(Q38383985)

2 September 2017

1 reference

title

A review on protein-protein interaction network of APE1/Ref-1 and its associated biological functions (English)

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protein-protein interaction

2 September 2017

main subject

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3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25790058%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

author name string

S Thakur

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25790058%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

M Dhiman

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25790058%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

A K Mantha

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25790058%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

publication date

19 March 2015

1 reference

Cell Biochemistry & Function

2 September 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25790058%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

volume

33

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25790058%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25790058%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

page(s)

101-112

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25790058%20AND%20SRC:MED&resulttype=core&format=json

DNA Damage, Aging, and Cancer

6 June 2020

cites work

1 reference

DNA repair proteins as molecular targets for cancer therapeutics

21 January 2018

1 reference

Contribution of DNA repair mechanisms to determining chemotherapy response in high-grade glioma

21 January 2018

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The DNA-damage response in human biology and disease

21 January 2018

1 reference

DNA repair pathways as targets for cancer therapy

21 January 2018

1 reference

Cancer-specific defects in DNA repair pathways as targets for personalized therapeutic approaches

21 January 2018

1 reference

APE1/Ref-1 as an emerging therapeutic target for various human diseases: phytochemical modulation of its functions

21 January 2018

1 reference

A short review on the implications of base excision repair pathway for neurons: relevance to neurodegenerative diseases

21 January 2018

1 reference

Oxidative genome damage and its repair: implications in aging and neurodegenerative diseases.

21 January 2018

1 reference

Mechanisms of double-strand break repair in somatic mammalian cells

21 January 2018

1 reference

Molecular views of recombination proteins and their control

21 January 2018

1 reference

The multifaceted mismatch-repair system

21 January 2018

1 reference

Repair of endogenous DNA damage

21 January 2018

1 reference

The DNA Damage Response: Making It Safe to Play with Knives

21 January 2018

1 reference

A chemical and kinetic perspective on base excision repair of DNA.

21 January 2018

1 reference

Complexities of the DNA base excision repair pathway for repair of oxidative DNA damage

21 January 2018

1 reference

Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells

21 January 2018

1 reference

Inherited variants of MYH associated with somatic G:C-->T:A mutations in colorectal tumors

21 January 2018

1 reference

Mutations in OGG1, a gene involved in the repair of oxidative DNA damage, are found in human lung and kidney tumours

21 January 2018

1 reference

Association of genetic polymorphisms in the base excision repair pathway with lung cancer risk: a meta-analysis

21 January 2018

1 reference

Polymorphisms in base-excision repair and nucleotide-excision repair genes in relation to lung cancer risk.

21 January 2018

1 reference

Genetic polymorphisms in base-excision repair pathway genes and risk of breast cancer.

21 January 2018

1 reference

Pathways to motor incoordination: the inherited ataxias

21 January 2018

1 reference

Functional characterization of Ape1 variants identified in the human population

21 January 2018

1 reference

The DNA base excision repair protein Ape1/Ref-1 as a therapeutic and chemopreventive target

21 January 2018

1 reference

The many functions of APE1/Ref-1: not only a DNA repair enzyme

21 January 2018

1 reference

Repair of oxidative damage to DNA: enzymology and biology

21 January 2018

1 reference

APE1 is the major 3'-phosphoglycolate activity in human cell extracts

21 January 2018

1 reference

The role of Mg2+ and specific amino acid residues in the catalytic reaction of the major human abasic endonuclease: new insights from EDTA-resistant incision of acyclic abasic site analogs and site-directed mutagenesis.

21 January 2018

1 reference

A "moving metal mechanism" for substrate cleavage by the DNA repair endonuclease APE-1.

21 January 2018

1 reference

Unusual role of a cysteine residue in substrate binding and activity of human AP-endonuclease 1.

21 January 2018

1 reference

Transcriptional regulatory functions of mammalian AP-endonuclease (APE1/Ref-1), an essential multifunctional protein

21 January 2018

1 reference

A new APE1/Ref-1-dependent pathway leading to reduction of NF-kappaB and AP-1, and activation of their DNA-binding activity

21 January 2018

1 reference

The intracellular localization of APE1/Ref-1: more than a passive phenomenon?

21 January 2018

1 reference

Ref-1 regulates the transactivation and pro-apoptotic functions of p53 in vivo.

21 January 2018

1 reference

APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process.

21 January 2018

1 reference

Identification of Apurinic/apyrimidinic endonuclease 1 (APE1) as the endoribonuclease that cleaves c-myc mRNA

21 January 2018

1 reference

Dysregulation of human apurinic/apyrimidinic endonuclease 1 (APE1) expression in advanced retinoblastoma.

21 January 2018

1 reference

Alteration of APE1/ref-1 expression in non-small cell lung cancer: the implications of impaired extracellular superoxide dismutase and catalase antioxidant systems.

21 January 2018

1 reference

Downregulation of APE1/Ref-1 is involved in the senescence of mesenchymal stem cells.

21 January 2018

1 reference

Human AP endonuclease 1 (APE1): from mechanistic insights to druggable target in cancer.

21 January 2018

1 reference

Targeting base excision repair for chemosensitization

21 January 2018

1 reference

Emerging roles of the nucleolus in regulating the DNA damage response: the noncanonical DNA repair enzyme APE1/Ref-1 as a paradigmatical example

21 January 2018

1 reference

Protein-protein interactions and posttranslational modifications in mammalian base excision repair

21 January 2018

1 reference

Association of CBP/p300 acetylase and thymine DNA glycosylase links DNA repair and transcription

21 January 2018

1 reference

Human homolog of the MutY repair protein (hMYH) physically interacts with proteins involved in long patch DNA base excision repair

21 January 2018

1 reference

Coordination of steps in single-nucleotide base excision repair mediated by apurinic/apyrimidinic endonuclease 1 and DNA polymerase beta

21 January 2018

1 reference

XRCC1 coordinates the initial and late stages of DNA abasic site repair through protein-protein interactions

21 January 2018

1 reference

AP endonuclease and poly(ADP-ribose) polymerase-1 interact with the same base excision repair intermediate.

21 January 2018

1 reference

Interaction of human AP endonuclease 1 with flap endonuclease 1 and proliferating cell nuclear antigen involved in long-patch base excision repair

21 January 2018

1 reference

AP endonuclease 1 coordinates flap endonuclease 1 and DNA ligase I activity in long patch base excision repair

21 January 2018

1 reference

Distinct roles of Ape1 protein in the repair of DNA damage induced by ionizing radiation or bleomycin

21 January 2018

1 reference

Processing of bistranded abasic DNA clusters in gamma-irradiated human hematopoietic cells

21 January 2018

1 reference

Formation of clustered DNA damage after high-LET irradiation: a review

21 January 2018

1 reference

Mechanism of cluster DNA damage repair in response to high-atomic number and energy particles radiation

21 January 2018

1 reference

A fast Monte Carlo algorithm to simulate the spectrum of DNA damages formed by ionizing radiation.

21 January 2018

1 reference

Distinct roles of Ape1 protein, an enzyme involved in DNA repair, in high or low linear energy transfer ionizing radiation-induced cell killing

21 January 2018

1 reference

The DNA repair protein NBS1 influences the base excision repair pathway

21 January 2018

1 reference

Regulation of signal transducer and activator of transcription 3 enhanceosome formation by apurinic/apyrimidinic endonuclease 1 in hepatic acute phase response

21 January 2018

1 reference

Oxidoreductive modification of two cysteine residues in paired domain by Ref-1 regulates DNA-binding activity of Pax-8

21 January 2018

1 reference

Molecular mechanisms of transcription activation by HLF and HIF1alpha in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300.

21 January 2018

1 reference

Distinct roles of thioredoxin in the cytoplasm and in the nucleus. A two-step mechanism of redox regulation of transcription factor NF-kappaB.

21 January 2018

1 reference

Characterization of the DNA-binding properties of the early growth response-1 (Egr-1) transcription factor: evidence for modulation by a redox mechanism

21 January 2018

1 reference

Apurinic/apyrimidinic endonuclease 1 alters estrogen receptor activity and estrogen-responsive gene expression

21 January 2018

1 reference

Evolution of the redox function in mammalian apurinic/apyrimidinic endonuclease

21 January 2018

1 reference

Identification of residues in the human DNA repair enzyme HAP1 (Ref-1) that are essential for redox regulation of Jun DNA binding

21 January 2018

1 reference

DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected]

21 January 2018

1 reference

Differential expression of the apurinic / apyrimidinic endonuclease (APE/ref-1) multifunctional DNA base excision repair gene during fetal development and in adult rat brain and testis

21 January 2018

1 reference

Oxidative damage and reduction of redox factor-1 expression after transient spinal cord ischemia in rabbits

21 January 2018

1 reference

Modulation of DNA base excision repair during neuronal differentiation

21 January 2018

1 reference

Implications of apurinic/apyrimidinic endonuclease in reactive oxygen signaling response after cisplatin treatment of dorsal root ganglion neurons

21 January 2018

1 reference

Neurons efficiently repair glutamate-induced oxidative DNA damage by a process involving CREB-mediated up-regulation of apurinic endonuclease 1.

21 January 2018

1 reference

The repair function of the multifunctional DNA repair/redox protein APE1 is neuroprotective after ionizing radiation

21 January 2018

1 reference

Role of APE1 in differentiated neuroblastoma SH-SY5Y cells in response to oxidative stress: use of APE1 small molecule inhibitors to delineate APE1 functions

21 January 2018

1 reference

Role of the DNA base excision repair protein, APE1 in cisplatin, oxaliplatin, or carboplatin induced sensory neuropathy

21 January 2018

1 reference

Proteomic study of amyloid beta (25-35) peptide exposure to neuronal cells: Impact on APE1/Ref-1's protein-protein interaction

21 January 2018

1 reference

The redox function of APE1 is involved in the differentiation process of stem cells toward a neuronal cell fate.

21 January 2018

1 reference

Intrusion of a DNA repair protein in the RNome world: is this the beginning of a new era?

21 January 2018

1 reference

Nucleophosmin is essential for ribosomal protein L5 nuclear export

21 January 2018

1 reference

Critical lysine residues within the overlooked N-terminal domain of human APE1 regulate its biological functions.

21 January 2018

1 reference

Functional regulation of the apurinic/apyrimidinic endonuclease 1 by nucleophosmin: impact on tumor biology.

21 January 2018

1 reference

Nucleophosmin modulates stability, activity, and nucleolar accumulation of base excision repair proteins.

21 January 2018

1 reference

Regulation of WRN helicase activity in human base excision repair

21 January 2018

1 reference

Regulatory role of human AP-endonuclease (APE1/Ref-1) in YB-1-mediated activation of the multidrug resistance gene MDR1.

21 January 2018

1 reference

SIRT1 gene expression upon genotoxic damage is regulated by APE1 through nCaRE-promoter elements.

21 January 2018

1 reference

SIRT1 deacetylates APE1 and regulates cellular base excision repair

21 January 2018

1 reference

Genome-wide analysis and proteomic studies reveal APE1/Ref-1 multifunctional role in mammalian cells.

21 January 2018

1 reference

An 'environment to nucleus' signaling system operates in B lymphocytes: redox status modulates BSAP/Pax-5 activation through Ref-1 nuclear translocation

21 January 2018

1 reference

CD40 stimulation induces Pax5/BSAP and EBF activation through a APE/Ref-1-dependent redox mechanism

21 January 2018

1 reference

Tumor necrosis factor (TNF)-alpha-induced IL-8 expression in gastric epithelial cells: role of reactive oxygen species and AP endonuclease-1/redox factor (Ref)-1.

21 January 2018

1 reference

Apurinic/apyrimidinic endonuclease 1 is a key modulator of keratinocyte inflammatory responses

21 January 2018

1 reference

A dual regulatory role of apurinic/apyrimidinic endonuclease 1/redox factor-1 in HMGB1-induced inflammatory responses

21 January 2018

1 reference

The adaptive imbalance in base excision-repair enzymes generates microsatellite instability in chronic inflammation.

21 January 2018

1 reference

Granzyme K degrades the redox/DNA repair enzyme Ape1 to trigger oxidative stress of target cells leading to cytotoxicity

21 January 2018

1 reference

Role of the multifunctional DNA repair and redox signaling protein Ape1/Ref-1 in cancer and endothelial cells: small-molecule inhibition of the redox function of Ape1

21 January 2018

1 reference

Inhibition of APE1/Ref-1 redox activity rescues human retinal pigment epithelial cells from oxidative stress and reduces choroidal neovascularization

21 January 2018

1 reference

Apurinic/apyrimidinic endonuclease 1 regulates endothelial NO production and vascular tone.

21 January 2018

1 reference

The Ape-1/Ref-1 redox antagonist E3330 inhibits the growth of tumor endothelium and endothelial progenitor cells: therapeutic implications in tumor angiogenesis.

21 January 2018

1 reference

Suppression of choroidal neovascularization through inhibition of APE1/Ref-1 redox activity

21 January 2018

1 reference

Heat shock protein 70 binds to human apurinic/apyrimidinic endonuclease and stimulates endonuclease activity at abasic sites

21 January 2018

1 reference

Human glyceraldehyde-3-phosphate dehydrogenase plays a direct role in reactivating oxidized forms of the DNA repair enzyme APE1.

21 January 2018

1 reference

Dual regulatory roles of human AP-endonuclease (APE1/Ref-1) in CDKN1A/p21 expression

21 January 2018

1 reference

A unified view of base excision repair: lesion-dependent protein complexes regulated by post-translational modification

21 January 2018

1 reference

Role of acetylated human AP-endonuclease (APE1/Ref-1) in regulation of the parathyroid hormone gene

21 January 2018

1 reference

Posttranslational modification of mammalian AP endonuclease (APE1).

21 January 2018

1 reference

The role of Cdk5-mediated apurinic/apyrimidinic endonuclease 1 phosphorylation in neuronal death

21 January 2018

1 reference

Acetylation of human AP-endonuclease 1, a critical enzyme in DNA repair and transcription regulation

21 January 2018

1 reference

Activation of APE/Ref-1 redox activity is mediated by reactive oxygen species and PKC phosphorylation

21 January 2018

1 reference

APE1/Ref-1 regulates PTEN expression mediated by Egr-1

21 January 2018

1 reference

Ubiquitination of mammalian AP endonuclease (APE1) regulated by the p53-MDM2 signaling pathway

21 January 2018

1 reference

Ubiquitination of human AP-endonuclease 1 (APE1) enhanced by T233E substitution and by CDK5.

21 January 2018

1 reference

Apurinic/apyrimidinic endonuclease 1 inhibits protein kinase C-mediated p66shc phosphorylation and vasoconstriction.

21 January 2018

1 reference

Interaction of human apurinic endonuclease and DNA polymerase beta in the base excision repair pathway

21 January 2018

1 reference

Human thymine DNA glycosylase binds to apurinic sites in DNA but is displaced by human apurinic endonuclease 1.

21 January 2018

1 reference

APE1/Ref-1 regulates STAT3 transcriptional activity and APE1/Ref-1-STAT3 dual-targeting effectively inhibits pancreatic cancer cell survival

21 January 2018

1 reference

Human AP endonuclease (APE1/Ref-1) and its acetylation regulate YB-1-p300 recruitment and RNA polymerase II loading in the drug-induced activation of multidrug resistance gene MDR1

21 January 2018

1 reference

Cleaving the oxidative repair protein Ape1 enhances cell death mediated by granzyme A

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/CBF.3100

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25790058%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

1 reference