(Q38582573)

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

21 January 2018

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Alpha-synuclein locus duplication as a cause of familial Parkinson's disease

21 January 2018

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alpha-Synuclein locus triplication causes Parkinson's disease

21 January 2018

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Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

21 January 2018

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The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia

21 January 2018

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Alpha-synuclein p.H50Q, a novel pathogenic mutation for Parkinson's disease.

21 January 2018

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A novel α-synuclein missense mutation in Parkinson disease

21 January 2018

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G51D α-synuclein mutation causes a novel parkinsonian-pyramidal syndrome

21 January 2018

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Neuropathological spectrum of synucleinopathies

21 January 2018

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100 years of Lewy pathology.

21 January 2018

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Accumulation of alpha-synuclein/NACP is a cytopathological feature common to Lewy body disease and multiple system atrophy.

21 January 2018

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Multiple system atrophy: a prototypical synucleinopathy for disease-modifying therapeutic strategies.

21 January 2018

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Alpha-synuclein spreading in Parkinson's disease

21 January 2018

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Staging of brain pathology related to sporadic Parkinson's disease

21 January 2018

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Parkinson's disease: a dual-hit hypothesis

21 January 2018

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Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease

21 January 2018

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Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation

21 January 2018

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Research in motion: the enigma of Parkinson's disease pathology spread

21 January 2018

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Genetic mouse models of Parkinson's disease The state of the art.

21 January 2018

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Differential neuropathological alterations in transgenic mice expressing alpha-synuclein from the platelet-derived growth factor and Thy-1 promoters

21 January 2018

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Lrrk2 and alpha-synuclein are co-regulated in rodent striatum

21 January 2018

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E46K human alpha-synuclein transgenic mice develop Lewy-like and tau pathology associated with age-dependent, detrimental motor impairment

21 January 2018

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A progressive dopaminergic phenotype associated with neurotoxic conversion of α-synuclein in BAC-transgenic rats

21 January 2018

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Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein

21 January 2018

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α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells

21 January 2018

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Transfer of host-derived α synuclein to grafted dopaminergic neurons in rat

21 January 2018

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Alpha-synuclein cell-to-cell transfer and seeding in grafted dopaminergic neurons in vivo

21 January 2018

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Alpha-synuclein transfers from neurons to oligodendrocytes

21 January 2018

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Prion-like acceleration of a synucleinopathy in a transgenic mouse model.

21 January 2018

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Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice

21 January 2018

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Pathological α-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice

21 January 2018

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Prion-like spreading of pathological α-synuclein in brain

21 January 2018

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Induction of CNS α-synuclein pathology by fibrillar and non-amyloidogenic recombinant α-synuclein

21 January 2018

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Pathological alpha-synuclein propagates through neural networks

21 January 2018

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Intrastriatal injection of pre-formed mouse α-synuclein fibrils into rats triggers α-synuclein pathology and bilateral nigrostriatal degeneration

21 January 2018

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α-Synuclein strains cause distinct synucleinopathies after local and systemic administration

21 January 2018

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Transmission of multiple system atrophy prions to transgenic mice

21 January 2018

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Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys.

21 January 2018

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Pharmacological promotion of inclusion formation: a therapeutic approach for Huntington's and Parkinson's diseases

21 January 2018

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Progressive aggregation of alpha-synuclein and selective degeneration of lewy inclusion-bearing neurons in a mouse model of parkinsonism

21 January 2018

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Caudo-rostral brain spreading of α-synuclein through vagal connections

21 January 2018

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Neuron-to-neuron α-synuclein propagation in vivo is independent of neuronal injury

21 January 2018

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Transfer of human α-synuclein from the olfactory bulb to interconnected brain regions in mice

21 January 2018

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Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats

21 January 2018

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Intramuscular injection of α-synuclein induces CNS α-synuclein pathology and a rapid-onset motor phenotype in transgenic mice.

21 January 2018

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Heat-shock protein 70 modulates toxic extracellular α-synuclein oligomers and rescues trans-synaptic toxicity

21 January 2018

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Extracellular vesicle sorting of α-Synuclein is regulated by sumoylation

21 January 2018

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Cell-produced alpha-synuclein is secreted in a calcium-dependent manner by exosomes and impacts neuronal survival

21 January 2018

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Intravesicular localization and exocytosis of alpha-synuclein and its aggregates.

21 January 2018

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Exosomal cell-to-cell transmission of alpha synuclein oligomers.

21 January 2018

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Lysosomal dysfunction increases exosome-mediated alpha-synuclein release and transmission.

21 January 2018

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Exosomes as mediators of neuroinflammation

21 January 2018

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Direct transfer of alpha-synuclein from neuron to astroglia causes inflammatory responses in synucleinopathies

21 January 2018

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Assembly-dependent endocytosis and clearance of extracellular alpha-synuclein.

21 January 2018

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Exogenous α-synuclein fibrils induce Lewy body pathology leading to synaptic dysfunction and neuron death

21 January 2018

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Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases

21 January 2018

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Neuron-to-neuron transmission of α-synuclein fibrils through axonal transport

21 January 2018

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Potential of Cellular and Animal Models Based on a Prion-Like Propagation of α-Synuclein for Assessing Antiparkinson Agents

21 January 2018

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Α-synuclein immunotherapy blocks uptake and templated propagation of misfolded α-synuclein and neurodegeneration

21 January 2018

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