(Q38268791)

1 September 2017

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title

Postdependent state in rats as a model for medication development in alcoholism (English)

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1 September 2017

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2

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1 September 2017

Marcus W Meinhardt

1

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1 September 2017

publication date

17 November 2014

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1 September 2017

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1 September 2017

volume

20

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1 September 2017

issue

1

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1 September 2017

page(s)

1-21

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Effectiveness and safety of baclofen for maintenance of alcohol abstinence in alcohol-dependent patients with liver cirrhosis: randomised, double-blind controlled study

1 September 2017

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21 January 2018

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Metabotropic glutamate receptor 5 activity in the nucleus accumbens is required for the maintenance of ethanol self-administration in a rat genetic model of high alcohol intake

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21 January 2018

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Genetic variation and brain gene expression in rodent models of alcoholism implications for medication development

21 January 2018

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The mGluR2/3 agonist LY379268 induced anti-reinstatement effects in rats exhibiting addiction-like behavior.

21 January 2018

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Single-nucleotide polymorphisms in corticotropin releasing hormone receptor 1 gene (CRHR1) are associated with quantitative trait of event-related potential and alcohol dependence

21 January 2018

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Awake rat pharmacological magnetic resonance imaging as a translational pharmacodynamic biomarker: metabotropic glutamate 2/3 agonist modulation of ketamine-induced blood oxygenation level dependence signals.

21 January 2018

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Reinstatement of ethanol-seeking behavior by drug cues following single versus multiple ethanol intoxication in the rat: effects of naltrexone

21 January 2018

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Buprenorphine reduces alcohol drinking through activation of the nociceptin/orphanin FQ-NOP receptor system

21 January 2018

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Cannabinoid CB1 receptor antagonism reduces conditioned reinstatement of ethanol-seeking behavior in rats

21 January 2018

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Alcohol-induced neurodegeneration, suppression of transforming growth factor-beta, and cognitive impairment in rats: prevention by group II metabotropic glutamate receptor activation

21 January 2018

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The novel, selective, brain-penetrant neuropeptide Y Y2 receptor antagonist, JNJ-31020028, tested in animal models of alcohol consumption, relapse, and anxiety.

21 January 2018

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Role of GABAB receptor in alcohol dependence: Reducing effect of baclofen on alcohol intake and alcohol motivational properties in rats and amelioration of alcohol withdrawal syndrome and alcohol craving in human alcoholics

21 January 2018

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21 January 2018

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Dysregulation of nociceptin/orphanin FQ activity in the amygdala is linked to excessive alcohol drinking in the rat.

21 January 2018

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Evidence that vasopressin V1b receptors mediate the transition to excessive drinking in ethanol-dependent rats

21 January 2018

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Can experimental paradigms and animal models be used to discover clinically effective medications for alcoholism?

21 January 2018

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Neural systems of reinforcement for drug addiction: from actions to habits to compulsion

21 January 2018

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Effects of prior ethanol exposure on ethanol self-administration in a continuous access situation using retractable drinking tubes.

21 January 2018

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Corticotropin-releasing factor within the central nucleus of the amygdala mediates enhanced ethanol self-administration in withdrawn, ethanol-dependent rats.

21 January 2018

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Corticotropin-releasing factor 1 antagonists selectively reduce ethanol self-administration in ethanol-dependent rats

21 January 2018

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Efficacy and safety of baclofen for alcohol dependence: a randomized, double-blind, placebo-controlled trial

21 January 2018

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Glutamatergic substrates of drug addiction and alcoholism

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3-(4-Chloro-2-morpholin-4-yl-thiazol-5-yl)-8-(1-ethylpropyl)-2,6-dimethyl-imidazo[1,2-b]pyridazine: a novel brain-penetrant, orally available corticotropin-releasing factor receptor 1 antagonist with efficacy in animal models of alcoholism.

21 January 2018

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Neurokinin 1 receptor antagonism as a possible therapy for alcoholism

21 January 2018

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Rimonabant (SR141716) has no effect on alcohol self-administration or endocrine measures in nontreatment-seeking heavy alcohol drinkers

21 January 2018

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Modulation of brain response to emotional images by alcohol cues in alcohol-dependent patients

21 January 2018

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Effects of β-adrenoceptor antagonists on alcohol drinking by alcohol-dependent rats.

21 January 2018

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Effects of CRF1-receptor and opioid-receptor antagonists on dependence-induced increases in alcohol drinking by alcohol-preferring (P) rats

21 January 2018

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Operant behavior and alcohol levels in blood and brain of alcohol-dependent rats

21 January 2018

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A randomised, double-blind, placebo-controlled, efficacy study of nalmefene, as-needed use, in patients with alcohol dependence.

21 January 2018

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Variation at the rat Crhr1 locus and sensitivity to relapse into alcohol seeking induced by environmental stress

21 January 2018

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Genetic impairment of frontocortical endocannabinoid degradation and high alcohol preference

21 January 2018

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Changes in the basal dendrites of cortical pyramidal cells from alcoholic patients--a quantitative Golgi study

21 January 2018

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A key role for corticotropin-releasing factor in alcohol dependence

21 January 2018

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Corticotropin-releasing factor and neuropeptide Y: role in emotional integration

21 January 2018

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Acute withdrawal, protracted abstinence and negative affect in alcoholism: are they linked?

21 January 2018

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Pharmacogenetic approaches to the treatment of alcohol addiction

21 January 2018

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Corticotropin-releasing factor in brain: a role in activation, arousal, and affect regulation.

21 January 2018

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Translational magnetic resonance spectroscopy reveals excessive central glutamate levels during alcohol withdrawal in humans and rats

21 January 2018

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Chronic acamprosate eliminates the alcohol deprivation effect while having limited effects on baseline responding for ethanol in rats.

21 January 2018

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Neuropeptide systems as novel therapeutic targets for depression and anxiety disorders

21 January 2018

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Chronic alcohol remodels prefrontal neurons and disrupts NMDAR-mediated fear extinction encoding

21 January 2018

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Glutamatergic targets for new alcohol medications

21 January 2018

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The adenosine A2A receptor agonist CGS 21680 decreases ethanol self-administration in both non-dependent and dependent animals

21 January 2018

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21 January 2018

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Update on neuropharmacological treatments for alcoholism: scientific basis and clinical findings

21 January 2018

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Genetic variation in the atrial natriuretic peptide transcription factor GATA4 modulates amygdala responsiveness in alcohol dependence.

21 January 2018

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Neuropeptide YY(2)R blockade in the central amygdala reduces anxiety-like behavior but not alcohol drinking in alcohol-dependent rats.

21 January 2018

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Alcohol intake as a risk factor for fracture

21 January 2018

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Transition to addiction is associated with a persistent impairment in synaptic plasticity

21 January 2018

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Involvement of the atrial natriuretic peptide transcription factor GATA4 in alcohol dependence, relapse risk and treatment response to acamprosate

21 January 2018

1 reference

The one-two punch of alcoholism: role of central amygdala dynorphins/kappa-opioid receptors

21 January 2018

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Corticotropin-releasing factor, norepinephrine, and stress

21 January 2018

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A role for brain stress systems in addiction

21 January 2018

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Drug abuse: hedonic homeostatic dysregulation

21 January 2018

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Drug addiction, dysregulation of reward, and allostasis

21 January 2018

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Addiction and the brain antireward system

21 January 2018

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Chronic alcohol exposure alters behavioral and synaptic plasticity of the rodent prefrontal cortex

21 January 2018

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Enhanced sensitivity to attenuation of conditioned reinstatement by the mGluR 2/3 agonist LY379268 and increased functional activity of mGluR 2/3 in rats with a history of ethanol dependence

21 January 2018

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Effects of naltrexone and fluoxetine on alcohol self-administration and reinstatement of alcohol seeking induced by priming injections of alcohol and exposure to stress.

21 January 2018

1 reference

Metabotropic glutamate 2/3 receptors in the ventral tegmental area and the nucleus accumbens shell are involved in behaviors relating to nicotine dependence.

21 January 2018

1 reference

The increased ethanol preference in rats induced by choice, darkness, or drugs is reduced by ritanserin

21 January 2018

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Reversal of ethanol-seeking behavior by D1 and D2 antagonists in an animal model of relapse: differences in antagonist potency in previously ethanol-dependent versus nondependent rats

21 January 2018

1 reference

Treating alcohol withdrawal with oral baclofen: a randomized, double-blind, placebo-controlled trial.

21 January 2018

1 reference

The CRF1 receptor antagonist antalarmin attenuates yohimbine-induced increases in operant alcohol self-administration and reinstatement of alcohol seeking in rats.

21 January 2018

1 reference

Neurobiological similarities in depression and drug dependence: a self-medication hypothesis

21 January 2018

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Role of innate and drug-induced dysregulation of brain stress and arousal systems in addiction: Focus on corticotropin-releasing factor, nociceptin/orphanin FQ, and orexin/hypocretin

21 January 2018

1 reference

Pharmacological management of alcohol withdrawal. A meta-analysis and evidence-based practice guideline. American Society of Addiction Medicine Working Group on Pharmacological Management of Alcohol Withdrawal

21 January 2018

1 reference

Central nervous system mechanisms in alcohol relapse

21 January 2018

1 reference

Ritanserin Reduces Abuse of Alcohol, Cocaine, and Fentanyl in Rats

21 January 2018

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Rescue of infralimbic mGluR2 deficit restores control over drug-seeking behavior in alcohol dependence

21 January 2018

1 reference

Brain region-specific gene expression changes after chronic intermittent ethanol exposure and early withdrawal in C57BL/6J mice

21 January 2018

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Brain-specific inactivation of the Crhr1 gene inhibits post-dependent and stress-induced alcohol intake, but does not affect relapse-like drinking

21 January 2018

1 reference

Rewarding effects of opiates are absent in mice lacking the receptor for substance P.

21 January 2018

1 reference

H2 haplotype at chromosome 17q21.31 protects against childhood sexual abuse-associated risk for alcohol consumption and dependence

21 January 2018

1 reference

Cluster and meta-analyses on factors influencing stress-induced alcohol drinking and relapse in rodents

21 January 2018

1 reference

Treatment of depression in patients with alcohol or other drug dependence: a meta-analysis

21 January 2018

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Fluoxetine, desipramine, and the dual antidepressant milnacipran reduce alcohol self-administration and/or relapse in dependent rats

21 January 2018

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Enhanced alcohol self-administration after intermittent versus continuous alcohol vapor exposure

21 January 2018

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Modulating the endocannabinoid system in human health and disease--successes and failures

21 January 2018

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Long-lasting suppression of alcohol preference in rats following serotonin receptor blockade by ritanserin.

21 January 2018

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A genetic determinant of the striatal dopamine response to alcohol in men

21 January 2018

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Glutamatergic and dopaminergic neurons mediate anxiogenic and anxiolytic effects of CRHR1.

21 January 2018

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Evaluation of a simple model of ethanol drinking to intoxication in C57BL/6J mice

21 January 2018

1 reference

A randomized controlled trial of adding the nicotine patch to rimonabant for smoking cessation: efficacy, safety and weight gain

21 January 2018

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Long-lasting increase in voluntary ethanol consumption and transcriptional regulation in the rat brain after intermittent exposure to alcohol

21 January 2018

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Suppression of ethanol self-administration by the neuropeptide Y (NPY) Y2 receptor antagonist BIIE0246: evidence for sensitization in rats with a history of dependence

21 January 2018

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Long-lasting tolerance to alcohol following a history of dependence.

21 January 2018

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Excessive ethanol drinking following a history of dependence: animal model of allostasis

21 January 2018

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The metabotropic glutamate 2/3 receptor agonist LY404039 reduces alcohol-seeking but not alcohol self-administration in alcohol-preferring (P) rats

21 January 2018

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Long-term ethanol administration methods for rats: advantages of inhalation over intubation or liquid diets

21 January 2018

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Brain and peripheral angiotensin II play a major role in stress

21 January 2018

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Behavioural assessment of drug reinforcement and addictive features in rodents: an overview.

21 January 2018

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Survival of AA and ANA rats during lifelong ethanol exposure

21 January 2018

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Stress-induced reinstatement of alcohol-seeking in rats is selectively suppressed by the neurokinin 1 (NK1) antagonist L822429.

21 January 2018

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Tacr1 gene variation and neurokinin 1 receptor expression is associated with antagonist efficacy in genetically selected alcohol-preferring rats

21 January 2018

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Induction of corticotropin-releasing hormone gene expression by glucocorticoids: implication for understanding the states of fear and anxiety and allostatic load

21 January 2018

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The effects of the mGluR5 antagonist MPEP and the mGluR2/3 antagonist LY341495 on rats' performance in the 5-choice serial reaction time task

21 January 2018

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Dihydromyricetin as a novel anti-alcohol intoxication medication.

21 January 2018

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Effects of the mGlu2/3 agonist LY379268 and the mGlu5 antagonist MTEP on ethanol seeking and reinforcement are differentially altered in rats with a history of ethanol dependence

21 January 2018

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A pilot trial of the alpha-1 adrenergic antagonist, prazosin, for alcohol dependence

21 January 2018

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The search for candidate genes of alcoholism: evidence from expression profiling studies.

21 January 2018

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The alcohol-preferring AA and alcohol-avoiding ANA rats: neurobiology of the regulation of alcohol drinking

21 January 2018

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Targeting brain angiotensin and corticotrophin-releasing hormone systems interaction for the treatment of mood and alcohol use disorders

21 January 2018

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Plasticity and impact of the central renin–angiotensin system during development of ethanol dependence

21 January 2018

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Upregulation of voluntary alcohol intake, behavioral sensitivity to stress, and amygdala crhr1 expression following a history of dependence

21 January 2018

1 reference

Cannabinoid receptor 1 blocker rimonabant (SR 141716) for treatment of alcohol dependence: results from a placebo-controlled, double-blind trial

21 January 2018

1 reference

Alcoholism: A Systems Approach From Molecular Physiology to Addictive Behavior

21 January 2018

1 reference

The dopamine hypothesis of reward: past and current status

21 January 2018

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Varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, selectively decreases ethanol consumption and seeking

21 January 2018

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Coordinated dysregulation of mRNAs and microRNAs in the rat medial prefrontal cortex following a history of alcohol dependence

21 January 2018

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Intermittent exposure to ethanol vapor affects osteoblast behaviour more severely than estrogen deficiency does in vitro study on rat osteoblasts

21 January 2018

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Genetic association of the human corticotropin releasing hormone receptor 1 (CRHR1) with binge drinking and alcohol intake patterns in two independent samples.

21 January 2018

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Translational approach to develop novel medications on alcohol addiction: focus on neuropeptides.

21 January 2018

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Effect of acamprosate on magnetic resonance spectroscopy measures of central glutamate in detoxified alcohol-dependent individuals: a randomized controlled experimental medicine study

21 January 2018

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Antagonism of corticotropin-releasing factor attenuates the enhanced responsiveness to stress observed during protracted ethanol abstinence

21 January 2018

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Corticosteroid-dependent plasticity mediates compulsive alcohol drinking in rats

21 January 2018

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The effects of lamotrigine on alcohol seeking and relapse

21 January 2018

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The gamma-aminobutyric acid-B receptor agonist baclofen attenuates responding for ethanol in ethanol-dependent rats

21 January 2018

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Pharmacological evidence for a motivational role of kappa-opioid systems in ethanol dependence

21 January 2018

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alpha1-noradrenergic receptor antagonism blocks dependence-induced increases in responding for ethanol

21 January 2018

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Systemic κ-opioid receptor antagonism by nor-binaltorphimine reduces dependence-induced excessive alcohol self-administration in rats

21 January 2018

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Animal models of addiction: models for therapeutic strategies?

21 January 2018

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Activation of group II metabotropic glutamate receptors attenuates both stress and cue-induced ethanol-seeking and modulates c-fos expression in the hippocampus and amygdala.

21 January 2018

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Loss of metabotropic glutamate receptor 2 escalates alcohol consumption

21 January 2018

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Behavioral, biological, and chemical perspectives on targeting CRF(1) receptor antagonists to treat alcoholism

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/ADB.12187

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1 September 2017

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