(Q38752693)

23 May 2018

title

Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals (English)

1 reference

23 May 2018

author

Robert W. Williams

5

1 reference

23 May 2018

Davide D'Amico

Davide D'Amico

4

0 references

Miguel A Prado

Miguel A Prado

2

0 references

Pedro M Quirós

Pedro M Quirós

1

0 references

Steven P. Gygi

7

Steven P Gygi

1 reference

23 May 2018

Nicola Zamboni

3

Nicola Zamboni

1 reference

23 May 2018

author name string

Daniel Finley

6

1 reference

23 May 2018

language of work or name

English

0 references

publication date

31 May 2017

1 reference

23 May 2018

number of pages

19

1 reference

based on heuristic

inferred from page(s)

published in

Journal of Cell Biology

1 reference

23 May 2018

volume

216

1 reference

23 May 2018

issue

7

1 reference

23 May 2018

page(s)

2027-2045

1 reference

23 May 2018

describes a project that uses

cites work

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23 June 2018

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Proteome-wide quantitative multiplexed profiling of protein expression: carbon-source dependency in Saccharomyces cerevisiae

23 June 2018

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New roles for mitochondrial proteases in health, ageing and disease

23 June 2018

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Coordination of mitophagy and mitochondrial biogenesis during ageing in C. elegans

23 June 2018

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Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response

23 June 2018

1 reference

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Tetracyclines Disturb Mitochondrial Function across Eukaryotic Models: A Call for Caution in Biomedical Research

23 June 2018

1 reference

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Inhibition of mitochondrial genome expression triggers the activation of CHOP-10 by a cell signaling dependent on the integrated stress response but not the mitochondrial unfolded protein response.

23 June 2018

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limma powers differential expression analyses for RNA-sequencing and microarray studies

23 June 2018

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HTSeq--a Python framework to work with high-throughput sequencing data

23 June 2018

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Improved vectors and genome-wide libraries for CRISPR screening

23 June 2018

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MultiNotch MS3 enables accurate, sensitive, and multiplexed detection of differential expression across cancer cell line proteomes.

23 June 2018

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A method to identify and validate mitochondrial modulators using mammalian cells and the worm C. elegans

23 June 2018

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A mitochondrial RNAi screen defines cellular bioenergetic determinants and identifies an adenylate kinase as a key regulator of ATP levels

23 June 2018

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Pathogenesis of human mitochondrial diseases is modulated by reduced activity of the ubiquitin/proteasome system

23 June 2018

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Caenorhabditis elegans pathways that surveil and defend mitochondria

23 June 2018

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Tissue-specific loss of DARS2 activates stress responses independently of respiratory chain deficiency in the heart

23 June 2018

1 reference

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Regulation of autophagy by cytosolic acetyl-coenzyme A.

23 June 2018

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Stress-induced OMA1 activation and autocatalytic turnover regulate OPA1-dependent mitochondrial dynamics

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5496626

Stress-regulated translational attenuation adapts mitochondrial protein import through Tim17A degradation.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5496626

Muscle mitohormesis promotes longevity via systemic repression of insulin signaling

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5496626

Mitochondrial cristae shape determines respiratory chain supercomplexes assembly and respiratory efficiency

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5496626

Loss of mitochondrial peptidase Clpp leads to infertility, hearing loss plus growth retardation via accumulation of CLPX, mtDNA and inflammatory factors

23 June 2018

1 reference

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Epigenetic silencing mediates mitochondria stress-induced longevity

23 June 2018

1 reference

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23 June 2018

The hallmarks of aging

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The Genotype-Tissue Expression (GTEx) project

23 June 2018

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Mitonuclear protein imbalance as a conserved longevity mechanism

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5496626

Pharmacological approaches to restore mitochondrial function

23 June 2018

1 reference

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ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death.

23 June 2018

1 reference

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TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

23 June 2018

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A small molecule inhibitor of redox-regulated protein translocation into mitochondria

23 June 2018

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The mitochondrial unfolded protein response activator ATFS-1 protects cells from inhibition of the mevalonate pathway

23 June 2018

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Increased proteasome activity in human embryonic stem cells is regulated by PSMD11

23 June 2018

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23 June 2018

1 reference

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Protective coupling of mitochondrial function and protein synthesis via the eIF2α kinase GCN-2

23 June 2018

1 reference

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Mitochondrial import efficiency of ATFS-1 regulates mitochondrial UPR activation.

23 June 2018

1 reference

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Monogenic mitochondrial disorders

23 June 2018

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Loss of mitochondrial protease OMA1 alters processing of the GTPase OPA1 and causes obesity and defective thermogenesis in mice

23 June 2018

1 reference

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23 June 2018

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Fast gapped-read alignment with Bowtie 2

23 June 2018

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The mitochondrial ATP-dependent Lon protease: a novel target in lymphoma death mediated by the synthetic triterpenoid CDDO and its derivatives

23 June 2018

1 reference

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The unfolded protein response: controlling cell fate decisions under ER stress and beyond

23 June 2018

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NCoR1 is a conserved physiological modulator of muscle mass and oxidative function

23 June 2018

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Renal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: roles for fumarate in KEAP1 succination and Nrf2 signaling

23 June 2018

1 reference

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The cell-non-autonomous nature of electron transport chain-mediated longevity

23 June 2018

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A tissue-specific atlas of mouse protein phosphorylation and expression

23 June 2018

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Metabolic networks of longevity

23 June 2018

1 reference

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Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities

23 June 2018

1 reference

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edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

23 June 2018

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Dissection of a QTL hotspot on mouse distal chromosome 1 that modulates neurobehavioral phenotypes and gene expression

23 June 2018

1 reference

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CHR-2797: an antiproliferative aminopeptidase inhibitor that leads to amino acid deprivation in human leukemic cells

23 June 2018

1 reference

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Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization

23 June 2018

1 reference

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OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion

23 June 2018

1 reference

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From genomics to chemical genomics: new developments in KEGG

23 June 2018

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R/qtl: QTL mapping in experimental crosses

23 June 2018

1 reference

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An integrated stress response regulates amino acid metabolism and resistance to oxidative stress

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5496626

Translational control in the endoplasmic reticulum stress response

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5496626

A mitochondrial specific stress response in mammalian cells

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5496626

Heme-regulated eIF2alpha kinase (HRI) is required for translational regulation and survival of erythroid precursors in iron deficiency

23 June 2018

1 reference

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Essential role for the dsRNA-dependent protein kinase PKR in innate immunity to viral infection

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5496626

Perk is essential for translational regulation and cell survival during the unfolded protein response

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5496626

On auxotrophy for pyrimidines of respiration-deficient chick embryo cells.

23 June 2018

1 reference

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Analysis of mtDNA/nDNA Ratio in Mice.

23 June 2018

1 reference

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Mistargeted mitochondrial proteins activate a proteostatic response in the cytosol.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5496626

AMPK and GCN2-ATF4 signal the repression of mitochondria in colon cancer cells.

31 August 2018

1 reference

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High-throughput, accurate mass metabolome profiling of cellular extracts by flow injection-time-of-flight mass spectrometry.

31 August 2018

1 reference

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Mitochondrial myopathy induces a starvation-like response

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5496626

Mitochondrial dysfunction triggered by loss of HtrA2 results in the activation of a brain-specific transcriptional stress response

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5496626

ClpP mediates activation of a mitochondrial unfolded protein response in C. elegans

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5496626

Compartment-specific perturbation of protein handling activates genes encoding mitochondrial chaperones

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5496626

ATP-Dependent Lon Protease Controls Tumor Bioenergetics by Reprogramming Mitochondrial Activity

31 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1083%2FJCB.201702058

Selective induction of mitochondrial chaperones in response to loss of the mitochondrial genome

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28566324

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1083/JCB.201702058

1 reference

23 May 2018

PMC publication ID

5496626

1 reference

23 May 2018

PubMed publication ID

28566324

1 reference

23 May 2018