(Q38453659)

3 September 2017

1 reference

title

Construction of a functional thymic microenvironment from pluripotent stem cells for the induction of central tolerance (English)

1 reference

3 September 2017

1 reference

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25933240%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

author name string

Nicholas Bredenkamp

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25933240%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Xin Jin

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25933240%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Dong Liu

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25933240%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Kathy E O'Neill

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25933240%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Nancy R Manley

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25933240%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

publication date

1 January 2015

1 reference

3 September 2017

published in

Regenerative Medicine

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25933240%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

volume

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25933240%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25933240%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

page(s)

317-329

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25933240%20AND%20SRC:MED&resulttype=core&format=json

IMMUNOLOGICAL FUNCTION OF THE THYMUS

10 June 2020

cites work

1 reference

Positive and negative selection of the T cell repertoire: what thymocytes see (and don't see)

21 January 2018

1 reference

Thymic epithelial cells: working class heroes for T cell development and repertoire selection

21 January 2018

1 reference

Mechanisms of T cell development and transformation.

21 January 2018

1 reference

Transplantation of thymus tissue in complete DiGeorge syndrome

21 January 2018

1 reference

Exposing the human nude phenotype

21 January 2018

1 reference

AIRE and APECED: molecular insights into an autoimmune disease

21 January 2018

1 reference

Changes in primary lymphoid organs with aging

21 January 2018

1 reference

Aging of the immune system: how much can the adaptive immune system adapt?

21 January 2018

1 reference

Thymic involution and immune reconstitution.

21 January 2018

1 reference

Immune memory and aging: an infinite or finite resource?

21 January 2018

1 reference

Rejuvenation of the aging T cell compartment

21 January 2018

1 reference

The role of the thymus in immune reconstitution in aging, bone marrow transplantation, and HIV-1 infection

21 January 2018

1 reference

The challenge of immunogenicity in the quest for induced pluripotency.

21 January 2018

1 reference

Strategies to enhance T-cell reconstitution in immunocompromised patients

21 January 2018

1 reference

First use of thymus transplantation therapy for FOXN1 deficiency (nude/SCID): a report of 2 cases

21 January 2018

1 reference

Thymus transplantation in complete DiGeorge anomaly

21 January 2018

1 reference

Zoned out: functional mapping of stromal signaling microenvironments in the thymus

21 January 2018

1 reference

Commitment and developmental potential of extrathymic and intrathymic T cell precursors: plenty to choose from

21 January 2018

1 reference

Mapping precursor movement through the postnatal thymus reveals specific microenvironments supporting defined stages of early lymphoid development

21 January 2018

1 reference

Regulatory T cells: mechanisms of differentiation and function

21 January 2018

1 reference

Role of thymic organ structure and stromal composition in steady-state postnatal T-cell production

21 January 2018

1 reference

Differential contribution of chemotaxis and substrate restriction to segregation of immature and mature thymocytes

21 January 2018

1 reference

The thymic microenvironment.

21 January 2018

1 reference

Structure and function of the thymic microenvironment.

21 January 2018

1 reference

Foxn1 regulates lineage progression in cortical and medullary thymic epithelial cells but is dispensable for medullary sublineage divergence

21 January 2018

1 reference

Foxn1 is required to maintain the postnatal thymic microenvironment in a dosage-sensitive manner

21 January 2018

1 reference

MicroRNAs control the maintenance of thymic epithelia and their competence for T lineage commitment and thymocyte selection

21 January 2018

1 reference

Three-dimensional architecture of the thymus is required to maintain delta-like expression necessary for inducing T cell development.

21 January 2018

1 reference

Hematopoietic progenitor migration to the adult thymus

21 January 2018

1 reference

Developmental kinetics, turnover, and stimulatory capacity of thymic epithelial cells.

21 January 2018

1 reference

Delta-like 4 is indispensable in thymic environment specific for T cell development

21 January 2018

1 reference

Ongoing Dll4-Notch signaling is required for T-cell homeostasis in the adult thymus.

21 January 2018

1 reference

Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment.

21 January 2018

1 reference

Cutting edge: thymic crosstalk regulates delta-like 4 expression on cortical epithelial cells.

21 January 2018

1 reference

Homing of immature thymocytes to the subcapsular microenvironment within the thymus is not an absolute requirement for T cell development.

21 January 2018

1 reference

Stromal cell-derived factor 1α and CXCR4: newly defined requirements for efficient thymic β-selection

21 January 2018

1 reference

Thymoproteasome: probable role in generating positively selecting peptides

21 January 2018

1 reference

Thymoproteasome shapes immunocompetent repertoire of CD8+ T cells.

21 January 2018

1 reference

β5t-containing thymoproteasome: specific expression in thymic cortical epithelial cells and role in positive selection of CD8+ T cells

21 January 2018

1 reference

CCR7 signals are essential for cortex-medulla migration of developing thymocytes.

21 January 2018

1 reference

Lymphotoxin β receptor regulates the development of CCL21-expressing subset of postnatal medullary thymic epithelial cells.

21 January 2018

1 reference

Journey through the thymus: stromal guides for T-cell development and selection

21 January 2018

1 reference

T Cell Reactivity to MHC Molecules: Immunity Versus Tolerance

21 January 2018

1 reference

Intrathymic presentation of circulating non-MHC antigens by medullary dendritic cells. An antigen-dependent microenvironment for T cell differentiation

21 January 2018

1 reference

Projection of an immunological self shadow within the thymus by the aire protein

21 January 2018

1 reference

Self-representation in the thymus: an extended view

21 January 2018

1 reference

21 January 2018

1 reference

Aire's partners in the molecular control of immunological tolerance

21 January 2018

1 reference

Population and single-cell genomics reveal the Aire dependency, relief from Polycomb silencing, and distribution of self-antigen expression in thymic epithelia

21 January 2018

1 reference

Thymic medullary epithelial cell differentiation, thymocyte emigration, and the control of autoimmunity require lympho-epithelial cross talk via LTbetaR.

21 January 2018

1 reference

Regulatory T cell lineage specification by the forkhead transcription factor foxp3

21 January 2018

1 reference

Control of regulatory T cell lineage commitment and maintenance

21 January 2018

1 reference

Dynamics of thymus organogenesis and colonization in early human development

21 January 2018

1 reference

Functional evidence for a single endodermal origin for the thymic epithelium.

21 January 2018

1 reference

Clonal analysis reveals a common progenitor for thymic cortical and medullary epithelium

21 January 2018

1 reference

Formation of a functional thymus initiated by a postnatal epithelial progenitor cell.

21 January 2018

1 reference

Thymus medulla consisting of epithelial islets each derived from a single progenitor

21 January 2018

1 reference

Medullary thymic epithelial cells expressing Aire represent a unique lineage derived from cells expressing claudin.

21 January 2018

1 reference

Lymphotoxin signal promotes thymic organogenesis by eliciting RANK expression in the embryonic thymic stroma.

21 January 2018

1 reference

The tumor necrosis factor family receptors RANK and CD40 cooperatively establish the thymic medullary microenvironment and self-tolerance.

21 January 2018

1 reference

The cytokine RANKL produced by positively selected thymocytes fosters medullary thymic epithelial cells that express autoimmune regulator.

21 January 2018

1 reference

Developing a new paradigm for thymus organogenesis.

21 January 2018

1 reference

Transcriptional regulation of thymus organogenesis and thymic epithelial cell differentiation

21 January 2018

1 reference

Mechanisms of thymus organogenesis and morphogenesis

21 January 2018

1 reference

Evolution of genetic networks underlying the emergence of thymopoiesis in vertebrates.

21 January 2018

1 reference

Thymopoiesis in mice depends on a Foxn1-positive thymic epithelial cell lineage

21 January 2018

1 reference

Overexpression of Foxn1 attenuates age-associated thymic involution and prevents the expansion of peripheral CD4 memory T cells

21 January 2018

1 reference

Synergistic, context-dependent, and hierarchical functions of epithelial components in thymic microenvironments

21 January 2018

1 reference

Regeneration of the aged thymus by a single transcription factor.

21 January 2018

1 reference

Generation of anterior foregut endoderm from human embryonic and induced pluripotent stem cells.

21 January 2018

1 reference

Adult thymus contains FoxN1(-) epithelial stem cells that are bipotent for medullary and cortical thymic epithelial lineages

21 January 2018

1 reference

Long-term persistence of functional thymic epithelial progenitor cells in vivo under conditions of low FOXN1 expression

21 January 2018

1 reference

Insertional mutation of a gene involved in growth regulation of the early mouse embryo

21 January 2018

1 reference

Efficient differentiation of human embryonic stem cells to definitive endoderm

21 January 2018

1 reference

Development of definitive endoderm from embryonic stem cells in culture

21 January 2018

1 reference

Induction and monitoring of definitive and visceral endoderm differentiation of mouse ES cells

21 January 2018

1 reference

Anterior definitive endoderm from ESCs reveals a role for FGF signaling

21 January 2018

1 reference

Endodermal stem cell populations derived from pluripotent stem cells

21 January 2018

1 reference

Generation of multipotent foregut stem cells from human pluripotent stem cells

21 January 2018

1 reference

Modelling human development and disease in pluripotent stem-cell-derived gastric organoids

21 January 2018

1 reference

Efficient generation of lung and airway epithelial cells from human pluripotent stem cells

21 January 2018

1 reference

An in vivo model of human small intestine using pluripotent stem cells

21 January 2018

1 reference

21 January 2018

How to make an intestine

1 reference

Human intestinal tissue with adult stem cell properties derived from pluripotent stem cells

21 January 2018

1 reference

EpCAM is involved in maintenance of the murine embryonic stem cell phenotype

21 January 2018

1 reference

Generation of functional thymic epithelium from human embryonic stem cells that supports host T cell development

21 January 2018

1 reference

Directed differentiation of human embryonic stem cells into thymic epithelial progenitor-like cells reconstitutes the thymic microenvironment in vivo

21 January 2018

1 reference

FOXN1 (GFP/w) reporter hESCs enable identification of integrin-β4, HLA-DR, and EpCAM as markers of human PSC-derived FOXN1(+) thymic epithelial progenitors.

21 January 2018

1 reference

Multilineage potential and self-renewal define an epithelial progenitor cell population in the adult thymus.

21 January 2018

1 reference

Activation of muscle-specific genes in pigment, nerve, fat, liver, and fibroblast cell lines by forced expression of MyoD.

21 January 2018

1 reference

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

21 January 2018

1 reference

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

21 January 2018

1 reference

Reprogramming of committed T cell progenitors to macrophages and dendritic cells by C/EBP alpha and PU.1 transcription factors.

21 January 2018

1 reference

Direct conversion of human fibroblasts to multilineage blood progenitors.

21 January 2018

1 reference

Direct conversion of fibroblasts to functional neurons by defined factors

21 January 2018

1 reference

Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy

21 January 2018

1 reference

Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors

21 January 2018

1 reference

Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors

21 January 2018

1 reference

Direct conversion of mouse fibroblasts to hepatocyte-like cells by defined factors.

21 January 2018

1 reference

An organized and functional thymus generated from FOXN1-reprogrammed fibroblasts

21 January 2018

1 reference

Interleukin-22 drives endogenous thymic regeneration in mice

21 January 2018

1 reference

Cell migration and the control of post-natal T-cell lymphopoiesis in the thymus

21 January 2018

1 reference

Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment.

21 January 2018

1 reference

Notch signaling controls the generation and differentiation of early T lineage progenitors

21 January 2018

1 reference

Precursors of CD3+CD4+CD8+ cells in the human thymus are defined by expression of CD34. Delineation of early events in human thymic development

21 January 2018

1 reference

A glossary for stem-cell biology

21 January 2018

1 reference

Microenvironmental reprogramming of thymic epithelial cells to skin multipotent stem cells

21 January 2018

1 reference

Dynamics of Thymus-Colonizing Cells during Human Development

21 January 2018

1 reference

Induction of human neuronal cells by defined transcription factors

21 January 2018

1 reference

COCI

https://opencitations.net/index/coci/api/v1/citations/10.1038/NATURE10202

30 October 2021

Identifiers

DOI

10.2217/RME.15.8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25933240%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

1 reference