(Q38255067)

1 September 2017

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title

How do glycolytic enzymes favour cancer cell proliferation by nonmetabolic functions? (English)

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1 September 2017

H Lincet

1

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1 September 2017

P Icard

series ordinal

2

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1 September 2017

language of work or name

English

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publication date

29 September 2014

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1 September 2017

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1 September 2017

volume

34

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1 September 2017

issue

29

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1 September 2017

page(s)

3751-3759

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P/O ratios of mitochondrial oxidative phosphorylation

1 September 2017

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miR-143 regulates hexokinase 2 expression in cancer cells

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A novel miR-155/miR-143 cascade controls glycolysis by regulating hexokinase 2 in breast cancer cells

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MicroRNA-155 functions as an OncomiR in breast cancer by targeting the suppressor of cytokine signaling 1 gene

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The diagnostic validity of the serum tumor marker phosphohexose isomerase (PHI) in patients with gastrointestinal, kidney, and breast cancer

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Autocrine motility factor and its receptor: role in cell locomotion and metastasis

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Regulation of phosphoglucose isomerase/autocrine motility factor expression by hypoxia

31 March 2020

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Phosphoglucose isomerase/autocrine motility factor promotes melanoma cell migration through ERK activation dependent on autocrine production of interleukin-8

31 March 2020

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Autocrine motility factor signaling induces tumor apoptotic resistance by regulations Apaf‐1 and Caspase‐9 apoptosome expression

31 March 2020

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Autocrine motility factor promotes HER2 cleavage and signaling in breast cancer cells

31 March 2020

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PI3K and cancer: lessons, challenges and opportunities

31 March 2020

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Silencing of Autocrine Motility Factor Induces Mesenchymal-to-Epithelial Transition and Suppression of Osteosarcoma Pulmonary Metastasis

31 March 2020

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Epithelial-mesenchymal transitions in development and disease

31 March 2020

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ZNF217 is a marker of poor prognosis in breast cancer that drives epithelial-mesenchymal transition and invasion

31 March 2020

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Phosphoglucose isomerase/autocrine motility factor mediates epithelial-mesenchymal transition regulated by miR-200 in breast cancer cells

31 March 2020

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Reversible high affinity inhibition of phosphofructokinase-1 by acyl-CoA: a mechanism integrating glycolytic flux with lipid metabolism

31 March 2020

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Lactate favours the dissociation of skeletal muscle 6-phosphofructo-1-kinase tetramers down-regulating the enzyme and muscle glycolysis

31 March 2020

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Balancing glycolytic flux: the role of 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatases in cancer metabolism

31 March 2020

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31 March 2020

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31 March 2020

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6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: head-to-head with a bifunctional enzyme that controls glycolysis

31 March 2020

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6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase and tumor cell glycolysis

31 March 2020

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Nuclear targeting of 6-phosphofructo-2-kinase (PFKFB3) increases proliferation via cyclin-dependent kinases

31 March 2020

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E3 ubiquitin ligase APC/C-Cdh1 accounts for the Warburg effect by linking glycolysis to cell proliferation

31 March 2020

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Alteration of aldolase isozymes in serum and tissues of patients with cancer and other diseases

31 March 2020

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Fructose-bisphosphate aldolase a is a potential metastasis-associated marker of lung squamous cell carcinoma and promotes lung cell tumorigenesis and migration

31 March 2020

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Identification of proteomic differences between squamous cell carcinoma of the lung and bronchial epithelium

31 March 2020

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A quantitative proteomic approach for identification of potential biomarkers in hepatocellular carcinoma

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.320

Phospholipase D2 directly interacts with aldolase via Its PH domain

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.320

Aldolase mediates the association of F-actin with the insulin-responsive glucose transporter GLUT4.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.320

Characterization of an aldolase-binding site in the Wiskott-Aldrich syndrome protein

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.320

Targeting of several glycolytic enzymes using RNA interference reveals aldolase affects cancer cell proliferation through a non-glycolytic mechanism

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.320

Amplification of nuclear aldolase A in mouse cell mutants resistant to Hoechst 33342.

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.320

Identification of casein kinase I substrates by in vitro expression cloning screening

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.320

Regulation of mTORC1 and its impact on gene expression at a glance

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.320

Nuclear localization of aldolase A correlates with cell proliferation.

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.320

Aldolase-DNA interactions in a SEWA cell system

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.320

Aldolases a and C are ribonucleolytic components of a neuronal complex that regulates the stability of the light-neurofilament mRNA.

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.320

Involvement of aldolase A in X-ray resistance of human HeLa and UV(r)-1 cells

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.320

Triosephosphate isomerase: a highly evolved biocatalyst

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.320

Proteome analysis of human lung squamous carcinoma

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.320

Proteomic changes in renal cancer and co-ordinate demonstration of both the glycolytic and mitochondrial aspects of the Warburg effect

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.320

Glycoproteomics of paclitaxel resistance in human epithelial ovarian cancer cell lines: towards the identification of putative biomarkers

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.320

Inhibition of triosephosphate isomerase by phosphoenolpyruvate in the feedback-regulation of glycolysis

31 March 2020

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NAD+/NADH and NADP+/NADPH in cellular functions and cell death: regulation and biological consequences

31 March 2020

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The pentose phosphate pathway is a metabolic redox sensor and regulates transcription during the antioxidant response.

31 March 2020

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Pyruvate kinase triggers a metabolic feedback loop that controls redox metabolism in respiring cells

31 March 2020

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Functional inactivation of triosephosphate isomerase through phosphorylation during etoposide-induced apoptosis in HeLa cells: potential role of Cdk2.

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.320

Identification of triosephosphate isomerase as an anti-drug resistance agent in human gastric cancer cells using functional proteomic analysis

31 March 2020

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Novel insight into the role of GAPDH playing in tumor

31 March 2020

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Direct binding of glyceraldehyde 3-phosphate dehydrogenase to telomeric DNA protects telomeres against chemotherapy-induced rapid degradation

31 March 2020

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Novel roles for GAPDH in cell death and carcinogenesis.

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.320

S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 binding

31 March 2020

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Involvement of glyceraldehyde-3-phosphate dehydrogenase in rotenone-induced cell apoptosis: relevance to protein misfolding and aggregation.

31 March 2020

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GAPDH, a novel regulator of the pro-apoptotic mitochondrial membrane permeabilization

31 March 2020

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Proliferative dependent regulation of the glyceraldehyde-3-phosphate dehydrogenase/uracil DNA glycosylase gene in human cells

31 March 2020

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Posttranscriptional control of T cell effector function by aerobic glycolysis

31 March 2020

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The diverse functions of GAPDH: views from different subcellular compartments

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.320

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) induces cancer cell senescence by interacting with telomerase RNA component

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.320

Deregulation of glycolysis in cancer: glyceraldehyde-3-phosphate dehydrogenase as a therapeutic target

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.320

Subcellular dynamics of multifunctional protein regulation: mechanisms of GAPDH intracellular translocation

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.320

Acetylation control of metabolic enzymes in cancer: an updated version.

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.320

SIRT1 interacts with and protects glyceraldehyde-3-phosphate dehydrogenase (GAPDH) from nuclear translocation: implications for cell survival after irradiation.

31 March 2020

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Glyceraldehyde-3-phosphate dehydrogenase is activated by lysine 254 acetylation in response to glucose signal.

31 March 2020

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Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosis

31 March 2020

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Nuclear translocation of glyceraldehyde-3-phosphate dehydrogenase is regulated by acetylation

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.320

Akt2 kinase suppresses glyceraldehyde-3-phosphate dehydrogenase (GAPDH)-mediated apoptosis in ovarian cancer cells via phosphorylating GAPDH at threonine 237 and decreasing its nuclear translocation

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.320

Glyceraldehyde 3-phosphate dehydrogenase is a SET-binding protein and regulates cyclin B-cdk1 activity

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.320

Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.320

GAPDH and autophagy preserve survival after apoptotic cytochrome c release in the absence of caspase activation.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.320

Quantitative proteomics identification of phosphoglycerate mutase 1 as a novel therapeutic target in hepatocellular carcinoma

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.320

Comparative proteomic profiling of human bile reveals SSP411 as a novel biomarker of cholangiocarcinoma

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.320

Target discovery in small-molecule cell-based screens by in situ proteome reactivity profiling

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.320

Hypoxia-induced expression of phosphoglycerate mutase B in fibroblasts

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.320

Comparative proteome analysis reveals differential regulation of glycolytic and antioxidant enzymes in cortex and hippocampus exposed to short-term hypobaric hypoxia.

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.320

Mechanistic and structural requirements for active site labeling of phosphoglycerate mutase by spiroepoxides

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.320

Phosphoglycerate Mutase 1 Coordinates Glycolysis and Biosynthesis to Promote Tumor Growth

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.320

Regulation of cellular metabolism by protein lysine acetylation

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.320

Regulation of glycolytic enzyme phosphoglycerate mutase-1 by Sirt1 protein-mediated deacetylation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.320

Tyr26 phosphorylation of PGAM1 provides a metabolic advantage to tumours by stabilizing the active conformation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.320

Influence of salt, substrate, and cofactor concentrations on the kinetic and mechanistic behavior of phosphoglycerate mutase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.320

Evidence for an alternative glycolytic pathway in rapidly proliferating cells

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.320

Pyruvate kinase type M2: a key regulator of the metabolic budget system in tumor cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.320

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.320

HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.320

Turning on a fuel switch of cancer: hnRNP proteins regulate alternative splicing of pyruvate kinase mRNA.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.320

Oleanolic acid suppresses aerobic glycolysis in cancer cells by switching pyruvate kinase type M isoforms

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.320

PKM2 contributes to cancer metabolism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.320

PKM2 and ACVR 1C are prognostic markers for poor prognosis of gallbladder cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.320

Pyruvate kinase M2 expression, but not pyruvate kinase activity, is up-regulated in a grade-specific manner in human glioma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.320

Nuclear PKM2 expression predicts poor prognosis in patients with esophageal squamous cell carcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.320

Emerging roles of PKM2 in cell metabolism and cancer progression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.320

Multiple biological activities of lactic acid in cancer: influences on tumor growth, angiogenesis and metastasis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.320

Serine is a natural ligand and allosteric activator of pyruvate kinase M2

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.320

PKM2 isoform-specific deletion reveals a differential requirement for pyruvate kinase in tumor cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.320

Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.320

Pyruvate kinase M2 is a phosphotyrosine-binding protein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.320

Pyruvate kinase M2 and cancer: an updated assessment

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.320

Pyruvate kinase M2 regulates gene transcription by acting as a protein kinase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.320

Acetylation targets the M2 isoform of pyruvate kinase for degradation through chaperone-mediated autophagy and promotes tumor growth.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.320

Mitogenic and oncogenic stimulation of K433 acetylation promotes PKM2 protein kinase activity and nuclear localization

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.320

Regulation and function of pyruvate kinase M2 in cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.320

c-Myc and cancer metabolism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.320

Mucins in cancer: function, prognosis and therapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.320

MUC1: a multifaceted oncoprotein with a key role in cancer progression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.320

MUC1-C oncoprotein regulates glycolysis and pyruvate kinase M2 activity in cancer cells

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.320

Nuclear translocation of the tumor marker pyruvate kinase M2 induces programmed cell death

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.320

Regulation of cell proliferation by interleukin-3-induced nuclear translocation of pyruvate kinase.

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.320

ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.320

JMJD5 regulates PKM2 nuclear translocation and reprograms HIF-1α-mediated glucose metabolism.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.320

Pyruvate kinase isozyme type M2 (PKM2) interacts and cooperates with Oct-4 in regulating transcription

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.320

Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.320

A STAT3-mediated metabolic switch is involved in tumour transformation and STAT3 addiction.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.320

Pyruvate kinase M2 facilitates colon cancer cell migration via the modulation of STAT3 signalling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.320

Pyruvate kinase M2 plays a dual role on regulation of the EGF/EGFR signaling via E-cadherin-dependent manner in gastric cancer cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.320

PKM2 phosphorylates histone H3 and promotes gene transcription and tumorigenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.320

The L- and R-type isozymes of rat pyruvate kinase are produced from a single gene by use of different promoters

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Down-regulation of phosphoglucose isomerase/autocrine motility factor enhances gensenoside Rh2 pharmacological action on leukemia KG1α cells

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New facets of matrix metalloproteinases MMP-2 and MMP-9 as cell surface transducers: outside-in signaling and relationship to tumor progression

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Expression and secretion of neuroleukin/phosphohexose isomerase/maturation factor as autocrine motility factor by tumor cells.

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12 December 2020

A global view of the biochemical pathways involved in the regulation of the metabolism of cancer cells

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12 December 2020

The M1- and M2-type isozymes of rat pyruvate kinase are produced from the same gene by alternative RNA splicing

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12 December 2020

Subcellular localization of aldolase B

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12 December 2020

Differential expression of MUC1, MUC2, and MUC5AC in carcinomas of various sites: an immunohistochemical study

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Overexpression of the autocrine motility factor/phosphoglucose isomerase induces transformation and survival of NIH-3T3 fibroblasts

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12 December 2020

Glycolysis module activated by hypoxia-inducible factor 1alpha is related to the aggressive phenotype of hepatocellular carcinoma.

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12 December 2020

Tissue-specific expression of rat aldolase A mRNAs. Three molecular species differing only in the 5'-terminal sequences.

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12 December 2020

Tissue-specific isoform switch and DNA hypomethylation of the pyruvate kinase PKM gene in human cancers.

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12 December 2020

A nuclear protein complex containing high mobility group proteins B1 and B2, heat shock cognate protein 70, ERp60, and glyceraldehyde-3-phosphate dehydrogenase is involved in the cytotoxic response to DNA modified by incorporation of anticancer nucl

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12 December 2020

High expression of inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (iPFK-2; PFKFB3) in human cancers

1 reference

12 December 2020

Tumor cell autocrine motility factor is the neuroleukin/phosphohexose isomerase polypeptide

1 reference

12 December 2020

MUC1: a novel metabolic master regulator

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12 December 2020

Dysregulation of glucose transport, glycolysis, TCA cycle and glutaminolysis by oncogenes and tumor suppressors in cancer cells

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Proteomic analysis of lung adenocarcinoma: identification of a highly expressed set of proteins in tumors.

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12 December 2020

PKM2, STAT3 and HIF-1α: The Warburg's vicious circle

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Identifiers

DOI

10.1038/ONC.2014.320

1 reference

Dimensions Publication ID

1 September 2017

1013378291

0 references

1 reference