(Q38765948)

6 September 2017

Mitonuclear communication in homeostasis and stress (English)

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6 September 2017

2

Adrienne Mottis

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Johan Auwerx

series ordinal

3

object named as

Johan Auwerx

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Pedro M Quirós

series ordinal

1

object named as

Pedro M Quirós

1 reference

6 September 2017

language of work or name

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9 March 2016

1 reference

Nature Reviews Molecular Cell Biology

6 September 2017

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6 September 2017

17

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6 September 2017

213-226

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6 September 2017

4

1 reference

https://scigraph.springernature.com/pub.10.1038/nrm.2016.23

6 September 2017

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NRF-2 transcription factor is required for human TOMM20 gene expression.

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Integrating mitochondrial translation into the cellular context

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Peroxisome-Proliferator-Activated Receptor δ Activates Fat Metabolism to Prevent Obesity

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Activation of peroxisome proliferator-activated receptor delta induces fatty acid beta-oxidation in skeletal muscle and attenuates metabolic syndrome

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International Union of Pharmacology. LXI. Peroxisome proliferator-activated receptors

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Genome-wide orchestration of cardiac functions by the orphan nuclear receptors ERRalpha and gamma.

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ERRgamma directs and maintains the transition to oxidative metabolism in the postnatal heart.

31 March 2020

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Transcriptional coregulators: fine-tuning metabolism

31 March 2020

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Regulation of PGC-1α, a nodal regulator of mitochondrial biogenesis

31 March 2020

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Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism

31 March 2020

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NCoR1 is a conserved physiological modulator of muscle mass and oxidative function

31 March 2020

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The transcriptional corepressor RIP140 regulates oxidative metabolism in skeletal muscle

31 March 2020

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AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

31 March 2020

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Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle

31 March 2020

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Gain-of-function R225Q mutation in AMP-activated protein kinase gamma3 subunit increases mitochondrial biogenesis in glycolytic skeletal muscle

31 March 2020

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Regulation of mitochondrial biogenesis in skeletal muscle by CaMK

31 March 2020

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Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells.

31 March 2020

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Telomere dysfunction induces metabolic and mitochondrial compromise.

31 March 2020

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On PAR with PARP: cellular stress signaling through poly(ADP-ribose) and PARP-1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

The retrograde response: when mitochondrial quality control is not enough

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Mitochondrial retrograde signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Mitochondria-to-nuclear signaling is regulated by the subcellular localization of the transcription factors Rtg1p and Rtg3p

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

The yeast retrograde response as a model of intracellular signaling of mitochondrial dysfunction

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRM.2016.23

Rewiring AMPK and mitochondrial retrograde signaling for metabolic control of aging and histone acetylation in respiratory-defective cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

The mitochondrial ribosomal protein of the large subunit, Afo1p, determines cellular longevity through mitochondrial back-signaling via TOR1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Absence of mitochondrial translation control proteins extends life span by activating sirtuin-dependent silencing.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Aging networks in Caenorhabditis elegans: AMP-activated protein kinase (aak-2) links multiple aging and metabolism pathways.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Malate and fumarate extend lifespan in Caenorhabditis elegans

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Increased longevity of some C. elegans mitochondrial mutants explained by activation of an alternative energy-producing pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Reduced mammalian target of rapamycin activity facilitates mitochondrial retrograde signaling and increases life span in normal human fibroblasts

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Mitochondria as sensors and regulators of calcium signalling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

CREB activation induced by mitochondrial dysfunction is a new signaling pathway that impairs cell proliferation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Compromised mitochondrial function leads to increased cytosolic calcium and to activation of MAP kinases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Mitochondrial stress-induced calcium signaling, phenotypic changes and invasive behavior in human lung carcinoma A549 cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Disruption of cytochrome c oxidase function induces the Warburg effect and metabolic reprogramming

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Mitochondria to nucleus stress signaling: a distinctive mechanism of NFkappaB/Rel activation through calcineurin-mediated inactivation of IkappaBbeta

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Retrograde Ca2+ signaling in C2C12 skeletal myocytes in response to mitochondrial genetic and metabolic stress: a novel mode of inter-organelle crosstalk

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

The mitochondrial ATPase inhibitory factor 1 triggers a ROS-mediated retrograde prosurvival and proliferative response

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Mitochondria-to-nucleus stress signaling induces phenotypic changes, tumor progression and cell invasion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Mitochondrial dysfunction induces aberrant insulin signalling and glucose utilisation in murine C2C12 myotube cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Activation of Akt is essential for the propagation of mitochondrial respiratory stress signaling and activation of the transcriptional coactivator heterogeneous ribonucleoprotein A2

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

ROS function in redox signaling and oxidative stress

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Mitochondrial ROS signaling in organismal homeostasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Altered quinone biosynthesis in the long-lived clk-1 mutants of Caenorhabditis elegans.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Inhibition of respiration extends C. elegans life span via reactive oxygen species that increase HIF-1 activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

The C. elegans p38 MAPK pathway regulates nuclear localization of the transcription factor SKN-1 in oxidative stress response

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Impaired insulin/IGF1 signaling extends life span by promoting mitochondrial L-proline catabolism to induce a transient ROS signal

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Mitochondrial hormesis links low-dose arsenite exposure to lifespan extension

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

A nuclear role for the respiratory enzyme CLK-1 in regulating mitochondrial stress responses and longevity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Distinct mitochondrial retrograde signals control the G1-S cell cycle checkpoint

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Muscle mitohormesis promotes longevity via systemic repression of insulin signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

ZNF143 transcription factor mediates cell survival through upregulation of the GPX1 activity in the mitochondrial respiratory dysfunction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Induction of cytoprotective genes through Nrf2/antioxidant response element pathway: a new therapeutic approach for the treatment of inflammatory diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Foxo3a inhibits cardiomyocyte hypertrophy through transactivating catalase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

A systems approach for decoding mitochondrial retrograde signaling pathways.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

ROS-triggered phosphorylation of complex II by Fgr kinase regulates cellular adaptation to fuel use

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

DJ-1 links muscle ROS production with metabolic reprogramming and systemic energy homeostasis in mice.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

New roles for mitochondrial proteases in health, ageing and disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

The mitochondrial unfolded protein response, a conserved stress response pathway with implications in health and disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Mitonuclear protein imbalance as a conserved longevity mechanism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

The cell-non-autonomous nature of electron transport chain-mediated longevity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

The NAD(+)/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Pharmacological Inhibition of poly(ADP-ribose) polymerases improves fitness and mitochondrial function in skeletal muscle

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

The matrix peptide exporter HAF-1 signals a mitochondrial UPR by activating the transcription factor ZC376.7 in C. elegans

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Mitochondrial import efficiency of ATFS-1 regulates mitochondrial UPR activation.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Ubiquitin-like protein 5 positively regulates chaperone gene expression in the mitochondrial unfolded protein response

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

ClpP mediates activation of a mitochondrial unfolded protein response in C. elegans.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Mitochondrial and nuclear accumulation of the transcription factor ATFS-1 promotes OXPHOS recovery during the UPR(mt).

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Genetic analysis of mitochondrial protein misfolding in Drosophila melanogaster

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

The chop gene contains an element for the positive regulation of the mitochondrial unfolded protein response

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

A mitochondrial specific stress response in mammalian cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Discovery of genes activated by the mitochondrial unfolded protein response (mtUPR) and cognate promoter elements

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

The loss of LRPPRC function induces the mitochondrial unfolded protein response

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

SirT3 regulates the mitochondrial unfolded protein response

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

ClpX stimulates the mitochondrial unfolded protein response (UPRmt) in mammalian cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Exploiting the mitochondrial unfolded protein response for cancer therapy in mice and human cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Tissue-specific loss of DARS2 activates stress responses independently of respiratory chain deficiency in the heart

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Mitochondrial fission and fusion factors reciprocally orchestrate mitophagic culling in mouse hearts and cultured fibroblasts

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Effective treatment of mitochondrial myopathy by nicotinamide riboside, a vitamin B3

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

A SIRT7-dependent acetylation switch of GABPβ1 controls mitochondrial function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Stem cell aging. A mitochondrial UPR-mediated metabolic checkpoint regulates hematopoietic stem cell aging

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Multilayered genetic and omics dissection of mitochondrial activity in a mouse reference population

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Estrogen receptor mediates a distinct mitochondrial unfolded protein response

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Transcriptional activation of LON Gene by a new form of mitochondrial stress: A role for the nuclear respiratory factor 2 in StAR overload response (SOR).

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

StAR enhances transcription of genes encoding the mitochondrial proteases involved in its own degradation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Heat shock factors: integrators of cell stress, development and lifespan.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Mitochondrial SSBP1 protects cells from proteotoxic stresses by potentiating stress-induced HSF1 transcriptional activity.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Regulated translation initiation controls stress-induced gene expression in mammalian cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

An integrated stress response regulates amino acid metabolism and resistance to oxidative stress

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

The eIF2α kinases: their structures and functions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Phosphorylation of eIF2 facilitates ribosomal bypass of an inhibitory upstream ORF to enhance CHOP translation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Protective coupling of mitochondrial function and protein synthesis via the eIF2α kinase GCN-2

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Stress-regulated translational attenuation adapts mitochondrial protein import through Tim17A degradation.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Inhibition of mitochondrial genome expression triggers the activation of CHOP-10 by a cell signaling dependent on the integrated stress response but not the mitochondrial unfolded protein response.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Tetracyclines Disturb Mitochondrial Function across Eukaryotic Models: A Call for Caution in Biomedical Research

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Tetracyclines cause cell stress-dependent ATF4 activation and mTOR inhibition

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Mitochondrial dysfunction triggered by loss of HtrA2 results in the activation of a brain-specific transcriptional stress response

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

A sustained deficiency of mitochondrial respiratory complex III induces an apoptotic cell death through the p53-mediated inhibition of pro-survival activities of the activating transcription factor 4.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

AMPK and GCN2-ATF4 signal the repression of mitochondria in colon cancer cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Inhibition of mitochondrial function induces an integrated stress response in oligodendroglia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Aberrant Schwann cell lipid metabolism linked to mitochondrial deficits leads to axon degeneration and neuropathy.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

A cytosolic network suppressing mitochondria-mediated proteostatic stress and cell death

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Mistargeted mitochondrial proteins activate a proteostatic response in the cytosol.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Extension of Drosophila life span by RNAi of the mitochondrial respiratory chain

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Humanin: a harbinger of mitochondrial-derived peptides?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Aβ

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Fibroblast growth factor 21 regulates energy metabolism by activating the AMPK-SIRT1-PGC-1alpha pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Mitochondrial myopathy induces a starvation-like response

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

FGF-21 as a biomarker for muscle-manifesting mitochondrial respiratory chain deficiencies: a diagnostic study.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

31 March 2020

The hallmarks of aging

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Mitochondria: in sickness and in health

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Mitochondrial electron transport is a key determinant of life span in Caenorhabditis elegans

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

A mitochondrial superoxide signal triggers increased longevity in Caenorhabditis elegans

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Feedback regulation via AMPK and HIF-1 mediates ROS-dependent longevity in Caenorhabditis elegans

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

CEP-1, the Caenorhabditis elegans p53 homolog, mediates opposing longevity outcomes in mitochondrial electron transport chain mutants

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

The homeobox protein CEH-23 mediates prolonged longevity in response to impaired mitochondrial electron transport chain in C. elegans

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Coordination of mitophagy and mitochondrial biogenesis during ageing in C. elegans

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Unraveling the truth about antioxidants: mitohormesis explains ROS-induced health benefits

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

The HIF-1 hypoxia-inducible factor modulates lifespan in C. elegans

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Caenorhabditis elegans lifespan extension caused by treatment with an orally active ROS-generator is dependent on DAF-16 and SIR-2.1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

The Caenorhabditis elegans AMP-activated protein kinase AAK-2 is phosphorylated by LKB1 and is required for resistance to oxidative stress and for normal motility and foraging behavior

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Mitochondrial and cytoplasmic ROS have opposing effects on lifespan

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Evolutionary conservation of the clk-1-dependent mechanism of longevity: loss of mclk1 increases cellular fitness and lifespan in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Early mitochondrial dysfunction in long-lived Mclk1+/- mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Increased longevity and refractoriness to Ca(2+)-dependent neurodegeneration in Surf1 knockout mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Post-transcriptional silencing and functional characterization of the Drosophila melanogaster homolog of human Surf1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Complex IV-deficient Surf1(-/-) mice initiate mitochondrial stress responses

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Mild mitochondrial uncoupling in mice affects energy metabolism, redox balance and longevity.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Gene expression profiling implicates OXPHOS complexes in lifespan extension of flies over-expressing a small mitochondrial chaperone, Hsp22.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Pharmacological approaches to restore mitochondrial function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

The Convergence of Systems and Reductionist Approaches in Complex Trait Analysis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Organellar non-coding RNAs: emerging regulation mechanisms

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

A new pathway for mitochondrial quality control: mitochondrial-derived vesicles

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Mitochondria in innate immunity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Caenorhabditis elegans pathways that surveil and defend mitochondria

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Mitochondrial UPR-regulated innate immunity provides resistance to pathogen infection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Mitochondrial DNA stress primes the antiviral innate immune response

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

TLR signalling augments macrophage bactericidal activity through mitochondrial ROS.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Elevated mitochondrial reactive oxygen species generation affects the immune response via hypoxia-inducible factor-1alpha in long-lived Mclk1+/- mouse mutants

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

An enhanced immune response of Mclk1⁺/⁻ mutant mice is associated with partial protection from fibrosis, cancer and the development of biomarkers of aging.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

The ubiquitin ligase parkin mediates resistance to intracellular pathogens

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Mitochondrial Respiration Controls Lysosomal Function during Inflammatory T Cell Responses.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Oxaloacetate supplementation increases lifespan in Caenorhabditis elegans through an AMPK/FOXO-dependent pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Rates of behavior and aging specified by mitochondrial function during development

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Two modes of mitochondrial dysfunction lead independently to lifespan extension in Caenorhabditis elegans.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Drosophila sbo regulates lifespan through its function in the synthesis of coenzyme Q in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

C. elegans longevity pathways converge to decrease mitochondrial membrane potential.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2016.23

Interorganelle signaling is a determinant of longevity in Saccharomyces cerevisiae

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26956194

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mutations in the clk-1 gene of Caenorhabditis elegans affect developmental and behavioral timing.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26956194

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRM.2016.23

1 reference

Dimensions Publication ID

6 September 2017

1007596707

0 references

Fatcat ID

release_aocokbr2jrgyverzxpmy6vcbha

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/aocokbr2jrgyverzxpmy6vcbha

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference