(Q38248883)

1 September 2017

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title

Prion-like mechanisms in the pathogenesis of tauopathies and synucleinopathies (English)

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1 September 2017

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4

Markus Tolnay

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author name string

Michel Goedert

1

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1 September 2017

Ben Falcon

2

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1 September 2017

Florence Clavaguera

3

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1 September 2017

Markus Tolnay

4

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1 September 2017

publication date

1 November 2014

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Current Neurology and Neuroscience Reports

1 September 2017

published in

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1 September 2017

volume

14

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1 September 2017

issue

11

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1 September 2017

page(s)

495

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https://scigraph.springernature.com/pub.10.1007/s11910-014-0495-z

1 September 2017

exact match

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cites work

Tau pathology and neurodegeneration

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

100 years of Lewy pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

The propagation of prion-like protein inclusions in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Biology and genetics of prions causing neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Anatomical correlates of the distribution of the pathological changes in the neocortex in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Axonal and transneuronal transport in the transmission of neurological disease: potential role in system degenerations, including Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Electron microscopic evidence for a transsynaptic migration of tetanus toxin in spinal cord motoneurons: An autoradiographic and morphometric study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Selective retrograde transsynaptic transfer of a protein, tetanus toxin, subsequent to its retrograde axonal transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Neurodegenerative diseases target large-scale human brain networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Mouse models for studying the formation and propagation of prions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Neuropathological stageing of Alzheimer-related changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Biopsy-derived adult human brain tau is phosphorylated at many of the same sites as Alzheimer's disease paired helical filament tau.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Imaging of tau pathology in a tauopathy mouse model and in Alzheimer patients compared to normal controls

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Non-invasive assessment of Alzheimer's disease neurofibrillary pathology using 18F-THK5105 PET.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Quantitative analysis of neurofibrillary pathology in a general population to reappraise neuropathological criteria for senile dementia of the neurofibrillary tangle type (tangle-only dementia): the Hisayama Study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Abnormal Tau proteins in progressive supranuclear palsy. Similarities and differences with the neurofibrillary degeneration of the Alzheimer type.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Argyrophilic grain disease is a sporadic 4-repeat tauopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Abnormal tau-containing filaments in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Transmission and spreading of tauopathy in transgenic mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Seeding of normal Tau by pathological Tau conformers drives pathogenesis of Alzheimer-like tangles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

"Prion-like" templated misfolding in tauopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

A novel in vivo model of tau propagation with rapid and progressive neurofibrillary tangle pathology: the pattern of spread is determined by connectivity, not proximity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Trans-synaptic spread of tau pathology in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Propagation of tau pathology in a model of early Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Peripheral administration of tau aggregates triggers intracerebral tauopathy in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

In vivo microdialysis reveals age-dependent decrease of brain interstitial fluid tau levels in P301S human tau transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Physiological release of endogenous tau is stimulated by neuronal activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Neuronal activity regulates extracellular tau in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Propagation of tau misfolding from the outside to the inside of a cell.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Trans-cellular propagation of Tau aggregation by fibrillar species

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Cellular self-defense: how cell-autonomous immunity protects against pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Neurofibrillary tangle-like tau pathology induced by synthetic tau fibrils in primary neurons over-expressing mutant tau.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Seeded aggregation and toxicity of {alpha}-synuclein and tau: cellular models of neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Extracellular tau promotes intracellular calcium increase through M1 and M3 muscarinic receptors in neuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Paired helical filaments from Alzheimer disease brain induce intracellular accumulation of Tau protein in aggresomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Conformational features of tau fibrils from Alzheimer's disease brain are faithfully propagated by unmodified recombinant protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Design and construction of diverse mammalian prion strains

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Brain homogenates from human tauopathies induce tau inclusions in mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Alpha-synuclein in Lewy bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Alpha-synuclein immunoreactivity in glial cytoplasmic inclusions in multiple system atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Glial cytoplasmic inclusions in white matter oligodendrocytes of multiple system atrophy brains contain insoluble alpha-synuclein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

alpha-Synuclein locus triplication causes Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Alpha-synuclein p.H50Q, a novel pathogenic mutation for Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

A novel α-synuclein missense mutation in Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

α-Synucleinopathy associated with G51D SNCA mutation: a link between Parkinson's disease and multiple system atrophy?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

G51D α-synuclein mutation causes a novel parkinsonian-pyramidal syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Genome-wide association study reveals genetic risk underlying Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

SNCA variants are associated with increased risk for multiple system atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Genetic variants of the alpha-synuclein gene SNCA are associated with multiple system atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Staging of brain pathology related to sporadic Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Premotor Parkinson's disease: concepts and definitions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Gastric alpha-synuclein immunoreactive inclusions in Meissner's and Auerbach's plexuses in cases staged for Parkinson's disease-related brain pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Parkinson's disease: a dual-hit hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Multi-organ distribution of phosphorylated alpha-synuclein histopathology in subjects with Lewy body disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Alpha-synuclein pathology in the spinal cords of neurologically asymptomatic aged individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Alpha-synuclein pathology of the spinal and peripheral autonomic nervous system in neurologically unimpaired elderly subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Spinal cord lesions in sporadic Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Transfer of host-derived α synuclein to grafted dopaminergic neurons in rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Alpha-synuclein cell-to-cell transfer and seeding in grafted dopaminergic neurons in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Prion-like acceleration of a synucleinopathy in a transgenic mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Transmission of multiple system atrophy prions to transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Pathological α-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Amyloidogenic α-synuclein seeds do not invariably induce rapid, widespread pathology in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Prion-like spreading of pathological α-synuclein in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Assembly-dependent endocytosis and clearance of extracellular alpha-synuclein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Exogenous alpha-synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Extracellular α--synuclein-a novel and crucial factor in Lewy body diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Different species of alpha-synuclein oligomers induce calcium influx and seeding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Neuron-released oligomeric α-synuclein is an endogenous agonist of TLR2 for paracrine activation of microglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Extracellular alpha-synuclein oligomers modulate synaptic transmission and impair LTP via NMDA-receptor activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Exogenous α-synuclein fibrils induce Lewy body pathology leading to synaptic dysfunction and neuron death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Molecular-level secondary structure, polymorphism, and dynamics of full-length alpha-synuclein fibrils studied by solid-state NMR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Structural and functional characterization of two alpha-synuclein strains

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Concurrence of alpha-synuclein and tau brain pathology in the Contursi kindred

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

The E46K mutation in alpha-synuclein increases amyloid fibril formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Initiation and Synergistic Fibrillization of Tau and Alpha-Synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Distinct α-synuclein strains differentially promote tau inclusions in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Direct observation of the interconversion of normal and toxic forms of α-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Antibody-aided clearance of extracellular α-synuclein prevents cell-to-cell aggregate transmission

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Anti-tau antibodies that block tau aggregate seeding in vitro markedly decrease pathology and improve cognition in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Distinctive neuropathology revealed by α-synuclein antibodies in hereditary parkinsonism and dementia linked to chromosome 4p

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11910-014-0495-Z

Parkinson's disease: lesions in dorsal horn layer I, involvement of parasympathetic and sympathetic pre- and postganglionic neurons

21 January 2018

1 reference

12 December 2020

Membrane-associated heparan sulfate proteoglycan is a receptor for adeno-associated virus type 2 virions

1 reference

12 December 2020

Axonopathy and amyotrophy in mice transgenic for human four-repeat tau protein

1 reference

12 December 2020

Tau isoform profile and phosphorylation state in dementia pugilistica recapitulate Alzheimer's disease

1 reference

12 December 2020

Early clinical PET imaging results with the novel PHF-tau radioligand [F18]-T808.

1 reference

12 December 2020

Non-classical exocytosis of alpha-synuclein is sensitive to folding states and promoted under stress conditions

1 reference

12 December 2020

Staging of argyrophilic grains: an age-associated tauopathy

1 reference

12 December 2020

Transmission of the Virus of Herpes Febrilis along Nerves in experimentally infected Rabbits.

1 reference

12 December 2020

Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau

1 reference

12 December 2020

Novel α-synuclein mutation A53E associated with atypical multiple system atrophy and Parkinson's disease-type pathology

1 reference

12 December 2020

Is alpha-synuclein in the colon a biomarker for premotor Parkinson's disease? Evidence from 3 cases

1 reference

12 December 2020

Argyrophilic grain disease and Alzheimer's disease are distinguished by their different distribution of tau protein isoforms

1 reference

12 December 2020

Specific pathological Tau protein variants characterize Pick's disease.

1 reference

12 December 2020

Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein.

1 reference

12 December 2020

Ultrastructure and biochemical composition of paired helical filaments in corticobasal degeneration

1 reference

12 December 2020

The pathological process underlying Alzheimer's disease in individuals under thirty

1 reference

12 December 2020

Prion-like mechanisms in neurodegenerative diseases

1 reference

12 December 2020

Expression of separate isoforms of human tau protein: correlation with the tau pattern in brain and effects on tubulin polymerization

1 reference

12 December 2020

10.1007/S11910-014-0495-Z

Identifiers

DOI

1 reference

Dimensions Publication ID

1 September 2017

1003460490

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1 reference