(Q38563910)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26259962%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

review article

1 reference

title

Cancer-associated fibroblasts as target and tool in cancer therapeutics and diagnostics (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26259962%20AND%20SRC:MED&resulttype=core&format=json

cancer-associated fibroblast

22 February 2020

main subject

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26259962%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

5

Olivier De Wever

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26259962%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

4

Marc Bracke

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26259962%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

2

Laurine Verset

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26259962%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

3

Pieter Demetter

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26259962%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

publication date

11 August 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26259962%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26259962%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

volume

467

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26259962%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26259962%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

page(s)

367-382

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26259962%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/s00428-015-1818-4

22 February 2020

exact match

0 references

cites work

Modulation of the tumor microenvironment for cancer treatment: a biomaterials approach

1 reference

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Stromal disrupting effects of nab-paclitaxel in pancreatic cancer

21 January 2018

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Multiplexed ion beam imaging of human breast tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Stromal expression of fibroblast activation protein/seprase, a cell membrane serine proteinase and gelatinase, is associated with longer survival in patients with invasive ductal carcinoma of breast

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Boron neutron capture therapy of cancer: current status and future prospects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Cancer-associated fibroblasts, a parameter of the tumor microenvironment, overcomes carcinoma-associated parameters in the prognosis of patients with mobile tongue cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Small functional groups for controlled differentiation of hydrogel-encapsulated human mesenchymal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Bioengineered implantable scaffolds as a tool to study stromal-derived factors in metastatic cancer models

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Microfluidic organs-on-chips.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Cell specific ingrowth hydrogels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Targeting carcinoma-associated fibroblasts within the tumor stroma with a fibroblast activation protein-activated prodrug

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Semi-mechanistic modelling of the tumour growth inhibitory effects of LY2157299, a new type I receptor TGF-beta kinase antagonist, in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Stromal gene expression defines poor-prognosis subtypes in colorectal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Stromagenesis during tumorigenesis: characterization of tumor-associated fibroblasts and stroma-derived 3D matrices

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Fibroblast activation protein and its relationship to clinical outcome in pancreatic adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Tumor-environment biomimetics delay peritoneal metastasis formation by deceiving and redirecting disseminated cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Stromal myofibroblasts are drivers of invasive cancer growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Single cell and spheroid collagen type I invasion assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Carcinoma-associated fibroblasts provide operational flexibility in metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Prognostic significance of the tumor-stroma ratio: validation study in node-negative premenopausal breast cancer patients from the EORTC perioperative chemotherapy (POP) trial (10854).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Differential impact of TGF-beta and EGF on fibroblast differentiation and invasion reciprocally promotes colon cancer cell invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

α-Smooth muscle actin-positive myofibroblasts, in association with epithelial-mesenchymal transition and lymphogenesis, is a critical prognostic parameter in patients with oral tongue squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Chemotherapeutic drug delivery to cancer cells using a combination of folate targeting and tumor microenvironment-sensitive polypeptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Cremophor EL: the drawbacks and advantages of vehicle selection for drug formulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

The prognostic significance of cancer-associated fibroblasts in esophageal squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Biofunctionalization of electrospun PCL-based scaffolds with perlecan domain IV peptide to create a 3-D pharmacokinetic cancer model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Microfabricated electrospun collagen membranes for 3-D cancer models and drug screening applications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Cancer-associated fibroblast and M2 macrophage markers together predict outcome in colorectal cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Functional heterogeneity of cancer-associated fibroblasts from human colon tumors shows specific prognostic gene expression signature

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Three-dimensional cancer models mimic cell-matrix interactions in the tumour microenvironment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

BIBF 1120: triple angiokinase inhibitor with sustained receptor blockade and good antitumor efficacy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Recent developments in myofibroblast biology: paradigms for connective tissue remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

3D printing of biomimetic microstructures for cancer cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Can tissue engineering concepts advance tumor biology research?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Stromal contribution to the colorectal cancer transcriptome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Prognostic impact of cancer-associated stromal cells in patients with stage I lung adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Application of high amplitude alternating magnetic fields for heat induction of nanoparticles localized in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Insulin-like growth factor-1 attenuates cisplatin-induced gammaH2AX formation and DNA double-strand breaks repair pathway in non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Significance of stromal desmoplasia and myofibroblast appearance at the invasive front in squamous cell carcinoma of the oral cavity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Cutaneous keratoacanthomas/squamous cell carcinomas associated with neutralization of transforming growth factor β by the monoclonal antibody fresolimumab (GC1008).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Dual role of macrophages in tumor growth and angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Hyaluronic acid-paclitaxel conjugate micelles: synthesis, characterization, and antitumor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Implantable microenvironments to attract hematopoietic stem/cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Capture and printing of fixed stromal cell membranes for bioactive display on PDMS surfaces

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Clinical implications of fibroblast activation protein-α in non-small cell lung cancer after curative resection: a new predictor for prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Chemotherapy activates cancer-associated fibroblasts to maintain colorectal cancer-initiating cells by IL-17A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Degradable ketal-based block copolymer nanoparticles for anticancer drug delivery: a systematic evaluation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Gene expression classification of colon cancer into molecular subtypes: characterization, validation, and prognostic value

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Phase I study of GC1008 (fresolimumab): a human anti-transforming growth factor-beta (TGFβ) monoclonal antibody in patients with advanced malignant melanoma or renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Prognostic gene-expression signature of carcinoma-associated fibroblasts in non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Quantitative evaluation of vimentin expression in tumour stroma of colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Podoplanin-positive cancer-associated fibroblasts could have prognostic value independent of cancer cell phenotype in stage I lung squamous cell carcinoma: usefulness of combining analysis of both cancer cell phenotype and cancer-associated fibrobla

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Prognostic relevance of cancer-associated fibroblasts in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Nintedanib plus docetaxel as second-line therapy in patients with non-small-cell lung cancer: a network meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Podoplanin expression by cancer-associated fibroblasts predicts poor outcome in invasive ductal breast carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Induction of a tumor-metastasis-receptive microenvironment as an unwanted and underestimated side effect of treatment by chemotherapy or radiotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Efficacy of a tyrosine kinase inhibitor in idiopathic pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Paclitaxel-clusters coated with hyaluronan as selective tumor-targeted nanovectors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

The present and future role of microfluidics in biomedical research.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

A colorectal cancer classification system that associates cellular phenotype and responses to therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Cell-selective encapsulation in hydrogel sheaths via biospecific identification and biochemical cross-linking

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Carcinoma-associated fibroblasts derive from mesothelial cells via mesothelial-to-mesenchymal transition in peritoneal metastasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

21 January 2018

Targeted cancer therapy

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Tissue engineering a surrogate niche for metastatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Podoplanin expression in cancer-associated fibroblasts enhances tumor progression of invasive ductal carcinoma of the pancreas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

α-Smooth muscle actin expression and desmoplastic stromal reaction in pancreatic cancer: results from the CONKO-001 study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Transition to invasion in breast cancer: a microfluidic in vitro model enables examination of spatial and temporal effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Development of sarcomas in mice implanted with mesenchymal stem cells seeded onto bioscaffolds.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Carcinoma-associated fibroblasts are a promising therapeutic target.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Immune targeting of fibroblast activation protein triggers recognition of multipotent bone marrow stromal cells and cachexia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Cancer-associated fibroblasts predict poor outcome and promote periostin-dependent invasion in oesophageal adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Differential regulation of extracellular matrix protein expression in carcinoma-associated fibroblasts by TGF-β1 regulates cancer cell spreading but not adhesion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Translation of the ecological trap concept to glioma therapy: the cancer cell trap concept

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Increased survival in pancreatic cancer with nab-paclitaxel plus gemcitabine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

A multipurpose microfluidic device designed to mimic microenvironment gradients and develop targeted cancer therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

The proportion of tumour cells is an independent predictor for survival in colorectal cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

High intratumoral expression of fibroblast activation protein (FAP) in colon cancer is associated with poorer patient prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Podoplanin expression identified in stromal fibroblasts as a favorable prognostic marker in patients with colorectal carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Role of stromal myofibroblasts in invasive breast cancer: stromal expression of alpha-smooth muscle actin correlates with worse clinical outcome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Functional analysis of single cells identifies a rare subset of circulating tumor cells with malignant traits

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Development of TGF-beta signalling inhibitors for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Podoplanin-positive cancer-associated fibroblasts in the tumor microenvironment induce primary resistance to EGFR-TKIs in lung adenocarcinoma with EGFR mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Tunable self-assembled nanogels composed of well-defined thermoresponsive hyaluronic acid–polymer conjugates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Characterization and Magnetic Heating of Commercial Superparamagnetic Iron Oxide Nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-015-1818-4

Cancer-associated fibroblasts and CD163-positive macrophages in oral squamous cell carcinoma: their clinicopathological and prognostic significance

21 January 2018

1 reference

12 December 2020

Podoplanin expression by cancer associated fibroblasts predicts poor prognosis of lung adenocarcinoma

1 reference

12 December 2020

The carcinoma-stromal ratio of colon carcinoma is an independent factor for survival compared to lymph node status and tumor stage.

1 reference

12 December 2020

Impact of different tumour stroma assessment methods regarding podoplanin expression on clinical outcome in patients with invasive ductal breast carcinoma

1 reference

12 December 2020

Albumin-bound formulation of paclitaxel (Abraxane ABI-007) in the treatment of breast cancer

1 reference

12 December 2020

Role of myofibroblasts at the invasion front

1 reference

12 December 2020

Cancer-associated fibroblasts connect metastasis-promoting communication in colorectal cancer

1 reference

12 December 2020

Pharmacological targeting of the protein synthesis mTOR/4E-BP1 pathway in cancer-associated fibroblasts abrogates pancreatic tumour chemoresistance

1 reference

12 December 2020

Tumor-stroma ratio in the primary tumor is a prognostic factor in early breast cancer patients, especially in triple-negative carcinoma patients

1 reference

12 December 2020

Stromal myofibroblasts predict disease recurrence for colorectal cancer

1 reference

12 December 2020

Myofibroblasts in the stroma of oral squamous cell carcinoma are associated with poor prognosis

1 reference

12 December 2020

Clinical implications of fibroblast activation protein in patients with colon cancer

1 reference

12 December 2020

Stromal features are predictive of disease mortality in oral cancer patients

1 reference

12 December 2020

Impact of neoadjuvant therapy on cancer-associated fibroblasts in rectal cancer

1 reference

12 December 2020

Microenvironment-induced downregulation of miR-193b drives ovarian cancer metastasis.

1 reference

12 December 2020

Immunological effects of the TGFβ-blocking antibody GC1008 in malignant pleural mesothelioma patients

1 reference

12 December 2020

Occurence of stromal myofibroblasts in the invasive ductal breast cancer tissue is an unfavourable prognostic factor.

1 reference

12 December 2020

Use of a novel 3D culture model to elucidate the role of mesothelial cells, fibroblasts and extra-cellular matrices on adhesion and invasion of ovarian cancer cells to the omentum

1 reference

12 December 2020

Presence of podoplanin-positive cancer-associated fibroblasts in surgically resected primary lung adenocarcinoma predicts a shorter progression-free survival period in patients with recurrences who received platinum-based chemotherapy

1 reference

12 December 2020

The role of tyrosine kinases in the pathogenesis of idiopathic pulmonary fibrosis.

1 reference

12 December 2020

Tumor-host histopathologic variables, stromal myofibroblasts and risk score, are significantly associated with recurrent disease in tongue cancer

1 reference

12 December 2020

Podoplanin expressing cancer associated fibroblasts are associated with unfavourable prognosis in adenocarcinoma of the esophagus

1 reference

12 December 2020

Podoplanin expression in cancerous stroma induces lymphangiogenesis and predicts lymphatic spread and patient survival

1 reference

12 December 2020

Update on therapeutic management of idiopathic pulmonary fibrosis

1 reference

12 December 2020

Transforming growth factor-β1 and α-smooth muscle actin in stromal fibroblasts are associated with a poor prognosis in patients with clinical stage I-IIIA nonsmall cell lung cancer after curative resection

1 reference

12 December 2020

The prognostic value of tumour-stroma ratio in triple-negative breast cancer

1 reference

12 December 2020

Tumor engineering: the other face of tissue engineering

1 reference

12 December 2020

Podoplanin-expressing cancer-associated fibroblasts are associated with poor prognosis in invasive breast cancer

1 reference

12 December 2020

The proportion of tumor-stroma as a strong prognosticator for stage II and III colon cancer patients: validation in the VICTOR trial

1 reference

12 December 2020