(Q38743867)

6 September 2017

title

Targeting glutamate signalling in depression: progress and prospects (English)

1 reference

6 September 2017

Chadi G Abdallah

2

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author name string

James W Murrough

series ordinal

1

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6 September 2017

Sanjay J Mathew

series ordinal

3

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6 September 2017

language of work or name

1 reference

17 March 2017

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Nature Reviews Drug Discovery

6 September 2017

published in

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6 September 2017

volume

16

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6 September 2017

issue

7

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6 September 2017

page(s)

472-486

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https://scigraph.springernature.com/pub.10.1038/nrd.2017.16

6 September 2017

exact match

0 references

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Inhibition of glycogen synthase kinase-3 is necessary for the rapid antidepressant effect of ketamine in mice

21 January 2018

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GSK-3 inhibition potentiates the synaptogenic and antidepressant-like effects of subthreshold doses of ketamine

21 January 2018

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21 January 2018

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21 January 2018

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Neural correlates of rapid antidepressant response to ketamine in bipolar disorder.

21 January 2018

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Brain-derived neurotrophic factor and initial antidepressant response to an N-methyl-D-aspartate antagonist.

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Sleep homeostasis and cortical synchronization: I. Modeling the effects of synaptic strength on sleep slow waves

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Concomitant BDNF and sleep slow wave changes indicate ketamine-induced plasticity in major depressive disorder

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Single-dose ketamine followed by daily D-Cycloserine in treatment-resistant bipolar depression

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21 January 2018

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GLYX-13, a NMDA receptor glycine-site functional partial agonist, induces antidepressant-like effects without ketamine-like side effects

21 January 2018

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Randomized proof of concept trial of GLYX-13, an N-methyl-D-aspartate receptor glycine site partial agonist, in major depressive disorder nonresponsive to a previous antidepressant agent

21 January 2018

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7-Chlorokynurenic acid is a selective antagonist at the glycine modulatory site of the N-methyl-D-aspartate receptor complex

21 January 2018

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Deuterated drugs draw heavier backing.

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Inhibition of glycine transporter-I as a novel mechanism for the treatment of depression

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Maximum tolerated dose evaluation of the AMPA modulator Org 26576 in healthy volunteers and depressed patients: a summary and method analysis of bridging research in support of phase II dose selection

21 January 2018

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Examination of Org 26576, an AMPA receptor positive allosteric modulator, in patients diagnosed with major depressive disorder: an exploratory, randomized, double-blind, placebo-controlled trial

21 January 2018

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mGluR2/3 blockade produces rapid and long-lasting reversal of anhedonia caused by chronic stress exposure

21 January 2018

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The Rapidly Acting Antidepressant Ketamine and the mGlu2/3 Receptor Antagonist LY341495 Rapidly Engage Dopaminergic Mood Circuits

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ABCB1 gene variants and antidepressant treatment outcome: A meta-analysis

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A randomized trial of a low-trapping nonselective N-methyl-D-aspartate channel blocker in major depression

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Chronic ketamine administration modulates midbrain dopamine system in mice

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21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.16

Does intraoperative ketamine attenuate inflammatory reactivity following surgery? A systematic review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.16

Altered thalamocortical rhythmicity and connectivity in mice lacking CaV3.1 T-type Ca2+ channels in unconsciousness

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.16

Driving AMPA receptors into synapses by LTP and CaMKII: requirement for GluR1 and PDZ domain interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.16

Ionotropic and metabotropic glutamate receptor structure and pharmacology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.16

Functional antagonists at the NMDA receptor complex exhibit antidepressant actions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.16

Inescapable versus escapable shock modulates long-term potentiation in the rat hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.16

Glutamate-based antidepressants: 20 years on.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.16

Adaptation of N-methyl-D-aspartate (NMDA) receptors following antidepressant treatment: implications for the pharmacotherapy of depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.16

A randomized add-on trial of an N-methyl-D-aspartate antagonist in treatment-resistant bipolar depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.16

Replication of ketamine's antidepressant efficacy in bipolar depression: a randomized controlled add-on trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.16

Rapid increase of an immediate early gene messenger RNA in hippocampal neurons by synaptic NMDA receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.16

Alterations in the N-methyl-d-asparatate (NMDA) receptor complex in the frontal cortex of suicide victims

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.16

The stressed synapse: the impact of stress and glucocorticoids on glutamate transmission

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.16

GLYX-13 Produces Rapid Antidepressant Responses with Key Synaptic and Behavioral Effects Distinct from Ketamine.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.16

In search of the mechanisms of ketamine’s antidepressant effects: How robust is the evidence behind the mTor activation hypothesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.16

Temporal Dynamics of Antidepressant Ketamine Effects on Glutamine Cycling Follow Regional Fingerprints of AMPA and NMDA Receptor Densities.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.16

Ketamine Treatment and Global Brain Connectivity in Major Depression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.16

Cyloserine as an antidepressant agent

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.16

Antidepressant-like effects of 1-aminocyclopropanecarboxylic acid and D-cycloserine in an animal model of depression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.16

31 March 2020

Identifiers

DOI

10.1038/NRD.2017.16

1 reference

6 September 2017

1 reference