(Q34590391)

English

Population and single-cell genomics reveal the Aire dependency, relief from Polycomb silencing, and distribution of self-antigen expression in thymic epithelia

scientific article

In more languages

default values for all languages

No label defined

No description defined

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Population and single-cell genomics reveal the Aire dependency, relief from Polycomb silencing, and distribution of self-antigen expression in thymic epithelia (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

single cell transcriptomics

1 reference

A curated database reveals trends in single-cell transcriptomics

https://www.nxn.se/single-cell-studies/data.tsv

7 February 2021

0 references

7

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Iain C Macaulay

object named as

Iain C Macaulay

5

0 references

author name string

Stephen N Sansom

1

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Noriko Shikama-Dorn

2

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Saule Zhanybekova

3

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Gretel Nusspaumer

4

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Mary E Deadman

6

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Georg A Holländer

9

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

publication date

15 September 2014

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

external data available at URL

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE60297

1 reference

A curated database reveals trends in single-cell transcriptomics

https://www.nxn.se/single-cell-studies/data.tsv

7 February 2021

Genome Research

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

24

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

12

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

1918-1931

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

describes a project that uses

1 reference

A curated database reveals trends in single-cell transcriptomics

7 February 2021

https://www.nxn.se/single-cell-studies/data.tsv

The transcriptional regulator Aire coopts the repressive ATF7ip-MBD1 complex for the induction of immunotolerance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Elephant shark genome provides unique insights into gnathostome evolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

CGAT: computational genomics analysis toolkit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

From single-cell to cell-pool transcriptomes: stochasticity in gene expression and RNA splicing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Serial progression of cortical and medullary thymic epithelial microenvironments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

BPIFB1 is a lung-specific autoantigen associated with interstitial lung disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Autoimmune gastro-pancreatitis with anti-protein disulfide isomerase-associated 2 autoantibody in Aire-deficient BALB/cAnN mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Polycomb complexes in stem cells and embryonic development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Transcriptome sequencing of neonatal thymic epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Mechanisms of thymus medulla development and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Murine thymic selection quantified using a unique method to capture deleted T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

The mechanism of tissue-restricted antigen gene expression by AIRE.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Aire's plant homeodomain(PHD)-2 is critical for induction of immunological tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

AIRE-PHD fingers are structural hubs to maintain the integrity of chromatin-associated interactome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

MicroRNAs control the maintenance of thymic epithelia and their competence for T lineage commitment and thymocyte selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

An encyclopedia of mouse DNA elements (Mouse ENCODE).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Full-length mRNA-Seq from single-cell levels of RNA and individual circulating tumor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

T-cell tolerance: central and peripheral

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Thymic epithelial cells: working class heroes for T cell development and repertoire selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Aire promotes the self-renewal of embryonic stem cells through Lin28.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Plasmacytoid dendritic cells transport peripheral antigens to the thymus to promote central tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Unmodified histone H3K4 and DNA-dependent protein kinase recruit autoimmune regulator to target genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Whole-genome chromatin profiling from limited numbers of cells using nano-ChIP-seq

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Plant Homeodomain (PHD) Fingers of CHD4 Are Histone H3-binding Modules with Preference for Unmodified H3K4 and Methylated H3K9

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Thymus-specific serine protease contributes to the diversification of the functional endogenous CD4 T cell receptor repertoire

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Differential expression analysis for sequence count data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Epigenetic regulation of promiscuous gene expression in thymic medullary epithelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

How thymic antigen presenting cells sample the body's self-antigens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Global relevance of Aire binding to hypomethylated lysine-4 of histone-3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Fast and SNP-tolerant detection of complex variants and splicing in short reads

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Aire's partners in the molecular control of immunological tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

An abundance of ubiquitously expressed genes revealed by tissue transcriptome sequence data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Antigen presentation in the thymus for positive selection and central tolerance induction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

AIRE activated tissue specific genes have histone modifications associated with inactive chromatin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Binding of the CHD4 PHD2 finger to histone H3 is modulated by covalent modifications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Fast and accurate short read alignment with Burrows-Wheeler transform

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Structure and site-specific recognition of histone H3 by the PHD finger of human autoimmune regulator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Clearing the AIRE: on the pathophysiological basis of the autoimmune polyendocrinopathy syndrome type-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

TopHat: discovering splice junctions with RNA-Seq

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Clonal deletion of thymocytes can occur in the cortex with no involvement of the medulla

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Aire employs a histone-binding module to mediate immunological tolerance, linking chromatin regulation with organ-specific autoimmunity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Ectopic expression of peripheral-tissue antigens in the thymic epithelium: probabilistic, monoallelic, misinitiated

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Differentiation of regulatory Foxp3+ T cells in the thymic cortex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Deletional tolerance mediated by extrathymic Aire-expressing cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

TSCOT+ thymic epithelial cell-mediated sensitive CD4 tolerance by direct presentation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Mapping and quantifying mammalian transcriptomes by RNA-Seq

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Expression analysis of G Protein-Coupled Receptors in mouse macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Promiscuous gene expression patterns in single medullary thymic epithelial cells argue for a stochastic mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Evidence based selection of housekeeping genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Clonal deletion of thymocytes by circulating dendritic cells homing to the thymus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Cellular and molecular events during early thymus development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Proposed methods for testing and selecting the ERCC external RNA controls

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Contrasting models of promiscuous gene expression by thymic epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Promiscuous gene expression in thymic epithelial cells is regulated at multiple levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Self-representation in the thymus: an extended view

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Positive and negative selection of T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

Projection of an immunological self shadow within the thymus by the aire protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

7 July 2018

CHD6 chromatin remodeler is a negative modulator of influenza virus replication that relocates to inactive chromatin upon infection

1 reference

https://api.crossref.org/works/10.1101%2FGR.171645.113

21 January 2018

AIRE1A might be involved in cyclin B2 degradation in testicular lysates

1 reference

https://api.crossref.org/works/10.1101%2FGR.171645.113

21 January 2018

QVALITY: non-parametric estimation of q-values and posterior error probabilities

1 reference

https://api.crossref.org/works/10.1101%2FGR.171645.113

21 January 2018

Expression of Aire and the early wave of apoptosis in spermatogenesis

1 reference

https://api.crossref.org/works/10.1101%2FGR.171645.113

21 January 2018

Update on autoimmune polyendocrine syndromes (APS).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

27 October 2018

The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248310

9 December 2018

Role of PHD fingers and COOH-terminal 30 amino acids in AIRE transactivation activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/25224068

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autoantigen-Specific Interactions with CD4+ Thymocytes Control Mature Medullary Thymic Epithelial Cell Cellularity

1 reference

https://pubmed.ncbi.nlm.nih.gov/25224068

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lymphotoxin pathway and Aire influences on thymic medullary epithelial cells are unconnected

1 reference

https://pubmed.ncbi.nlm.nih.gov/25224068

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1101/GR.171645.113

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q34590391&oldid=1976310363"