecular evolution of the interferon-induced 2'-5' oligoadenylate synthetase gene family

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12 December 2020

Role and fate of PML nuclear bodies in response to interferon and viral infections

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12 December 2020

Structural basis for ubiquitin-mediated antiviral signal activation by RIG-I

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12 December 2020

Type I interferon-dependent and -independent expression of tripartite motif proteins in immune cells.

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12 December 2020

TRIM21 is essential to sustain IFN regulatory factor 3 activation during antiviral response

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12 December 2020

Trim5alpha protein restricts both HIV-1 and murine leukemia virus

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12 December 2020

Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity

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12 December 2020

The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology

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12 December 2020

Origin and evolution of TRIM proteins: new insights from the complete TRIM repertoire of zebrafish and pufferfish

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12 December 2020

Multiple functions of the IKK-related kinase IKKepsilon in interferon-mediated antiviral immunity

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12 December 2020

Viral evasion mechanisms of early antiviral responses involving regulation of ubiquitin pathways

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12 December 2020

The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells

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12 December 2020

Tripartite-motif protein 30 negatively regulates NLRP3 inflammasome activation by modulating reactive oxygen species production

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12 December 2020

The E3 ubiquitin ligase Ro52 negatively regulates IFN-beta production post-pathogen recognition by polyubiquitin-mediated degradation of IRF3

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12 December 2020

TRIM5α associates with proteasomal subunits in cells while in complex with HIV-1 virions

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12 December 2020

Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis

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12 December 2020

TRIM21 is an IgG receptor that is structurally, thermodynamically, and kinetically conserved

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12 December 2020

Functional characterization of the Opitz syndrome gene product (midin): evidence for homodimerization and association with microtubules throughout the cell cycle

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12 December 2020

IκB kinase epsilon (IKK(epsilon)) regulates the balance between type I and type II interferon responses

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12 December 2020

Comparative genomic analysis of the interferon/interleukin-10 receptor gene cluster

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12 December 2020

Structural basis for dsRNA recognition, filament formation, and antiviral signal activation by MDA5

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12 December 2020

Are the IKKs and IKK-related kinases TBK1 and IKK-epsilon similarly activated?

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12 December 2020

Tripartite motif-containing protein 38 negatively regulates TLR3/4- and RIG-I-mediated IFN-β production and antiviral response by targeting NAP1

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12 December 2020

Inflammation meets cancer, with NF-κB as the matchmaker

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12 December 2020

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

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12 December 2020

HECT and RING finger families of E3 ubiquitin ligases at a glance

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12 December 2020

14-3-3 proteins sequester a pool of soluble TRIM32 ubiquitin ligase to repress autoubiquitylation and cytoplasmic body formation.

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12 December 2020

TRIM30 alpha negatively regulates TLR-mediated NF-kappa B activation by targeting TAB2 and TAB3 for degradation

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12 December 2020

Gene disruption study reveals a nonredundant role for TRIM21/Ro52 in NF-kappaB-dependent cytokine expression in fibroblasts

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12 December 2020

Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium

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12 December 2020

A single amino acid change in the SPRY domain of human Trim5alpha leads to HIV-1 restriction

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12 December 2020

Novel function of Trim44 promotes an antiviral response by stabilizing VISA.

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12 December 2020

The role of dendritic cells in autoimmunity

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12 December 2020

Antiviral TRIMs: friend or foe in autoimmune and autoinflammatory disease?

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12 December 2020

TRIM16 acts as an E3 ubiquitin ligase and can heterodimerize with other TRIM family members

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12 December 2020

Interferon-induced Ifit2/ISG54 protects mice from lethal VSV neuropathogenesis

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12 December 2020

Human TRIM gene expression in response to interferons

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12 December 2020

Intracellular antibody receptor TRIM21 prevents fatal viral infection

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12 December 2020

The GATA2 transcriptional network is requisite for RAS oncogene-driven non-small cell lung cancer

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12 December 2020

Mechanisms of type-I- and type-II-interferon-mediated signalling

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12 December 2020

Evolution of vertebrate interferon inducible transmembrane proteins

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12 December 2020

Fates of retroviral core components during unrestricted and TRIM5-restricted infection

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12 December 2020

Regulation of type I interferon responses

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12 December 2020

MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascades

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12 December 2020

Implication of PMLIV in both intrinsic and innate immunity

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12 December 2020

Species-specific inhibition of RIG-I ubiquitination and IFN induction by the influenza A virus NS1 protein

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12 December 2020

TRIM family proteins: retroviral restriction and antiviral defence

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12 December 2020

TRIM28 prevents autoinflammatory T cell development in vivo.

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12 December 2020

Polyubiquitin conjugation to NEMO by triparite motif protein 23 (TRIM23) is critical in antiviral defense

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12 December 2020

TRIM5 is an innate immune sensor for the retrovirus capsid lattice

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12 December 2020

Mechanisms and functions of inflammasomes

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12 December 2020

Genetic loss of murine pyrin, the Familial Mediterranean Fever protein, increases interleukin-1β levels

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12 December 2020

Activation and regulation of the inflammasomes

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12 December 2020

Evolutionary genetic dissection of human interferons

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12 December 2020

TRIMmunity: the roles of the TRIM E3-ubiquitin ligase family in innate antiviral immunity

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12 December 2020

TRIM4 modulates type I interferon induction and cellular antiviral response by targeting RIG-I for K63-linked ubiquitination

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12 December 2020

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

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12 December 2020

Global analysis of SUMO chain function reveals multiple roles in chromatin regulation

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12 December 2020

Gain-of-function Pyrin mutations induce NLRP3 protein-independent interleukin-1β activation and severe autoinflammation in mice

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12 December 2020

TRIM proteins and cancer.

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12 December 2020

Interferon-lambdas: the modulators of antivirus, antitumor, and immune responses

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12 December 2020

PML control of cytokine signaling.

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12 December 2020

Self protection from anti-viral responses--Ro52 promotes degradation of the transcription factor IRF7 downstream of the viral Toll-Like receptors

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12 December 2020

5'-Triphosphate RNA is the ligand for RIG-I

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12 December 2020

RING domain mutations uncouple TRIM5α restriction of HIV-1 from inhibition of reverse transcription and acceleration of uncoating

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12 December 2020

The tripartite motif family identifies cell compartments

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12 December 2020

Independent evolution of an antiviral TRIMCyp in rhesus macaques

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12 December 2020

TRIM protein-mediated regulation of inflammatory and innate immune signaling and its association with antiretroviral activity

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12 December 2020

Tripartite motif containing protein 27 negatively regulates CD4 T cells by ubiquitinating and inhibiting the class II PI3K-C2β

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12 December 2020

Ubiquitin-binding proteins: decoders of ubiquitin-mediated cellular functions

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12 December 2020

Evolution of innate and adaptive immunity: can we draw a line?

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12 December 2020

The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response

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12 December 2020

A large new subset of TRIM genes highly diversified by duplication and positive selection in teleost fish

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12 December 2020

The ubiquitin ligase Riplet is essential for RIG-I-dependent innate immune responses to RNA virus infection.

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12 December 2020

The ubiquitin ligase TRIM56 regulates innate immune responses to intracellular double-stranded DNA

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12 December 2020

The inflammasomes: mechanisms of activation and function

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12 December 2020

MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response

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12 December 2020

Dynamic evolution of immune system regulators: the history of the interferon regulatory factor family

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12 December 2020

10.1016/J.CYTOGFR.2014.08.001

Identifiers

DOI

1 reference

31 August 2017

0 references

1 reference

PubMed ID

25172371