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Signalling dynamics in the spindle checkpoint response
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scholarly article
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Europe PubMed Central
PMCID
4283840
retrieved
1 September 2017
review article
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stated in
Europe PubMed Central
title
Signalling dynamics in the spindle checkpoint response
(English)
1 reference
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Europe PubMed Central
PMCID
4283840
retrieved
1 September 2017
author
Sue Biggins
object named as
Sue Biggins
series ordinal
2
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author name string
Nitobe London
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
4283840
retrieved
1 September 2017
publication date
10 October 2014
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stated in
Europe PubMed Central
PMCID
4283840
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1 September 2017
published in
Nature Reviews Molecular Cell Biology
1 reference
stated in
Europe PubMed Central
PMCID
4283840
retrieved
1 September 2017
volume
15
1 reference
stated in
Europe PubMed Central
PMCID
4283840
retrieved
1 September 2017
issue
11
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stated in
Europe PubMed Central
PMCID
4283840
retrieved
1 September 2017
page(s)
736-747
1 reference
stated in
Europe PubMed Central
PMCID
4283840
retrieved
1 September 2017
exact match
https://scigraph.springernature.com/pub.10.1038/nrm3888
0 references
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Inefficient degradation of cyclin B1 re-activates the spindle checkpoint right after sister chromatid disjunction
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6 September 2017
The dynamic protein Knl1 - a kinetochore rendezvous
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6 September 2017
CENP-I and Aurora B act as a molecular switch that ties RZZ/Mad1 recruitment to kinetochore attachment status.
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6 September 2017
Chk2 prevents mitotic exit when the majority of kinetochores are unattached
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6 September 2017
The current view for the silencing of the spindle assembly checkpoint
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6 September 2017
Phosphorylation at threonine 288 by cell cycle checkpoint kinase 2 (CHK2) controls human monopolar spindle 1 (Mps1) kinetochore localization
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6 September 2017
Conditional targeting of MAD1 to kinetochores is sufficient to reactivate the spindle assembly checkpoint in metaphase
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PubMed Central
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6 September 2017
Recruitment of Mad1 to metaphase kinetochores is sufficient to reactivate the mitotic checkpoint.
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6 September 2017
Cdk1 inactivation terminates mitotic checkpoint surveillance and stabilizes kinetochore attachments in anaphase
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6 September 2017
Dependency of the spindle assembly checkpoint on Cdk1 renders the anaphase transition irreversible
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PubMed Central
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6 September 2017
Nuclear pores protect genome integrity by assembling a premitotic and Mad1-dependent anaphase inhibitor
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6 September 2017
A Bub1-Mad1 interaction targets the Mad1-Mad2 complex to unattached kinetochores to initiate the spindle checkpoint
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6 September 2017
Mad1 contribution to spindle assembly checkpoint signalling goes beyond presenting Mad2 at kinetochores
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6 September 2017
A direct role of Mad1 in the spindle assembly checkpoint beyond Mad2 kinetochore recruitment
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6 September 2017
Mad1 kinetochore recruitment by Mps1-mediated phosphorylation of Bub1 signals the spindle checkpoint.
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PubMed Central
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6 September 2017
KI motifs of human Knl1 enhance assembly of comprehensive spindle checkpoint complexes around MELT repeats
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6 September 2017
Arrayed BUB recruitment modules in the kinetochore scaffold KNL1 promote accurate chromosome segregation
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6 September 2017
Spindle assembly checkpoint robustness requires Tpr-mediated regulation of Mad1/Mad2 proteostasis
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6 September 2017
The signaling network that silences the spindle assembly checkpoint upon the establishment of chromosome bipolar attachment
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6 September 2017
KNL1: bringing order to the kinetochore
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6 September 2017
Phosphorylation of microtubule-binding protein Hec1 by mitotic kinase Aurora B specifies spindle checkpoint kinase Mps1 signaling at the kinetochore.
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6 September 2017
Monopolar spindle 1 (MPS1) kinase promotes production of closed MAD2 (C-MAD2) conformer and assembly of the mitotic checkpoint complex
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6 September 2017
Kinetic framework of spindle assembly checkpoint signalling
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6 September 2017
The spindle assembly checkpoint works like a rheostat rather than a toggle switch
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6 September 2017
Dual personality of Mad1: regulation of nuclear import by a spindle assembly checkpoint protein
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6 September 2017
Bub3 reads phosphorylated MELT repeats to promote spindle assembly checkpoint signaling
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6 September 2017
Spindle assembly checkpoint proteins are positioned close to core microtubule attachment sites at kinetochores.
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6 September 2017
Tracking spindle checkpoint signals from kinetochores to APC/C.
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6 September 2017
A TPR domain–containing N-terminal module of MPS1 is required for its kinetochore localization by Aurora B
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6 September 2017
Aneuploidy in health, disease, and aging
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6 September 2017
Making an effective switch at the kinetochore by phosphorylation and dephosphorylation
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6 September 2017
The KMN protein network--chief conductors of the kinetochore orchestra
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6 September 2017
Microtubule attachment and spindle assembly checkpoint signalling at the kinetochore
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6 September 2017
Mitosis-specific regulation of nuclear transport by the spindle assembly checkpoint protein Mad1p
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6 September 2017
The Mad1-Mad2 balancing act--a damaged spindle checkpoint in chromosome instability and cancer
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6 September 2017
Mad2 and the APC/C compete for the same site on Cdc20 to ensure proper chromosome segregation
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6 September 2017
Evolution and function of the mitotic checkpoint
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6 September 2017
Connecting up and clearing out: how kinetochore attachment silences the spindle assembly checkpoint.
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6 September 2017
Mps1 promotes rapid centromere accumulation of Aurora B.
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6 September 2017
Role of phosphorylation of Cdc20 in p31(comet)-stimulated disassembly of the mitotic checkpoint complex
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6 September 2017
Structure of human Mad1 C-terminal domain reveals its involvement in kinetochore targeting
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6 September 2017
The MPS1 family of protein kinases
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6 September 2017
Structure of the mitotic checkpoint complex
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6 September 2017
A conserved role for COMA/CENP-H/I/N kinetochore proteins in the spindle checkpoint.
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6 September 2017
Microtubule binding by KNL-1 contributes to spindle checkpoint silencing at the kinetochore
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6 September 2017
Structural analysis reveals features of the spindle checkpoint kinase Bub1-kinetochore subunit Knl1 interaction
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6 September 2017
Causes and consequences of aneuploidy in cancer.
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6 September 2017
Killing cells by targeting mitosis
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6 September 2017
Mad2 and Mad3 cooperate to arrest budding yeast in mitosis
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6 September 2017
Centromere-tethered Mps1 pombe homolog (Mph1) kinase is a sufficient marker for recruitment of the spindle checkpoint protein Bub1, but not Mad1.
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6 September 2017
Spindle checkpoint silencing: PP1 tips the balance.
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6 September 2017
Structure of a Blinkin-BUBR1 Complex Reveals an Interaction Crucial for Kinetochore-Mitotic Checkpoint Regulation via an Unanticipated Binding Site
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6 September 2017
Phosphorylation of the Ndc80 complex protein, HEC1, by Nek2 kinase modulates chromosome alignment and signaling of the spindle assembly checkpoint.
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6 September 2017
Zwint-1 is a novel Aurora B substrate required for the assembly of a dynein-binding platform on kinetochores.
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6 September 2017
KNL1/Spc105 recruits PP1 to silence the spindle assembly checkpoint
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6 September 2017
Bub1 and BubR1: at the interface between chromosome attachment and the spindle checkpoint
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6 September 2017
BUBR1 and closed MAD2 (C-MAD2) interact directly to assemble a functional mitotic checkpoint complex
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6 September 2017
Spindly switch controls anaphase: spindly and RZZ functions in chromosome attachment and mitotic checkpoint control
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6 September 2017
The 'anaphase problem': how to disable the mitotic checkpoint when sisters split
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6 September 2017
Kinetochore-microtubule interactions: steps towards bi-orientation
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6 September 2017
Kinetochores' gripping feat: conformational wave or biased diffusion?
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6 September 2017
Laterally attached kinetochores recruit the checkpoint protein Bub1, but satisfy the spindle checkpoint
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6 September 2017
How cyclin A destruction escapes the spindle assembly checkpoint
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6 September 2017
Mps1 directs the assembly of Cdc20 inhibitory complexes during interphase and mitosis to control M phase timing and spindle checkpoint signaling.
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6 September 2017
Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine
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6 September 2017
Sustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1-C-Mad2 core complex
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6 September 2017
Removal of Spindly from microtubule-attached kinetochores controls spindle checkpoint silencing in human cells
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6 September 2017
Regulated targeting of protein phosphatase 1 to the outer kinetochore by KNL1 opposes Aurora B kinase
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6 September 2017
Defining the Molecular Basis of BubR1 Kinetochore Interactions and APC/C-CDC20 Inhibition
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6 September 2017
Welcome to a new kind of tension: translating kinetochore mechanics into a wait-anaphase signal
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6 September 2017
Phosphorylation of H2A by Bub1 prevents chromosomal instability through localizing shugoshin
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6 September 2017
Protein phosphatase 1 regulates exit from the spindle checkpoint in budding yeast
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6 September 2017
Bub1 regulates chromosome segregation in a kinetochore-independent manner
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6 September 2017
Intrakinetochore stretch is associated with changes in kinetochore phosphorylation and spindle assembly checkpoint activity
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6 September 2017
The Mad2 partial unfolding model: regulating mitosis through Mad2 conformational switching
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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6 September 2017
Protein metamorphosis: the two-state behavior of Mad2.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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6 September 2017
SPDL-1 functions as a kinetochore receptor for MDF-1 in Caenorhabditis elegans
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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6 September 2017
A new mechanism controlling kinetochore-microtubule interactions revealed by comparison of two dynein-targeting components: SPDL-1 and the Rod/Zwilch/Zw10 complex
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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6 September 2017
The chromosomal passenger complex and the spindle assembly checkpoint: kinetochore-microtubule error correction and beyond
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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6 September 2017
Insights into Mad2 Regulation in the Spindle Checkpoint Revealed by the Crystal Structure of the Symmetric Mad2 Dimer
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PubMed Central
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6 September 2017
Bub1 is a fission yeast kinetochore scaffold protein, and is sufficient to recruit other spindle checkpoint proteins to ectopic sites on chromosomes
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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6 September 2017
Bub1 kinase targets Sgo1 to ensure efficient chromosome biorientation in budding yeast mitosis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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6 September 2017
Mps1 kinase promotes sister-kinetochore bi-orientation by a tension-dependent mechanism
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
retrieved
6 September 2017
Human Blinkin/AF15q14 is required for chromosome alignment and the mitotic checkpoint through direct interaction with Bub1 and BubR1
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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6 September 2017
The spindle-assembly checkpoint in space and time
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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6 September 2017
Mad3p, a pseudosubstrate inhibitor of APCCdc20 in the spindle assembly checkpoint
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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6 September 2017
Structural analysis of Bub3 interactions in the mitotic spindle checkpoint
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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6 September 2017
KEN-box-dependent degradation of the Bub1 spindle checkpoint kinase by the anaphase-promoting complex/cyclosome.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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6 September 2017
The conserved KMN network constitutes the core microtubule-binding site of the kinetochore
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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6 September 2017
The Ipl1-Aurora protein kinase activates the spindle checkpoint by creating unattached kinetochores
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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6 September 2017
On the road to cancer: aneuploidy and the mitotic checkpoint
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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6 September 2017
ZW10 links mitotic checkpoint signaling to the structural kinetochore.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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6 September 2017
The A78V mutation in the Mad3-like domain of Schizosaccharomyces pombe Bub1p perturbs nuclear accumulation and kinetochore targeting of Bub1p, Bub3p, and Mad3p and spindle assembly checkpoint function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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6 September 2017
Stuck in division or passing through: what happens when cells cannot satisfy the spindle assembly checkpoint
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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6 September 2017
Kinetochore targeting of fission yeast Mad and Bub proteins is essential for spindle checkpoint function but not for all chromosome segregation roles of Bub1p
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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6 September 2017
Kinetochore localization of spindle checkpoint proteins: who controls whom?
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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6 September 2017
Timing and checkpoints in the regulation of mitotic progression
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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6 September 2017
Spindle checkpoint protein dynamics at kinetochores in living cells.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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6 September 2017
Dynamics of centromere and kinetochore proteins; implications for checkpoint signaling and silencing
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
retrieved
6 September 2017
Bub1 is required for kinetochore localization of BubR1, Cenp-E, Cenp-F and Mad2, and chromosome congression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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6 September 2017
Spindle checkpoint proteins and chromosome-microtubule attachment in budding yeast
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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6 September 2017
Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome loss
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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6 September 2017
Cyclin B destruction triggers changes in kinetochore behavior essential for successful anaphase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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6 September 2017
BubR1 is essential for kinetochore localization of other spindle checkpoint proteins and its phosphorylation requires Mad1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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6 September 2017
Crystal structure of the tetrameric Mad1-Mad2 core complex: implications of a 'safety belt' binding mechanism for the spindle checkpoint
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
retrieved
6 September 2017
Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
retrieved
6 September 2017
Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
retrieved
6 September 2017
Spindle checkpoint protein Bub1 is required for kinetochore localization of Mad1, Mad2, Bub3, and CENP-E, independently of its kinase activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
retrieved
6 September 2017
Visualization of Mad2 dynamics at kinetochores, along spindle fibers, and at spindle poles in living cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
retrieved
6 September 2017
Complex formation between Mad1p, Bub1p and Bub3p is crucial for spindle checkpoint function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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6 September 2017
Temporal and spatial control of cyclin B1 destruction in metaphase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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6 September 2017
The spindle checkpoint of budding yeast depends on a tight complex between the Mad1 and Mad2 proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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6 September 2017
The hBUB1 and hBUBR1 kinases sequentially assemble onto kinetochores during prophase with hBUBR1 concentrating at the kinetochore plates in mitosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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6 September 2017
Mitosis in vertebrate somatic cells with two spindles: implications for the metaphase/anaphase transition checkpoint and cleavage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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6 September 2017
Tension-sensitive kinetochore phosphorylation and the chromosome distribution checkpoint in praying mantid spermatocytes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
retrieved
6 September 2017
Association of spindle assembly checkpoint component XMAD2 with unattached kinetochores
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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6 September 2017
Activation of the budding yeast spindle assembly checkpoint without mitotic spindle disruption.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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6 September 2017
Mitotic forces control a cell-cycle checkpoint
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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6 September 2017
Differential expression of a phosphoepitope at the kinetochores of moving chromosomes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
retrieved
6 September 2017
The checkpoint delaying anaphase in response to chromosome monoorientation is mediated by an inhibitory signal produced by unattached kinetochores
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
retrieved
6 September 2017
Kinetochore chemistry is sensitive to tension and may link mitotic forces to a cell cycle checkpoint
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
retrieved
6 September 2017
Feedback control of mitosis in budding yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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6 September 2017
S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
retrieved
6 September 2017
Aurora B potentiates Mps1 activation to ensure rapid checkpoint establishment at the onset of mitosis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
retrieved
6 September 2017
Fission yeast Mad3p is required for Mad2p to inhibit the anaphase-promoting complex and localizes to kinetochores in a Bub1p-, Bub3p-, and Mph1p-dependent manner
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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14 September 2017
Motors or dynamics: what really moves chromosomes?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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14 September 2017
Tension-sensitive kinetochore phosphorylation in vitro.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
retrieved
28 September 2017
Cohesin cleavage and Cdk inhibition trigger formation of daughter nuclei
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
retrieved
28 September 2017
Phosphoregulation of Spc105 by Mps1 and PP1 regulates Bub1 localization to kinetochores
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
retrieved
23 June 2018
Kinase activity of fission yeast Mph1 is required for Mad2 and Mad3 to stably bind the anaphase promoting complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
retrieved
23 June 2018
Spindle checkpoint silencing requires association of PP1 to both Spc7 and kinesin-8 motors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
retrieved
23 June 2018
Constitutive Mad1 targeting to kinetochores uncouples checkpoint signalling from chromosome biorientation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
retrieved
23 June 2018
Protein interaction domain mapping of human kinetochore protein Blinkin reveals a consensus motif for binding of spindle assembly checkpoint proteins Bub1 and BubR1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
retrieved
23 June 2018
Release of Mps1 from kinetochores is crucial for timely anaphase onset.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
retrieved
23 June 2018
BubR1 N terminus acts as a soluble inhibitor of cyclin B degradation by APC/C(Cdc20) in interphase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
retrieved
23 June 2018
Slow checkpoint activation kinetics as a safety device in anaphase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
retrieved
31 August 2018
A minimal number of MELT repeats supports all the functions of KNL1 in chromosome segregation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
retrieved
31 August 2018
Determinants of robustness in spindle assembly checkpoint signalling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
retrieved
31 August 2018
Catalytic assembly of the mitotic checkpoint inhibitor BubR1-Cdc20 by a Mad2-induced functional switch in Cdc20.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
retrieved
31 August 2018
Mph1 kinetochore localization is crucial and upstream in the hierarchy of spindle assembly checkpoint protein recruitment to kinetochores.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
retrieved
31 August 2018
The vertebrate mitotic checkpoint protein BUBR1 is an unusual pseudokinase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
retrieved
31 August 2018
MPS1/Mph1 phosphorylates the kinetochore protein KNL1/Spc7 to recruit SAC components
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
retrieved
31 August 2018
Phosphodependent recruitment of Bub1 and Bub3 to Spc7/KNL1 by Mph1 kinase maintains the spindle checkpoint.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
retrieved
31 August 2018
Sli15(INCENP) dephosphorylation prevents mitotic checkpoint reengagement due to loss of tension at anaphase onset
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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31 August 2018
A novel protein phosphatase 1-dependent spindle checkpoint silencing mechanism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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31 August 2018
In vitro FRAP identifies the minimal requirements for Mad2 kinetochore dynamics.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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31 August 2018
The Rae1-Nup98 complex prevents aneuploidy by inhibiting securin degradation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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31 August 2018
Analysis of Bub3 spindle checkpoint function in Xenopus egg extracts.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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31 August 2018
A MAP kinase-dependent spindle assembly checkpoint in Xenopus egg extracts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4283840
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31 August 2018
Anaphase inactivation of the spindle checkpoint
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stated in
Crossref
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https://api.crossref.org/works/10.1038%2FNRM3888
retrieved
31 March 2020
Identifiers
DOI
10.1038/NRM3888
1 reference
stated in
Europe PubMed Central
PMCID
4283840
retrieved
1 September 2017
Dimensions Publication ID
1005415561
0 references
PMCID
4283840
1 reference
stated in
Europe PubMed Central
PMCID
4283840
retrieved
1 September 2017
PubMed ID
25303117
1 reference
stated in
Europe PubMed Central
PMCID
4283840
retrieved
1 September 2017
ResearchGate publication ID
266746177
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