(Q38348602)

2 September 2017

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title

CRISPR genome engineering and viral gene delivery: a case of mutual attraction (English)

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2 September 2017

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2

Dirk Grimm

1 reference

2 September 2017

Florian Schmidt

1

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PubMed ID

25663455

2 September 2017

language of work or name

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6 February 2015

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2 September 2017

Biotechnology Journal

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2 September 2017

10

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2 September 2017

2

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2 September 2017

258-272

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Strategies for silencing human disease using RNA interference

2 September 2017

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Therapeutic application of RNAi: is mRNA targeting finally ready for prime time?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

The dose can make the poison: lessons learned from adverse in vivo toxicities caused by RNAi overexpression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

TALE nucleases: tailored genome engineering made easy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

TALENs: a widely applicable technology for targeted genome editing

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Development of nuclease-mediated site-specific genome modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Genome engineering with targetable nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Development and applications of CRISPR-Cas9 for genome engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Genome editing. The new frontier of genome engineering with CRISPR-Cas9

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

CRISPR-Cas systems for editing, regulating and targeting genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Gene therapy finds its niche

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Progress and problems with the use of viral vectors for gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Engineering targeted viral vectors for gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Effect of genome size on AAV vector packaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

From virus evolution to vector revolution: use of naturally occurring serotypes of adeno-associated virus (AAV) as novel vectors for human gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

CRISPR/Cas9-mediated genome engineering: an adeno-associated viral (AAV) vector toolbox

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

In vivo interrogation of gene function in the mammalian brain using CRISPR-Cas9

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Optimizing promoters for recombinant adeno-associated virus-mediated gene expression in the peripheral and central nervous system using self-complementary vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Self-complementary recombinant adeno-associated virus (scAAV) vectors promote efficient transduction independently of DNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

CRISPR-Cas9 knockin mice for genome editing and cancer modeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Viral vectors: from virology to transgene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Effective high-capacity gutless adenoviral vectors mediate transgene expression in human glioma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Genome-scale CRISPR-Cas9 knockout screening in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Efficient gene editing in adult mouse livers via adenoviral delivery of CRISPR/Cas9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Repurposing CRISPR/Cas9 for in situ functional assays.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Multiplex CRISPR/Cas9-based genome engineering from a single lentiviral vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Lentiviral vector design for multiple shRNA expression and durable HIV-1 inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Production methods for gene transfer vectors based on adeno-associated virus serotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Lentiviral vectors: turning a deadly foe into a therapeutic agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Gene therapy: trials and tribulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Uncovering and dissecting the genotoxicity of self-inactivating lentiviral vectors in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Retroviral integrations in gene therapy trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Current status of haemophilia gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Long-term correction of inhibitor-prone hemophilia B dogs treated with liver-directed AAV2-mediated factor IX gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

E-CRISP: fast CRISPR target site identification.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

New recombinant serotypes of AAV vectors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Engineering adeno-associated viruses for clinical gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

In vitro and in vivo gene therapy vector evolution via multispecies interbreeding and retargeting of adeno-associated viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

DNA shuffling of adeno-associated virus yields functionally diverse viral progeny

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Engineering and selection of shuffled AAV genomes: a new strategy for producing targeted biological nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Directed evolution of a novel adeno-associated virus (AAV) vector that crosses the seizure-compromised blood-brain barrier (BBB).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Random peptide libraries displayed on adeno-associated virus to select for targeted gene therapy vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Genetic modifications of the adeno-associated virus type 2 capsid reduce the affinity and the neutralizing effects of human serum antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Dual-regulated lentiviral vector for gene therapy of X-linked chronic granulomatosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Liver-specific microRNA-122 target sequences incorporated in AAV vectors efficiently inhibits transgene expression in the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Exploiting and antagonizing microRNA regulation for therapeutic and experimental applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Multiplexed and programmable regulation of gene networks with an integrated RNA and CRISPR/Cas toolkit in human cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Adenoviral vector delivery of RNA-guided CRISPR/Cas9 nuclease complexes induces targeted mutagenesis in a diverse array of human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Adenoviral vector DNA for accurate genome editing with engineered nucleases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

High-throughput screening of a CRISPR/Cas9 library for functional genomics in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Genetic screens in human cells using the CRISPR-Cas9 system

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Permanent alteration of PCSK9 with in vivo CRISPR-Cas9 genome editing

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

A microRNA-regulated lentiviral vector mediates stable correction of hemophilia B mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Endogenous microRNA regulation suppresses transgene expression in hematopoietic lineages and enables stable gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Generation of mouse models of myeloid malignancy with combinatorial genetic lesions using CRISPR-Cas9 genome editing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Engineering human tumour-associated chromosomal translocations with the RNA-guided CRISPR-Cas9 system

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Targeted genomic rearrangements using CRISPR/Cas technology

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Simple and rapid in vivo generation of chromosomal rearrangements using CRISPR/Cas9 technology

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

In vivo engineering of oncogenic chromosomal rearrangements with the CRISPR/Cas9 system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Targeted inversion and reversion of the blood coagulation factor 8 gene in human iPS cells using TALENs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Harnessing the CRISPR/Cas9 system to disrupt latent HIV-1 provirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Drawing a high-resolution functional map of adeno-associated virus capsid by massively parallel sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Tropism modification of adenovirus vectors by peptide ligand insertion into various positions of the adenovirus serotype 41 short-fiber knob domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Improving CRISPR-Cas nuclease specificity using truncated guide RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

Engineering light-inducible nuclear localization signals for precise spatiotemporal control of protein dynamics in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

In vivo gene regulation using tetracycline-regulatable systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIOT.201400529

21 January 2018

Identifiers

DOI

10.1002/BIOT.201400529

1 reference

2 September 2017

1 reference

PubMed ID

25663455