(Q38253505)

1 September 2017

1 reference

title

E proteins in lymphocyte development and lymphoid diseases (English)

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1 September 2017

Ian Belle

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6504980&resulttype=core&format=json

14 May 2020

Yuan Zhuang

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6504980&resulttype=core&format=json

14 May 2020

publication date

1 January 2014

1 reference

25248476

Current Topics in Developmental Biology

1 September 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6504980&resulttype=core&format=json

14 May 2020

volume

110

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6504980&resulttype=core&format=json

14 May 2020

page(s)

153-187

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6504980&resulttype=core&format=json

Disruption of alpha beta but not of gamma delta T cell development by overexpression of the helix-loop-helix protein Id3 in committed T cell progenitors

14 May 2020

cites work

1 reference

12 December 2020

A conserved motif present in a class of helix-loop-helix proteins activates transcription by direct recruitment of the SAGA complex

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12 December 2020

Coordinate regulation of RAG1 and RAG2 by cell type-specific DNA elements 5' of RAG2

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12 December 2020

Impaired immune responses and B-cell proliferation in mice lacking the Id3 gene

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12 December 2020

Oncogenic homeodomain transcription factor E2A-Pbx1 activates a novel WNT gene in pre-B acute lymphoblastoid leukemia

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12 December 2020

Commitment to the B-lymphoid lineage depends on the transcription factor Pax5

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12 December 2020

E2A activity is induced during B-cell activation to promote immunoglobulin class switch recombination

1 reference

12 December 2020

mAngiogenin-3, a target gene of oncoprotein E2a-Pbx1, encodes a new angiogenic member of the angiogenin family

1 reference

12 December 2020

Thymocyte selection is regulated by the helix-loop-helix inhibitor protein, Id3.

1 reference

12 December 2020

The PI3K-PDK1 connection: more than just a road to PKB

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12 December 2020

E2A and EBF act in synergy with the V(D)J recombinase to generate a diverse immunoglobulin repertoire in nonlymphoid cells

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12 December 2020

Wnt signaling and cancer

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12 December 2020

Burkitt's lymphoma: molecular pathogenesis and treatment

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12 December 2020

Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism

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12 December 2020

Functions of E2A-HEB heterodimers in T-cell development revealed by a dominant negative mutation of HEB

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12 December 2020

Branching out to gain control: how the pre-TCR is linked to multiple functions

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12 December 2020

BCAP: the tyrosine kinase substrate that connects B cell receptor to phosphoinositide 3-kinase activation

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12 December 2020

Regulation of the helix-loop-helix proteins, E2A and Id3, by the Ras-ERK MAPK cascade

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12 December 2020

B cell development pathways

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12 December 2020

SCL and LMO1 alter thymocyte differentiation: inhibition of E2A-HEB function and pre-T alpha chain expression

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12 December 2020

Induction of a diverse T cell receptor gamma/delta repertoire by the helix-loop-helix proteins E2A and HEB in nonlymphoid cells

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12 December 2020

Signaling through the B cell antigen receptor in developing B cells

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12 December 2020

Strain-specific TCR repertoire selection of IL-4-producing Thy-1dull γ δ thymocytes

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12 December 2020

Promotion of cell cycle progression by basic helix-loop-helix E2A

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12 December 2020

Localized gene-specific induction of accessibility to V(D)J recombination induced by E2A and early B cell factor in nonlymphoid cells

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12 December 2020

Early thymocyte development is regulated by modulation of E2A protein activity

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12 December 2020

Basic helix-loop-helix proteins E2A and HEB induce immature T-cell receptor rearrangements in nonlymphoid cells.

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12 December 2020

Requirement for CD28 co-stimulation is lower in SHP-1-deficient T cells

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12 December 2020

Living with lethal PIP3 levels: viability of flies lacking PTEN restored by a PH domain mutation in Akt/PKB.

1 reference

12 December 2020

Failure of HY-Specific Thymocytes to Escape Negative Selection by Receptor Editing

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12 December 2020

The Th1/Th2 cytokine balance changes with the progress of the immunopathological lesion of Sjogren's syndrome

1 reference

12 December 2020

TH2 dominance and defective development of a CD8+ dendritic cell subset in Id2-deficient mice

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12 December 2020

PI3K in lymphocyte development, differentiation and activation

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12 December 2020

E-proteins directly regulate expression of activation-induced deaminase in mature B cells

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12 December 2020

The Wnt pathway, cell-cycle activation and beta-amyloid: novel therapeutic strategies in Alzheimer's disease?

1 reference

12 December 2020

Gene segment selection in V(D)J recombination: accessibility and beyond

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12 December 2020

A conserved transcriptional enhancer regulates RAG gene expression in developing B cells.

1 reference

12 December 2020

HEB, a Helix-Loop-Helix Protein Related to E2A and ITF2 That Can Modulate the DNA-Binding Ability of Myogenic Regulatory Factors

1 reference

12 December 2020

SJOEGREN'S SYNDROME. A CLINICAL, PATHOLOGICAL, AND SEROLOGICAL STUDY OF SIXTY-TWO CASES

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12 December 2020

Critical Role for CXCR4 Signaling in Progenitor Localization and T Cell Differentiation in the Postnatal Thymus

1 reference

12 December 2020

Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1

1 reference

12 December 2020

Pax5 induces V-to-DJ rearrangements and locus contraction of the immunoglobulin heavy-chain gene

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12 December 2020

Circulating cytokines in primary Sjögren's syndrome determined by a multiplex cytokine array system

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12 December 2020

Differential functions for the transcription factor E2A in positive and negative gene regulation in pre-B lymphocytes

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12 December 2020

A T cell intrinsic role of Id3 in a mouse model for primary Sjogren's syndrome.

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12 December 2020

Visualization of looping involving the immunoglobulin heavy-chain locus in developing B cells

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12 December 2020

E2A and IRF-4/Pip promote chromatin modification and transcription of the immunoglobulin kappa locus in pre-B cells

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12 December 2020

The basic helix-loop-helix transcription factor HEBAlt is expressed in pro-T cells and enhances the generation of T cell precursors

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12 December 2020

Overexpression of E2A proteins induces epithelial-mesenchymal transition in human renal proximal tubular epithelial cells suggesting a potential role in renal fibrosis.

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12 December 2020

E2A promotes the survival of precursor and mature B lymphocytes

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12 December 2020

Mining the Wnt pathway for cancer therapeutics

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12 December 2020

Helix-loop-helix transcription factor E47 activates germ-line immunoglobulin heavy-chain gene transcription and rearrangement in a pre-T-cell line

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12 December 2020

Genome-wide identification of novel genes involved in early Th1 and Th2 cell differentiation

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12 December 2020

Mature natural killer cell and lymphoid tissue-inducing cell development requires Id2-mediated suppression of E protein activity

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12 December 2020

B-lymphocyte depletion ameliorates Sjögren's syndrome in Id3 knockout mice

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12 December 2020

Myc dynamically and preferentially relocates to a transcription factory occupied by Igh

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12 December 2020

Acquisition of a functional T cell receptor during T lymphocyte development is enforced by HEB and E2A transcription factors

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12 December 2020

An inhibitory domain of E12 transcription factor prevents DNA binding in E12 homodimers but not in E12 heterodimers

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12 December 2020

Initiation of allelic exclusion by stochastic interaction of Tcrb alleles with repressive nuclear compartments

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12 December 2020

Instructive role of the transcription factor E2A in early B lymphopoiesis and germinal center B cell development

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12 December 2020

E2A proteins promote development of lymphoid-primed multipotent progenitors

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12 December 2020

E proteins are required to activate germline transcription of the TCR Vbeta8.2 gene

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12 December 2020

Ebf1-mediated down-regulation of Id2 and Id3 is essential for specification of the B cell lineage

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12 December 2020

Id proteins Id1 and Id2 selectively inhibit DNA binding by one class of helix-loop-helix proteins

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12 December 2020

Id3 restricts the developmental potential of gamma delta lineage during thymopoiesis

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12 December 2020

Inhibitor of DNA binding 3 limits development of murine slam-associated adaptor protein-dependent "innate" gammadelta T cells.

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12 December 2020

Early B cell factor 1 regulates B cell gene networks by activation, repression, and transcription- independent poising of chromatin

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12 December 2020

A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate

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12 December 2020

Mutation of inhibitory helix-loop-helix protein Id3 causes γδ T-cell lymphoma in mice.

1 reference

12 December 2020

Modeling Sjögren's syndrome with Id3 conditional knockout mice

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12 December 2020

Two distinct transcription factors that bind the immunoglobulin enhancer microE5/kappa 2 motif

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12 December 2020

The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation

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12 December 2020

The protein Id: a negative regulator of helix-loop-helix DNA binding proteins

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12 December 2020

Genomic loss of the putative tumor suppressor gene E2A in human lymphoma.

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12 December 2020

The opposing roles of the transcription factor E2A and its antagonist Id3 that orchestrate and enforce the naive fate of T cells.

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12 December 2020

Contribution of IL-13 to early exocrinopathy in Id3-/- mice

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12 December 2020

Repression of the DNA-binding inhibitor Id3 by Blimp-1 limits the formation of memory CD8+ T cells

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12 December 2020

The transcriptional regulators Id2 and Id3 control the formation of distinct memory CD8+ T cell subsets

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12 December 2020

Animal models in autoimmune diseases: lessons learned from mouse models for Sjögren's syndrome

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12 December 2020

E protein transcription factors are required for the development of CD4(+) lineage T cells.

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12 December 2020

E2A and CBP/p300 act in synergy to promote chromatin accessibility of the immunoglobulin κ locus

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12 December 2020

Transcriptional regulator Id2 is required for the CD4 T cell immune response in the development of experimental autoimmune encephalomyelitis.

1 reference

12 December 2020

Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics

1 reference

12 December 2020

Global changes in the nuclear positioning of genes and intra- and interdomain genomic interactions that orchestrate B cell fate

1 reference

12 December 2020

Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing

1 reference

12 December 2020

The genetic landscape of mutations in Burkitt lymphoma

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12 December 2020

Increased level of E protein activity during invariant NKT development promotes differentiation of invariant NKT2 and invariant NKT17 subsets

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12 December 2020

Combined deletion of Id2 and Id3 genes reveals multiple roles for E proteins in invariant NKT cell development and expansion

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12 December 2020

Tracking proliferative history in lymphocyte development with cre-mediated sister chromatid recombination

1 reference

12 December 2020

A recurrent dominant negative E47 mutation causes agammaglobulinemia and BCR(-) B cells.

1 reference

12 December 2020

Peripheral subnuclear positioning suppresses Tcrb recombination and segregates Tcrb alleles from RAG2.

1 reference

12 December 2020

Essential functions for ID proteins at multiple checkpoints in invariant NKT cell development.

1 reference

12 December 2020

Id3 and Id2 act as a dual safety mechanism in regulating the development and population size of innate-like γδ T cells

1 reference

12 December 2020

A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

1 reference

12 December 2020

Labial salivary gland immunopathology in Sjögren's syndrome

1 reference

12 December 2020

B lineage--specific interactions of an immunoglobulin enhancer with cellular factors in vivo

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12 December 2020

Minor salivary gland involvement in Sjögren's syndrome

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12 December 2020

The histopathology of Sjögren's syndrome in labial salivary gland biopsies

1 reference

12 December 2020

Cellular mechanisms of immunologic tolerance

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12 December 2020

Sjögren's syndrome: association of anti-Ro(SS-A) antibodies with vasculitis, hematologic abnormalities, and serologic hyperreactivity

1 reference

12 December 2020

Ro(SSA) and La(SSB) antibodies in the clinical spectrum of Sjögren's syndrome

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12 December 2020

Failure of B-cell differentiation in mice lacking the transcription factor EBF.

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12 December 2020

CD19 of B cells as a surrogate kinase insert region to bind phosphatidylinositol 3-kinase

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12 December 2020

Transformation properties of the E2a-Pbx1 chimeric oncoprotein: fusion with E2a is essential, but the Pbx1 homeodomain is dispensable

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12 December 2020

The helix-loop-helix gene E2A is required for B cell formation

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12 December 2020

E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements

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12 December 2020

Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP

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12 December 2020

Selective events in T cell development

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12 December 2020

Early B-cell development in the mouse: insights from mutations introduced by gene targeting

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12 December 2020

Interleukin 13, a T-cell-derived cytokine that regulates human monocyte and B-cell function

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12 December 2020

T cell receptor antagonist peptides induce positive selection

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12 December 2020

Preferred sequences for DNA recognition by the TAL1 helix-loop-helix proteins

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12 December 2020

Positive selection of lymphocytes

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12 December 2020

A heterodimer of HEB and an E12-related protein interacts with the CD4 enhancer and regulates its activity in T-cell lines

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12 December 2020

The E2A gene product contains two separable and functionally distinct transcription activation domains

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12 December 2020

MHC class II-positive epithelium and mesenchyme cells are both required for T-cell development in the thymus

1 reference

12 December 2020

B-lymphocyte development is regulated by the combined dosage of three basic helix-loop-helix genes, E2A, E2-2, and HEB.

1 reference

12 December 2020

Structural determinants within Pbx1 that mediate cooperative DNA binding with pentapeptide-containing Hox proteins: proposal for a model of a Pbx1-Hox-DNA complex

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12 December 2020

Interaction and functional collaboration of p300/CBP and bHLH proteins in muscle and B-cell differentiation

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12 December 2020

E47 activates the Ig-heavy chain and TdT loci in non-B cells.

1 reference

12 December 2020

Involvement of the E2A basic helix-loop-helix protein in immunoglobulin heavy chain class switching

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12 December 2020

A role for the Wnt gene family in hematopoiesis: expansion of multilineage progenitor cells

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12 December 2020

Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant rag-1-/- mice

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12 December 2020

E2A deficiency leads to abnormalities in alphabeta T-cell development and to rapid development of T-cell lymphomas

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12 December 2020

Regulation of Id3 cell cycle function by Cdk-2-dependent phosphorylation

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12 December 2020

High incidence of T-cell tumors in E2A-null mice and E2A/Id1 double-knockout mice

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12 December 2020

Meis1 and pKnox1 bind DNA cooperatively with Pbx1 utilizing an interaction surface disrupted in oncoprotein E2a-Pbx1

1 reference

12 December 2020

The role of IL-13 and its receptor in allergy and inflammatory responses.

1 reference

12 December 2020

Role of members of the Wnt gene family in human hematopoiesis

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12 December 2020

Requirement for IL-13 independently of IL-4 in experimental asthma

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12 December 2020

Growth inhibition and apoptosis due to restoration of E2A activity in T cell acute lymphoblastic leukemia cells

1 reference

12 December 2020

Ectopic expression of E47 or E12 promotes the death of E2A-deficient lymphomas

1 reference

12 December 2020

10.1016/B978-0-12-405943-6.00004-X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6504980&resulttype=core&format=json

14 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6504980&resulttype=core&format=json

14 May 2020

25248476

1 reference