(Q38476087)

3 September 2017

Hemin, an iron-binding porphyrin, inhibits HIF-1α induction through its binding with heat shock protein 90. (English)

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3 September 2017

5

Aree Moon

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3 September 2017

Jung Min Lee

1

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3 September 2017

Woo Hyung Lee

2

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3 September 2017

Hee Yeon Kay

3

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3 September 2017

Eun-sook Kim

4

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3 September 2017

Sang Geon Kim

6

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3 September 2017

language of work or name

English

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publication date

30 May 2011

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International Journal of Cancer

3 September 2017

12

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based on heuristic

inferred from page(s)

published in

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3 September 2017

130

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3 September 2017

3

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3 September 2017

716-727

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Heme as key regulator of major mammalian cellular functions: molecular, cellular, and pharmacological aspects.

3 September 2017

1 reference

Hemin inhibits cyclooxygenase-2 expression through nuclear factor-kappa B activation and ornithine decarboxylase expression in 12-O-tetradecanoylphorbol-13-acetate-treated mouse skin

21 January 2018

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Protective effects of hemin and tetrakis(4-benzoic acid)porphyrin on bacterial mutagenesis and mouse skin carcinogenesis induced by 7, 12-dimethylbenz[a]anthracene.

21 January 2018

1 reference

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

21 January 2018

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Regulation of angiogenesis by hypoxia: role of the HIF system

21 January 2018

1 reference

Harnessing the hypoxia-inducible factor in cancer and ischemic disease

21 January 2018

1 reference

Cancer cell metabolism: Warburg and beyond

21 January 2018

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Reversing hypoxic cell chemoresistance in vitro using genetic and small molecule approaches targeting hypoxia inducible factor-1.

21 January 2018

1 reference

Targeting HSP90 for cancer therapy

21 January 2018

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Heat shock protein 90 as a drug target: some like it hot.

21 January 2018

1 reference

Hypoxia-induced activation of HIF-1: role of HIF-1alpha-Hsp90 interaction

21 January 2018

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Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1 alpha-degradative pathway

21 January 2018

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RACK1 vs. HSP90: competition for HIF-1 alpha degradation vs. stabilization

21 January 2018

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Structural basis for depletion of heat shock protein 90 client proteins by deguelin.

21 January 2018

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Reduction of hypoxia-induced transcription through the repression of hypoxia-inducible factor-1alpha/aryl hydrocarbon receptor nuclear translocator DNA binding by the 90-kDa heat-shock protein inhibitor radicicol

21 January 2018

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Role of Galpha12 and Galpha13 as novel switches for the activity of Nrf2, a key antioxidative transcription factor

21 January 2018

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A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development

21 January 2018

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Green tea extract and (-)-epigallocatechin-3-gallate inhibit hypoxia- and serum-induced HIF-1alpha protein accumulation and VEGF expression in human cervical carcinoma and hepatoma cells.

21 January 2018

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Human rhabdomyosarcoma cells retain insulin-regulated glucose transport activity through glucose transporter 1.

21 January 2018

1 reference

Hypoxia-inducible factor-1alpha and hypoxia-inducible factor-2alpha are expressed in kaposi sarcoma and modulated by insulin-like growth factor-I.

21 January 2018

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Efficacy of sauchinone as a novel AMPK-activating lignan for preventing iron-induced oxidative stress and liver injury.

21 January 2018

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Antiangiogenic effect of deguelin on choroidal neovascularization

21 January 2018

1 reference

Bovine type I collagen inhibits Raw264.7 cell proliferation through phosphoinositide 3-kinase- and mitogen-activated protein kinase-dependent down-regulation of cyclins D1, A and B1.

21 January 2018

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Metastasis-associated protein 1 enhances stability of hypoxia-inducible factor-1alpha protein by recruiting histone deacetylase 1.

21 January 2018

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Activating transcription factor 2 mediates matrix metalloproteinase-2 transcriptional activation induced by p38 in breast epithelial cells

21 January 2018

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Insulin-induced activation of hypoxia-inducible factor-1 requires generation of reactive oxygen species by NADPH oxidase

21 January 2018

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Identification of alternative spliced variants of human hypoxia-inducible factor-1alpha

21 January 2018

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Angiogenesis: an organizing principle for drug discovery?

21 January 2018

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Redox regulation of the hypoxia-inducible factor

21 January 2018

1 reference

Reactive oxygen species and cellular oxygen sensing

21 January 2018

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Inhibition of Hsp90: a new strategy for inhibiting protein kinases

21 January 2018

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HIF-dependent antitumorigenic effect of antioxidants in vivo

21 January 2018

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DNA and mRNA elements with complementary responses to hemin, antioxidant inducers, and iron control ferritin-L expression

21 January 2018

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Free heme toxicity and its detoxification systems in human

21 January 2018

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Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway

21 January 2018

1 reference

HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression

21 January 2018

1 reference

AMP-activated protein kinase activity is critical for hypoxia-inducible factor-1 transcriptional activity and its target gene expression under hypoxic conditions in DU145 cells

21 January 2018

1 reference

Reactive oxygen species stabilize hypoxia-inducible factor-1 alpha protein and stimulate transcriptional activity via AMP-activated protein kinase in DU145 human prostate cancer cells

21 January 2018

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AMPK activation inhibits the expression of HIF-1alpha induced by insulin and IGF-1.

21 January 2018

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Glycogen synthase kinase 3 phosphorylates hypoxia-inducible factor 1alpha and mediates its destabilization in a VHL-independent manner

21 January 2018

1 reference

Protein kinase C-delta regulates the stability of hypoxia-inducible factor-1 alpha under hypoxia

21 January 2018

1 reference

c-Jun NH2-terminal kinase activation contributes to hypoxia-inducible factor 1alpha-dependent P-glycoprotein expression in hypoxia

21 January 2018

1 reference

Pharmacokinetics of intravenously administered haem arginate

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/IJC.26075

1 reference

release_7k3yf55g6rcoth2n6s72smjt6i

3 September 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/7k3yf55g6rcoth2n6s72smjt6i

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference