(Q38730168)

English

Melatonin synergizes the chemotherapeutic effect of 5-fluorouracil in colon cancer by suppressing PI3K/AKT and NF-κB/iNOS signaling pathways

scientific article published on 19 November 2016

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scholarly article

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Europe PubMed Central

PubMed publication ID

5 September 2017

Melatonin synergizes the chemotherapeutic effect of 5-fluorouracil in colon cancer by suppressing PI3K/AKT and NF-κB/iNOS signaling pathways (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 September 2017

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based on heuristic

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based on heuristic

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author name string

Yue Gao

1

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Europe PubMed Central

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5 September 2017

Xiangsheng Xiao

2

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5 September 2017

Changlin Zhang

3

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5 September 2017

Wendan Yu

4

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5 September 2017

Wei Guo

5

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5 September 2017

Zhifeng Zhang

6

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5 September 2017

Zhenglin Li

7

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5 September 2017

Xu Feng

8

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5 September 2017

Jiaojiao Hao

9

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5 September 2017

Kefang Zhang

10

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5 September 2017

Bingyi Xiao

11

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5 September 2017

Miao Chen

12

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5 September 2017

Wenlin Huang

13

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5 September 2017

Shunbin Xiong

14

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5 September 2017

Xiaojun Wu

15

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5 September 2017

Wuguo Deng

16

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5 September 2017

publication date

19 November 2016

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5 September 2017

Journal of Pineal Research

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5 September 2017

62

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5 September 2017

2

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5 September 2017

Ginsenoside compound K sensitizes human colon cancer cells to TRAIL-induced apoptosis via autophagy-dependent and -independent DR5 upregulation

1 reference

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21 January 2018

Current concepts in rectal cancer

1 reference

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21 January 2018

5-Fluorouracil: mechanisms of action and clinical strategies

1 reference

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21 January 2018

Targeting the DNA replication checkpoint by pharmacologic inhibition of Chk1 kinase: a strategy to sensitize APC mutant colon cancer cells to 5-fluorouracil chemotherapy

1 reference

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21 January 2018

A survey of molecular details in the human pineal gland in the light of phylogeny, structure, function and chronobiological diseases

1 reference

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21 January 2018

Melatonin as an antioxidant: under promises but over delivers

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21 January 2018

Melatonin antioxidative defense: therapeutical implications for aging and neurodegenerative processes

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21 January 2018

Anti-inflammatory effects of melatonin in multiple sclerosis

1 reference

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21 January 2018

Melatonin reduces endothelin-1 expression and secretion in colon cancer cells through the inactivation of FoxO-1 and NF-κβ.

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12380

21 January 2018

Mechanisms of cancer inhibition by melatonin

1 reference

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21 January 2018

Melatonin as a treatment for gastrointestinal cancer: a review.

1 reference

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21 January 2018

Melatonin protects against apoptotic and autophagic cell death in C2C12 murine myoblast cells

1 reference

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21 January 2018

Melatonin potentiates chemotherapy-induced cytotoxicity and apoptosis in rat pancreatic tumor cells

1 reference

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21 January 2018

Melatonin inhibits cell proliferation and induces caspase activation and apoptosis in human malignant lymphoid cell lines.

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12380

21 January 2018

Melatonin induces apoptosis of colorectal cancer cells through HDAC4 nuclear import mediated by CaMKII inactivation

1 reference

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21 January 2018

The impaired myocardial ischemic tolerance in adult offspring of diabetic pregnancy is restored by maternal melatonin treatment

1 reference

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21 January 2018

Melatonin alleviates acute lung injury through inhibiting the NLRP3 inflammasome

1 reference

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21 January 2018

Melatonin overcomes gemcitabine resistance in pancreatic ductal adenocarcinoma by abrogating nuclear factor-κB activation.

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12380

21 January 2018

Melatonin: reducing the toxicity and increasing the efficacy of drugs

1 reference

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21 January 2018

Investigating the role of tumour cell derived iNOS on tumour growth and vasculature in vivo using a tetracycline regulated expression system

1 reference

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21 January 2018

The Expression and Correlation of iNOS and p53 in Oral Squamous Cell Carcinoma

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12380

21 January 2018

Nitric oxide of human colorectal adenocarcinoma cell lines promotes tumour cell invasion.

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12380

21 January 2018

Nitric oxide and TNF-alpha trigger colonic inflammation and carcinogenesis in Helicobacter hepaticus-infected, Rag2-deficient mice

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12380

21 January 2018

Potential of apoptotic pathway-targeted cancer therapeutic research: Where do we stand?

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12380

21 January 2018

Apoptotic pathways as a therapeutic target for colorectal cancer treatment

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12380

21 January 2018

Ghrelin induces colon cancer cell proliferation through the GHS-R, Ras, PI3K, Akt, and mTOR signaling pathways.

1 reference

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21 January 2018

Synergism of PI3K/Akt inhibition and Fas activation on colon cancer cell death

1 reference

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21 January 2018

Simultaneous modulation of COX-2, p300, Akt, and Apaf-1 signaling by melatonin to inhibit proliferation and induce apoptosis in breast cancer cells

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12380

21 January 2018

The expression of iNOS and nitrotyrosine in colitis and colon cancer in humans

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12380

21 January 2018

Melatonin inhibits visfatin-induced inducible nitric oxide synthase expression and nitric oxide production in macrophages

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12380

21 January 2018

Melatonin enhances the anti-tumor effect of fisetin by inhibiting COX-2/iNOS and NF-κB/p300 signaling pathways

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12380

21 January 2018

Regulation of iNOS expression by NF-κB in human lens epithelial cells treated with high levels of glucose

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12380

21 January 2018

Phytic acid attenuates inflammatory responses and the levels of NF-κB and p-ERK in MPTP-induced Parkinson's disease model of mice

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12380

21 January 2018

Efficacy of capecitabine versus 5-fluorouracil in colorectal and gastric cancers: a meta-analysis of individual data from 6171 patients

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12380

21 January 2018

Absorption and distribution characteristics of 5-fluorouracil (5-FU) after an application to the liver surface in rats in order to reduce systemic side effects

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12380

21 January 2018

Chemotherapy for colorectal cancer in the elderly

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12380

21 January 2018

Synergistic antitumor effect of melatonin with several chemotherapeutic drugs on human Ewing sarcoma cancer cells: potentiation of the extrinsic apoptotic pathway

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12380

21 January 2018

Melatonin and doxorubicin synergistically induce cell apoptosis in human hepatoma cell lines

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12380

21 January 2018

Melatonin induces apoptotic death in LNCaP cells via p38 and JNK pathways: therapeutic implications for prostate cancer

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12380

21 January 2018

Melatonin suppresses proinflammatory mediators in lipopolysaccharide-stimulated CRL1999 cells via targeting MAPK, NF-κB, c/EBPβ, and p300 signaling

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12380

21 January 2018

Melatonin potentiates the antiproliferative and pro-apoptotic effects of ursolic acid in colon cancer cells by modulating multiple signaling pathways

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12380

21 January 2018

Apoptosis, Necrosis, and Necroptosis in the Gut and Intestinal Homeostasis

1 reference

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21 January 2018

Synergism between carnosic acid and arsenic trioxide on induction of acute myeloid leukemia cell apoptosis is associated with modulation of PTEN/Akt signaling pathway

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12380

21 January 2018

Inducible nitric oxide synthase drives mTOR pathway activation and proliferation of human melanoma by reversible nitrosylation of TSC2.

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12380

21 January 2018

Nitric oxide in cancer metastasis

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12380

21 January 2018

Identification of a classic cytokine-induced enhancer upstream in the human iNOS promoter

1 reference

https://api.crossref.org/works/10.1111%2FJPI.12380

21 January 2018

Identification of hamster inducible nitric oxide synthase (iNOS) promoter sequences that influence basal and inducible iNOS expression

1 reference

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21 January 2018

Identifiers

10.1111/JPI.12380

1 reference

Europe PubMed Central

PubMed publication ID

5 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 September 2017

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