(Q38459795)

3 September 2017

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title

The NSD family of protein methyltransferases in human cancer (English)

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3 September 2017

4

Vassiliki Saloura

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3 September 2017

author name string

Theodore Vougiouklakis

series ordinal

1

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3 September 2017

Ryuji Hamamoto

series ordinal

2

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3 September 2017

Yusuke Nakamura

series ordinal

3

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3 September 2017

publication date

5 May 2015

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3 September 2017

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3 September 2017

volume

7

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3 September 2017

issue

5

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3 September 2017

page(s)

863-874

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Understanding the language of Lys36 methylation at histone H3.

3 September 2017

cites work

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Mitotic-specific methylation of histone H4 Lys 20 follows increased PR-Set7 expression and its localization to mitotic chromosomes

21 January 2018

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Critical roles of non-histone protein lysine methylation in human tumorigenesis

21 January 2018

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Role for the nuclear receptor-binding SET domain protein 1 (NSD1) methyltransferase in coordinating lysine 36 methylation at histone 3 with RNA polymerase II function

21 January 2018

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High-resolution profiling of histone methylations in the human genome

21 January 2018

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Histone H3 lysine 36 methyltransferase Whsc1 promotes the association of Runx2 and p300 in the activation of bone-related genes

21 January 2018

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Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

21 January 2018

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NSD1 is essential for early post-implantation development and has a catalytically active SET domain

21 January 2018

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A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf-Hirschhorn syndrome

21 January 2018

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Substrate specificity analysis and novel substrates of the protein lysine methyltransferase NSD1.

21 January 2018

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Regulation of NF-kappaB by NSD1/FBXL11-dependent reversible lysine methylation of p65.

21 January 2018

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The target of the NSD family of histone lysine methyltransferases depends on the nature of the substrate

21 January 2018

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Two distinct nuclear receptor interaction domains in NSD1, a novel SET protein that exhibits characteristics of both corepressors and coactivators

21 January 2018

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A novel gene, NSD1, is fused to NUP98 in the t(5;11)(q35;p15.5) in de novo childhood acute myeloid leukemia.

21 January 2018

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Identification and characterization of a novel androgen receptor coregulator ARA267-alpha in prostate cancer cells

21 January 2018

1 reference

A clinical study of Sotos syndrome patients with review of the literature

21 January 2018

1 reference

Sotos syndrome is associated with deregulation of the MAPK/ERK-signaling pathway.

21 January 2018

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NUP98-NSD1 links H3K36 methylation to Hox-A gene activation and leukaemogenesis.

21 January 2018

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A rare but specific subset of adult AML patients can be defined by the cytogenetically cryptic NUP98-NSD1 fusion gene

21 January 2018

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Epigenetic inactivation of the Sotos overgrowth syndrome gene histone methyltransferase NSD1 in human neuroblastoma and glioma

21 January 2018

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Comprehensive genomic characterization of head and neck squamous cell carcinomas

21 January 2018

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Integrative analysis of head and neck cancer identifies two biologically distinct HPV and three non-HPV subtypes

21 January 2018

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The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data

21 January 2018

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WHSC1, a 90 kb SET domain-containing gene, expressed in early development and homologous to a Drosophila dysmorphy gene maps in the Wolf-Hirschhorn syndrome critical region and is fused to IgH in t(4;14) multiple myeloma

21 January 2018

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Histone lysine methyltransferase Wolf-Hirschhorn syndrome candidate 1 is involved in human carcinogenesis through regulation of the Wnt pathway

21 January 2018

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WHSC1 promotes oncogenesis through regulation of NIMA-related kinase-7 in squamous cell carcinoma of the head and neck.

21 January 2018

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Overexpression of MMSET in endometrial cancer: a clinicopathologic study

21 January 2018

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Overexpression of MMSET is correlation with poor prognosis in hepatocellular carcinoma

21 January 2018

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Overexpression of transcripts originating from the MMSET locus characterizes all t(4;14)(p16;q32)-positive multiple myeloma patients

21 January 2018

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A subset of multiple myeloma harboring the t(4;14)(p16;q32) translocation lacks FGFR3 expression but maintains an IGH/MMSET fusion transcript

21 January 2018

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The MMSET histone methyl transferase switches global histone methylation and alters gene expression in t(4;14) multiple myeloma cells.

21 January 2018

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NSD2 links dimethylation of histone H3 at lysine 36 to oncogenic programming

21 January 2018

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Point mutation E1099K in MMSET/NSD2 enhances its methyltranferase activity and leads to altered global chromatin methylation in lymphoid malignancies

21 January 2018

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Global chromatin profiling reveals NSD2 mutations in pediatric acute lymphoblastic leukemia

21 January 2018

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The histone methyltransferase MMSET/WHSC1 activates TWIST1 to promote an epithelial-mesenchymal transition and invasive properties of prostate cancer

21 January 2018

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Characterization of the EZH2-MMSET histone methyltransferase regulatory axis in cancer

21 January 2018

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Histone methyltransferase MMSET/NSD2 alters EZH2 binding and reprograms the myeloma epigenome through global and focal changes in H3K36 and H3K27 methylation

21 January 2018

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MMSET stimulates myeloma cell growth through microRNA-mediated modulation of c-MYC.

21 January 2018

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Histone methyltransferase NSD2/MMSET mediates constitutive NF-κB signaling for cancer cell proliferation, survival, and tumor growth via a feed-forward loop

21 January 2018

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MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites

21 January 2018

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Wolf-Hirschhorn syndrome candidate 1 is involved in the cellular response to DNA damage

21 January 2018

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NSD3, a new SET domain-containing gene, maps to 8p12 and is amplified in human breast cancer cell lines

21 January 2018

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Genetic alterations of histone lysine methyltransferases and their significance in breast cancer

21 January 2018

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Comprehensive profiling of 8p11-12 amplification in breast cancer

21 January 2018

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Genomic and expression analysis of the 8p11-12 amplicon in human breast cancer cell lines

21 January 2018

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Multiple interacting oncogenes on the 8p11-p12 amplicon in human breast cancer

21 January 2018

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Identification of druggable cancer driver genes amplified across TCGA datasets

21 January 2018

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NUP98 is fused to the NSD3 gene in acute myeloid leukemia associated with t(8;11)(p11.2;p15).

21 January 2018

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NUP98-NSD3 fusion gene in radiation-associated myelodysplastic syndrome with t(8;11)(p11;p15) and expression pattern of NSD family genes

21 January 2018

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Transforming properties of 8p11-12 amplified genes in human breast cancer

21 January 2018

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The histone methyltransferase Wolf-Hirschhorn syndrome candidate 1-like 1 (WHSC1L1) is involved in human carcinogenesis

21 January 2018

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The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3.

21 January 2018

1 reference

NSD3-NUT fusion oncoprotein in NUT midline carcinoma: implications for a novel oncogenic mechanism

21 January 2018

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RB1 methylation by SMYD2 enhances cell cycle progression through an increase of RB1 phosphorylation

21 January 2018

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Enhanced HSP70 lysine methylation promotes proliferation of cancer cells through activation of Aurora kinase B.

21 January 2018

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SMYD2-dependent HSP90 methylation promotes cancer cell proliferation by regulating the chaperone complex formation

21 January 2018

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Histone lysine methyltransferase SETD8 promotes carcinogenesis by deregulating PCNA expression

21 January 2018

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Analysis of NUP98/NSD1 translocations in adult AML and MDS patients

21 January 2018

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MMSET Is Highly Expressed and Associated with Aggressiveness in Neuroblastoma

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.2217/EPI.15.32

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release_gzbtpavbwjc3bfvxsk2qsws3im

3 September 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/gzbtpavbwjc3bfvxsk2qsws3im

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference