(Q48196301)

9 February 2018

title

The role of Cdk5-mediated apurinic/apyrimidinic endonuclease 1 phosphorylation in neuronal death (English)

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9 February 2018

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En Huang

1

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9 February 2018

Dianbo Qu

2

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9 February 2018

Yi Zhang

3

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9 February 2018

Katerina Venderova

4

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9 February 2018

M Emdadul Haque

5

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9 February 2018

Maxime W C Rousseaux

6

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9 February 2018

Ruth S Slack

7

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9 February 2018

John M Woulfe

8

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9 February 2018

David S Park

9

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9 February 2018

publication date

16 May 2010

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9 February 2018

published in

Nature Cell Biology

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9 February 2018

volume

12

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9 February 2018

issue

6

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9 February 2018

page(s)

563-571

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9 February 2018

https://scigraph.springernature.com/pub.10.1038/ncb2058

exact match

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cites work

Going APE over ref-1.

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCB2058

Cdk5, a therapeutic target for Alzheimer's disease?

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCB2058

The Chk1/Cdc25A pathway as activators of the cell cycle in neuronal death induced by camptothecin.

21 January 2018

1 reference

12 December 2020

Deregulation of HDAC1 by p25/Cdk5 in neurotoxicity

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12 December 2020

Novel genetic tools reveal Cdk5's major role in Golgi fragmentation in Alzheimer's disease

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12 December 2020

Inhibiting transient protein-protein interactions: lessons from the Cdc25 protein tyrosine phosphatases

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12 December 2020

Mechanisms of disease: DNA repair defects and neurological disease

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12 December 2020

APAF1 is a key transcriptional target for p53 in the regulation of neuronal cell death.

1 reference

12 December 2020

Endogenous DNA abasic sites cause cell death in the absence of Apn1, Apn2 and Rad1/Rad10 in Saccharomyces cerevisiae

1 reference

12 December 2020

Base excision DNA repair defect in Gadd45a-deficient cells.

1 reference

12 December 2020

Microwave-stimulated recovery of myosin-V immunoreactivity from formalin-fixed, paraffin-embedded human CNS.

1 reference

12 December 2020

Cytoplasmic Pink1 activity protects neurons from dopaminergic neurotoxin MPTP.

1 reference

12 December 2020

ATF4-dependent oxidative induction of the DNA repair enzyme Ape1 counteracts arsenite cytotoxicity and suppresses arsenite-mediated mutagenesis

1 reference

12 December 2020

The multifunctional DNA repair/redox enzyme Ape1/Ref-1 promotes survival of neurons after oxidative stress

1 reference

12 December 2020

Purification and characterization of a novel proline-directed protein kinase from bovine brain.

1 reference

12 December 2020

The DNA base excision repair protein Ape1/Ref-1 as a therapeutic and chemopreventive target

1 reference

12 December 2020

Protection against methylation-induced cytotoxicity by DNA polymerase beta-dependent long patch base excision repair

1 reference

12 December 2020

Phosphorylation of ATM by Cdk5 mediates DNA damage signalling and regulates neuronal death

1 reference

12 December 2020

Decreased cyclin-dependent kinase 5 (cdk5) activity is accompanied by redistribution of cdk5 and cytoskeletal proteins and increased cytoskeletal protein phosphorylation in p35 null mice.

1 reference

12 December 2020

Altered intracellular redox status in Gaucher disease fibroblasts and impairment of adaptive response against oxidative stress

1 reference

12 December 2020

Cleaving the oxidative repair protein Ape1 enhances cell death mediated by granzyme A

1 reference

12 December 2020

The intracellular localization of APE1/Ref-1: more than a passive phenomenon?

1 reference

12 December 2020

Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration

1 reference

12 December 2020

Implications of apurinic/apyrimidinic endonuclease in reactive oxygen signaling response after cisplatin treatment of dorsal root ganglion neurons

1 reference

12 December 2020

The protein SET binds the neuronal Cdk5 activator p35nck5a and modulates Cdk5/p35nck5a activity

1 reference

12 December 2020

A mechanism-based cross-linker for the identification of kinase-substrate pairs

1 reference

12 December 2020

Calpain-regulated p35/cdk5 plays a central role in dopaminergic neuron death through modulation of the transcription factor myocyte enhancer factor 2.

1 reference

12 December 2020

Role of Cdk5-mediated phosphorylation of Prx2 in MPTP toxicity and Parkinson's disease.

1 reference

12 December 2020

Nuclear factor-(kappa)B modulates the p53 response in neurons exposed to DNA damage.

1 reference

12 December 2020

Cdk5 deregulation in the pathogenesis of Alzheimer's disease

1 reference

12 December 2020

Phosphorylation of huntingtin by cyclin-dependent kinase 5 is induced by DNA damage and regulates wild-type and mutant huntingtin toxicity in neurons.

1 reference

12 December 2020

Neurotoxicity induces cleavage of p35 to p25 by calpain

1 reference

12 December 2020

p35nck5a and cyclin-dependent kinase 5 colocalize in Lewy bodies of brains with Parkinson's disease.

1 reference

12 December 2020

A simplified system for generating recombinant adenoviruses

1 reference

12 December 2020

A family of human cdc2-related protein kinases

2 references

12 December 2020

Crossref

https://api.crossref.org/works/10.1038%2FNCB2058

7 January 2021

inferred from DOI database lookup

MPP+ selectively affects calcium homeostasis in mesencephalic cell cultures from embryonal C57/Bl6 mice

1 reference

12 December 2020

Isolation of a small molecule inhibitor of DNA base excision repair.

1 reference

12 December 2020

A vital role for Ape1/Ref1 protein in repairing spontaneous DNA damage in human cells.

1 reference

12 December 2020

Inhibition of calpains prevents neuronal and behavioral deficits in an MPTP mouse model of Parkinson's disease.

1 reference

12 December 2020

The involvement of DNA-damage and -repair defects in neurological dysfunction

1 reference

12 December 2020

Altered expression of Ape1/ref-1 in germ cell tumors and overexpression in NT2 cells confers resistance to bleomycin and radiation.

1 reference

12 December 2020

Cyclin-dependent kinase 5 is a mediator of dopaminergic neuron loss in a mouse model of Parkinson's disease

1 reference

12 December 2020

Cyclin-dependent kinase 5 mediates neurotoxin-induced degradation of the transcription factor myocyte enhancer factor 2.

1 reference

12 December 2020

1 reference

12 December 2020

c-Jun mediates axotomy-induced dopamine neuron death in vivo

1 reference

12 December 2020

Cdk5-Mediated Inhibition of the Protective Effects of Transcription Factor MEF2 in Neurotoxicity-Induced Apoptosis

1 reference

12 December 2020

Calpains mediate p53 activation and neuronal death evoked by DNA damage.

1 reference

12 December 2020

Highly sensitive apurinic/apyrimidinic site assay can detect spontaneous and chemically induced depurination under physiological conditions

1 reference

12 December 2020

Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress.

1 reference

12 December 2020

BAG5 inhibits parkin and enhances dopaminergic neuron degeneration

1 reference

12 December 2020

Evidence for p53-mediated modulation of neuronal viability.

1 reference

12 December 2020

Required roles of Bax and JNKs in central and peripheral nervous system death of retinoblastoma-deficient mice.

1 reference

12 December 2020

Stabilization and activation of p53 induced by Cdk5 contributes to neuronal cell death

1 reference

12 December 2020

The redox/DNA repair protein, Ref-1, is essential for early embryonic development in mice.

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCB2058

1 reference

9 February 2018

release_k3mwjf4qqjanlpuq7tutsziype

Fatcat ID

0 references

1 reference

9 February 2018