(Q38556654)

4 September 2017

1 reference

title

Maintaining epithelial stemness with p63. (English)

1 reference

4 September 2017

4

Francesca Bernassola

1 reference

4 September 2017

Gerry Melino

1

1 reference

PubMed ID

26221054

4 September 2017

Elisa Maria Memmi

series ordinal

2

1 reference

PubMed ID

26221054

4 September 2017

Pier Giuseppe Pelicci

series ordinal

3

1 reference

4 September 2017

28 July 2015

1 reference

4 September 2017

1 reference

4 September 2017

8

1 reference

4 September 2017

re9

1 reference

4 September 2017

387

1 reference

p73: Friend or foe in tumorigenesis

4 September 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

Structural evolution of C-terminal domains in the p53 family

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

p63 is a suppressor of tumorigenesis and metastasis interacting with mutant p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

The p53 family: guardians of maternal reproduction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

p63 in epithelial survival, germ cell surveillance, and neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

p63 regulates an adhesion programme and cell survival in epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

Perp is a p63-regulated gene essential for epithelial integrity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

Mutant p53 drives invasion by promoting integrin recycling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

p63 steps into the limelight: crucial roles in the suppression of tumorigenesis and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

TAp63 induces senescence and suppresses tumorigenesis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

p63 protects the female germ line during meiotic arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

Differential recognition of response elements determines target gene specificity for p53 and p63

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

p53/p63/p73 isoforms: an orchestra of isoforms to harmonise cell differentiation and response to stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

TP53 family members and human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

The unique NH2-terminally deleted (DeltaN) residues, the PXXP motif, and the PPXY motif are required for the transcriptional activity of the DeltaN variant of p63.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

New p63 targets in keratinocytes identified by a genome-wide approach.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

Genome-wide profiling of p63 DNA-binding sites identifies an element that regulates gene expression during limb development in the 7q21 SHFM1 locus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

DeltaNp63 regulates thymic development through enhanced expression of FgfR2 and Jag2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

Differential expression of p63 isoforms in normal tissues and neoplastic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

p63 Is essential for the proliferative potential of stem cells in stratified epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

Self-renewal and multilineage differentiation in vitro from murine prostate stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

ΔNp63 promotes stem cell activity in mammary gland development and basal-like breast cancer by enhancing Fzd7 expression and Wnt signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

Asymmetric and symmetric stem-cell divisions in development and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

Differential roles of p63 isoforms in epidermal development: selective genetic complementation in p63 null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

p63 is a p53 homologue required for limb and epidermal morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

p63, a story of mice and men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

ΔNp63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

p63 is the molecular switch for initiation of an epithelial stratification program

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

Increased p63 phosphorylation marks early transition of epidermal stem cells to progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

p63 regulates olfactory stem cell self-renewal and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

p63, a p53 homologue, is a selective nuclear marker of myoepithelial cells of the human breast

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

Reciprocal intraepithelial interactions between TP63 and hedgehog signaling regulate quiescence and activation of progenitor elaboration by mammary stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

ΔNp63α promotes cellular quiescence via induction and activation of Notch3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

p63 is a prosurvival factor in the adult mammary gland during post-lactational involution, affecting PI-MECs and ErbB2 tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

p63 is a prostate basal cell marker and is required for prostate development

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

p63 regulates commitment to the prostate cell lineage

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

p63-expressing cells are the stem cells of developing prostate, bladder, and colorectal epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

Sca-1 expression identifies stem cells in the proximal region of prostatic ducts with high capacity to reconstitute prostatic tissue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

Characterization of adult prostatic progenitor/stem cells exhibiting self-renewal and multilineage differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

p63 heterozygous mutant mice are not prone to spontaneous or chemically induced tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

Functional regulation of p73 and p63: development and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

TAp63 and DeltaNp63 in cancer and epidermal development

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

The p63/p73 network mediates chemosensitivity to cisplatin in a biologically defined subset of primary breast cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

p63 expression in normal, hyperplastic and malignant breast tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

Overexpression of ΔNp63α induces a stem cell phenotype in MCF7 breast carcinoma cell line through the Notch pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

p63 Sustains self-renewal of mammary cancer stem cells through regulation of Sonic Hedgehog signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

ΔNp63α-mediated activation of bone morphogenetic protein signaling governs stem cell activity and plasticity in normal and malignant mammary epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

ΔNP63α transcriptionally activates chemokine receptor 4 (CXCR4) expression to regulate breast cancer stem cell activity and chemotaxis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

Lin-Sca-1+CD49fhigh stem/progenitors are tumor-initiating cells in the Pten-null prostate cancer model

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

p53 suppresses the self-renewal of adult neural stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

The tumor suppressor p53 regulates polarity of self-renewing divisions in mammary stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

Cellular Senescence:Ex Vivop53-Dependent Asymmetric Cell Kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

Asymmetric cell divisions promote stratification and differentiation of mammalian skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

Generation of a functional mammary gland from a single stem cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

Wnt signaling in stem and cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

dishevelled and armadillo act in the wingless signalling pathway in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

Role of Notch signaling in cell-fate determination of human mammary stem/progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

Notch signaling regulates mammary stem cell function and luminal cell-fate commitment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

Role of p63 and the Notch pathway in cochlea development and sensorineural deafness

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

Antagonistic roles of Notch and p63 in controlling mammary epithelial cell fates

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

Notch signaling represses p63 expression in the developing surface ectoderm

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

Notch signaling mediates p63-induced quiescence: a new facet of p63/Notch crosstalk

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

Loss of a quiescent niche but not follicle stem cells in the absence of bone morphogenetic protein signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

p51/p63 Controls subunit alpha3 of the major epidermis integrin anchoring the stem cells to the niche

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

Identification of new p63 targets in human keratinocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

DeltaNp63 isoforms regulate CD44 and keratins 4, 6, 14 and 19 in squamous cell carcinoma of head and neck

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

Cbx4 regulates the proliferation of thymic epithelial cells and thymus function

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

p63 regulates Satb1 to control tissue-specific chromatin remodeling during development of the epidermis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

p63 and p73 are required for p53-dependent apoptosis in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.AAA1033

10.1126/SCISIGNAL.AAA1033

21 January 2018

Identifiers

DOI

1 reference

4 September 2017

1 reference

PubMed ID

26221054