(Q38436818)

3 September 2017

title

Genetic and epigenetic changes in mammary epithelial cells identify a subpopulation of cells involved in early carcinogenesis (English)

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3 September 2017

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Berman H

1

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3 September 2017

Zhang J

2

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3 September 2017

Crawford YG

3

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3 September 2017

Gauthier ML

4

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3 September 2017

Fordyce CA

5

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3 September 2017

McDermott KM

6

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3 September 2017

Sigaroudinia M

7

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3 September 2017

Kozakiewicz K

8

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3 September 2017

Tlsty TD

9

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3 September 2017

publication date

1 January 2005

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Cold Spring Harbor Symposia on Quantitative Biology

3 September 2017

published in

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3 September 2017

volume

70

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3 September 2017

page(s)

317-327

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Distinctive traits of normal and tumor-derived human mammary epithelial cells expressed in a medium that supports long-term growth of both cell types

3 September 2017

cites work

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Normal human fibroblasts are resistant to RAS-induced senescence

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Extension of life-span by introduction of telomerase into normal human cells

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Increased p16 expression with first senescence arrest in human mammary epithelial cells and extended growth capacity with p16 inactivation

21 January 2018

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Histologically normal human mammary epithelia with silenced p16(INK4a) overexpress COX-2, promoting a premalignant program

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Loss of heterozygosity in normal tissue adjacent to breast carcinomas.

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A tentative classification of centrosome abnormalities in cancer

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The contributions of cyclooxygenase-2 to tumor angiogenesis

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Creation of human tumour cells with defined genetic elements

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Serum-free growth of human mammary epithelial cells: rapid clonal growth in defined medium and extended serial passage with pituitary extract

21 January 2018

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THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS

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Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

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Cyclooxygenase-2: a target for the prevention and treatment of breast cancer

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Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype

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Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

21 January 2018

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Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice

21 January 2018

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Centrosome amplification drives chromosomal instability in breast tumor development

21 January 2018

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Centrosome hypertrophy in human breast tumors: implications for genomic stability and cell polarity

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Growth suppression by p16ink4 requires functional retinoblastoma protein

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Susceptibility of nonpromoter CpG islands to de novo methylation in normal and neoplastic cells

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In situ detection of the hypermethylation-induced inactivation of the p16 gene as an early event in oncogenesis

21 January 2018

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Chromosome abnormalities in bilateral breast carcinomas. Cytogenetic evaluation of the clonal origin of multiple primary tumors.

21 January 2018

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Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions

21 January 2018

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Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes

21 January 2018

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The contribution of epigenetic changes to abnormal centrosomes and genomic instability in breast cancer

21 January 2018

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A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

21 January 2018

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Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis

21 January 2018

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Expression of the telomerase catalytic subunit, hTERT, induces resistance to transforming growth factor beta growth inhibition in p16INK4A(-) human mammary epithelial cells

21 January 2018

1 reference

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Differences in the rates of gene amplification in nontumorigenic and tumorigenic cell lines as measured by Luria-Delbrück fluctuation analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.051

Loss of chromosomal integrity in human mammary epithelial cells subsequent to escape from senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.051

Genetic and epigenetic changes in mammary epithelial cells may mimic early events in carcinogenesis

21 January 2018

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TRF2 Protects Human Telomeres from End-to-End Fusions

21 January 2018

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Chromosome analyses of human mammary epithelial cells at stages of chemical-induced transformation progression to immortality

21 January 2018

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Analysis of p16INK4aand Its Interaction with CDK4

21 January 2018

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21 January 2018

Identifiers

DOI

10.1101/SQB.2005.70.051

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3 September 2017

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