(Q38475630)

3 September 2017

1 reference

title

"Pruning of biomolecules and natural products (PBNP)": an innovative paradigm in drug discovery (English)

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3 September 2017

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1 reference

Surendar Reddy Bathula

1

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3 September 2017

Srirama Murthy Akondi

2

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3 September 2017

Prathama S Mainkar

3

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3 September 2017

Srivari Chandrasekhar

4

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3 September 2017

13 May 2015

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Organic and Biomolecular Chemistry

3 September 2017

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3 September 2017

13

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3 September 2017

23

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3 September 2017

6432-6448

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Structural mechanism for statin inhibition of HMG-CoA reductase

3 September 2017

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Olanzapine: a critical review of recent literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Chronic Myeloid Leukemia — Advances in Biology and New Approaches to Treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Targeted cancer therapies in the twenty-first century: lessons from imatinib

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

FK-506, a novel immunosuppressant isolated from a Streptomyces. I. Fermentation, isolation, and physico-chemical and biological characteristics

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Sourcing a chemical succession for cyclosporin from parasites and human pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

From Norway to Novartis: cyclosporin from Tolypocladium inflatum in an open access bioprospecting regime

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Liver transplantation with use of cyclosporin a and prednisone

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Promotion of microtubule assembly in vitro by taxol

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Plant antitumor agents. VI. The isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Plant Antitumor Agents. I. The Isolation and Structure of Camptothecin, a Novel Alkaloidal Leukemia and Tumor Inhibitor from Camptotheca acuminata1,2

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Molecular Target-Guided Tumor Therapy with Natural Products Derived from Traditional Chinese Medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Galantamine: a review of its use in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Antitumor compounds from tunicates

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Meta-omic characterization of the marine invertebrate microbial consortium that produces the chemotherapeutic natural product ET-743

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Bioactive compounds from aquatic and terrestrial sources

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Natural products from Cephalotaxus sp.: chemical diversity and synthetic aspects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

TOTAL SYNTHESIS OF d,l-LONGIFOLENE

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Target-oriented and diversity-oriented organic synthesis in drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

From protein domains to drug candidates-natural products as guiding principles in the design and synthesis of compound libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Biology-oriented synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Natural product hybrids as new leads for drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Hybrid systems through natural product leads: an approach towards new molecular entities

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Advances in computational methods to predict the biological activity of compounds.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Bioisosterism: A Rational Approach in Drug Design

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Fragment-based approaches in drug discovery and chemical biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Fragment-based lead discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Combinatorial target-guided ligand assembly: identification of potent subtype-selective c-Src inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

The Total Synthesis of (+)-Migrastatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Discovery of potent cell migration inhibitors through total synthesis: lessons from structure-activity studies of (+)-migrastatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

The migrastatin family: discovery of potent cell migration inhibitors by chemical synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Synthetic analogues of migrastatin that inhibit mammary tumor metastasis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Über den jetzigen Stand der Chemotherapie

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Pharmacophore modeling and applications in drug discovery: challenges and recent advances

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

PENTAZOCINE. STRONG ANALGESICS AND ANALGESIC ANTAGONISTS IN THE BENZOMORPHAN SERIES.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

21 January 2018

Cyclazocine revisited

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Meperidine: a critical review

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Synopsis of some recent tactical application of bioisosteres in drug design

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Neuropeptide Y-related peptides and their receptors--are the receptors potential therapeutic drug targets?

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Broad spectrum antibiotic activity of the skin-PYY.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Relaxin: new functions for an old peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Cardiovascular effects of relaxin: from basic science to clinical therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Relaxin: a disulfide homolog of insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

The relaxin peptide family--structure, function and clinical applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

The minimal active structure of human relaxin-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Truncated Orexin Peptides: Structure-Activity Relationship Studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

The disulphide bonds of insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Newer insulin analogs: advances in basal insulin replacement

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

A review of modern insulin analogue pharmacokinetic and pharmacodynamic profiles in type 2 diabetes: improvements and limitations

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Insulin structure and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Replacement of the CysA7-CysB7 disulfide bond with a 1,2,3-triazole linker causes unfolding in insulin glargine

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Implications for the active form of human insulin based on the structural convergence of highly active hormone analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Insulin analogs with B24 or B25 phenylalanine replaced by biphenylalanine

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Insulin analogues with modifications at position B26. Divergence of binding affinity and biological activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Opportunities in somatostatin research: biological, chemical and therapeutic aspects

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Improvement of drug-like properties of peptides: the somatostatin paradigm

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

SMS 201–995: A very potent and selective octapeptide analogue of somatostatin with prolonged action

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Synthetic therapeutic peptides: science and market

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Automated polysaccharide synthesis: assembly of a 30mer mannoside.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Engineering nanoassemblies of polysaccharides

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Inhibition of oxidative stress by low-molecular-weight polysaccharides with various functional groups in skin fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Parenteral anticoagulants: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Chitin and chitosan: Properties and applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

The versatile biopolymer chitosan: potential sources, evaluation of extraction methods and applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Chitosan derivatives with antimicrobial, antitumour and antioxidant activities--a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Low molecular weight and oligomeric chitosans and their bioactivities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Vaccine adjuvants: current state and future trends

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Synthesis of a malaria candidate glycosylphosphatidylinositol (GPI) structure: a strategy for fully inositol acylated and phosphorylated GPIs

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Low molecular weight chitosan prevents the progression of low dose streptozotocin-induced slowly progressive diabetes mellitus in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

A comparative study on hypolipidemic activities of high and low molecular weight chitosan in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Design and synthesis of potent Quillaja saponin vaccine adjuvants

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Synthesis of QS-21-xylose: establishment of the immunopotentiating activity of synthetic QS-21 adjuvant with a melanoma vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Synthesis and preclinical evaluation of QS-21 variants leading to simplified vaccine adjuvants and mechanistic probes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Development of a minimal saponin vaccine adjuvant based on QS-21

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Toward an understanding of NKT cell biology: progress and paradoxes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Toll-like receptor agonists and alpha-galactosylceramide synergistically enhance the production of interferon-gamma in murine splenocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Synthesis and evaluation of sphinganine analogues of KRN7000 and OCH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Automated oligosaccharide synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

RNA targeting therapeutics: molecular mechanisms of antisense oligonucleotides as a therapeutic platform

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Mechanisms of alternative pre-messenger RNA splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Identification of tissue-specific microRNAs from mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Origins and Mechanisms of miRNAs and siRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Introduction of a Chimeric Chalcone Synthase Gene into Petunia Results in Reversible Co-Suppression of Homologous Genes in trans

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Cosuppression comes to the animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

RNA as a target of double-stranded RNA-mediated genetic interference in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

RNA-based therapeutics: current progress and future prospects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Nucleic-acid therapeutics: basic principles and recent applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

RNA interference: from basic research to therapeutic applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Next generation sequencing technology: Advances and applications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Sequencing technologies and genome sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

The chemical synthesis of DNA/RNA: our gift to science

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Stereocontrolled solid-phase synthesis of oligonucleoside H-phosphonates by an oxazaphospholidine approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Frontiers of mass spectrometry in nucleic acids analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Natural products as sources of new drugs over the 30 years from 1981 to 2010

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Macrocyclic ketone analogues of halichondrin B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Discovery of fingolimod, the sphingosine 1-phosphate receptor modulator and its application for the therapy of multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Synthesis and immunosuppressive activity of 2-substituted 2-aminopropane-1,3-diols and 2-aminoethanols

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Discovery of dapagliflozin: a potent, selective renal sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor for the treatment of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Endogenous and exogenous cardiac glycosides: their roles in hypertension, salt metabolism, and cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Rostafuroxin: an ouabain-inhibitor counteracting specific forms of hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

A new alkaloid AM-2282 OF Streptomyces origin. Taxonomy, fermentation, isolation and preliminary characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Absolute Configuration of Staurosporine By X-Ray Analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Staurosporine, K-252 and UCN-01: potent but nonspecific inhibitors of protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Discovery of 3-(1H-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]pyrrole-2,5-dione (AEB071), a potent and selective inhibitor of protein kinase C isotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Synthesis of a ring-expanded bryostatin analogue

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Pladienolides, new substances from culture of Streptomyces platensis Mer-11107. I. Taxonomy, fermentation, isolation and screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Recent developments in the synthesis of prostaglandins and analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Migrastatin analogues target fascin to block tumour metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Confirmation of the Structures of Synthetic Derivatives of Migrastatin in the Light of Recently Disclosed Crystallographically Based Claims.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Analysis of the phorbol ester pharmacophore on protein kinase C as a guide to the rational design of new classes of analogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Modeling of the bryostatins to the phorbol ester pharmacophore on protein kinase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

The design, computer modeling, solution structure, and biological evaluation of synthetic analogs of bryostatin 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Golgi-modifying properties of macfarlandin E and the synthesis and evaluation of its 2,7-dioxabicyclo[3.2.1]octan-3-one core

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Anguinomycins and derivatives: total syntheses, modeling, and biological evaluation of the inhibition of nucleocytoplasmic transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Controlling protein transport by small molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Isolation and structure of bryostatin 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

A potent cyclic hexapeptide analogue of somatostatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5OB00403A

Fungal metabolites. Part 11. A potent immunosuppressive activity found in Isaria sinclairii metabolite

21 January 2018

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.47.208

Studies on the differentiation inducers of myeloid leukemic cells. III. Spicamycin, a new inducer of differentiation of HL-60 human promyelocytic leukemia cells

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.36.934

Identifiers

DOI

10.1039/C5OB00403A

1 reference

3 September 2017

1 reference