(Q38266428)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25382779%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

review article

1 reference

title

Lysine methylation in cancer: SMYD3-MAP3K2 teaches us new lessons in the Ras-ERK pathway (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25382779%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25382779%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

author name string

Paula Colón-Bolea

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25382779%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

language of work or name

English

0 references

publication date

2 September 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25382779%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25382779%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

volume

36

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25382779%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25382779%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

page(s)

1162-1169

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25382779%20AND%20SRC:MED&resulttype=core&format=json

Histone lysine methylation dynamics: establishment, regulation, and biological impact

22 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201400120

The functional diversity of protein lysine methylation

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Lysine methylation: beyond histones

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Methylation of H3-lysine 79 is mediated by a new family of HMTases without a SET domain

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The SET-domain protein superfamily: protein lysine methyltransferases

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Regulation of p53 activity through lysine methylation

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Histone lysine methyltransferase SETD8 promotes carcinogenesis by deregulating PCNA expression

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Reversible methylation of promoter-bound STAT3 by histone-modifying enzymes

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Modulation of retinoic acid receptor alpha activity by lysine methylation in the DNA binding domain

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Lysine methylation regulates E2F1-induced cell death

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Regulation of Estrogen Receptor α by the SET7 Lysine Methyltransferase

21 January 2018

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Regulation of NF-kappaB by NSD1/FBXL11-dependent reversible lysine methylation of p65.

21 January 2018

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PRC2 directly methylates GATA4 and represses its transcriptional activity

21 January 2018

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Lysine methylation of FOXO3 regulates oxidative stress-induced neuronal cell death

21 January 2018

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G9a-mediated lysine methylation alters the function of CCAAT/enhancer-binding protein-beta.

21 January 2018

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Methylation of the retinoblastoma tumor suppressor by SMYD2

21 January 2018

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Protein lysine methyltransferase G9a acts on non-histone targets

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Regulation of DNMT1 stability through SET7-mediated lysine methylation in mammalian cells

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Methylation of proteins involved in translation

21 January 2018

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Cytoplasmic protein methylation is essential for neural crest migration.

21 January 2018

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The HSP90 family of genes in the human genome: insights into their divergence and evolution

21 January 2018

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Smyd2 controls cytoplasmic lysine methylation of Hsp90 and myofilament organization

21 January 2018

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SMYD2-dependent HSP90 methylation promotes cancer cell proliferation by regulating the chaperone complex formation

21 January 2018

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Identification and characterization of a novel human methyltransferase modulating Hsp70 protein function through lysine methylation

21 January 2018

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Enhanced HSP70 lysine methylation promotes proliferation of cancer cells through activation of Aurora kinase B.

21 January 2018

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The lysine 831 of vascular endothelial growth factor receptor 1 is a novel target of methylation by SMYD3.

21 January 2018

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Lysine methylation promotes VEGFR-2 activation and angiogenesis

21 January 2018

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Proteomics study reveals cross-talk between Rho guanidine nucleotide dissociation inhibitor 1 post-translational modifications in epidermal growth factor stimulated fibroblasts

21 January 2018

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A proteomic approach for the identification of novel lysine methyltransferase substrates

21 January 2018

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Post-translational modifications in the rat lumbar spinal cord in experimental autoimmune encephalomyelitis

21 January 2018

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A method for the comprehensive proteomic analysis of membrane proteins

21 January 2018

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Tipping the lysine methylation balance in disease

21 January 2018

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Enhanced SMYD3 expression is essential for the growth of breast cancer cells

21 January 2018

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Overexpression of SMYD2 relates to tumor cell proliferation and malignant outcome of esophageal squamous cell carcinoma

21 January 2018

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Alterations of DNA methylation and histone modifications contribute to gene silencing in hepatocellular carcinomas.

21 January 2018

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H3K9 histone methyltransferase G9a promotes lung cancer invasion and metastasis by silencing the cell adhesion molecule Ep-CAM.

21 January 2018

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G9a and Glp methylate lysine 373 in the tumor suppressor p53

21 January 2018

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Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27)

21 January 2018

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The polycomb group protein EZH2 is involved in progression of prostate cancer

21 January 2018

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EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

21 January 2018

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Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders

21 January 2018

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NSD2 links dimethylation of histone H3 at lysine 36 to oncogenic programming

21 January 2018

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LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer

21 January 2018

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The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescence

21 January 2018

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Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer

21 January 2018

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Histone methyltransferase gene SETD2 is a novel tumor suppressor gene in clear cell renal cell carcinoma.

21 January 2018

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Genomic amplification and oncogenic properties of the GASC1 histone demethylase gene in breast cancer

21 January 2018

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Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma

21 January 2018

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Context-specific regulation of cancer epigenomes by histone and transcription factor methylation

21 January 2018

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Histone methyltransferases in cancer

21 January 2018

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Regulation of p53 function by lysine methylation

21 January 2018

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Methylation-acetylation interplay activates p53 in response to DNA damage

21 January 2018

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Repression of p53 activity by Smyd2-mediated methylation

21 January 2018

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Modulation of p53 function by SET8-mediated methylation at lysine 382

21 January 2018

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The MBT Repeats of L3MBTL1 Link SET8-mediated p53 Methylation at Lysine 382 to Target Gene Repression

21 January 2018

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Lysine methylation regulates the pRb tumour suppressor protein

21 January 2018

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RB1 methylation by SMYD2 enhances cell cycle progression through an increase of RB1 phosphorylation

21 January 2018

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Negative regulation of hypoxic responses via induced Reptin methylation.

21 January 2018

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NUP98-NSD1 links H3K36 methylation to Hox-A gene activation and leukaemogenesis.

21 January 2018

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SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells

21 January 2018

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SMYD3 promotes cancer invasion by epigenetic upregulation of the metalloproteinase MMP-9.

21 January 2018

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Smyd3 regulates cancer cell phenotypes and catalyzes histone H4 lysine 5 methylation.

21 January 2018

1 reference

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SMYD3 as an oncogenic driver in prostate cancer by stimulation of androgen receptor transcription

21 January 2018

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Knockdown of SMYD3 by RNA interference down-regulates c-Met expression and inhibits cells migration and invasion induced by HGF.

21 January 2018

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The telomerase reverse transcriptase (hTERT) gene is a direct target of the histone methyltransferase SMYD3.

21 January 2018

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The Ras-ERK pathway: understanding site-specific signaling provides hope of new anti-tumor therapies.

21 January 2018

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Mutated KRAS results in overexpression of DUSP4, a MAP-kinase phosphatase, and SMYD3, a histone methyltransferase, in rectal carcinomas

21 January 2018

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SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIES.201400120

Wiring diagrams of MAPK regulation by MEKK1, 2, and 3.

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIES.201400120

Role of mitogen-activated protein kinase kinase kinases in signal integration

21 January 2018

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A direct HDAC4-MAP kinase crosstalk activates muscle atrophy program

21 January 2018

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https://api.crossref.org/works/10.1002%2FBIES.201400120

CHIP-dependent termination of MEKK2 regulates temporal ERK activation required for proper hyperosmotic response

21 January 2018

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MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42

21 January 2018

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Differential modification of Ras proteins by ubiquitination

21 January 2018

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Oncogenic Ras abrogates MEK SUMOylation that suppresses the ERK pathway and cell transformation

21 January 2018

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Regulation of RAS oncogenicity by acetylation

21 January 2018

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Regulation of the mitogen-activated protein kinase kinase (MEK)-1 by NAD(+)-dependent deacetylases

21 January 2018

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The serine/threonine phosphatase, PP2A: endogenous regulator of inflammatory cell signaling.

21 January 2018

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Cytokine activation of p38 mitogen-activated protein kinase and apoptosis is opposed by alpha-4 targeting of protein phosphatase 2A for site-specific dephosphorylation of MEK3.

21 January 2018

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Chromatin proteins and modifications as drug targets

21 January 2018

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Specificity Analysis-Based Identification of New Methylation Targets of the SET7/9 Protein Lysine Methyltransferase

21 January 2018

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Overexpression of G9a and MCM7 in oesophageal squamous cell carcinoma is associated with poor prognosis

21 January 2018

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