(Q38555175)

4 September 2017

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title

Role of mitochondrial dysfunction and dysregulation of Ca(2+) homeostasis in insulin insensitivity of mammalian cells (English)

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4 September 2017

Chih-Hao Wang

1

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4 September 2017

Ting-Fen Tsai

series ordinal

2

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4 September 2017

Yau-Huei Wei

series ordinal

3

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4 September 2017

language of work or name

English

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publication date

27 July 2015

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Annals of the New York Academy of Sciences

4 September 2017

published in

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4 September 2017

volume

1350

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4 September 2017

page(s)

66-76

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Diabetes Treatment — Bridging the Divide

4 September 2017

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Liver ATP synthesis is lower and relates to insulin sensitivity in patients with type 2 diabetes.

21 January 2018

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Physical activity is the key determinant of skeletal muscle mitochondrial function in type 2 diabetes.

21 January 2018

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Time course of high-fat diet-induced reductions in adipose tissue mitochondrial proteins: potential mechanisms and the relationship to glucose intolerance

21 January 2018

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Hypermethylation of Cox5a promoter is associated with mitochondrial dysfunction in skeletal muscle of high fat diet-induced insulin resistant rats

21 January 2018

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Resveratrol attenuates high-fat diet-induced insulin resistance by influencing skeletal muscle lipid transport and subsarcolemmal mitochondrial β-oxidation

21 January 2018

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Adipose mitochondrial biogenesis is suppressed in db/db and high-fat diet-fed mice and improved by rosiglitazone.

21 January 2018

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Impaired mitochondrial dynamics and bioenergetics in diabetic skeletal muscle

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Molecular and metabolic evidence for mitochondrial defects associated with beta-cell dysfunction in a mouse model of type 2 diabetes

21 January 2018

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Mitochondrial dysfunction leads to impairment of insulin sensitivity and adiponectin secretion in adipocytes

21 January 2018

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Cisd2 deficiency drives premature aging and causes mitochondria-mediated defects in mice

21 January 2018

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The versatility of mitochondrial calcium signals: from stimulation of cell metabolism to induction of cell death

21 January 2018

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The mitochondrial calcium uniporter complex: molecular components, structure and physiopathological implications

21 January 2018

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The mitochondrial Ca(2+) uniporter complex

21 January 2018

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Molecular identity and functional properties of the mitochondrial Na+/Ca2+ exchanger

21 January 2018

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The mitochondrial permeability transition: a current perspective on its identity and role in ischaemia/reperfusion injury.

21 January 2018

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Regulation of ATP production by mitochondrial Ca(2+).

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21 January 2018

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Active mitochondria surrounding the pancreatic acinar granule region prevent spreading of inositol trisphosphate-evoked local cytosolic Ca(2+) signals.

21 January 2018

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Enhancing mitochondrial calcium buffering capacity reduces aggregation of misfolded SOD1 and motor neuron cell death without extending survival in mouse models of inherited amyotrophic lateral sclerosis

21 January 2018

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Activation of calcium/calmodulin-dependent protein kinase II in obesity mediates suppression of hepatic insulin signaling.

21 January 2018

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Serum calcium is positively correlated with fasting plasma glucose and insulin resistance, independent of parathyroid hormone, in male patients with type 2 diabetes mellitus.

21 January 2018

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Improvement of insulin sensitivity by chelation of intracellular Ca(2+) in high-fat-fed rats.

21 January 2018

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Inflammation and insulin resistance induced by trans-10, cis-12 conjugated linoleic acid depend on intracellular calcium levels in primary cultures of human adipocytes

21 January 2018

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An inositol 1,4,5-triphosphate (IP3)-IP3 receptor pathway is required for insulin-stimulated glucose transporter 4 translocation and glucose uptake in cardiomyocytes

21 January 2018

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The role of Ca2+ influx for insulin-mediated glucose uptake in skeletal muscle.

21 January 2018

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Regulation of insulin secretion and GLUT4 trafficking by the calcium sensor synaptotagmin VII.

21 January 2018

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Glucose transporter recycling in response to insulin is facilitated by myosin Myo1c

21 January 2018

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Activation of RalA is required for insulin-stimulated Glut4 trafficking to the plasma membrane via the exocyst and the motor protein Myo1c

21 January 2018

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CaMKII-mediated phosphorylation of the myosin motor Myo1c is required for insulin-stimulated GLUT4 translocation in adipocytes

21 January 2018

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FAM3A activates PI3K p110α/Akt signaling to ameliorate hepatic gluconeogenesis and lipogenesis.

21 January 2018

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Mitochondrial function in normal and diabetic beta-cells

21 January 2018

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Mitochondria and endoplasmic reticulum: mitochondria-endoplasmic reticulum interplay in type 2 diabetes pathophysiology

21 January 2018

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Mitochondrial Ca2+ uptake 1 (MICU1) and mitochondrial ca2+ uniporter (MCU) contribute to metabolism-secretion coupling in clonal pancreatic β-cells

21 January 2018

1 reference

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Essential role of mitochondrial Ca2+ uniporter in the generation of mitochondrial pH gradient and metabolism-secretion coupling in insulin-releasing cells

21 January 2018

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High extracellular calcium attenuates adipogenesis in 3T3-L1 preadipocytes.

21 January 2018

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Prostaglandin F2alpha inhibits adipocyte differentiation via a G alpha q-calcium-calcineurin-dependent signaling pathway

21 January 2018

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Activation of transient receptor potential vanilloid type-1 channel prevents adipogenesis and obesity

21 January 2018

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Calcineurin mediates the calcium-dependent inhibition of adipocyte differentiation in 3T3-L1 cells

21 January 2018

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The Ca2+/calmodulin-dependent protein kinase kinase, CaMKK2, inhibits preadipocyte differentiation.

21 January 2018

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Calreticulin inhibits commitment to adipocyte differentiation

21 January 2018

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Adipokines as regulators of muscle metabolism and insulin sensitivity

21 January 2018

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https://api.crossref.org/works/10.1111%2FNYAS.12838

The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

21 January 2018

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https://api.crossref.org/works/10.1111%2FNYAS.12838

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

21 January 2018

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Adiponectin and AdipoR1 regulate PGC-1alpha and mitochondria by Ca(2+) and AMPK/SIRT1.

21 January 2018

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Endoplasmic reticulum stress markers are associated with obesity in nondiabetic subjects

21 January 2018

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https://api.crossref.org/works/10.1111%2FNYAS.12838

Increase in endoplasmic reticulum stress-related proteins and genes in adipose tissue of obese, insulin-resistant individuals

21 January 2018

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Protective effect of liraglutide against ER stress in the liver of high-fat diet-induced insulin-resistant rats.

21 January 2018

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https://api.crossref.org/works/10.1111%2FNYAS.12838

Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes

21 January 2018

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https://api.crossref.org/works/10.1111%2FNYAS.12838

Restoration of autophagy alleviates hepatic ER stress and impaired insulin signalling transduction in high fructose-fed male mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNYAS.12838

Role of hepatocyte S6K1 in palmitic acid-induced endoplasmic reticulum stress, lipotoxicity, insulin resistance and in oleic acid-induced protection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNYAS.12838

Administration of progranulin (PGRN) triggers ER stress and impairs insulin sensitivity via PERK-eIF2α-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNYAS.12838

Involvement of endoplasmic reticulum stress in insulin resistance and diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNYAS.12838

Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNYAS.12838

Calcium signaling around Mitochondria Associated Membranes (MAMs).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNYAS.12838

Structural and functional features and significance of the physical linkage between ER and mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNYAS.12838

Mitochondria-associated membranes (MAMs) as hotspot Ca(2+) signaling units

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNYAS.12838

Mitochondria and endoplasmic reticulum: the lethal interorganelle cross-talk

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNYAS.12838

Interaction between mitochondria and the endoplasmic reticulum: implications for the pathogenesis of type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNYAS.12838

Modulation of the endoplasmic reticulum-mitochondria interface in Alzheimer's disease and related models

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNYAS.12838

FACL4, a new gene encoding long-chain acyl-CoA synthetase 4, is deleted in a family with Alport syndrome, elliptocytosis, and mental retardation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNYAS.12838

Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNYAS.12838

Chronic enrichment of hepatic endoplasmic reticulum-mitochondria contact leads to mitochondrial dysfunction in obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNYAS.12838

Mitochondria-associated endoplasmic reticulum membrane (MAM) integrity is required for insulin signaling and is implicated in hepatic insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNYAS.12838

21 January 2018

Identifiers

DOI

10.1111/NYAS.12838

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4 September 2017

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