(Q38245433)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25179911%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

title

The mitochondrial permeability transition: a current perspective on its identity and role in ischaemia/reperfusion injury (English)

1 reference

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15 February 2020

1 reference

1

1 reference

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15 February 2020

author name string

Andrew P Richardson

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25179911%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

publication date

30 August 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25179911%20AND%20SRC:MED&resulttype=core&format=json

Journal of Molecular and Cellular Cardiology

15 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25179911%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

volume

78

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25179911%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

page(s)

129-141

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25179911%20AND%20SRC:MED&resulttype=core&format=json

What is the mitochondrial permeability transition pore?

15 February 2020

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7 January 2021

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7 January 2021

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Cyclophilin D modulates mitochondrial F0F1-ATP synthase by interacting with the lateral stalk of the complex

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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The mitochondrial megachannel is the permeability transition pore

7 January 2021

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Electrophysiology clarifies the megariddles of the mitochondrial permeability transition pore

7 January 2021

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7 January 2021

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Regulation of the inner membrane mitochondrial permeability transition by the outer membrane translocator protein (peripheral benzodiazepine receptor)

7 January 2021

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The permeability transition pore opening in intact mitochondria and submitochondrial particles.

7 January 2021

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Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell death

7 January 2021

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Regulation of the mitochondrial permeability transition pore by the outer membrane does not involve the peripheral benzodiazepine receptor (Translocator Protein of 18 kDa (TSPO)).

7 January 2021

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Hexokinase II: the integration of energy metabolism and control of apoptosis

7 January 2021

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Bcl-2 does not inhibit the permeability transition pore in mouse liver mitochondria

7 January 2021

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Bax regulates primary necrosis through mitochondrial dynamics

7 January 2021

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Bax and Bak function as the outer membrane component of the mitochondrial permeability pore in regulating necrotic cell death in mice

7 January 2021

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Hexokinase-2 bound to mitochondria: cancer's stygian link to the "Warburg Effect" and a pivotal target for effective therapy

7 January 2021

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Mitochondrial hexokinases: guardians of the mitochondria

7 January 2021

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Extent of mitochondrial hexokinase II dissociation during ischemia correlates with mitochondrial cytochrome c release, reactive oxygen species production, and infarct size on reperfusion

7 January 2021

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Targeting hexokinase II to mitochondria to modulate energy metabolism and reduce ischaemia-reperfusion injury in heart

7 January 2021

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Mitochondrial contact sites: their role in energy metabolism and apoptosis

7 January 2021

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Complexes between porin, hexokinase, mitochondrial creatine kinase and adenylate translocator display properties of the permeability transition pore. Implication for regulation of permeability transition by the kinases

7 January 2021

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CKMT1 regulates the mitochondrial permeability transition pore in a process that provides evidence for alternative forms of the complex.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Cyclosporin A binding to mitochondrial cyclophilin inhibits the permeability transition pore and protects hearts from ischaemia/reperfusion injury

7 January 2021

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Protection by Cyclosporin A of ischemia/reperfusion-induced damage in isolated rat hearts.

7 January 2021

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On the involvement of a cyclosporin A sensitive mitochondrial pore in myocardial reperfusion injury

7 January 2021

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Specific inhibition of the mitochondrial permeability transition prevents lethal reperfusion injury

7 January 2021

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Cinnamic anilides as new mitochondrial permeability transition pore inhibitors endowed with ischemia-reperfusion injury protective effect in vivo

7 January 2021

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The physiological role of mitochondrial calcium revealed by mice lacking the mitochondrial calcium uniporter.

7 January 2021

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Ionic basis of ischaemic cardiac injury: insights from cellular studies

7 January 2021

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Changes in mitochondrial matrix free calcium in perfused rat hearts subjected to hypoxia-reoxygenation.

7 January 2021

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Mitochondrial calcium transport in the heart: physiological and pathological roles

7 January 2021

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Inhibiting mitochondrial permeability transition pore opening at reperfusion protects against ischaemia-reperfusion injury

7 January 2021

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Cyclosporine A at reperfusion fails to reduce infarct size in the in vivo rat heart

7 January 2021

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7 January 2021

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NHE-1 inhibition-induced cardioprotection against ischaemia/reperfusion is associated with attenuation of the mitochondrial permeability transition

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

The pH hypothesis of postconditioning: staccato reperfusion reintroduces oxygen and perpetuates myocardial acidosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Mitochondrial permeability transition pore and postconditioning

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Targeting an antioxidant to mitochondria decreases cardiac ischemia-reperfusion injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Cell-permeable peptide antioxidants targeted to inner mitochondrial membrane inhibit mitochondrial swelling, oxidative cell death, and reperfusion injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Mitochondria-targeted cytoprotective peptides for ischemia-reperfusion injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Protection of hearts from reperfusion injury by propofol is associated with inhibition of the mitochondrial permeability transition.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Propofol is cardioprotective in a clinically relevant model of normothermic blood cardioplegic arrest and cardiopulmonary bypass

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Metabolic cardioprotection by pyruvate: recent progress.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Preconditioning delays Ca2+-induced mitochondrial permeability transition

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

The role of mitochondria in protection of the heart by preconditioning.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Preconditioning: the mitochondrial connection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Mechanism of cardioprotection by early ischemic preconditioning

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

The mitochondrial K(ATP) channel--fact or fiction?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Cardioprotection techniques: preconditioning, postconditioning and remote conditioning (basic science).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Temperature preconditioning of isolated rat hearts--a potent cardioprotective mechanism involving a reduction in oxidative stress and inhibition of the mitochondrial permeability transition pore

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

The role of oxidized cytochrome c in regulating mitochondrial reactive oxygen species production and its perturbation in ischaemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Release of mitochondrial cytochrome c and activation of cytosolic caspases induced by myocardial ischaemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Mitochondria and cell death: outer membrane permeabilization and beyond

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Disruption of hexokinase II-mitochondrial binding blocks ischemic preconditioning and causes rapid cardiac necrosis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Ischemic preconditioning affects hexokinase activity and HKII in different subcellular compartments throughout cardiac ischemia-reperfusion.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Hexokinase II and reperfusion injury: TAT-HK2 peptide impairs vascular function in Langendorff-perfused rat hearts.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Pathophysiological consequences of TAT-HKII peptide administration are independent of impaired vascular function and ensuing ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Is a high glycogen content beneficial or detrimental to the ischemic rat heart? A controversy resolved

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Survival kinases in ischemic preconditioning and postconditioning.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Akt inhibition promotes hexokinase 2 redistribution and glucose uptake in cancer cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Activation of glycogen synthase kinase 3beta disrupts the binding of hexokinase II to mitochondria by phosphorylating voltage-dependent anion channel and potentiates chemotherapy-induced cytotoxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Akt mediates mitochondrial protection in cardiomyocytes through phosphorylation of mitochondrial hexokinase-II.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Akt phosphorylates HK-II at Thr-473 and increases mitochondrial HK-II association to protect cardiomyocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Mitochondrial binding of hexokinase II inhibits Bax-induced cytochrome c release and apoptosis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Hexokinase-mitochondria interaction mediated by Akt is required to inhibit apoptosis in the presence or absence of Bax and Bak

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Contact sites between mitochondrial envelope membranes. Structure and function in energy- and protein-transfer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Changes in freeze-fractured mitochondrial membranes correlated to their energetic state. Dynamic interactions of the boundary membranes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Location and regulation of octameric mitochondrial creatine kinase in the contact sites

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Octameric mitochondrial creatine kinase induces and stabilizes contact sites between the inner and outer membrane

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Inhibition of the mitochondrial permeability transition by creatine kinase substrates. Requirement for microcompartmentation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

TRO40303, a new cardioprotective compound, inhibits mitochondrial permeability transition.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Mitochondrial creatine kinase in contact sites: interaction with porin and adenine nucleotide translocase, role in permeability transition and sensitivity to oxidative damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Alteration of the cytosolic-mitochondrial distribution of high-energy phosphates during global myocardial ischemia may contribute to early contractile failure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Cardioprotection by ischemic preconditioning preserves mitochondrial function and functional coupling between adenine nucleotide translocase and creatine kinase.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Inhibition of mitochondrial permeability transition pore opening: translation to patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Myocardial ischemia-reperfusion injury: a neglected therapeutic target.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Consecutive pharmacological activation of PKA and PKC mimics the potent cardioprotection of temperature preconditioning

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Clinically-relevant consecutive treatment with isoproterenol and adenosine protects the failing heart against ischaemia and reperfusion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Arrangement of subunits in intact mammalian mitochondrial ATP synthase determined by cryo-EM.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

Purification and N-terminal sequencing of peptidyl-prolyl cis-trans-isomerase from rat liver mitochondrial matrix reveals the existence of a distinct mitochondrial cyclophilin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2014.08.018

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.YJMCC.2014.08.018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25179911%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1 reference