(Q38475385)

3 September 2017

title

Genome-wide DNA methylation study identifies significant epigenomic changes in osteoarthritic cartilage (English)

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3 September 2017

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Matlock A Jeffries

1

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Judith A. James

7

object named as

Judith A James

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3 September 2017

Madison Donica

2

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3 September 2017

Lyle W Baker

3

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3 September 2017

Michael E Stevenson

4

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3 September 2017

Anand C Annan

5

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3 September 2017

Mary Beth Humphrey

6

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3 September 2017

Amr H Sawalha

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3 September 2017

language of work or name

English

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publication date

1 October 2014

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3 September 2017

published in

Arthritis & Rheumatology

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3 September 2017

volume

66

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3 September 2017

issue

10

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3 September 2017

page(s)

2804-2815

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Pathogenesis and management of pain in osteoarthritis.

3 September 2017

cites work

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Genome-wide DNA methylation study suggests epigenetic accessibility and transcriptional poising of interferon-regulated genes in naïve CD4+ T cells from lupus patients

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Identification of novel markers in rheumatoid arthritis through integrated analysis of DNA methylation and microRNA expression

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Epigenetics in rheumatoid arthritis: a primer for rheumatologists

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Association between the abnormal expression of matrix-degrading enzymes by human osteoarthritic chondrocytes and demethylation of specific CpG sites in the promoter regions.

21 January 2018

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Epigenetic regulation of leptin affects MMP-13 expression in osteoarthritic chondrocytes: possible molecular target for osteoarthritis therapeutic intervention

21 January 2018

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Genome-wide DNA methylation analysis of articular chondrocytes reveals a cluster of osteoarthritic patients

21 January 2018

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Quantitative DNA methylation analysis based on four-dye trace data from direct sequencing of PCR amplificates

21 January 2018

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Dlx5 specifically regulates Runx2 type II expression by binding to homeodomain-response elements in the Runx2 distal promoter

21 January 2018

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A fibrillar collagen gene, Col11a1, is essential for skeletal morphogenesis

21 January 2018

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Histopathology grading systems for characterisation of human knee osteoarthritis--reproducibility, variability, reliability, correlation, and validity.

21 January 2018

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Loss of methylation in CpG sites in the NF-κB enhancer elements of inducible nitric oxide synthase is responsible for gene induction in human articular chondrocytes.

21 January 2018

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Characterization of proADAMTS5 processing by proprotein convertases.

21 January 2018

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Inhibition of furin-like enzymes blocks interleukin-1alpha/oncostatin M-stimulated cartilage degradation

21 January 2018

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Evidence that furin is an authentic transforming growth factor-beta1-converting enzyme

21 January 2018

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Inhibition of TGF-β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis

21 January 2018

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Genome-wide expression profiling reveals new candidate genes associated with osteoarthritis.

21 January 2018

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C/EBPβ and RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2α as the inducer in chondrocytes

21 January 2018

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Combination of MEK-ERK inhibitor and hyaluronic acid has a synergistic effect on anti-hypertrophic and pro-chondrogenic activities in osteoarthritis treatment.

21 January 2018

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Modulating hedgehog signaling can attenuate the severity of osteoarthritis.

21 January 2018

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The role of human HtrA1 in arthritic disease

21 January 2018

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Human HtrA, an evolutionarily conserved serine protease identified as a differentially expressed gene product in osteoarthritic cartilage

21 January 2018

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Identification of a novel HtrA1-susceptible cleavage site in human aggrecan: evidence for the involvement of HtrA1 in aggrecan proteolysis in vivo

21 January 2018

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NFATc1 and NFATc2 repress spontaneous osteoarthritis

21 January 2018

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Autosomal dominant and recessive osteochondrodysplasias associated with the COL11A2 locus

21 January 2018

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Genetic associations in peripheral joint osteoarthritis and spinal degenerative disease: a systematic review

21 January 2018

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In vitro cartilage formation by human adult stem cells from bone marrow stroma defines the sequence of cellular and molecular events during chondrogenesis

21 January 2018

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TGF-beta/Smad3 signals repress chondrocyte hypertrophic differentiation and are required for maintaining articular cartilage

21 January 2018

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15-deoxy-Δ(12,14) -prostaglandin-J2 and ciglitazone inhibit TNF-α-induced matrix metalloproteinase 13 production via the antagonism of NF-κB activation in human synovial fibroblasts

21 January 2018

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The identification of differentially expressed microRNA in osteoarthritic tissue that modulate the production of TNF-alpha and MMP13.

21 January 2018

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Regulation of the IGFBP-5 and MMP-13 genes by the microRNAs miR-140 and miR-27a in human osteoarthritic chondrocytes

21 January 2018

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The role of ERG (ets related gene) in cartilage development

21 January 2018

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The effects of specific medical conditions on the functional limitations of elders in the Framingham Study

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/ART.38762

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3 September 2017

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