(Q38712431)

8 October 2017

In silico design of novel probes for the atypical opioid receptor MRGPRX2. (English)

1 reference

8 October 2017

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288109%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

author name string

Katherine Lansu

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288109%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Joel Karpiak

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288109%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Jing Liu

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288109%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

John D McCorvy

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288109%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Wesley K Kroeze

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288109%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Tao Che

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288109%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Hiroshi Nagase

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288109%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Frank I Carroll

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288109%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Jian Jin

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288109%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Brian K Shoichet

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288109%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Bryan L Roth

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288109%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

publication date

13 March 2017

1 reference

8 October 2017

Nature Chemical Biology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288109%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

volume

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288109%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288109%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

page(s)

529-536

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288109%20AND%20SRC:MED&resulttype=core&format=json

Docking Screens for Novel Ligands Conferring New Biology

31 May 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

Identifying ligands at orphan GPCRs: current status using structure-based approaches

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

The Emerging Role of Spinal Dynorphin in Chronic Pain: A Therapeutic Perspective

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

Allosteric ligands for the pharmacologically dark receptors GPR68 and GPR65.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

NMR structure and dynamics of the agonist dynorphin peptide bound to the human kappa opioid receptor

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

Identification of a mast-cell-specific receptor crucial for pseudo-allergic drug reactions

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

Discovery of Dinaciclib (SCH 727965): A Potent and Selective Inhibitor of Cyclin-Dependent Kinases

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

Computer-aided discovery of aromatic l-α-amino acids as agonists of the orphan G protein-coupled receptor GPR139.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

Preliminary pharmacological evaluation of enantiomeric morphinans.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

Identification of novel functionally selective κ-opioid receptor scaffolds

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

Neuraxial opioid-induced pruritus: An update

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

The druggable genome: Evaluation of drug targets in clinical trials suggests major shifts in molecular class and indication

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

β-Defensins activate human mast cells via Mas-related gene X2.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

A Mast Cell Degranulation Screening Assay for the Identification of Novel Mast Cell Activating Agents

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

Screening β-arrestin recruitment for the identification of natural ligands for orphan G-protein-coupled receptors

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

A pharmacological organization of G protein-coupled receptors

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

New insights from structural biology into the druggability of G protein-coupled receptors.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

Structure-based ligand discovery for the protein-protein interface of chemokine receptor CXCR4

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

Histamine-releasing and allergenic properties of opioid analgesic drugs: resolving the two

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

Ligand discovery from a dopamine D3 receptor homology model and crystal structure

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

Exploring the neuroimmunopharmacology of opioids: an integrative review of mechanisms of central immune signaling and their implications for opioid analgesia

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

Strategies to discover unexpected targets for drugs active at G protein-coupled receptors

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

Determining the neurotransmitter concentration profile at active synapses

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

Comparative protein structure modeling using MODELLER

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

PROMALS3D: a tool for multiple protein sequence and structure alignments

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

dextro-Morphine attenuates the morphine-produced conditioned place preference via the sigma(1) receptor activation in the rat.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

How many drug targets are there?

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

Identification of MrgX2 as a human G-protein-coupled receptor for proadrenomedullin N-terminal peptides

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

ZINC--a free database of commercially available compounds for virtual screening

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

MrgX2 is a high potency cortistatin receptor expressed in dorsal root ganglion

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

Characterization of novel stem cell factor responsive human mast cell lines LAD 1 and 2 established from a patient with mast cell sarcoma/leukemia; activation following aggregation of FcepsilonRI or FcgammaRI.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

Proenkephalin A gene products activate a new family of sensory neuron--specific GPCRs

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

The pharmacological profile of delta opioid receptor ligands, (+) and (-) TAN-67 on pain modulation

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

Transfecting mammalian cells: optimization of critical parameters affecting calcium-phosphate precipitate formation

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

Localization of immunoreactive dynorphin in neurons cultured from spinal cord and dorsal root ganglia

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

Mast cell/nerve interactions in vitro and in vivo

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

Stereospecific and Nonstereospecific Effects of (+)- and (—)-Morphine: Evidence for a New Class of Receptors?

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

Pharmacology of sinomenine, an anti-rheumatic alkaloid from Sinomenium acutum

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

The Recognition of Identical Ligands by Unrelated Proteins

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

[Recreational usage of dextromethorphan--analysis based on internet users experiences].

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

Rapid context-dependent ligand desolvation in molecular docking

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

Discovery of non-peptidergic MrgX1 and MrgX2 receptor agonists and exploration of an initial SAR using solid-phase synthesis

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

Building alternate protein structures using the elastic network model.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

Activation of opioid mu-receptor by sinomenine in cell and mice

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

The repertoire of G-protein-coupled receptors in fully sequenced genomes

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

Histamine Release during Morphine and Fentanyl Anesthesia

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5391270

GPCRDB: an information system for G protein-coupled receptors

31 August 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.2334

Automated docking with grid-based energy evaluation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.2334

New Class IV Charge Model for Extracting Accurate Partial Charges from Wave Functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.2334

Model for Aqueous Solvation Based on Class IV Atomic Charges and First Solvation Shell Effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.2334

On the Role of the Crystal Environment in Determining Protein Side-chain Conformations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.2334

Immunoglobulin E-independent activation of mast cell is mediated by Mrg receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.2334

7 January 2021

Complanadine A, a selective agonist for the Mas-related G protein-coupled receptor X2

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.2334

7 January 2021

Minocycline prevents dynorphin-induced neurotoxicity during neuropathic pain in rats

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.2334

7 January 2021

Epilepsy in Aging Populations

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.2334

7 January 2021

Identifiers

DOI

10.1038/NCHEMBIO.2334

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288109%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

31 May 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28288109%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

PubMed publication ID

28288109

1 reference