(Q38743303)

English

Loss of HDAC-Mediated Repression and Gain of NF-κB Activation Underlie Cytokine Induction in ARID1A- and PIK3CA-Mutation-Driven Ovarian Cancer

scientific article published on September 2016

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scholarly article

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Europe PubMed Central

PubMed publication ID

6 September 2017

Loss of HDAC-Mediated Repression and Gain of NF-κB Activation Underlie Cytokine Induction in ARID1A- and PIK3CA-Mutation-Driven Ovarian Cancer (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

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1 reference

based on heuristic

inferred from title

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27681437%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

2

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27681437%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

author name string

Yi Zhang

3

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27681437%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

publication date

1 September 2016

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Europe PubMed Central

PubMed publication ID

6 September 2017

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27681437%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

17

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27681437%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27681437%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

275-288

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27681437%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivator

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CREB-binding protein/p300 are transcriptional coactivators of p65

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histone deacetylases and SAP18, a novel polypeptide, are components of a human Sin3 complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The dermatomyositis-specific autoantigen Mi2 is a component of a complex containing histone deacetylase and nucleosome remodeling activities

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of NF-kappaB by the Akt/PKB kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The IKK NF-kappa B system: a treasure trove for drug development

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A genetically defined model for human ovarian cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brahma links the SWI/SNF chromatin-remodeling complex with MeCP2-dependent transcriptional silencing

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear factor-kappaB inhibitors as sensitizers to anticancer drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant PIK3CA promotes cell growth and invasion of human cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mouse model of human ovarian endometrioid adenocarcinoma based on somatic defects in the Wnt/beta-catenin and PI3K/Pten signaling pathways.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-6 involvement in epithelial cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An HMM approach to genome-wide identification of differential histone modification sites from ChIP-seq data

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The interleukin-8 pathway in cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TopHat: discovering splice junctions with RNA-Seq

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The biology of ovarian cancer: new opportunities for translation

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dangerous liaisons: STAT3 and NF-kappaB collaboration and crosstalk in cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of an ovarian clear cell carcinoma gene signature that reflects inherent disease biology and the carcinogenic processes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tobacco smoke promotes lung tumorigenesis by triggering IKKbeta- and JNK1-dependent inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase II trial of the histone deacetylase inhibitor belinostat in women with platinum resistant epithelial ovarian cancer and micropapillary (LMP) ovarian tumours.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ARID1A mutations in endometriosis-associated ovarian carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Non-canonical NF-κB signaling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SWI/SNF nucleosome remodellers and cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer biology and NuRD: a multifaceted chromatin remodelling complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of ARID1A protein expression occurs as an early event in ovarian clear-cell carcinoma development and frequently coexists with PIK3CA mutations.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New molecular bridge between RelA/p65 and NF-κB target genes via histone acetyltransferase TIP60 cofactor

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fast gapped-read alignment with Bowtie 2

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A CXCL1 paracrine network links cancer chemoresistance and metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An expansive human regulatory lexicon encoded in transcription factor footprints

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular basis of NF-κB signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ARID1A mutations and PI3K/AKT pathway alterations in endometriosis and endometriosis-associated ovarian carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Refined DNase-seq protocol and data analysis reveals intrinsic bias in transcription factor footprint identification

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecularly-targeted Strategy and NF-κB in lymphoid malignancies

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of the interleukin 6 receptor family in epithelial ovarian cancer and its clinical implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NF-κB, an active player in human cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coexistent ARID1A-PIK3CA mutations promote ovarian clear-cell tumorigenesis through pro-tumorigenic inflammatory cytokine signalling

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomics

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inactivating ARID1A Tumor Suppressor Enhances TERT Transcription and Maintains Telomere Length in Cancer Cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27681437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.CELREP.2016.09.003

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27681437%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27681437%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

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