Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q28116902)
Watch
English
The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance
scientific journal article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
PubMed
PubMed ID
25738459
retrieved
4 January 2017
title
The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance
(English)
1 reference
stated in
PubMed
PubMed ID
25738459
retrieved
4 January 2017
main subject
obesity
0 references
purine-containing compound biosynthetic process
1 reference
stated in
GOA release 2020-03-11
mitochondrion
1 reference
based on heuristic
inferred from title
preproinsulin
1 reference
based on heuristic
inferred from title
insulin resistance
1 reference
based on heuristic
inferred from title
author
Pinchas Cohen
series ordinal
11
0 references
Tamer Sallam
object named as
Tamer Sallam
series ordinal
4
0 references
Rafael de Cabo
object named as
Rafael de Cabo
series ordinal
10
0 references
Junxiang Wan
series ordinal
6
object named as
Junxiang Wan
1 reference
stated in
PubMed
PubMed ID
25738459
retrieved
4 January 2017
author name string
Changhan Lee
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
25738459
retrieved
4 January 2017
Jennifer Zeng
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
25738459
retrieved
4 January 2017
Brian G. Drew
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
25738459
retrieved
4 January 2017
Alejandro Martin-Montalvo
series ordinal
5
1 reference
stated in
PubMed
PubMed ID
25738459
retrieved
4 January 2017
Su-Jeong Kim
series ordinal
7
1 reference
stated in
PubMed
PubMed ID
25738459
retrieved
4 January 2017
Hemal Mehta
series ordinal
8
1 reference
stated in
PubMed
PubMed ID
25738459
retrieved
4 January 2017
Andrea L. Hevener
series ordinal
9
1 reference
stated in
PubMed
PubMed ID
25738459
retrieved
4 January 2017
publication date
3 March 2015
1 reference
stated in
PubMed
PubMed ID
25738459
retrieved
4 January 2017
published in
Cell Metabolism
1 reference
stated in
PubMed
PubMed ID
25738459
retrieved
4 January 2017
volume
21
1 reference
stated in
PubMed
PubMed ID
25738459
retrieved
4 January 2017
page(s)
443–454
1 reference
stated in
PubMed
PubMed ID
25738459
retrieved
4 January 2017
issue
3
1 reference
stated in
PubMed
PubMed ID
25738459
retrieved
4 January 2017
cites work
Continued colonization of the human genome by mitochondrial DNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
20 March 2017
Humanin: a novel central regulator of peripheral insulin action
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
20 March 2017
Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
20 March 2017
Interaction between the Alzheimer's survival peptide humanin and insulin-like growth factor-binding protein 3 regulates cell survival and apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
20 March 2017
Humanin peptide suppresses apoptosis by interfering with Bax activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
20 March 2017
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
20 March 2017
A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Aβ
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
20 March 2017
Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
20 March 2017
PAGE: parametric analysis of gene set enrichment
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
20 March 2017
Characterization of 954 bovine full-CDS cDNA sequences.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
20 March 2017
Mitohormesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
20 March 2017
Metformin in breast cancer: time for action
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
20 March 2017
Not so different after all: a comparison of methods for detecting amino acid sites under selection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
20 March 2017
Circumventing the Crabtree Effect: Replacing Media Glucose with Galactose Increases Susceptibility of HepG2 Cells to Mitochondrial Toxicants
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
7 April 2017
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
7 April 2017
Physiological roles of mitochondrial reactive oxygen species
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
7 April 2017
The cell-non-autonomous nature of electron transport chain-mediated longevity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
7 April 2017
The biochemistry and cell biology of aging: metabolic regulation through mitochondrial signaling.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
29 September 2017
Potent humanin analog increases glucose-stimulated insulin secretion through enhanced metabolism in the β cell.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
29 September 2017
Metformin improves healthspan and lifespan in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
29 September 2017
AICAR inhibits oxygen consumption by intact skeletal muscle cells in culture
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
29 September 2017
Metformin retards aging in C. elegans by altering microbial folate and methionine metabolism.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
29 September 2017
The role of mitochondria in aging
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
29 September 2017
Humanin: a harbinger of mitochondrial-derived peptides?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
29 September 2017
Metabolism of inflammation limited by AMPK and pseudo-starvation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
29 September 2017
Peptidomic discovery of short open reading frame-encoded peptides in human cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
29 September 2017
Metabolomic fingerprint reveals that metformin impairs one-carbon metabolism in a manner similar to the antifolate class of chemotherapy drugs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
29 September 2017
SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
29 September 2017
The metabolic footprint of aging in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
29 September 2017
Bioenergetic origins of complexity and disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
29 September 2017
The human mitochondrial transcriptome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
29 September 2017
Metformin: an old medication of new fashion: evolving new molecular mechanisms and clinical implications in polycystic ovary syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
29 September 2017
AMPK in Health and Disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
29 September 2017
Effect of long-term caloric restriction on oxygen consumption and body temperature in two different strains of mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
29 September 2017
Peptides encoded by short ORFs control development and define a new eukaryotic gene family
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
29 September 2017
AMP-activated protein kinase and the regulation of glucose transport
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
29 September 2017
The abundance of short proteins in the mammalian proteome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
29 September 2017
Aging of mesenchymal stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
29 September 2017
Tissue microarrays in drug discovery
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
29 September 2017
The Crabtree effect: a review
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
29 September 2017
Analysis of microarray data using Z score transformation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
29 September 2017
Presence of mitochondria-type ribosomes outside mitochondria in germ plasm of Drosophila embryos
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
29 September 2017
Banting Lecture. Insulin action, diabetogenes, and the cause of type II diabetes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
29 September 2017
The majority of cDNA clones with strong positive signals for the interferon-induction-specific sequences resemble mitochondrial ribosomal RNA genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
29 September 2017
Mitochondrial origin of membrane-associated heterogeneous RNA in HeLa cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
29 September 2017
Conserved regulation of cardiac calcium uptake by peptides encoded in small open reading frames
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
2 June 2018
Human mitochondrial tRNAMet is exported to the cytoplasm and associates with the Argonaute 2 protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
2 June 2018
Requirement for a noncoding RNA in Drosophila polar granules for germ cell establishment
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
2 June 2018
New role for the mitochondrial peptide humanin: protective agent against chemotherapy-induced side effects
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
27 November 2018
Metformin trims fats to restore insulin sensitivity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
27 November 2018
A mitochondrial ribosomal and RNA decay pathway blocks cell proliferation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
27 November 2018
Small peptides switch the transcriptional activity of Shavenbaby during Drosophila embryogenesis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
27 November 2018
Methotrexate--how does it really work?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
27 November 2018
Establishment of human cell lines lacking mitochondrial DNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
27 November 2018
Untargeted metabolomic profiling as an evaluative tool of fenofibrate-induced toxicology in Fischer 344 male rats.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
27 November 2018
A segmentation gene in tribolium produces a polycistronic mRNA that codes for multiple conserved peptides
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
27 November 2018
Mitochondrial small ribosomal RNA is present on polar granules in early cleavage embryos of Drosophila melanogaster.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
27 November 2018
Presence of mitochondrial large ribosomal RNA outside mitochondria in germ plasm of Drosophila melanogaster.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4350682
retrieved
27 November 2018
Localization of mitochondrial large ribosomal RNA in germ plasm of Xenopus embryos
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25738459
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Mitochondrial small ribosomal RNA is a component of germinal granules in Xenopus embryos
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25738459
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Mitochondrial stress signals revise an old aging theory
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25738459
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The impact of the number of cores on tissue microarray studies investigating prostate cancer biomarkers
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25738459
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.CMET.2015.02.009
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1147818
OpenCitations bibliographic resource ID
1147818
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1147818
PMCID
4350682
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1147818
PubMed ID
25738459
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1147818
ResearchGate publication ID
273122087
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit